Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1250
  Reference Plasmid   NZ_CP143643.1
  Reference Plasmid Size   13491
  Reference Plasmid GC Content   0.37
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0115078 IFIJFGAH_00001 231 9 Skin 0.64 protein_coding upstream_gene_variant MODIFIER -212C>G None
M0115079 IFIJFGAH_00001 285 10 Skin 0.71 protein_coding upstream_gene_variant MODIFIER -158A>G None
M0115080 IFIJFGAH_00001 345 12 Skin 0.86 protein_coding upstream_gene_variant MODIFIER -98G>A None
M0115081 IFIJFGAH_00001 348 9 Skin 0.64 protein_coding upstream_gene_variant MODIFIER -95C>T None
M0115082 IFIJFGAH_00001 414 9 Skin 0.64 protein_coding upstream_gene_variant MODIFIER -29G>A None
M0115083 IFIJFGAH_00001 416 10 Skin 0.71 protein_coding upstream_gene_variant MODIFIER -27T>C None
M0115084 IFIJFGAH_00001 423 10 Skin 0.71 protein_coding upstream_gene_variant MODIFIER -20T>A None
M0115085 IFIJFGAH_00001 497 13 Skin 0.93 protein_coding missense_variant MODERATE 55A>G Lys19Glu
M0115086 IFIJFGAH_00001 531 13 Skin 0.93 protein_coding missense_variant MODERATE 89G>A Arg30Lys
M0115087 IFIJFGAH_00001 580 10 Skin 0.71 protein_coding synonymous_variant LOW 138T>C Leu46Leu
M0115088 IFIJFGAH_00001 625 10 Skin 0.71 protein_coding synonymous_variant LOW 183A>T Ser61Ser
M0115089 IFIJFGAH_00001 664 10 Skin 0.71 protein_coding synonymous_variant LOW 222G>C Thr74Thr
M0115090 IFIJFGAH_00001 904 13 Skin 0.93 protein_coding synonymous_variant LOW 462A>G Glu154Glu
M0115091 IFIJFGAH_00001 956 5 Skin 0.36 protein_coding missense_variant MODERATE 514G>A Gly172Ser
M0115092 IFIJFGAH_00001 1089 9 Skin 0.64 protein_coding missense_variant MODERATE 647A>C Asn216Thr
M0115093 IFIJFGAH_00001 1148 10 Skin 0.71 protein_coding missense_variant MODERATE 706A>G Ile236Val
M0115094 IFIJFGAH_00001 1195 13 Skin 0.93 protein_coding synonymous_variant LOW 753T>C Ser251Ser
M0115095 IFIJFGAH_00001 1204 13 Skin 0.93 protein_coding synonymous_variant LOW 762G>T Gly254Gly
M0115096 IFIJFGAH_00001 1241 10 Skin 0.71 protein_coding missense_variant MODERATE 799G>A Val267Ile
M0115097 IFIJFGAH_00001 1248 10 Skin 0.71 protein_coding missense_variant MODERATE 806C>T Ser269Leu
M0115098 IFIJFGAH_00001 1261 13 Skin 0.93 protein_coding missense_variant MODERATE 819A>T Leu273Phe
M0115099 IFIJFGAH_00001 1265 10 Skin 0.71 protein_coding missense_variant MODERATE 823G>A Val275Ile
M0115100 IFIJFGAH_00001 1279 10 Skin 0.71 protein_coding synonymous_variant LOW 837T>C Ala279Ala
M0115101 IFIJFGAH_00001 1302 13 Skin 0.93 protein_coding missense_variant MODERATE 860G>A Gly287Glu
M0115102 IFIJFGAH_00001 1408 9 Skin 0.64 protein_coding synonymous_variant LOW 966A>G Val322Val
M0115103 IFIJFGAH_00001 1459 13 Skin 0.93 protein_coding synonymous_variant LOW 1017T>C His339His
M0115104 IFIJFGAH_00001 1498 10 Skin 0.71 protein_coding synonymous_variant LOW 1056C>T Phe352Phe
M0115105 IFIJFGAH_00001 1600 13 Skin 0.93 protein_coding synonymous_variant LOW 1158T>C Asp386Asp
M0115106 IFIJFGAH_00001 1722 10 Skin 0.71 protein_coding missense_variant MODERATE 1280G>A Ser427Asn
M0115107 IFIJFGAH_00001 1793 13 Skin 0.93 protein_coding synonymous_variant LOW 1351C>A Arg451Arg
M0115108 IFIJFGAH_00001 1816 13 Skin 0.93 protein_coding synonymous_variant LOW 1374C>T Asp458Asp
M0115109 IFIJFGAH_00001 1828 10 Skin 0.71 protein_coding missense_variant MODERATE 1386T>G Asp462Glu
M0115110 IFIJFGAH_00001 1846 10 Skin 0.71 protein_coding synonymous_variant LOW 1404G>A Leu468Leu
M0115111 IFIJFGAH_00001 1852 10 Skin 0.71 protein_coding synonymous_variant LOW 1410C>T Asp470Asp
M0115112 IFIJFGAH_00001 1855 13 Skin 0.93 protein_coding synonymous_variant LOW 1413G>A Glu471Glu
M0115113 IFIJFGAH_00001 1894 10 Skin 0.71 protein_coding synonymous_variant LOW 1452C>T Tyr484Tyr
M0115114 IFIJFGAH_00001 1906 9 Skin 0.64 protein_coding synonymous_variant LOW 1464A>C Gly488Gly
M0115115 IFIJFGAH_00001 259 3 Skin 0.21 protein_coding upstream_gene_variant MODIFIER -184G>A None
M0115116 IFIJFGAH_00001 344 3 Skin 0.21 protein_coding upstream_gene_variant MODIFIER -99A>G None
M0115117 IFIJFGAH_00001 388 3 Skin 0.21 protein_coding upstream_gene_variant MODIFIER -55A>G None
M0115118 IFIJFGAH_00001 405 3 Skin 0.21 protein_coding upstream_gene_variant MODIFIER -38T>A None
M0115119 IFIJFGAH_00001 406 3 Skin 0.21 protein_coding upstream_gene_variant MODIFIER -37G>A None
M0115120 IFIJFGAH_00001 420 3 Skin 0.21 protein_coding upstream_gene_variant MODIFIER -23T>C None
M0115121 IFIJFGAH_00001 562 4 Skin 0.29 protein_coding synonymous_variant LOW 120A>G Leu40Leu
M0115122 IFIJFGAH_00001 694 3 Skin 0.21 protein_coding missense_variant MODERATE 252A>T Leu84Phe
M0115123 IFIJFGAH_00001 790 3 Skin 0.21 protein_coding synonymous_variant LOW 348C>T Asn116Asn
M0115124 IFIJFGAH_00001 819 3 Skin 0.21 protein_coding missense_variant MODERATE 377C>A Thr126Asn
M0115125 IFIJFGAH_00001 850 3 Skin 0.21 protein_coding synonymous_variant LOW 408C>T Asn136Asn
M0115126 IFIJFGAH_00001 973 3 Skin 0.21 protein_coding missense_variant MODERATE 531T>A His177Gln
M0115127 IFIJFGAH_00001 1258 3 Skin 0.21 protein_coding synonymous_variant LOW 816G>T Leu272Leu
M0115128 IFIJFGAH_00001 1291 3 Skin 0.21 protein_coding synonymous_variant LOW 849T>C Asp283Asp
M0115129 IFIJFGAH_00001 1570 3 Skin 0.21 protein_coding synonymous_variant LOW 1128A>G Leu376Leu
M0115130 IFIJFGAH_00001 1601 3 Skin 0.21 protein_coding missense_variant MODERATE 1159C>T Arg387Cys
M0115131 IFIJFGAH_00001 1609 3 Skin 0.21 protein_coding synonymous_variant LOW 1167T>A Ile389Ile
M0115132 IFIJFGAH_00001 1688 3 Skin 0.21 protein_coding missense_variant MODERATE 1246A>C Lys416Gln
M0115133 IFIJFGAH_00001 1844 3 Skin 0.21 protein_coding missense_variant MODERATE 1402T>A Leu468Met
M0115134 IFIJFGAH_00001 1879 3 Skin 0.21 protein_coding synonymous_variant LOW 1437T>C Asn479Asn
M0115135 IFIJFGAH_00001 1948 3 Skin 0.21 protein_coding synonymous_variant LOW 1506A>T Ser502Ser
M0115136 IFIJFGAH_00001 1981 3 Skin 0.21 protein_coding synonymous_variant LOW 1539C>T His513His






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term