Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1219
  Reference Plasmid   NZ_CP136354.1
  Reference Plasmid Size   62970
  Reference Plasmid GC Content   0.34
  Reference Plasmid Mobility Type   conjugative





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0199703 FPDEBKCL_00032 35609 3 Gut 0.50 protein_coding upstream_gene_variant MODIFIER -4631G>T None
M0199704 FPDEBKCL_00041 36911 3 Gut 0.50 protein_coding synonymous_variant LOW 1276T>C Leu426Leu
M0199705 FPDEBKCL_00043 39047 3 Gut 0.50 protein_coding synonymous_variant LOW 15G>A Thr5Thr
M0199706 FPDEBKCL_00044 39285 3 Gut 0.50 protein_coding synonymous_variant LOW 1969C>T Leu657Leu
M0199707 FPDEBKCL_00044 39350 3 Gut 0.50 protein_coding missense_variant MODERATE 1904G>A Arg635Lys
M0199708 FPDEBKCL_00044 39397 3 Gut 0.50 protein_coding synonymous_variant LOW 1857A>G Gly619Gly
M0199709 FPDEBKCL_00044 39562 3 Gut 0.50 protein_coding synonymous_variant LOW 1692C>A Val564Val
M0199710 FPDEBKCL_00044 39598 3 Gut 0.50 protein_coding synonymous_variant LOW 1656A>G Ala552Ala
M0199711 FPDEBKCL_00044 39622 3 Gut 0.50 protein_coding synonymous_variant LOW 1632C>T Thr544Thr
M0199712 FPDEBKCL_00044 39637 3 Gut 0.50 protein_coding synonymous_variant LOW 1617T>C Cys539Cys
M0199713 FPDEBKCL_00044 39643 3 Gut 0.50 protein_coding synonymous_variant LOW 1611A>G Glu537Glu
M0199714 FPDEBKCL_00044 39817 3 Gut 0.50 protein_coding synonymous_variant LOW 1437G>A Gly479Gly
M0199715 FPDEBKCL_00044 39934 3 Gut 0.50 protein_coding synonymous_variant LOW 1320C>T Asn440Asn
M0199716 FPDEBKCL_00044 40060 3 Gut 0.50 protein_coding synonymous_variant LOW 1194A>G Gln398Gln
M0199717 FPDEBKCL_00044 40201 3 Gut 0.50 protein_coding synonymous_variant LOW 1053A>G Lys351Lys
M0199718 FPDEBKCL_00044 40220 3 Gut 0.50 protein_coding missense_variant MODERATE 1034T>A Ile345Lys
M0199719 FPDEBKCL_00044 40258 3 Gut 0.50 protein_coding synonymous_variant LOW 996G>A Thr332Thr
M0199720 FPDEBKCL_00044 40372 3 Gut 0.50 protein_coding synonymous_variant LOW 882C>T Leu294Leu
M0199721 FPDEBKCL_00044 40380 4 Gut 0.67 protein_coding missense_variant MODERATE 874A>G Ile292Val
M0199722 FPDEBKCL_00044 40420 3 Gut 0.50 protein_coding synonymous_variant LOW 834C>T Val278Val
M0199723 FPDEBKCL_00044 40429 3 Gut 0.50 protein_coding synonymous_variant LOW 825G>A Lys275Lys
M0199724 FPDEBKCL_00044 40438 3 Gut 0.50 protein_coding synonymous_variant LOW 816A>G Glu272Glu
M0199725 FPDEBKCL_00044 40471 3 Gut 0.50 protein_coding synonymous_variant LOW 783T>C Leu261Leu
M0199726 FPDEBKCL_00044 40573 3 Gut 0.50 protein_coding synonymous_variant LOW 681A>G Ala227Ala
M0199727 FPDEBKCL_00044 40747 3 Gut 0.50 protein_coding synonymous_variant LOW 507T>C Ile169Ile
M0199728 FPDEBKCL_00044 40771 3 Gut 0.50 protein_coding synonymous_variant LOW 483G>A Lys161Lys
M0199729 FPDEBKCL_00044 40834 3 Gut 0.50 protein_coding synonymous_variant LOW 420C>T Leu140Leu
M0199730 FPDEBKCL_00044 40977 3 Gut 0.50 protein_coding missense_variant MODERATE 277A>G Ile93Val
M0199731 FPDEBKCL_00044 40993 3 Gut 0.50 protein_coding synonymous_variant LOW 261T>C Thr87Thr
M0199732 FPDEBKCL_00044 41022 3 Gut 0.50 protein_coding missense_variant MODERATE 232C>T His78Tyr
M0199733 FPDEBKCL_00044 41023 3 Gut 0.50 protein_coding synonymous_variant LOW 231A>G Thr77Thr
M0199734 FPDEBKCL_00044 41053 3 Gut 0.50 protein_coding synonymous_variant LOW 201C>T Ile67Ile
M0199735 FPDEBKCL_00044 41101 3 Gut 0.50 protein_coding synonymous_variant LOW 153G>A Lys51Lys
M0199736 FPDEBKCL_00044 41107 3 Gut 0.50 protein_coding synonymous_variant LOW 147C>T Thr49Thr
M0199737 FPDEBKCL_00045 41574 3 Gut 0.50 protein_coding synonymous_variant LOW 1560C>T Arg520Arg
M0199738 FPDEBKCL_00045 41700 3 Gut 0.50 protein_coding synonymous_variant LOW 1434G>A Gly478Gly
M0199739 FPDEBKCL_00045 41730 3 Gut 0.50 protein_coding synonymous_variant LOW 1404C>T Asn468Asn
M0199740 FPDEBKCL_00045 41735 3 Gut 0.50 protein_coding synonymous_variant LOW 1399C>T Leu467Leu
M0199741 FPDEBKCL_00045 41802 3 Gut 0.50 protein_coding synonymous_variant LOW 1332G>A Ser444Ser
M0199742 FPDEBKCL_00045 41886 3 Gut 0.50 protein_coding synonymous_variant LOW 1248T>C Arg416Arg
M0199743 FPDEBKCL_00045 41907 3 Gut 0.50 protein_coding synonymous_variant LOW 1227A>T Gly409Gly
M0199744 FPDEBKCL_00045 42138 3 Gut 0.50 protein_coding synonymous_variant LOW 996T>A Ile332Ile
M0199745 FPDEBKCL_00045 42253 3 Gut 0.50 protein_coding missense_variant MODERATE 881C>T Ala294Val
M0199746 FPDEBKCL_00045 42752 3 Gut 0.50 protein_coding missense_variant MODERATE 382C>A Gln128Lys
M0199747 FPDEBKCL_00045 42909 3 Gut 0.50 protein_coding synonymous_variant LOW 225C>T Gly75Gly
M0199748 FPDEBKCL_00045 42917 3 Gut 0.50 protein_coding missense_variant MODERATE 217G>A Val73Ile
M0199749 FPDEBKCL_00045 42957 3 Gut 0.50 protein_coding synonymous_variant LOW 177T>G Arg59Arg
M0199750 FPDEBKCL_00045 42984 3 Gut 0.50 protein_coding synonymous_variant LOW 150G>A Leu50Leu
M0199751 FPDEBKCL_00045 42990 3 Gut 0.50 protein_coding synonymous_variant LOW 144C>T Asp48Asp
M0199752 FPDEBKCL_00046 43172 3 Gut 0.50 protein_coding synonymous_variant LOW 450C>T Ile150Ile
M0199753 FPDEBKCL_00046 43283 3 Gut 0.50 protein_coding synonymous_variant LOW 339A>G Val113Val
M0199754 FPDEBKCL_00046 43415 3 Gut 0.50 protein_coding synonymous_variant LOW 207A>G Val69Val
M0199755 FPDEBKCL_00043 43648 3 Gut 0.50 protein_coding upstream_gene_variant MODIFIER -4587G>A None
M0199756 FPDEBKCL_00043 43693 3 Gut 0.50 protein_coding upstream_gene_variant MODIFIER -4632A>C None
M0199757 FPDEBKCL_00047 43790 3 Gut 0.50 protein_coding missense_variant MODERATE 608T>G Val203Gly
M0199758 FPDEBKCL_00047 43798 3 Gut 0.50 protein_coding synonymous_variant LOW 600A>G Lys200Lys
M0199759 FPDEBKCL_00047 43942 3 Gut 0.50 protein_coding synonymous_variant LOW 456G>A Thr152Thr
M0199760 FPDEBKCL_00047 43943 3 Gut 0.50 protein_coding missense_variant MODERATE 455C>T Thr152Met
M0199761 FPDEBKCL_00047 44057 3 Gut 0.50 protein_coding missense_variant MODERATE 341C>T Pro114Leu
M0199762 FPDEBKCL_00047 44318 3 Gut 0.50 protein_coding missense_variant MODERATE 80C>T Ala27Val
M0199763 FPDEBKCL_00047 44329 3 Gut 0.50 protein_coding synonymous_variant LOW 69T>C Ile23Ile
M0199764 FPDEBKCL_00049 44694 3 Gut 0.50 protein_coding synonymous_variant LOW 525T>C Thr175Thr
M0199765 FPDEBKCL_00049 45155 3 Gut 0.50 protein_coding missense_variant MODERATE 64A>C Ile22Leu
M0199766 FPDEBKCL_00049 45182 3 Gut 0.50 protein_coding missense_variant MODERATE 37A>G Ile13Val
M0199767 FPDEBKCL_00049 45187 3 Gut 0.50 protein_coding missense_variant MODERATE 32C>T Ala11Val
M0199768 FPDEBKCL_00050 45419 3 Gut 0.50 protein_coding synonymous_variant LOW 2448T>A Thr816Thr
M0199769 FPDEBKCL_00050 45754 3 Gut 0.50 protein_coding synonymous_variant LOW 2113C>T Leu705Leu
M0199770 FPDEBKCL_00050 45783 3 Gut 0.50 protein_coding missense_variant MODERATE 2084A>C Asn695Thr
M0199771 FPDEBKCL_00050 47234 3 Gut 0.50 protein_coding synonymous_variant LOW 633G>C Arg211Arg
M0199772 FPDEBKCL_00050 47648 3 Gut 0.50 protein_coding synonymous_variant LOW 219G>A Leu73Leu
M0199773 FPDEBKCL_00051 47947 3 Gut 0.50 protein_coding synonymous_variant LOW 2322G>A Val774Val
M0199774 FPDEBKCL_00051 48106 3 Gut 0.50 protein_coding synonymous_variant LOW 2163A>G Gly721Gly
M0199775 FPDEBKCL_00051 48163 3 Gut 0.50 protein_coding synonymous_variant LOW 2106T>C Gly702Gly
M0199776 FPDEBKCL_00051 48226 3 Gut 0.50 protein_coding synonymous_variant LOW 2043C>T Asn681Asn
M0199777 FPDEBKCL_00051 48382 3 Gut 0.50 protein_coding synonymous_variant LOW 1887T>C Asp629Asp
M0199778 FPDEBKCL_00051 48709 3 Gut 0.50 protein_coding synonymous_variant LOW 1560T>C Asn520Asn
M0199779 FPDEBKCL_00051 48802 3 Gut 0.50 protein_coding synonymous_variant LOW 1467C>T Asp489Asp
M0199780 FPDEBKCL_00051 48923 3 Gut 0.50 protein_coding missense_variant MODERATE 1346C>T Thr449Ile
M0199781 FPDEBKCL_00051 48972 3 Gut 0.50 protein_coding missense_variant MODERATE 1297T>C Ser433Pro
M0199782 FPDEBKCL_00051 49000 3 Gut 0.50 protein_coding synonymous_variant LOW 1269C>A Val423Val
M0199783 FPDEBKCL_00051 49084 3 Gut 0.50 protein_coding synonymous_variant LOW 1185A>T Thr395Thr
M0199784 FPDEBKCL_00051 49092 3 Gut 0.50 protein_coding missense_variant MODERATE 1177T>C Phe393Leu
M0199785 FPDEBKCL_00051 49117 3 Gut 0.50 protein_coding synonymous_variant LOW 1152A>G Thr384Thr
M0199786 FPDEBKCL_00051 49203 3 Gut 0.50 protein_coding synonymous_variant LOW 1066T>C Leu356Leu
M0199787 FPDEBKCL_00051 49417 3 Gut 0.50 protein_coding synonymous_variant LOW 852T>C Pro284Pro
M0199788 FPDEBKCL_00051 49627 3 Gut 0.50 protein_coding synonymous_variant LOW 642T>C Tyr214Tyr
M0199789 FPDEBKCL_00051 49639 3 Gut 0.50 protein_coding synonymous_variant LOW 630C>T Phe210Phe
M0199790 FPDEBKCL_00051 49741 3 Gut 0.50 protein_coding synonymous_variant LOW 528T>C Ala176Ala
M0199791 FPDEBKCL_00051 49915 3 Gut 0.50 protein_coding synonymous_variant LOW 354G>T Ala118Ala
M0199792 FPDEBKCL_00051 49917 3 Gut 0.50 protein_coding missense_variant MODERATE 352G>T Ala118Ser
M0199793 FPDEBKCL_00051 49978 3 Gut 0.50 protein_coding synonymous_variant LOW 291G>A Arg97Arg
M0199794 FPDEBKCL_00051 49990 3 Gut 0.50 protein_coding synonymous_variant LOW 279T>C Asp93Asp
M0199795 FPDEBKCL_00051 50086 3 Gut 0.50 protein_coding synonymous_variant LOW 183A>G Lys61Lys
M0199796 FPDEBKCL_00051 50119 3 Gut 0.50 protein_coding synonymous_variant LOW 150G>A Gly50Gly
M0199797 FPDEBKCL_00051 50134 3 Gut 0.50 protein_coding synonymous_variant LOW 135T>C Ser45Ser
M0199798 FPDEBKCL_00051 50146 3 Gut 0.50 protein_coding synonymous_variant LOW 123C>T Ile41Ile
M0199799 FPDEBKCL_00051 50155 3 Gut 0.50 protein_coding synonymous_variant LOW 114A>G Gln38Gln
M0199800 FPDEBKCL_00052 50555 3 Gut 0.50 protein_coding synonymous_variant LOW 21T>C Phe7Phe
M0199801 FPDEBKCL_00053 50701 3 Gut 0.50 protein_coding missense_variant MODERATE 677C>T Ala226Val
M0199802 FPDEBKCL_00053 50805 3 Gut 0.50 protein_coding synonymous_variant LOW 573T>G Ala191Ala
M0199803 FPDEBKCL_00053 50856 3 Gut 0.50 protein_coding synonymous_variant LOW 522C>T Val174Val
M0199804 FPDEBKCL_00053 50880 3 Gut 0.50 protein_coding synonymous_variant LOW 498A>G Ala166Ala
M0199805 FPDEBKCL_00053 50967 3 Gut 0.50 protein_coding synonymous_variant LOW 411C>T Ala137Ala
M0199806 FPDEBKCL_00053 51012 3 Gut 0.50 protein_coding synonymous_variant LOW 366T>C Val122Val
M0199807 FPDEBKCL_00053 51186 3 Gut 0.50 protein_coding synonymous_variant LOW 192G>A Thr64Thr
M0199808 FPDEBKCL_00053 51335 3 Gut 0.50 protein_coding synonymous_variant LOW 43C>T Leu15Leu
M0199809 FPDEBKCL_00054 51591 3 Gut 0.50 protein_coding missense_variant MODERATE 98A>G Asp33Gly
M0199810 FPDEBKCL_00054 51594 3 Gut 0.50 protein_coding missense_variant MODERATE 95G>T Gly32Val
M0199811 FPDEBKCL_00054 51606 3 Gut 0.50 protein_coding missense_variant MODERATE 83T>A Ile28Asn
M0199812 FPDEBKCL_00054 51659 3 Gut 0.50 protein_coding synonymous_variant LOW 30T>C Asn10Asn
M0199813 FPDEBKCL_00055 51767 3 Gut 0.50 protein_coding synonymous_variant LOW 162C>T Ala54Ala
M0199814 FPDEBKCL_00055 51830 3 Gut 0.50 protein_coding synonymous_variant LOW 99C>T Gly33Gly
M0199815 FPDEBKCL_00055 51848 3 Gut 0.50 protein_coding synonymous_variant LOW 81C>G Val27Val
M0199816 FPDEBKCL_00050 51968 3 Gut 0.50 protein_coding upstream_gene_variant MODIFIER -4102T>C None
M0199817 FPDEBKCL_00056 52054 3 Gut 0.50 protein_coding missense_variant MODERATE 356C>T Thr119Ile
M0199818 FPDEBKCL_00056 52155 3 Gut 0.50 protein_coding synonymous_variant LOW 255T>C Asp85Asp
M0199819 FPDEBKCL_00056 52320 3 Gut 0.50 protein_coding synonymous_variant LOW 90A>G Lys30Lys
M0199820 FPDEBKCL_00050 52423 3 Gut 0.50 protein_coding upstream_gene_variant MODIFIER -4557A>G None
M0199821 FPDEBKCL_00057 52464 3 Gut 0.50 protein_coding missense_variant MODERATE 865A>C Ile289Leu
M0199822 FPDEBKCL_00057 52504 3 Gut 0.50 protein_coding synonymous_variant LOW 825G>A Val275Val
M0199823 FPDEBKCL_00057 52579 3 Gut 0.50 protein_coding synonymous_variant LOW 750G>A Gly250Gly
M0199824 FPDEBKCL_00057 52608 3 Gut 0.50 protein_coding synonymous_variant LOW 721T>C Leu241Leu
M0199825 FPDEBKCL_00057 52759 3 Gut 0.50 protein_coding synonymous_variant LOW 570A>G Glu190Glu
M0199826 FPDEBKCL_00057 52765 3 Gut 0.50 protein_coding synonymous_variant LOW 564A>G Val188Val
M0199827 FPDEBKCL_00057 52784 3 Gut 0.50 protein_coding missense_variant MODERATE 545T>C Ile182Thr
M0199828 FPDEBKCL_00057 52924 3 Gut 0.50 protein_coding synonymous_variant LOW 405T>G Val135Val
M0199829 FPDEBKCL_00057 52978 3 Gut 0.50 protein_coding synonymous_variant LOW 351A>C Gly117Gly
M0199830 FPDEBKCL_00057 52983 3 Gut 0.50 protein_coding missense_variant MODERATE 346G>A Val116Ile
M0199831 FPDEBKCL_00057 52992 3 Gut 0.50 protein_coding missense_variant MODERATE 337C>T Pro113Ser
M0199832 FPDEBKCL_00057 53258 3 Gut 0.50 protein_coding missense_variant MODERATE 71A>G Lys24Arg
M0199833 FPDEBKCL_00057 53263 3 Gut 0.50 protein_coding synonymous_variant LOW 66T>C Phe22Phe
M0199834 FPDEBKCL_00058 53399 3 Gut 0.50 protein_coding missense_variant MODERATE 829C>T Leu277Phe
M0199835 FPDEBKCL_00058 53424 3 Gut 0.50 protein_coding synonymous_variant LOW 804C>T Phe268Phe
M0199836 FPDEBKCL_00058 53845 3 Gut 0.50 protein_coding missense_variant MODERATE 383A>C Gln128Pro
M0199837 FPDEBKCL_00058 53944 3 Gut 0.50 protein_coding missense_variant MODERATE 284A>C Lys95Thr
M0199838 FPDEBKCL_00058 54021 3 Gut 0.50 protein_coding synonymous_variant LOW 207T>A Pro69Pro
M0199839 FPDEBKCL_00058 54068 3 Gut 0.50 protein_coding missense_variant MODERATE 160A>G Met54Val
M0199840 FPDEBKCL_00058 54089 3 Gut 0.50 protein_coding missense_variant MODERATE 139A>C Thr47Pro
M0199841 FPDEBKCL_00058 54111 3 Gut 0.50 protein_coding synonymous_variant LOW 117T>C Thr39Thr
M0199842 FPDEBKCL_00058 54201 3 Gut 0.50 protein_coding synonymous_variant LOW 27A>G Leu9Leu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition
FPDEBKCL_00060 VFG002164 AS 97.7 0 1 1305 1.0 1 Adherence aggregation substance PrgB/Asc10 experiment
FPDEBKCL_00060 VFG002164 AS 97.7 0 1 1305 1.0 1 Adherence aggregation substance PrgB/Asc10 prediction







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
FPDEBKCL_00025 BAG12399.1|GH24 99.8 0 1 595 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
FPDEBKCL_00039 3.A.7.19.1 93.3 4.2e-245 3 447 0.9955 0.7932 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.7 The Type IV (Conjugal DNA-Protein Transfer or VirB) Secretory Pathway (IVSP) Family
FPDEBKCL_00041 3.A.7.19.1 87 8e-286 1 561 1.0000 1.0000 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.7 The Type IV (Conjugal DNA-Protein Transfer or VirB) Secretory Pathway (IVSP) Family
FPDEBKCL_00044 3.A.7.19.1 99.4 0 1 719 1.0000 1.2816 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.7 The Type IV (Conjugal DNA-Protein Transfer or VirB) Secretory Pathway (IVSP) Family
FPDEBKCL_00045 3.A.7.19.1 99.3 0 1 609 1.0000 1.0856 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.7 The Type IV (Conjugal DNA-Protein Transfer or VirB) Secretory Pathway (IVSP) Family