Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1177
  Reference Plasmid   NZ_CP128833.1
  Reference Plasmid Size   769297
  Reference Plasmid GC Content   0.28
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0199209 DOCBAAGI_00063 82744 3 Gut 0.05 protein_coding synonymous_variant LOW 240G>A Val80Val
M0199210 DOCBAAGI_00065 85629 4 Gut 0.07 protein_coding missense_variant MODERATE 1349A>T His450Leu
M0199211 DOCBAAGI_00034 50672 3 Gut 0.05 protein_coding missense_variant MODERATE 1255C>G Gln419Glu
M0199212 DOCBAAGI_00052 71919 3 Gut 0.05 protein_coding synonymous_variant LOW 447A>G Arg149Arg
M0199213 DOCBAAGI_00067 90443 3 Gut 0.05 protein_coding upstream_gene_variant MODIFIER -2424G>A None
M0199214 DOCBAAGI_00067 90532 3 Gut 0.05 protein_coding upstream_gene_variant MODIFIER -2513G>A None
M0199215 DOCBAAGI_00067 91604 3 Gut 0.05 protein_coding upstream_gene_variant MODIFIER -3585A>C None
M0199216 DOCBAAGI_00070 92049 3 Gut 0.05 protein_coding synonymous_variant LOW 387G>A Thr129Thr
M0199217 DOCBAAGI_00070 92169 3 Gut 0.05 protein_coding missense_variant MODERATE 507A>C Leu169Phe
M0199218 DOCBAAGI_00070 92217 3 Gut 0.05 protein_coding synonymous_variant LOW 555C>T Tyr185Tyr
M0199219 DOCBAAGI_00070 92218 3 Gut 0.05 protein_coding missense_variant MODERATE 556G>A Asp186Asn
M0199220 DOCBAAGI_00070 92284 3 Gut 0.05 protein_coding missense_variant MODERATE 622G>A Glu208Lys
M0199221 DOCBAAGI_00070 92327 3 Gut 0.05 protein_coding missense_variant MODERATE 665T>A Ile222Lys
M0199222 DOCBAAGI_00070 92385 3 Gut 0.05 protein_coding synonymous_variant LOW 723C>T Ile241Ile
M0199223 DOCBAAGI_00070 92389 3 Gut 0.05 protein_coding missense_variant MODERATE 727G>T Val243Leu
M0199224 DOCBAAGI_00070 92517 3 Gut 0.05 protein_coding synonymous_variant LOW 855A>G Glu285Glu
M0199225 DOCBAAGI_00070 92662 3 Gut 0.05 protein_coding missense_variant MODERATE 1000G>A Val334Ile
M0199226 DOCBAAGI_00070 92716 3 Gut 0.05 protein_coding missense_variant MODERATE 1054A>G Lys352Glu
M0199227 DOCBAAGI_00070 92718 3 Gut 0.05 protein_coding missense_variant MODERATE 1056G>T Lys352Asn
M0199228 DOCBAAGI_00070 92719 3 Gut 0.05 protein_coding missense_variant MODERATE 1057C>A Gln353Lys
M0199229 DOCBAAGI_00070 92775 3 Gut 0.05 protein_coding synonymous_variant LOW 1113T>C Ile371Ile
M0199230 DOCBAAGI_00070 92814 3 Gut 0.05 protein_coding synonymous_variant LOW 1152C>T Ser384Ser
M0199231 DOCBAAGI_00070 92840 3 Gut 0.05 protein_coding missense_variant MODERATE 1178T>C Val393Ala
M0199232 DOCBAAGI_00070 92841 3 Gut 0.05 protein_coding synonymous_variant LOW 1179G>C Val393Val
M0199233 DOCBAAGI_00070 92901 3 Gut 0.05 protein_coding synonymous_variant LOW 1239A>G Lys413Lys
M0199234 DOCBAAGI_00070 92985 3 Gut 0.05 protein_coding synonymous_variant LOW 1323A>T Thr441Thr
M0199235 DOCBAAGI_00070 93150 3 Gut 0.05 protein_coding synonymous_variant LOW 1488A>G Lys496Lys
M0199236 DOCBAAGI_00070 93174 3 Gut 0.05 protein_coding synonymous_variant LOW 1512G>A Leu504Leu
M0199237 DOCBAAGI_00070 93219 3 Gut 0.05 protein_coding synonymous_variant LOW 1557G>A Val519Val
M0199238 DOCBAAGI_00070 93244 3 Gut 0.05 protein_coding missense_variant MODERATE 1582G>C Glu528Gln
M0199239 DOCBAAGI_00071 94329 3 Gut 0.05 protein_coding synonymous_variant LOW 177T>G Ala59Ala
M0199240 DOCBAAGI_00071 94687 3 Gut 0.05 protein_coding synonymous_variant LOW 535C>T Leu179Leu
M0199241 DOCBAAGI_00068 94883 3 Gut 0.05 protein_coding upstream_gene_variant MODIFIER -4612G>A None
M0199242 DOCBAAGI_00072 95638 3 Gut 0.05 protein_coding synonymous_variant LOW 507C>T Val169Val
M0199243 DOCBAAGI_00072 96001 3 Gut 0.05 protein_coding synonymous_variant LOW 870C>T Asp290Asp
M0199244 DOCBAAGI_00072 96133 3 Gut 0.05 protein_coding missense_variant MODERATE 1002G>T Met334Ile
M0199245 DOCBAAGI_00088 117477 3 Gut 0.05 protein_coding missense_variant MODERATE 223A>G Ile75Val
M0199246 DOCBAAGI_00088 117780 3 Gut 0.05 protein_coding missense_variant MODERATE 526A>G Thr176Ala
M0199247 DOCBAAGI_00088 117986 3 Gut 0.05 protein_coding synonymous_variant LOW 732T>A Ala244Ala
M0199248 DOCBAAGI_00088 118052 3 Gut 0.05 protein_coding synonymous_variant LOW 798G>A Arg266Arg
M0199249 DOCBAAGI_00088 118222 3 Gut 0.05 protein_coding missense_variant MODERATE 968A>G Lys323Arg
M0199250 DOCBAAGI_00092 122045 3 Gut 0.05 protein_coding synonymous_variant LOW 1077A>G Arg359Arg
M0199251 DOCBAAGI_00093 124472 3 Gut 0.05 protein_coding missense_variant MODERATE 814G>A Gly272Ser
M0199252 DOCBAAGI_00093 124670 3 Gut 0.05 protein_coding missense_variant MODERATE 616C>T His206Tyr
M0199253 DOCBAAGI_00096 127769 3 Gut 0.05 protein_coding missense_variant MODERATE 851T>A Ile284Lys
M0199254 DOCBAAGI_00096 127882 3 Gut 0.05 protein_coding missense_variant MODERATE 738T>G Ile246Met
M0199255 DOCBAAGI_00096 128113 3 Gut 0.05 protein_coding synonymous_variant LOW 507A>G Lys169Lys
M0199256 DOCBAAGI_00096 128116 3 Gut 0.05 protein_coding synonymous_variant LOW 504T>A Ile168Ile
M0199257 DOCBAAGI_00096 128118 3 Gut 0.05 protein_coding missense_variant MODERATE 502A>T Ile168Phe
M0199258 DOCBAAGI_00096 128122 3 Gut 0.05 protein_coding synonymous_variant LOW 498G>A Lys166Lys
M0199259 DOCBAAGI_00096 128134 3 Gut 0.05 protein_coding synonymous_variant LOW 486A>G Val162Val
M0199260 DOCBAAGI_00096 128403 3 Gut 0.05 protein_coding missense_variant MODERATE 217T>C Tyr73His
M0199261 DOCBAAGI_00096 128418 3 Gut 0.05 protein_coding missense_variant MODERATE 202C>G Pro68Ala
M0199262 DOCBAAGI_00096 128419 3 Gut 0.05 protein_coding synonymous_variant LOW 201C>T Asn67Asn
M0199263 DOCBAAGI_00097 129087 3 Gut 0.05 protein_coding synonymous_variant LOW 339G>A Gly113Gly
M0199264 DOCBAAGI_00097 129090 3 Gut 0.05 protein_coding synonymous_variant LOW 342C>T Asp114Asp
M0199265 DOCBAAGI_00097 129228 3 Gut 0.05 protein_coding missense_variant MODERATE 480G>T Met160Ile
M0199266 DOCBAAGI_00098 130542 3 Gut 0.05 protein_coding synonymous_variant LOW 39T>C Asp13Asp
M0199267 DOCBAAGI_00098 131387 3 Gut 0.05 protein_coding missense_variant MODERATE 884C>T Ala295Val
M0199268 DOCBAAGI_00098 131826 3 Gut 0.05 protein_coding synonymous_variant LOW 1323C>T Thr441Thr
M0199269 DOCBAAGI_00098 131979 3 Gut 0.05 protein_coding synonymous_variant LOW 1476A>G Gly492Gly
M0199270 DOCBAAGI_00098 132079 3 Gut 0.05 protein_coding missense_variant MODERATE 1576T>G Ser526Ala
M0199271 DOCBAAGI_00079 103055 3 Gut 0.05 protein_coding synonymous_variant LOW 681G>A Ser227Ser
M0199272 DOCBAAGI_00080 105115 3 Gut 0.05 protein_coding missense_variant MODERATE 286A>G Thr96Ala
M0199273 DOCBAAGI_00080 105328 3 Gut 0.05 protein_coding missense_variant MODERATE 499C>A His167Asn






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
DOCBAAGI_00079 BBK78922.1|GH31 100 0 1 781 1 1
DOCBAAGI_00080 QCJ08484.1|GH3 100 0 1 707 1 1
DOCBAAGI_00081 QMW92850.1|GH95 100 0 1 799 1 1
DOCBAAGI_00093 QCJ08496.1|GT4 100 0 1 622 1 1
DOCBAAGI_00095 QJU46739.1|GT2|GT4 100 0 1 609 1 1
DOCBAAGI_00100 QJU46744.1|GH12 100 1.16e-187 1 250 1 1
DOCBAAGI_00101 QJU46745.1|GH2 100 0 1 930 1 1
DOCBAAGI_00106 QJU46750.1|GH74 100 0 1 778 1 1
DOCBAAGI_00107 QJU46751.1|GH13_44 100 0 1 515 1 1
DOCBAAGI_00164 AXB86673.1|GH38 100 0 1 870 1 1
DOCBAAGI_00175 AXB86683.1|GH4 100 0 1 441 1 1
DOCBAAGI_00201 QCJ08596.1|CE4 100 6.84e-204 1 316 1 1
DOCBAAGI_00207 AXB86712.1|GT1 100 0 1 439 1 1
DOCBAAGI_00268 QCJ08657.1|GH13_29 100 0 1 552 1 1
DOCBAAGI_00348 AXB86842.1|GH170 100 1.04e-268 1 360 1 1
DOCBAAGI_00353 ANF16086.1|GH4 100 1.14999999850097e-315 1 436 1 1
DOCBAAGI_00470 QCJ08221.1|GH1 100 0 1 479 1 1
DOCBAAGI_00472 QJU46465.1|CBM4|GH16_3 100 0 1 1231 1 1
DOCBAAGI_00521 QJU46514.1|CE4 100 1.11e-186 1 252 1 1
DOCBAAGI_00547 QJU46536.1|GH53 100 4.36e-265 1 341 1 1
DOCBAAGI_00548 UZT08687.1|GH53 100 1.18e-250 1 326 1 1
DOCBAAGI_00550 AOR96158.1|GH42 100 0 1 687 1 1
DOCBAAGI_00572 APF21054.1|GH4 100 0 1 444 1 1
DOCBAAGI_00616 QCJ08353.1|CE8|PL9_1 100 0 1 1365 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
DOCBAAGI_00045 4.A.6.1.6 72.9 1e-136 1 325 1.0000 1.0000 4 Group Translocators 4.A Phosphotransfer-driven Group Translocators (PTS) 4.A.6 The PTS Mannose-Fructose-Sorbose (Man) Family
DOCBAAGI_00046 4.A.6.1.6 76 1.1e-107 1 268 1.0000 0.8364 4 Group Translocators 4.A Phosphotransfer-driven Group Translocators (PTS) 4.A.6 The PTS Mannose-Fructose-Sorbose (Man) Family
DOCBAAGI_00047 4.A.6.1.15 75.9 1.7e-136 1 303 1.0000 0.9439 4 Group Translocators 4.A Phosphotransfer-driven Group Translocators (PTS) 4.A.6 The PTS Mannose-Fructose-Sorbose (Man) Family