Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1093
  Reference Plasmid   NZ_CP110402.1
  Reference Plasmid Size   2690
  Reference Plasmid GC Content   0.46
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0195930 KAPLIAPI_00001 905 5 Gut 0.38 protein_coding upstream_gene_variant MODIFIER -618C>T None
M0195931 KAPLIAPI_00001 917 5 Gut 0.38 protein_coding upstream_gene_variant MODIFIER -630A>G None
M0195932 KAPLIAPI_00001 924 5 Gut 0.38 protein_coding upstream_gene_variant MODIFIER -637T>A None
M0195933 KAPLIAPI_00001 939 5 Gut 0.38 protein_coding upstream_gene_variant MODIFIER -652C>G None
M0195934 KAPLIAPI_00001 959 5 Gut 0.38 protein_coding upstream_gene_variant MODIFIER -672A>T None
M0195935 KAPLIAPI_00001 988 5 Gut 0.38 protein_coding upstream_gene_variant MODIFIER -701G>T None
M0195936 KAPLIAPI_00001 1042 5 Gut 0.38 protein_coding upstream_gene_variant MODIFIER -755T>G None
M0195937 KAPLIAPI_00001 1049 5 Gut 0.38 protein_coding upstream_gene_variant MODIFIER -762A>G None
M0195938 KAPLIAPI_00001 1867 5 Gut 0.38 protein_coding upstream_gene_variant MODIFIER -1580C>A None
M0195939 KAPLIAPI_00001 1891 5 Gut 0.38 protein_coding upstream_gene_variant MODIFIER -1604G>T None
M0195940 KAPLIAPI_00001 1905 5 Gut 0.38 protein_coding upstream_gene_variant MODIFIER -1618A>G None
M0195941 KAPLIAPI_00001 153 4 Gut 0.31 protein_coding synonymous_variant LOW 135G>A Ala45Ala
M0195942 KAPLIAPI_00001 158 4 Gut 0.31 protein_coding missense_variant MODERATE 130A>C Ile44Leu
M0195943 KAPLIAPI_00001 182 4 Gut 0.31 protein_coding missense_variant MODERATE 106G>A Ala36Thr
M0195944 KAPLIAPI_00001 183 4 Gut 0.31 protein_coding synonymous_variant LOW 105C>T Ala35Ala
M0195945 KAPLIAPI_00001 195 4 Gut 0.31 protein_coding synonymous_variant LOW 93C>T Ala31Ala
M0195946 KAPLIAPI_00001 234 4 Gut 0.31 protein_coding synonymous_variant LOW 54G>A Gln18Gln
M0195947 KAPLIAPI_00001 252 4 Gut 0.31 protein_coding synonymous_variant LOW 36G>A Ala12Ala
M0195948 KAPLIAPI_00001 269 4 Gut 0.31 protein_coding missense_variant MODERATE 19A>G Thr7Ala
M0195949 KAPLIAPI_00001 292 4 Gut 0.31 protein_coding upstream_gene_variant MODIFIER -5G>A None
M0195950 KAPLIAPI_00001 293 4 Gut 0.31 protein_coding upstream_gene_variant MODIFIER -6A>G None
M0195951 KAPLIAPI_00001 386 4 Gut 0.31 protein_coding upstream_gene_variant MODIFIER -99T>A None
M0195952 KAPLIAPI_00001 535 4 Gut 0.31 protein_coding upstream_gene_variant MODIFIER -248G>A None
M0195953 KAPLIAPI_00001 549 4 Gut 0.31 protein_coding upstream_gene_variant MODIFIER -262C>T None
M0195954 KAPLIAPI_00002 692 4 Gut 0.31 protein_coding synonymous_variant LOW 120T>C Ser40Ser
M0195955 KAPLIAPI_00002 725 4 Gut 0.31 protein_coding missense_variant MODERATE 153C>A Asn51Lys
M0195956 KAPLIAPI_00002 752 4 Gut 0.31 protein_coding synonymous_variant LOW 180G>A Val60Val
M0195957 KAPLIAPI_00002 813 4 Gut 0.31 protein_coding missense_variant MODERATE 241A>G Ile81Val
M0195958 KAPLIAPI_00003 1126 4 Gut 0.31 protein_coding missense_variant MODERATE 722A>G Lys241Arg
M0195959 KAPLIAPI_00003 1316 4 Gut 0.31 protein_coding missense_variant MODERATE 532T>C Tyr178His
M0195960 KAPLIAPI_00003 1565 4 Gut 0.31 protein_coding missense_variant MODERATE 283A>C Ile95Leu
M0195961 KAPLIAPI_00003 1743 4 Gut 0.31 protein_coding missense_variant MODERATE 105G>A Met35Ile






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term