Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1137
  Reference Plasmid   NZ_CP120000.1
  Reference Plasmid Size   28726
  Reference Plasmid GC Content   0.31
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0109675 NHAPGFMD_00026 26653 10 Skin 0.43 protein_coding missense_variant MODERATE 1024T>G Ser342Ala
M0109676 NHAPGFMD_00027 27849 8 Skin 0.35 protein_coding synonymous_variant LOW 579T>C Leu193Leu
M0109677 NHAPGFMD_00023 28564 9 Skin 0.39 protein_coding upstream_gene_variant MODIFIER -4666A>G None
M0109678 NHAPGFMD_00025 25772 4 Skin 0.17 protein_coding synonymous_variant LOW 435C>A Ile145Ile
M0109679 NHAPGFMD_00026 26888 3 Skin 0.13 protein_coding synonymous_variant LOW 789G>A Lys263Lys
M0109680 NHAPGFMD_00026 26959 4 Skin 0.17 protein_coding missense_variant MODERATE 718G>A Glu240Lys
M0109681 NHAPGFMD_00003 2079 6 Skin 0.26 protein_coding synonymous_variant LOW 294T>C Cys98Cys
M0109682 NHAPGFMD_00006 2243 6 Skin 0.26 protein_coding upstream_gene_variant MODIFIER -1720T>A None
M0109683 NHAPGFMD_00004 2464 3 Skin 0.13 protein_coding missense_variant MODERATE 493T>C Phe165Leu
M0109684 NHAPGFMD_00004 2506 3 Skin 0.13 protein_coding synonymous_variant LOW 451T>C Leu151Leu
M0109685 NHAPGFMD_00025 24890 5 Skin 0.22 protein_coding missense_variant MODERATE 1317T>A His439Gln
M0109686 NHAPGFMD_00025 25739 4 Skin 0.17 protein_coding synonymous_variant LOW 468T>C Ala156Ala
M0109687 NHAPGFMD_00026 26936 3 Skin 0.13 protein_coding synonymous_variant LOW 741T>A Pro247Pro






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term