Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1130
  Reference Plasmid   NZ_CP119171.1
  Reference Plasmid Size   213916
  Reference Plasmid GC Content   0.51
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0109548 KGJBLJPB_00119 134828 3 Skin 1.00 protein_coding missense_variant MODERATE 83G>C Arg28Pro
M0109549 KGJBLJPB_00119 134839 3 Skin 1.00 protein_coding missense_variant MODERATE 94C>A Leu32Ile
M0109550 KGJBLJPB_00119 134881 3 Skin 1.00 protein_coding missense_variant MODERATE 136A>G Thr46Ala
M0109551 KGJBLJPB_00119 135036 3 Skin 1.00 protein_coding synonymous_variant LOW 291G>A Glu97Glu
M0109552 KGJBLJPB_00119 135039 3 Skin 1.00 protein_coding synonymous_variant LOW 294G>A Pro98Pro
M0109553 KGJBLJPB_00119 135045 3 Skin 1.00 protein_coding synonymous_variant LOW 300A>G Lys100Lys
M0109554 KGJBLJPB_00119 135048 3 Skin 1.00 protein_coding synonymous_variant LOW 303C>A Ala101Ala
M0109555 KGJBLJPB_00119 135080 3 Skin 1.00 protein_coding missense_variant MODERATE 335A>G Gln112Arg
M0109556 KGJBLJPB_00119 135136 3 Skin 1.00 protein_coding missense_variant MODERATE 391G>A Asp131Asn
M0109557 KGJBLJPB_00119 135177 3 Skin 1.00 protein_coding synonymous_variant LOW 432A>G Lys144Lys
M0109558 KGJBLJPB_00119 135216 3 Skin 1.00 protein_coding synonymous_variant LOW 471C>T Pro157Pro
M0109559 KGJBLJPB_00119 135225 3 Skin 1.00 protein_coding synonymous_variant LOW 480G>T Ala160Ala
M0109560 KGJBLJPB_00119 135228 3 Skin 1.00 protein_coding synonymous_variant LOW 483A>G Glu161Glu
M0109561 KGJBLJPB_00119 135252 3 Skin 1.00 protein_coding synonymous_variant LOW 507A>G Val169Val
M0109562 KGJBLJPB_00119 135258 3 Skin 1.00 protein_coding synonymous_variant LOW 513G>T Ala171Ala
M0109563 KGJBLJPB_00119 135403 3 Skin 1.00 protein_coding missense_variant MODERATE 658A>G Asn220Asp
M0109564 KGJBLJPB_00119 135442 3 Skin 1.00 protein_coding missense_variant MODERATE 697A>G Ser233Gly
M0109565 KGJBLJPB_00120 135484 3 Skin 1.00 protein_coding upstream_gene_variant MODIFIER -3A>G None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group
KGJBLJPB_00136 Arsenic (As), Antimony (Sb) 85.1 1.1e-70 1 141 1.0000 1.0000 experiment
KGJBLJPB_00137 Arsenic (As) 90.9 3.7e-215 1 429 1.0000 1.0000 experiment
KGJBLJPB_00138 Arsenic (As) 82.2 1.2e-45 1 100 0.9528 0.8632 experiment
KGJBLJPB_00139 Arsenic (As) 90.9 9.6e-125 1 232 1.0000 1.0000 experiment
KGJBLJPB_00136 Arsenic (As) 87.9 2.9e-69 1 141 1.0000 1.0000 prediction
KGJBLJPB_00137 Arsenic (As), Antimony (Sb) 100 1.6e-232 1 429 1.0000 1.0000 prediction
KGJBLJPB_00138 Arsenic (As) 92.5 8.4e-53 1 106 1.0000 1.0000 prediction
KGJBLJPB_00139 Arsenic (As) 99.1 7.3e-134 1 232 1.0000 1.0000 prediction






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant
KGJBLJPB_00083 PHI:5228 BAHT 74.6 1.3e-186 1 386 0.9847 0.9438 rodents None heptosyltransferase reduced virulence
KGJBLJPB_00132 PHI:7262 cspC 70.8 2.9e-23 3 67 0.9028 0.9420 primates salmonellosis cold shock protein reduced virulence






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
KGJBLJPB_00001 QWC69394.1|PL17_1 99.8 0 1 665 1 1
KGJBLJPB_00057 QWC69427.1|GH23 96.1 6.7e-108 1 154 1 1
KGJBLJPB_00083 ASG38630.1|GT112 92 2.79e-293 1 389 0.9923 1
KGJBLJPB_00094 QWC69463.1|GH1 100 0 1 472 1 1
KGJBLJPB_00095 QWC69464.1|CBM35|GH5_41 99 0 1 731 1 1
KGJBLJPB_00131 QWC69348.1|GH0|GH94|GT84 99.7 0 1 2860 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
KGJBLJPB_00137 3.A.4.1.1 88.3 1.5e-212 1 429 1.0000 1.0000 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.4 The Arsenite-Antimonite (ArsAB) Efflux Family