Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1119
  Reference Plasmid   NZ_CP117666.1
  Reference Plasmid Size   2761
  Reference Plasmid GC Content   0.47
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0196740 BIOOHMNN_00001 247 3 Gut 0.60 protein_coding synonymous_variant LOW 1143T>C Asp381Asp
M0196741 BIOOHMNN_00001 274 4 Gut 0.80 protein_coding synonymous_variant LOW 1116A>G Leu372Leu
M0196742 BIOOHMNN_00001 379 4 Gut 0.80 protein_coding synonymous_variant LOW 1011A>G Gly337Gly
M0196743 BIOOHMNN_00001 430 4 Gut 0.80 protein_coding synonymous_variant LOW 960C>A Pro320Pro
M0196744 BIOOHMNN_00001 466 5 Gut 1.00 protein_coding synonymous_variant LOW 924C>T Pro308Pro
M0196745 BIOOHMNN_00001 688 5 Gut 1.00 protein_coding synonymous_variant LOW 702A>G Val234Val
M0196746 BIOOHMNN_00003 39 4 Gut 0.80 protein_coding upstream_gene_variant MODIFIER -2218A>G None
M0196747 BIOOHMNN_00003 89 4 Gut 0.80 protein_coding upstream_gene_variant MODIFIER -2168T>C None
M0196748 BIOOHMNN_00003 96 3 Gut 0.60 protein_coding upstream_gene_variant MODIFIER -2161T>C None
M0196749 BIOOHMNN_00003 99 4 Gut 0.80 protein_coding upstream_gene_variant MODIFIER -2158A>C None
M0196750 BIOOHMNN_00003 106 3 Gut 0.60 protein_coding upstream_gene_variant MODIFIER -2151C>A None
M0196751 BIOOHMNN_00003 114 3 Gut 0.60 protein_coding upstream_gene_variant MODIFIER -2143A>T None
M0196752 BIOOHMNN_00003 126 4 Gut 0.80 protein_coding upstream_gene_variant MODIFIER -2131T>G None
M0196753 BIOOHMNN_00003 127 3 Gut 0.60 protein_coding upstream_gene_variant MODIFIER -2130C>T None
M0196754 BIOOHMNN_00003 128 3 Gut 0.60 protein_coding upstream_gene_variant MODIFIER -2129T>C None
M0196755 BIOOHMNN_00003 129 3 Gut 0.60 protein_coding upstream_gene_variant MODIFIER -2128G>A None
M0196756 BIOOHMNN_00003 141 3 Gut 0.60 protein_coding upstream_gene_variant MODIFIER -2116G>A None
M0196757 BIOOHMNN_00003 158 3 Gut 0.60 protein_coding upstream_gene_variant MODIFIER -2099C>T None
M0196758 BIOOHMNN_00003 185 3 Gut 0.60 protein_coding upstream_gene_variant MODIFIER -2072T>A None
M0196759 BIOOHMNN_00001 481 3 Gut 0.60 protein_coding synonymous_variant LOW 909C>T Arg303Arg
M0196760 BIOOHMNN_00001 517 3 Gut 0.60 protein_coding synonymous_variant LOW 873C>T Gly291Gly
M0196761 BIOOHMNN_00001 526 3 Gut 0.60 protein_coding synonymous_variant LOW 864C>T Asp288Asp
M0196762 BIOOHMNN_00001 616 3 Gut 0.60 protein_coding synonymous_variant LOW 774A>G Arg258Arg
M0196763 BIOOHMNN_00001 619 3 Gut 0.60 protein_coding synonymous_variant LOW 771G>A Thr257Thr
M0196764 BIOOHMNN_00001 628 3 Gut 0.60 protein_coding synonymous_variant LOW 762G>A Pro254Pro
M0196765 BIOOHMNN_00001 630 3 Gut 0.60 protein_coding missense_variant MODERATE 760C>T Pro254Ser
M0196766 BIOOHMNN_00001 697 3 Gut 0.60 protein_coding synonymous_variant LOW 693C>T Arg231Arg
M0196767 BIOOHMNN_00001 706 3 Gut 0.60 protein_coding synonymous_variant LOW 684A>G Lys228Lys
M0196768 BIOOHMNN_00001 709 3 Gut 0.60 protein_coding synonymous_variant LOW 681T>A Ala227Ala
M0196769 BIOOHMNN_00001 710 3 Gut 0.60 protein_coding missense_variant MODERATE 680C>G Ala227Gly
M0196770 BIOOHMNN_00001 712 3 Gut 0.60 protein_coding synonymous_variant LOW 678G>C Ala226Ala
M0196771 BIOOHMNN_00001 715 3 Gut 0.60 protein_coding synonymous_variant LOW 675C>T Tyr225Tyr
M0196772 BIOOHMNN_00001 718 3 Gut 0.60 protein_coding synonymous_variant LOW 672A>G Val224Val
M0196773 BIOOHMNN_00001 727 3 Gut 0.60 protein_coding synonymous_variant LOW 663G>T Thr221Thr
M0196774 BIOOHMNN_00001 757 3 Gut 0.60 protein_coding synonymous_variant LOW 633T>G Val211Val
M0196775 BIOOHMNN_00001 871 3 Gut 0.60 protein_coding synonymous_variant LOW 519C>T Leu173Leu
M0196776 BIOOHMNN_00001 994 3 Gut 0.60 protein_coding synonymous_variant LOW 396C>T Asp132Asp
M0196777 BIOOHMNN_00001 1076 4 Gut 0.80 protein_coding missense_variant MODERATE 314G>C Arg105Pro
M0196778 BIOOHMNN_00001 1158 4 Gut 0.80 protein_coding missense_variant MODERATE 232G>A Ala78Thr
M0196779 BIOOHMNN_00001 1234 4 Gut 0.80 protein_coding synonymous_variant LOW 156A>T Leu52Leu
M0196780 BIOOHMNN_00001 1251 4 Gut 0.80 protein_coding missense_variant MODERATE 139G>A Ala47Thr
M0196781 BIOOHMNN_00002 1531 3 Gut 0.60 protein_coding synonymous_variant LOW 162C>T Ser54Ser
M0196782 BIOOHMNN_00003 98 3 Gut 0.60 protein_coding upstream_gene_variant MODIFIER -2159G>A None
M0196783 BIOOHMNN_00002 1486 3 Gut 0.60 protein_coding synonymous_variant LOW 207C>T Ala69Ala






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term