Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1103
  Reference Plasmid   NZ_CP115459.1
  Reference Plasmid Size   218419
  Reference Plasmid GC Content   0.63
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0108130 PBBBGMOH_00138 125486 3 Skin 0.09 protein_coding synonymous_variant LOW 171A>G Leu57Leu
M0108131 PBBBGMOH_00149 136556 3 Skin 0.09 protein_coding missense_variant MODERATE 1179G>C Met393Ile
M0108132 PBBBGMOH_00122 108007 3 Skin 0.09 protein_coding missense_variant MODERATE 506C>T Ala169Val






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group
PBBBGMOH_00047 Copper (Cu) 100 2.8e-63 1 125 1.0000 1.0000 prediction
PBBBGMOH_00083 Mercury (Hg) 100 4e-83 1 159 1.0000 1.0000 prediction
PBBBGMOH_00180 Arsenic (As) 72.5 2.3e-85 12 230 0.8952 0.9328 prediction
PBBBGMOH_00183 Arsenic (As) 100 1.8e-208 1 351 1.0000 1.0000 prediction
PBBBGMOH_00186 Arsenic (As) 100 2.6e-199 1 359 1.0000 1.0000 prediction
LELHNHPF_00047 Copper (Cu) 100 2.8e-63 1 125 1.0000 1.0000 prediction
LELHNHPF_00083 Mercury (Hg) 100 4e-83 1 159 1.0000 1.0000 prediction
LELHNHPF_00180 Arsenic (As) 72.5 2.3e-85 12 230 0.8952 0.9328 prediction
LELHNHPF_00183 Arsenic (As) 100 1.8e-208 1 351 1.0000 1.0000 prediction
LELHNHPF_00186 Arsenic (As) 100 2.6e-199 1 359 1.0000 1.0000 prediction






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
PBBBGMOH_00028 QHD69378.1|GH23 100 1.09e-144 1 222 1 1
PBBBGMOH_00075 BAV66381.1|GH130 99.8 0 1 433 1 1
PBBBGMOH_00198 QJR04043.1|GT4 100 6.71e-259 4 363 0.9917 1
PBBBGMOH_00200 QJR04041.1|GT2 100 4.72e-193 1 262 1 1
PBBBGMOH_00217 AYO78735.1|GT4 100 9.34e-293 1 397 1 1
PBBBGMOH_00220 AYO78732.1|GT4 100 3.21e-285 1 390 1 1
LELHNHPF_00028 QHD69378.1|GH23 100 1.09e-144 1 222 1 1
LELHNHPF_00075 BAV66381.1|GH130 99.8 0 1 433 1 1
LELHNHPF_00198 QJR04043.1|GT4 100 6.71e-259 4 363 0.9917 1
LELHNHPF_00200 QJR04041.1|GT2 100 4.72e-193 1 262 1 1
LELHNHPF_00217 AYO78735.1|GT4 100 9.34e-293 1 397 1 1
LELHNHPF_00220 AYO78732.1|GT4 100 3.21e-285 1 390 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
PBBBGMOH_00044 3.A.3.5.39 71.7 1.70000000000001e-310 13 785 0.9847 0.9607 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.3 The P-type ATPase (P-ATPase) Superfamily
LELHNHPF_00044 3.A.3.5.39 71.7 1.70000000000001e-310 13 785 0.9847 0.9607 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.3 The P-type ATPase (P-ATPase) Superfamily