Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1105
  Reference Plasmid   NZ_CP115760.1
  Reference Plasmid Size   142541
  Reference Plasmid GC Content   0.62
  Reference Plasmid Mobility Type   conjugative





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0108133 INKHIGMI_00062 57118 5 Skin 0.56 protein_coding missense_variant MODERATE 133C>A Leu45Ile
M0108134 INKHIGMI_00062 57218 4 Skin 0.44 protein_coding synonymous_variant LOW 33A>G Ala11Ala
M0108135 INKHIGMI_00062 57239 4 Skin 0.44 protein_coding missense_variant MODERATE 12G>C Leu4Phe
M0108136 INKHIGMI_00062 57241 3 Skin 0.33 protein_coding missense_variant MODERATE 10T>A Leu4Met
M0108137 INKHIGMI_00062 57245 3 Skin 0.33 protein_coding synonymous_variant LOW 6G>C Ala2Ala
M0108138 INKHIGMI_00062 57268 3 Skin 0.33 protein_coding upstream_gene_variant MODIFIER -18A>G None
M0108139 INKHIGMI_00062 57271 3 Skin 0.33 protein_coding upstream_gene_variant MODIFIER -21A>G None
M0108140 INKHIGMI_00064 58329 3 Skin 0.33 protein_coding missense_variant MODERATE 172G>A Gly58Arg






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group
INKHIGMI_00076 Mercury (Hg), Phenylmercury Acetate [class: Organo-mercury] 90.1 1.5e-239 1 476 1.0000 1.0000 prediction
INKHIGMI_00082 Mercury (Hg) 97.8 1.4e-71 1 137 1.0000 1.0000 prediction
INKHIGMI_00144 Copper (Cu) 79.6 1.7e-233 1 500 1.0000 1.0040 prediction






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
INKHIGMI_00070 WBU55185.1|GT2 100 1e-240 4 337 0.9911 1
INKHIGMI_00071 WBU55186.1|GT83 100 0 1 509 1 0.9732





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term