Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1117
  Reference Plasmid   NZ_CP117297.1
  Reference Plasmid Size   62042
  Reference Plasmid GC Content   0.41
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0196710 FCOKCANB_00007 7275 3 Gut 0.30 protein_coding upstream_gene_variant MODIFIER -3377C>T None
M0196711 FCOKCANB_00011 7659 3 Gut 0.30 protein_coding synonymous_variant LOW 252T>C His84His
M0196712 FCOKCANB_00011 8029 3 Gut 0.30 protein_coding missense_variant MODERATE 622G>A Ala208Thr
M0196713 FCOKCANB_00011 8066 3 Gut 0.30 protein_coding missense_variant MODERATE 659C>A Ala220Glu
M0196714 FCOKCANB_00011 8129 3 Gut 0.30 protein_coding missense_variant MODERATE 722G>A Gly241Asp
M0196715 FCOKCANB_00011 8319 3 Gut 0.30 protein_coding synonymous_variant LOW 912T>C Phe304Phe
M0196716 FCOKCANB_00074 59556 5 Gut 0.50 protein_coding upstream_gene_variant MODIFIER -665G>A None
M0196717 FCOKCANB_00074 59558 3 Gut 0.30 protein_coding upstream_gene_variant MODIFIER -667T>A None
M0196718 FCOKCANB_00074 59559 3 Gut 0.30 protein_coding upstream_gene_variant MODIFIER -668C>T None
M0196719 FCOKCANB_00074 59561 3 Gut 0.30 protein_coding upstream_gene_variant MODIFIER -670C>T None
M0196720 FCOKCANB_00074 59564 3 Gut 0.30 protein_coding upstream_gene_variant MODIFIER -673T>C None
M0196721 FCOKCANB_00078 60129 4 Gut 0.40 protein_coding synonymous_variant LOW 252T>C Val84Val
M0196722 FCOKCANB_00078 60156 3 Gut 0.30 protein_coding synonymous_variant LOW 279C>T Ala93Ala
M0196723 FCOKCANB_00078 60192 3 Gut 0.30 protein_coding synonymous_variant LOW 315G>T Gly105Gly
M0196724 FCOKCANB_00078 60198 3 Gut 0.30 protein_coding synonymous_variant LOW 321C>T Tyr107Tyr
M0196725 FCOKCANB_00078 60200 3 Gut 0.30 protein_coding missense_variant MODERATE 323G>A Arg108His
M0196726 FCOKCANB_00078 60201 3 Gut 0.30 protein_coding synonymous_variant LOW 324C>T Arg108Arg
M0196727 FCOKCANB_00074 60217 3 Gut 0.30 protein_coding upstream_gene_variant MODIFIER -1326A>G None
M0196728 FCOKCANB_00074 60218 3 Gut 0.30 protein_coding upstream_gene_variant MODIFIER -1327A>G None
M0196729 FCOKCANB_00074 60224 3 Gut 0.30 protein_coding upstream_gene_variant MODIFIER -1333A>G None
M0196730 FCOKCANB_00074 60241 3 Gut 0.30 protein_coding upstream_gene_variant MODIFIER -1350G>A None
M0196731 FCOKCANB_00074 60263 3 Gut 0.30 protein_coding upstream_gene_variant MODIFIER -1372C>A None
M0196732 FCOKCANB_00074 60294 3 Gut 0.30 protein_coding upstream_gene_variant MODIFIER -1403A>G None
M0196733 FCOKCANB_00079 60875 3 Gut 0.30 protein_coding missense_variant MODERATE 507T>A Asn169Lys
M0196734 FCOKCANB_00079 61030 3 Gut 0.30 protein_coding missense_variant MODERATE 662C>A Ala221Glu
M0196735 FCOKCANB_00079 61091 3 Gut 0.30 protein_coding synonymous_variant LOW 723C>T His241His
M0196736 FCOKCANB_00074 61454 3 Gut 0.30 protein_coding upstream_gene_variant MODIFIER -2563T>G None
M0196737 FCOKCANB_00074 61477 3 Gut 0.30 protein_coding upstream_gene_variant MODIFIER -2586C>T None
M0196738 FCOKCANB_00074 61486 3 Gut 0.30 protein_coding upstream_gene_variant MODIFIER -2595G>A None
M0196739 FCOKCANB_00074 61531 3 Gut 0.30 protein_coding upstream_gene_variant MODIFIER -2640T>C None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term