Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1158
  Reference Plasmid   NZ_CP123987.1
  Reference Plasmid Size   191673
  Reference Plasmid GC Content   0.32
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0198318 EGPCEDEC_00047 56025 6 Gut 0.09 protein_coding upstream_gene_variant MODIFIER -939T>C None
M0198319 EGPCEDEC_00053 58724 5 Gut 0.08 protein_coding synonymous_variant LOW 84G>A Ser28Ser
M0198320 EGPCEDEC_00089 96220 4 Gut 0.06 protein_coding missense_variant MODERATE 158A>G Glu53Gly
M0198321 EGPCEDEC_00008 12569 8 Gut 0.12 protein_coding synonymous_variant LOW 591T>C Tyr197Tyr
M0198322 EGPCEDEC_00009 13339 7 Gut 0.11 protein_coding missense_variant MODERATE 553A>G Lys185Glu
M0198323 EGPCEDEC_00016 19366 5 Gut 0.08 protein_coding missense_variant MODERATE 372A>T Glu124Asp
M0198324 EGPCEDEC_00040 47052 3 Gut 0.05 protein_coding missense_variant MODERATE 533C>T Pro178Leu
M0198325 EGPCEDEC_00065 68604 4 Gut 0.06 protein_coding upstream_gene_variant MODIFIER -154A>G None
M0198326 EGPCEDEC_00066 72887 6 Gut 0.09 protein_coding upstream_gene_variant MODIFIER -2329G>A None
M0198327 EGPCEDEC_00072 77798 3 Gut 0.05 protein_coding missense_variant MODERATE 443T>C Ile148Thr
M0198328 EGPCEDEC_00074 79600 3 Gut 0.05 protein_coding missense_variant MODERATE 1330A>G Ser444Gly
M0198329 EGPCEDEC_00071 81542 3 Gut 0.05 protein_coding upstream_gene_variant MODIFIER -4539T>C None
M0198330 EGPCEDEC_00097 103389 6 Gut 0.09 protein_coding synonymous_variant LOW 786G>A Lys262Lys
M0198331 EGPCEDEC_00099 107800 3 Gut 0.05 protein_coding missense_variant MODERATE 8A>G Asn3Ser
M0198332 EGPCEDEC_00099 109966 4 Gut 0.06 protein_coding missense_variant MODERATE 2174G>A Arg725His
M0198333 EGPCEDEC_00114 121320 4 Gut 0.06 protein_coding synonymous_variant LOW 174C>T Val58Val
M0198334 EGPCEDEC_00127 128810 4 Gut 0.06 protein_coding missense_variant MODERATE 602T>C Val201Ala
M0198335 EGPCEDEC_00122 130260 3 Gut 0.05 protein_coding upstream_gene_variant MODIFIER -4865G>A None
M0198336 EGPCEDEC_00122 130267 3 Gut 0.05 protein_coding upstream_gene_variant MODIFIER -4872G>A None
M0198337 EGPCEDEC_00122 130330 3 Gut 0.05 protein_coding upstream_gene_variant MODIFIER -4935A>G None
M0198338 EGPCEDEC_00091 97478 3 Gut 0.05 protein_coding missense_variant MODERATE 409G>A Glu137Lys
M0198339 EGPCEDEC_00091 97833 4 Gut 0.06 protein_coding synonymous_variant LOW 54T>C Gly18Gly
M0198340 EGPCEDEC_00091 101905 3 Gut 0.05 protein_coding upstream_gene_variant MODIFIER -4019T>C None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
EGPCEDEC_00159 WGT61075.1|GH1 100 0 1 474 1 0.9937





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
EGPCEDEC_00130 2.A.21.3.20 74.5 5.1e-207 1 498 0.9940 0.9960 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.21 The Solute:Sodium Symporter (SSS) Family