Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1123
  Reference Plasmid   NZ_CP118033.1
  Reference Plasmid Size   84857
  Reference Plasmid GC Content   0.33
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0142871 OFBGDLFJ_00018 14893 3 Vaginal 0.43 protein_coding missense_variant MODERATE 164C>T Ala55Val
M0142872 OFBGDLFJ_00020 15685 3 Vaginal 0.43 protein_coding missense_variant MODERATE 310G>A Glu104Lys
M0142873 OFBGDLFJ_00021 16245 3 Vaginal 0.43 protein_coding missense_variant MODERATE 2878G>A Val960Ile
M0142874 OFBGDLFJ_00021 17057 3 Vaginal 0.43 protein_coding missense_variant MODERATE 2066A>C Glu689Ala
M0142875 OFBGDLFJ_00021 17941 3 Vaginal 0.43 protein_coding synonymous_variant LOW 1182C>T Thr394Thr
M0142876 OFBGDLFJ_00027 25510 3 Vaginal 0.43 protein_coding synonymous_variant LOW 1086T>C Ile362Ile
M0142877 OFBGDLFJ_00027 26324 3 Vaginal 0.43 protein_coding missense_variant MODERATE 272T>C Ile91Thr
M0142878 OFBGDLFJ_00028 27285 3 Vaginal 0.43 protein_coding missense_variant MODERATE 128T>C Val43Ala
M0142879 OFBGDLFJ_00029 27472 3 Vaginal 0.43 protein_coding synonymous_variant LOW 2169T>A Val723Val
M0142880 OFBGDLFJ_00029 27884 3 Vaginal 0.43 protein_coding missense_variant MODERATE 1757G>A Gly586Asp
M0142881 OFBGDLFJ_00029 29524 3 Vaginal 0.43 protein_coding synonymous_variant LOW 117G>A Pro39Pro
M0142882 OFBGDLFJ_00028 32218 3 Vaginal 0.43 protein_coding upstream_gene_variant MODIFIER -4806T>A None
M0142883 OFBGDLFJ_00032 33265 3 Vaginal 0.43 protein_coding missense_variant MODERATE 1651T>G Ser551Ala
M0142884 OFBGDLFJ_00032 34010 3 Vaginal 0.43 protein_coding synonymous_variant LOW 906C>A Pro302Pro
M0142885 OFBGDLFJ_00030 34987 3 Vaginal 0.43 protein_coding upstream_gene_variant MODIFIER -4659C>T None
M0142886 OFBGDLFJ_00030 34991 3 Vaginal 0.43 protein_coding upstream_gene_variant MODIFIER -4663T>G None
M0142887 OFBGDLFJ_00031 35705 3 Vaginal 0.43 protein_coding upstream_gene_variant MODIFIER -3542T>G None
M0142888 OFBGDLFJ_00031 35718 3 Vaginal 0.43 protein_coding upstream_gene_variant MODIFIER -3555A>G None
M0142889 OFBGDLFJ_00001 1550 3 Vaginal 0.43 protein_coding missense_variant MODERATE 1163A>C Asn388Thr
M0142890 OFBGDLFJ_00001 3787 3 Vaginal 0.43 protein_coding upstream_gene_variant MODIFIER -1075A>T None
M0142891 OFBGDLFJ_00004 4322 3 Vaginal 0.43 protein_coding stop_lost&splice_region_variant HIGH 415T>A Ter139Lysext*?
M0142892 OFBGDLFJ_00004 4514 3 Vaginal 0.43 protein_coding missense_variant MODERATE 223C>A His75Asn
M0142893 OFBGDLFJ_00083 69273 3 Vaginal 0.43 protein_coding missense_variant MODERATE 110A>G Asn37Ser
M0142894 OFBGDLFJ_00083 69406 3 Vaginal 0.43 protein_coding synonymous_variant LOW 243T>G Thr81Thr
M0142895 OFBGDLFJ_00084 69604 3 Vaginal 0.43 protein_coding missense_variant MODERATE 173A>G Lys58Arg
M0142896 OFBGDLFJ_00084 69845 3 Vaginal 0.43 protein_coding synonymous_variant LOW 414T>C Asn138Asn
M0142897 OFBGDLFJ_00086 70164 3 Vaginal 0.43 protein_coding missense_variant MODERATE 136G>A Val46Ile
M0142898 OFBGDLFJ_00091 75242 3 Vaginal 0.43 protein_coding synonymous_variant LOW 1531C>T Leu511Leu
M0142899 OFBGDLFJ_00089 75572 3 Vaginal 0.43 protein_coding upstream_gene_variant MODIFIER -4338T>C None
M0142900 OFBGDLFJ_00089 75972 3 Vaginal 0.43 protein_coding upstream_gene_variant MODIFIER -4738G>T None
M0142901 OFBGDLFJ_00092 76609 3 Vaginal 0.43 protein_coding missense_variant MODERATE 2042T>C Ile681Thr
M0142902 OFBGDLFJ_00092 76800 3 Vaginal 0.43 protein_coding synonymous_variant LOW 1851A>G Glu617Glu
M0142903 OFBGDLFJ_00092 77952 3 Vaginal 0.43 protein_coding synonymous_variant LOW 699T>C Asn233Asn
M0142904 OFBGDLFJ_00092 78239 3 Vaginal 0.43 protein_coding missense_variant MODERATE 412C>T Pro138Ser
M0142905 OFBGDLFJ_00094 79288 3 Vaginal 0.43 protein_coding missense_variant MODERATE 982T>A Cys328Ser
M0142906 OFBGDLFJ_00095 80733 3 Vaginal 0.43 protein_coding missense_variant MODERATE 38A>G Gln13Arg
M0142907 OFBGDLFJ_00096 81419 3 Vaginal 0.43 protein_coding missense_variant MODERATE 1852A>G Ser618Gly
M0142908 OFBGDLFJ_00096 82779 3 Vaginal 0.43 protein_coding synonymous_variant LOW 492T>C Asp164Asp
M0142909 OFBGDLFJ_00092 83484 3 Vaginal 0.43 protein_coding upstream_gene_variant MODIFIER -4834A>G None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term