Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1086
  Reference Plasmid   NZ_CP107290.1
  Reference Plasmid Size   9811
  Reference Plasmid GC Content   0.37
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0107044 ABBDLKMM_00009 5489 5 Skin 0.63 protein_coding synonymous_variant LOW 492C>T Pro164Pro
M0107045 ABBDLKMM_00009 5632 3 Skin 0.38 protein_coding missense_variant MODERATE 349G>T Ala117Ser
M0107046 ABBDLKMM_00009 5694 5 Skin 0.63 protein_coding missense_variant MODERATE 287C>T Thr96Ile
M0107047 ABBDLKMM_00010 6201 5 Skin 0.63 protein_coding missense_variant MODERATE 704G>A Arg235Gln
M0107048 ABBDLKMM_00010 6425 5 Skin 0.63 protein_coding synonymous_variant LOW 480A>C Val160Val
M0107049 ABBDLKMM_00010 6539 5 Skin 0.63 protein_coding synonymous_variant LOW 366T>C Ser122Ser
M0107050 ABBDLKMM_00010 6589 5 Skin 0.63 protein_coding missense_variant MODERATE 316G>A Val106Ile
M0107051 ABBDLKMM_00006 7096 4 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -4211T>G None
M0107052 ABBDLKMM_00006 7104 4 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -4219G>A None
M0107053 ABBDLKMM_00006 7105 4 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -4220A>C None
M0107054 ABBDLKMM_00006 7106 4 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -4221C>T None
M0107055 ABBDLKMM_00006 7146 4 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -4261G>T None
M0107056 ABBDLKMM_00006 7177 4 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -4292A>T None
M0107057 ABBDLKMM_00009 5825 4 Skin 0.50 protein_coding synonymous_variant LOW 156G>T Val52Val
M0107058 ABBDLKMM_00006 7217 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -4332C>T None
M0107059 ABBDLKMM_00006 7277 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -4392T>C None
M0107060 ABBDLKMM_00006 7278 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -4393C>T None
M0107061 ABBDLKMM_00006 7306 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -4421T>C None
M0107062 ABBDLKMM_00006 7320 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -4435G>A None
M0107063 ABBDLKMM_00006 7333 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -4448T>C None
M0107064 ABBDLKMM_00006 7400 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -4515C>T None
M0107065 ABBDLKMM_00006 7404 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -4519C>A None
M0107066 ABBDLKMM_00006 7446 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -4561C>T None
M0107067 ABBDLKMM_00006 7453 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -4568G>A None
M0107068 ABBDLKMM_00006 7475 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -4590C>A None
M0107069 ABBDLKMM_00006 7480 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -4595G>A None
M0107070 ABBDLKMM_00006 7534 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -4649G>T None
M0107071 ABBDLKMM_00011 7596 3 Skin 0.38 protein_coding splice_region_variant&stop_retained_variant LOW 722G>A Ter241Ter
M0107072 ABBDLKMM_00011 7629 3 Skin 0.38 protein_coding missense_variant MODERATE 689A>C Gln230Pro






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism
ABBDLKMM_00008 ARO:3000566 100 1.26e-264 1 373 1.0000 0.9443 tetracycline antibiotic major facilitator superfamily (MFS) antibiotic efflux pump antibiotic efflux






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
ABBDLKMM_00008 2.A.1.2.38 100 3.5e-205 1 373 1.0000 0.9443 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.1 The Major Facilitator Superfamily (MFS)