Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1120
  Reference Plasmid   NZ_CP117885.1
  Reference Plasmid Size   33894
  Reference Plasmid GC Content   0.45
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0196784 ALLMAKEI_00020 17872 3 Gut 1.00 protein_coding synonymous_variant LOW 246C>T Gly82Gly
M0196785 ALLMAKEI_00020 17902 3 Gut 1.00 protein_coding synonymous_variant LOW 216C>T Ser72Ser
M0196786 ALLMAKEI_00020 17935 3 Gut 1.00 protein_coding synonymous_variant LOW 183G>A Arg61Arg
M0196787 ALLMAKEI_00020 17944 3 Gut 1.00 protein_coding synonymous_variant LOW 174A>C Ser58Ser
M0196788 ALLMAKEI_00020 17950 3 Gut 1.00 protein_coding synonymous_variant LOW 168G>A Ala56Ala
M0196789 ALLMAKEI_00020 17995 3 Gut 1.00 protein_coding synonymous_variant LOW 123T>C Phe41Phe
M0196790 ALLMAKEI_00020 18012 3 Gut 1.00 protein_coding missense_variant MODERATE 106A>G Ile36Val
M0196791 ALLMAKEI_00020 18034 3 Gut 1.00 protein_coding synonymous_variant LOW 84T>G Gly28Gly
M0196792 ALLMAKEI_00020 18039 3 Gut 1.00 protein_coding synonymous_variant LOW 79T>C Leu27Leu
M0196793 ALLMAKEI_00020 18040 3 Gut 1.00 protein_coding synonymous_variant LOW 78C>G Leu26Leu
M0196794 ALLMAKEI_00020 18042 3 Gut 1.00 protein_coding missense_variant MODERATE 76C>T Leu26Phe
M0196795 ALLMAKEI_00020 18043 3 Gut 1.00 protein_coding synonymous_variant LOW 75T>C Gly25Gly
M0196796 ALLMAKEI_00020 18055 3 Gut 1.00 protein_coding synonymous_variant LOW 63A>G Leu21Leu
M0196797 ALLMAKEI_00020 18057 3 Gut 1.00 protein_coding synonymous_variant LOW 61T>C Leu21Leu
M0196798 ALLMAKEI_00013 18123 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -4802A>G None
M0196799 ALLMAKEI_00013 18126 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -4805G>T None
M0196800 ALLMAKEI_00013 18135 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -4814A>G None
M0196801 ALLMAKEI_00013 18206 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -4885A>G None
M0196802 ALLMAKEI_00021 18400 3 Gut 1.00 protein_coding missense_variant MODERATE 595A>C Ser199Arg
M0196803 ALLMAKEI_00021 18457 3 Gut 1.00 protein_coding missense_variant MODERATE 538G>C Glu180Gln
M0196804 ALLMAKEI_00021 18527 3 Gut 1.00 protein_coding synonymous_variant LOW 468C>A Ile156Ile
M0196805 ALLMAKEI_00022 19067 3 Gut 1.00 protein_coding synonymous_variant LOW 1180T>C Leu394Leu
M0196806 ALLMAKEI_00022 19127 3 Gut 1.00 protein_coding missense_variant MODERATE 1120A>T Met374Leu
M0196807 ALLMAKEI_00022 19569 3 Gut 1.00 protein_coding missense_variant MODERATE 678G>T Leu226Phe
M0196808 ALLMAKEI_00022 20118 3 Gut 1.00 protein_coding synonymous_variant LOW 129G>A Thr43Thr
M0196809 ALLMAKEI_00023 20698 3 Gut 1.00 protein_coding synonymous_variant LOW 270G>A Thr90Thr
M0196810 ALLMAKEI_00023 20722 3 Gut 1.00 protein_coding synonymous_variant LOW 246T>C Ala82Ala
M0196811 ALLMAKEI_00023 20821 3 Gut 1.00 protein_coding synonymous_variant LOW 147G>A Lys49Lys
M0196812 ALLMAKEI_00023 20958 3 Gut 1.00 protein_coding missense_variant MODERATE 10G>A Asp4Asn
M0196813 ALLMAKEI_00019 20990 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -4813T>C None
M0196814 ALLMAKEI_00019 21013 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -4836T>C None
M0196815 ALLMAKEI_00019 21075 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -4898C>T None
M0196816 ALLMAKEI_00019 21080 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -4903T>C None
M0196817 ALLMAKEI_00019 21161 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -4984C>T None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term