Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1133
  Reference Plasmid   NZ_CP119342.1
  Reference Plasmid Size   41208
  Reference Plasmid GC Content   0.27
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0109566 IHNPCGDK_00021 16906 7 Skin 0.15 protein_coding synonymous_variant LOW 180C>A Arg60Arg
M0109567 IHNPCGDK_00022 17123 4 Skin 0.09 protein_coding missense_variant MODERATE 1614C>A Phe538Leu
M0109568 IHNPCGDK_00022 17931 4 Skin 0.09 protein_coding missense_variant MODERATE 806G>C Gly269Ala
M0109569 IHNPCGDK_00022 18067 3 Skin 0.07 protein_coding missense_variant MODERATE 670A>T Asn224Tyr
M0109570 IHNPCGDK_00023 19283 3 Skin 0.07 protein_coding synonymous_variant LOW 345G>A Glu115Glu
M0109571 IHNPCGDK_00023 19659 8 Skin 0.17 protein_coding missense_variant MODERATE 721G>A Val241Ile
M0109572 IHNPCGDK_00027 23716 5 Skin 0.11 protein_coding synonymous_variant LOW 648A>G Leu216Leu
M0109573 IHNPCGDK_00027 23725 5 Skin 0.11 protein_coding synonymous_variant LOW 639C>T Gly213Gly
M0109574 IHNPCGDK_00027 23815 3 Skin 0.07 protein_coding synonymous_variant LOW 549C>T Phe183Phe
M0109575 IHNPCGDK_00027 23818 3 Skin 0.07 protein_coding synonymous_variant LOW 546G>A Lys182Lys
M0109576 IHNPCGDK_00027 23822 3 Skin 0.07 protein_coding missense_variant MODERATE 542T>A Ile181Asn
M0109577 IHNPCGDK_00027 23833 3 Skin 0.07 protein_coding synonymous_variant LOW 531C>T Tyr177Tyr
M0109578 IHNPCGDK_00027 23857 4 Skin 0.09 protein_coding synonymous_variant LOW 507G>A Leu169Leu
M0109579 IHNPCGDK_00027 23863 4 Skin 0.09 protein_coding synonymous_variant LOW 501C>T Ser167Ser
M0109580 IHNPCGDK_00027 23869 3 Skin 0.07 protein_coding synonymous_variant LOW 495C>T Tyr165Tyr
M0109581 IHNPCGDK_00027 23871 3 Skin 0.07 protein_coding missense_variant MODERATE 493T>C Tyr165His
M0109582 IHNPCGDK_00027 23903 3 Skin 0.07 protein_coding missense_variant MODERATE 461G>A Arg154Lys
M0109583 IHNPCGDK_00027 23914 3 Skin 0.07 protein_coding synonymous_variant LOW 450A>T Pro150Pro
M0109584 IHNPCGDK_00027 23928 3 Skin 0.07 protein_coding missense_variant MODERATE 436G>A Glu146Lys
M0109585 IHNPCGDK_00027 23934 4 Skin 0.09 protein_coding synonymous_variant LOW 430C>T Leu144Leu
M0109586 IHNPCGDK_00027 23939 3 Skin 0.07 protein_coding missense_variant MODERATE 425A>G Asn142Ser
M0109587 IHNPCGDK_00027 23949 3 Skin 0.07 protein_coding missense_variant MODERATE 415C>T His139Tyr
M0109588 IHNPCGDK_00027 23959 3 Skin 0.07 protein_coding synonymous_variant LOW 405A>G Thr135Thr
M0109589 IHNPCGDK_00027 23960 4 Skin 0.09 protein_coding missense_variant MODERATE 404C>T Thr135Ile
M0109590 IHNPCGDK_00027 23965 3 Skin 0.07 protein_coding synonymous_variant LOW 399A>T Ile133Ile
M0109591 IHNPCGDK_00027 23977 3 Skin 0.07 protein_coding synonymous_variant LOW 387T>A Leu129Leu
M0109592 IHNPCGDK_00027 24018 3 Skin 0.07 protein_coding missense_variant MODERATE 346A>G Lys116Glu
M0109593 IHNPCGDK_00027 24028 3 Skin 0.07 protein_coding synonymous_variant LOW 336T>C Asn112Asn
M0109594 IHNPCGDK_00027 24034 3 Skin 0.07 protein_coding synonymous_variant LOW 330G>A Lys110Lys
M0109595 IHNPCGDK_00027 24037 3 Skin 0.07 protein_coding synonymous_variant LOW 327A>G Val109Val
M0109596 IHNPCGDK_00027 24057 3 Skin 0.07 protein_coding missense_variant MODERATE 307T>G Leu103Val
M0109597 IHNPCGDK_00027 24067 3 Skin 0.07 protein_coding synonymous_variant LOW 297C>T Ser99Ser
M0109598 IHNPCGDK_00027 24088 4 Skin 0.09 protein_coding synonymous_variant LOW 276G>T Leu92Leu
M0109599 IHNPCGDK_00027 24129 4 Skin 0.09 protein_coding missense_variant MODERATE 235A>G Lys79Glu
M0109600 IHNPCGDK_00027 24150 4 Skin 0.09 protein_coding missense_variant MODERATE 214G>A Val72Ile
M0109601 IHNPCGDK_00027 24167 4 Skin 0.09 protein_coding missense_variant MODERATE 197G>A Arg66Lys
M0109602 IHNPCGDK_00027 24202 3 Skin 0.07 protein_coding synonymous_variant LOW 162A>G Lys54Lys
M0109603 IHNPCGDK_00027 24216 3 Skin 0.07 protein_coding missense_variant MODERATE 148A>T Thr50Ser
M0109604 IHNPCGDK_00027 24226 3 Skin 0.07 protein_coding synonymous_variant LOW 138G>A Glu46Glu
M0109605 IHNPCGDK_00027 24238 3 Skin 0.07 protein_coding missense_variant MODERATE 126T>A Phe42Leu
M0109606 IHNPCGDK_00027 24270 3 Skin 0.07 protein_coding synonymous_variant LOW 94T>C Leu32Leu
M0109607 IHNPCGDK_00027 24271 3 Skin 0.07 protein_coding synonymous_variant LOW 93T>G Val31Val
M0109608 IHNPCGDK_00027 24274 3 Skin 0.07 protein_coding synonymous_variant LOW 90G>A Glu30Glu
M0109609 IHNPCGDK_00027 24286 3 Skin 0.07 protein_coding synonymous_variant LOW 78T>C Asn26Asn
M0109610 IHNPCGDK_00027 24289 3 Skin 0.07 protein_coding synonymous_variant LOW 75C>A Ile25Ile
M0109611 IHNPCGDK_00027 24292 3 Skin 0.07 protein_coding synonymous_variant LOW 72C>T Thr24Thr
M0109612 IHNPCGDK_00028 24367 4 Skin 0.09 protein_coding splice_region_variant&stop_retained_variant LOW 1112G>A Ter371Ter
M0109613 IHNPCGDK_00028 24402 4 Skin 0.09 protein_coding synonymous_variant LOW 1077A>T Val359Val
M0109614 IHNPCGDK_00028 24483 5 Skin 0.11 protein_coding synonymous_variant LOW 996T>C Leu332Leu
M0109615 IHNPCGDK_00028 24504 5 Skin 0.11 protein_coding synonymous_variant LOW 975A>T Ile325Ile
M0109616 IHNPCGDK_00028 24558 4 Skin 0.09 protein_coding synonymous_variant LOW 921T>C Pro307Pro
M0109617 IHNPCGDK_00028 24561 4 Skin 0.09 protein_coding synonymous_variant LOW 918T>C His306His
M0109618 IHNPCGDK_00028 24623 4 Skin 0.09 protein_coding missense_variant MODERATE 856A>C Asn286His
M0109619 IHNPCGDK_00028 24645 4 Skin 0.09 protein_coding synonymous_variant LOW 834G>T Gly278Gly
M0109620 IHNPCGDK_00028 24681 4 Skin 0.09 protein_coding synonymous_variant LOW 798A>C Ser266Ser
M0109621 IHNPCGDK_00028 24705 4 Skin 0.09 protein_coding synonymous_variant LOW 774C>G Val258Val
M0109622 IHNPCGDK_00028 24714 4 Skin 0.09 protein_coding synonymous_variant LOW 765T>C Asp255Asp
M0109623 IHNPCGDK_00028 24717 4 Skin 0.09 protein_coding synonymous_variant LOW 762C>T Tyr254Tyr
M0109624 IHNPCGDK_00028 24738 4 Skin 0.09 protein_coding synonymous_variant LOW 741C>T Ser247Ser
M0109625 IHNPCGDK_00028 24759 4 Skin 0.09 protein_coding synonymous_variant LOW 720G>T Gly240Gly
M0109626 IHNPCGDK_00028 24768 4 Skin 0.09 protein_coding synonymous_variant LOW 711G>A Leu237Leu
M0109627 IHNPCGDK_00028 24783 4 Skin 0.09 protein_coding synonymous_variant LOW 696T>C Asp232Asp
M0109628 IHNPCGDK_00028 24784 4 Skin 0.09 protein_coding missense_variant MODERATE 695A>G Asp232Gly
M0109629 IHNPCGDK_00028 24785 4 Skin 0.09 protein_coding missense_variant MODERATE 694G>A Asp232Asn
M0109630 IHNPCGDK_00028 24813 4 Skin 0.09 protein_coding synonymous_variant LOW 666T>C His222His
M0109631 IHNPCGDK_00028 24816 4 Skin 0.09 protein_coding synonymous_variant LOW 663C>T Gly221Gly
M0109632 IHNPCGDK_00028 24828 9 Skin 0.20 protein_coding synonymous_variant LOW 651C>T Asp217Asp
M0109633 IHNPCGDK_00028 24837 4 Skin 0.09 protein_coding synonymous_variant LOW 642T>C Ile214Ile
M0109634 IHNPCGDK_00028 24849 4 Skin 0.09 protein_coding synonymous_variant LOW 630T>C Arg210Arg
M0109635 IHNPCGDK_00028 24882 5 Skin 0.11 protein_coding synonymous_variant LOW 597C>A Thr199Thr
M0109636 IHNPCGDK_00028 24893 5 Skin 0.11 protein_coding synonymous_variant LOW 586C>T Leu196Leu
M0109637 IHNPCGDK_00028 24931 4 Skin 0.09 protein_coding missense_variant MODERATE 548A>C Glu183Ala
M0109638 IHNPCGDK_00028 24933 5 Skin 0.11 protein_coding synonymous_variant LOW 546G>A Glu182Glu
M0109639 IHNPCGDK_00028 24934 5 Skin 0.11 protein_coding missense_variant MODERATE 545A>G Glu182Gly
M0109640 IHNPCGDK_00028 24954 4 Skin 0.09 protein_coding synonymous_variant LOW 525G>T Ala175Ala
M0109641 IHNPCGDK_00028 24955 4 Skin 0.09 protein_coding missense_variant MODERATE 524C>T Ala175Val
M0109642 IHNPCGDK_00028 24960 4 Skin 0.09 protein_coding synonymous_variant LOW 519T>C Thr173Thr
M0109643 IHNPCGDK_00028 24974 4 Skin 0.09 protein_coding missense_variant MODERATE 505A>C Ile169Leu
M0109644 IHNPCGDK_00028 24993 4 Skin 0.09 protein_coding synonymous_variant LOW 486T>A Val162Val
M0109645 IHNPCGDK_00028 25015 4 Skin 0.09 protein_coding missense_variant MODERATE 464C>T Thr155Met
M0109646 IHNPCGDK_00028 25019 4 Skin 0.09 protein_coding missense_variant MODERATE 460A>G Arg154Gly
M0109647 IHNPCGDK_00028 25029 4 Skin 0.09 protein_coding synonymous_variant LOW 450T>C Asn150Asn
M0109648 IHNPCGDK_00028 25034 5 Skin 0.11 protein_coding missense_variant MODERATE 445A>G Ile149Val
M0109649 IHNPCGDK_00028 25078 6 Skin 0.13 protein_coding missense_variant MODERATE 401T>C Met134Thr
M0109650 IHNPCGDK_00028 25083 7 Skin 0.15 protein_coding missense_variant MODERATE 396G>A Met132Ile
M0109651 IHNPCGDK_00028 25116 13 Skin 0.28 protein_coding synonymous_variant LOW 363T>C Ser121Ser
M0109652 IHNPCGDK_00028 25155 6 Skin 0.13 protein_coding missense_variant MODERATE 324G>T Met108Ile
M0109653 IHNPCGDK_00028 25192 12 Skin 0.26 protein_coding missense_variant MODERATE 287A>G Glu96Gly
M0109654 IHNPCGDK_00028 25320 8 Skin 0.17 protein_coding missense_variant MODERATE 159T>A Asn53Lys
M0109655 IHNPCGDK_00028 25365 6 Skin 0.13 protein_coding missense_variant MODERATE 114G>T Lys38Asn
M0109656 IHNPCGDK_00028 25444 12 Skin 0.26 protein_coding missense_variant MODERATE 35C>T Thr12Ile
M0109657 IHNPCGDK_00025 25523 5 Skin 0.11 protein_coding upstream_gene_variant MODIFIER -3602T>C None
M0109658 IHNPCGDK_00025 25526 10 Skin 0.22 protein_coding upstream_gene_variant MODIFIER -3605A>G None
M0109659 IHNPCGDK_00025 20738 5 Skin 0.11 protein_coding missense_variant MODERATE 1184C>T Ser395Leu
M0109660 IHNPCGDK_00025 21032 7 Skin 0.15 protein_coding missense_variant MODERATE 890A>G Glu297Gly
M0109661 IHNPCGDK_00025 21598 18 Skin 0.39 protein_coding missense_variant MODERATE 324G>A Met108Ile
M0109662 IHNPCGDK_00027 23481 13 Skin 0.28 protein_coding missense_variant MODERATE 883C>A His295Asn
M0109663 IHNPCGDK_00027 24085 3 Skin 0.07 protein_coding synonymous_variant LOW 279A>C Ile93Ile
M0109664 IHNPCGDK_00025 21895 3 Skin 0.07 protein_coding synonymous_variant LOW 27A>T Leu9Leu
M0109665 IHNPCGDK_00026 21941 3 Skin 0.07 protein_coding synonymous_variant LOW 351G>A Leu117Leu
M0109666 IHNPCGDK_00027 23461 5 Skin 0.11 protein_coding synonymous_variant LOW 903T>C Asn301Asn
M0109667 IHNPCGDK_00025 25527 5 Skin 0.11 protein_coding upstream_gene_variant MODIFIER -3606A>G None
M0109668 IHNPCGDK_00025 25606 5 Skin 0.11 protein_coding upstream_gene_variant MODIFIER -3685G>T None
M0109669 IHNPCGDK_00027 22564 3 Skin 0.07 protein_coding synonymous_variant LOW 1800T>C Cys600Cys
M0109670 IHNPCGDK_00027 22750 5 Skin 0.11 protein_coding synonymous_variant LOW 1614G>A Lys538Lys
M0109671 IHNPCGDK_00027 23633 4 Skin 0.09 protein_coding missense_variant MODERATE 731C>G Ala244Gly
M0109672 IHNPCGDK_00027 23860 4 Skin 0.09 protein_coding synonymous_variant LOW 504A>G Gly168Gly
M0109673 IHNPCGDK_00025 21352 3 Skin 0.07 protein_coding missense_variant MODERATE 570G>T Leu190Phe
M0109674 IHNPCGDK_00018 20076 5 Skin 0.11 protein_coding upstream_gene_variant MODIFIER -4525G>T None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism
IHNPCGDK_00023 ARO:3000621 95 7.61e-187 1 281 1.0000 1.0000 penicillin beta-lactam BlaZ beta-lactamase antibiotic inactivation
JAFOCNKE_00023 ARO:3000621 95 7.61e-187 1 281 1.0000 1.0000 penicillin beta-lactam BlaZ beta-lactamase antibiotic inactivation






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term