Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1091
  Reference Plasmid   NZ_CP110107.1
  Reference Plasmid Size   27395
  Reference Plasmid GC Content   0.36
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0195847 ENHLGDJN_00001 112 3 Gut 0.75 protein_coding downstream_gene_variant MODIFIER *437T>C None
M0195848 ENHLGDJN_00001 255 3 Gut 0.75 protein_coding downstream_gene_variant MODIFIER *294T>C None
M0195849 ENHLGDJN_00001 460 3 Gut 0.75 protein_coding downstream_gene_variant MODIFIER *89A>G None
M0195850 ENHLGDJN_00002 1091 3 Gut 0.75 protein_coding synonymous_variant LOW 150G>A Leu50Leu
M0195851 ENHLGDJN_00002 1103 3 Gut 0.75 protein_coding synonymous_variant LOW 138A>G Glu46Glu
M0195852 ENHLGDJN_00002 1143 3 Gut 0.75 protein_coding missense_variant MODERATE 98G>A Arg33Lys
M0195853 ENHLGDJN_00002 1157 3 Gut 0.75 protein_coding synonymous_variant LOW 84C>T Arg28Arg
M0195854 ENHLGDJN_00002 1200 3 Gut 0.75 protein_coding missense_variant MODERATE 41T>C Val14Ala
M0195855 ENHLGDJN_00002 1223 3 Gut 0.75 protein_coding synonymous_variant LOW 18G>A Glu6Glu
M0195856 ENHLGDJN_00003 1282 3 Gut 0.75 protein_coding synonymous_variant LOW 135A>G Leu45Leu
M0195857 ENHLGDJN_00003 1294 3 Gut 0.75 protein_coding synonymous_variant LOW 123C>T Gly41Gly
M0195858 ENHLGDJN_00003 1297 3 Gut 0.75 protein_coding synonymous_variant LOW 120T>C Thr40Thr
M0195859 ENHLGDJN_00003 1357 3 Gut 0.75 protein_coding synonymous_variant LOW 60A>C Gly20Gly
M0195860 ENHLGDJN_00003 1396 3 Gut 0.75 protein_coding synonymous_variant LOW 21A>T Ala7Ala
M0195861 ENHLGDJN_00003 1398 3 Gut 0.75 protein_coding missense_variant MODERATE 19G>A Ala7Thr
M0195862 ENHLGDJN_00001 1430 3 Gut 0.75 protein_coding upstream_gene_variant MODIFIER -522G>T None
M0195863 ENHLGDJN_00001 1458 3 Gut 0.75 protein_coding upstream_gene_variant MODIFIER -550C>A None
M0195864 ENHLGDJN_00004 1510 3 Gut 0.75 protein_coding missense_variant MODERATE 567A>G Ile189Met
M0195865 ENHLGDJN_00004 1627 3 Gut 0.75 protein_coding synonymous_variant LOW 450T>C Tyr150Tyr
M0195866 ENHLGDJN_00006 8109 3 Gut 0.75 protein_coding upstream_gene_variant MODIFIER -3894T>C None
M0195867 ENHLGDJN_00006 8115 3 Gut 0.75 protein_coding upstream_gene_variant MODIFIER -3900C>T None
M0195868 ENHLGDJN_00006 8181 3 Gut 0.75 protein_coding upstream_gene_variant MODIFIER -3966G>T None
M0195869 ENHLGDJN_00006 8240 3 Gut 0.75 protein_coding upstream_gene_variant MODIFIER -4025T>C None
M0195870 ENHLGDJN_00014 9251 3 Gut 0.75 protein_coding missense_variant MODERATE 826C>A His276Asn
M0195871 ENHLGDJN_00014 9543 3 Gut 0.75 protein_coding missense_variant MODERATE 1118A>C Glu373Ala
M0195872 ENHLGDJN_00008 9848 3 Gut 0.75 protein_coding upstream_gene_variant MODIFIER -4827T>C None
M0195873 ENHLGDJN_00015 10220 3 Gut 0.75 protein_coding synonymous_variant LOW 609T>C Phe203Phe
M0195874 ENHLGDJN_00015 10475 3 Gut 0.75 protein_coding synonymous_variant LOW 354A>C Ser118Ser
M0195875 ENHLGDJN_00016 10920 3 Gut 0.75 protein_coding missense_variant MODERATE 56C>T Thr19Met
M0195876 ENHLGDJN_00016 10930 3 Gut 0.75 protein_coding missense_variant MODERATE 66A>C Lys22Asn
M0195877 ENHLGDJN_00016 11016 3 Gut 0.75 protein_coding missense_variant MODERATE 152T>C Leu51Ser
M0195878 ENHLGDJN_00013 11901 3 Gut 0.75 protein_coding upstream_gene_variant MODIFIER -4158C>T None
M0195879 ENHLGDJN_00013 12052 3 Gut 0.75 protein_coding upstream_gene_variant MODIFIER -4309C>G None
M0195880 ENHLGDJN_00013 12074 3 Gut 0.75 protein_coding upstream_gene_variant MODIFIER -4331T>G None
M0195881 ENHLGDJN_00013 12082 3 Gut 0.75 protein_coding upstream_gene_variant MODIFIER -4339C>T None
M0195882 ENHLGDJN_00013 12145 3 Gut 0.75 protein_coding upstream_gene_variant MODIFIER -4402T>C None
M0195883 ENHLGDJN_00013 12154 3 Gut 0.75 protein_coding upstream_gene_variant MODIFIER -4411A>G None
M0195884 ENHLGDJN_00013 12159 3 Gut 0.75 protein_coding upstream_gene_variant MODIFIER -4416G>C None
M0195885 ENHLGDJN_00013 12266 3 Gut 0.75 protein_coding upstream_gene_variant MODIFIER -4523C>A None
M0195886 ENHLGDJN_00018 13103 3 Gut 0.75 protein_coding synonymous_variant LOW 528T>C Ser176Ser
M0195887 ENHLGDJN_00018 13166 3 Gut 0.75 protein_coding synonymous_variant LOW 591A>G Gly197Gly
M0195888 ENHLGDJN_00015 13330 3 Gut 0.75 protein_coding upstream_gene_variant MODIFIER -2502G>T None
M0195889 ENHLGDJN_00015 13737 3 Gut 0.75 protein_coding upstream_gene_variant MODIFIER -2909T>C None
M0195890 ENHLGDJN_00015 13763 3 Gut 0.75 protein_coding upstream_gene_variant MODIFIER -2935A>G None
M0195891 ENHLGDJN_00019 13828 3 Gut 0.75 protein_coding missense_variant MODERATE 91A>G Lys31Glu
M0195892 ENHLGDJN_00015 13987 3 Gut 0.75 protein_coding upstream_gene_variant MODIFIER -3159T>C None
M0195893 ENHLGDJN_00015 14203 3 Gut 0.75 protein_coding upstream_gene_variant MODIFIER -3375C>A None
M0195894 ENHLGDJN_00020 14429 3 Gut 0.75 protein_coding synonymous_variant LOW 6T>G Val2Val
M0195895 ENHLGDJN_00020 14471 3 Gut 0.75 protein_coding synonymous_variant LOW 48G>A Lys16Lys
M0195896 ENHLGDJN_00023 17665 3 Gut 0.75 protein_coding missense_variant MODERATE 589C>A Arg197Ser
M0195897 ENHLGDJN_00023 17692 3 Gut 0.75 protein_coding missense_variant MODERATE 562A>G Asn188Asp
M0195898 ENHLGDJN_00023 17693 3 Gut 0.75 protein_coding synonymous_variant LOW 561T>C Ile187Ile
M0195899 ENHLGDJN_00023 17879 3 Gut 0.75 protein_coding synonymous_variant LOW 375T>C Pro125Pro
M0195900 ENHLGDJN_00024 18315 3 Gut 0.75 protein_coding synonymous_variant LOW 300G>A Gly100Gly
M0195901 ENHLGDJN_00024 18357 3 Gut 0.75 protein_coding synonymous_variant LOW 258G>A Glu86Glu
M0195902 ENHLGDJN_00025 18628 3 Gut 0.75 protein_coding synonymous_variant LOW 1338G>A Lys446Lys
M0195903 ENHLGDJN_00025 18652 3 Gut 0.75 protein_coding missense_variant MODERATE 1314A>G Ile438Met
M0195904 ENHLGDJN_00025 18664 3 Gut 0.75 protein_coding synonymous_variant LOW 1302A>G Leu434Leu
M0195905 ENHLGDJN_00025 18718 3 Gut 0.75 protein_coding missense_variant MODERATE 1248C>A Phe416Leu
M0195906 ENHLGDJN_00025 18723 3 Gut 0.75 protein_coding synonymous_variant LOW 1243T>C Leu415Leu
M0195907 ENHLGDJN_00025 18773 3 Gut 0.75 protein_coding missense_variant MODERATE 1193C>T Thr398Met
M0195908 ENHLGDJN_00025 18895 3 Gut 0.75 protein_coding synonymous_variant LOW 1071T>C Ile357Ile
M0195909 ENHLGDJN_00025 19315 3 Gut 0.75 protein_coding synonymous_variant LOW 651G>A Leu217Leu
M0195910 ENHLGDJN_00021 20013 3 Gut 0.75 protein_coding upstream_gene_variant MODIFIER -4507T>G None
M0195911 ENHLGDJN_00021 20184 3 Gut 0.75 protein_coding upstream_gene_variant MODIFIER -4678T>G None
M0195912 ENHLGDJN_00026 20447 3 Gut 0.75 protein_coding missense_variant MODERATE 28A>G Ile10Val
M0195913 ENHLGDJN_00028 22214 3 Gut 0.75 protein_coding synonymous_variant LOW 750T>C Ile250Ile
M0195914 ENHLGDJN_00023 22802 3 Gut 0.75 protein_coding upstream_gene_variant MODIFIER -4549A>C None
M0195915 ENHLGDJN_00023 22830 3 Gut 0.75 protein_coding upstream_gene_variant MODIFIER -4577C>T None
M0195916 ENHLGDJN_00023 22932 3 Gut 0.75 protein_coding upstream_gene_variant MODIFIER -4679A>C None
M0195917 ENHLGDJN_00023 23221 3 Gut 0.75 protein_coding upstream_gene_variant MODIFIER -4968T>G None
M0195918 ENHLGDJN_00024 23276 3 Gut 0.75 protein_coding upstream_gene_variant MODIFIER -4662G>A None
M0195919 ENHLGDJN_00024 23277 3 Gut 0.75 protein_coding upstream_gene_variant MODIFIER -4663T>A None
M0195920 ENHLGDJN_00030 23467 3 Gut 0.75 protein_coding synonymous_variant LOW 99T>C Val33Val
M0195921 ENHLGDJN_00032 24550 3 Gut 0.75 protein_coding synonymous_variant LOW 300C>G Ser100Ser
M0195922 ENHLGDJN_00034 25182 3 Gut 0.75 protein_coding missense_variant MODERATE 418C>A Leu140Ile
M0195923 ENHLGDJN_00036 26095 3 Gut 0.75 protein_coding synonymous_variant LOW 273A>G Leu91Leu
M0195924 ENHLGDJN_00036 26344 3 Gut 0.75 protein_coding synonymous_variant LOW 24G>A Leu8Leu
M0195925 ENHLGDJN_00032 26915 3 Gut 0.75 protein_coding upstream_gene_variant MODIFIER -2066C>T None
M0195926 ENHLGDJN_00032 27243 3 Gut 0.75 protein_coding upstream_gene_variant MODIFIER -2394G>A None
M0195927 ENHLGDJN_00032 27283 3 Gut 0.75 protein_coding upstream_gene_variant MODIFIER -2434G>A None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
BFKKAMMH_00014 UYY91400.1|GT4 100 3.13e-295 1 387 1 1
ENHLGDJN_00014 UYY91400.1|GT4 100 3.13e-295 1 387 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term