Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1131
  Reference Plasmid   NZ_CP119173.1
  Reference Plasmid Size   12729
  Reference Plasmid GC Content   0.35
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0197060 PDAMJEAP_00007 4043 3 Gut 1.00 protein_coding missense_variant MODERATE 214A>G Lys72Glu
M0197061 PDAMJEAP_00007 4054 3 Gut 1.00 protein_coding missense_variant MODERATE 203T>C Leu68Ser
M0197062 PDAMJEAP_00007 4066 3 Gut 1.00 protein_coding missense_variant MODERATE 191G>A Arg64Gln
M0197063 PDAMJEAP_00007 4097 3 Gut 1.00 protein_coding missense_variant MODERATE 160G>T Ala54Ser
M0197064 PDAMJEAP_00007 4112 3 Gut 1.00 protein_coding synonymous_variant LOW 145T>C Leu49Leu
M0197065 PDAMJEAP_00008 4560 3 Gut 1.00 protein_coding missense_variant MODERATE 1283T>C Val428Ala
M0197066 PDAMJEAP_00008 4991 3 Gut 1.00 protein_coding synonymous_variant LOW 852C>T Leu284Leu
M0197067 PDAMJEAP_00008 5089 3 Gut 1.00 protein_coding missense_variant MODERATE 754G>T Ala252Ser
M0197068 PDAMJEAP_00008 5745 3 Gut 1.00 protein_coding missense_variant MODERATE 98G>A Arg33Lys
M0197069 PDAMJEAP_00008 5746 3 Gut 1.00 protein_coding missense_variant MODERATE 97A>G Arg33Gly
M0197070 PDAMJEAP_00008 5788 3 Gut 1.00 protein_coding missense_variant MODERATE 55C>T His19Tyr
M0197071 PDAMJEAP_00008 5809 3 Gut 1.00 protein_coding missense_variant MODERATE 34T>C Tyr12His
M0197072 PDAMJEAP_00007 5900 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -1644T>G None
M0197073 PDAMJEAP_00009 6273 3 Gut 1.00 protein_coding missense_variant MODERATE 361T>C Tyr121His






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant
PDAMJEAP_00008 PHI:8586 mntH1 77.2 6.4e-221 7 520 0.9790 0.9737 moths nosocomial infection divalent metal cation transporter unaffected pathogenicity






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term