Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1272
  Reference Plasmid   NZ_CP146560.1
  Reference Plasmid Size   10328
  Reference Plasmid GC Content   0.48
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0205168 COEJFHBH_00002 1465 3 Gut 0.23 protein_coding synonymous_variant LOW 345A>G Gln115Gln
M0205169 COEJFHBH_00002 1528 6 Gut 0.46 protein_coding synonymous_variant LOW 282T>C Ile94Ile
M0205170 COEJFHBH_00002 1600 3 Gut 0.23 protein_coding synonymous_variant LOW 210A>G Gln70Gln
M0205171 COEJFHBH_00002 1605 3 Gut 0.23 protein_coding missense_variant MODERATE 205G>A Val69Ile
M0205172 COEJFHBH_00002 1608 3 Gut 0.23 protein_coding missense_variant MODERATE 202G>A Ala68Thr
M0205173 COEJFHBH_00003 2438 3 Gut 0.23 protein_coding missense_variant MODERATE 453G>C Glu151Asp
M0205174 COEJFHBH_00003 2467 3 Gut 0.23 protein_coding missense_variant MODERATE 482G>A Ser161Asn
M0205175 COEJFHBH_00003 2474 3 Gut 0.23 protein_coding synonymous_variant LOW 489T>C Thr163Thr
M0205176 COEJFHBH_00003 2476 3 Gut 0.23 protein_coding missense_variant MODERATE 491T>C Leu164Pro
M0205177 COEJFHBH_00003 2795 3 Gut 0.23 protein_coding synonymous_variant LOW 810G>T Leu270Leu
M0205178 COEJFHBH_00003 2863 3 Gut 0.23 protein_coding missense_variant MODERATE 878C>A Ala293Glu
M0205179 COEJFHBH_00004 3031 3 Gut 0.23 protein_coding synonymous_variant LOW 117T>A Thr39Thr
M0205180 COEJFHBH_00002 4322 8 Gut 0.62 protein_coding upstream_gene_variant MODIFIER -2513A>T None
M0205181 COEJFHBH_00002 4342 3 Gut 0.23 protein_coding upstream_gene_variant MODIFIER -2533C>A None
M0205182 COEJFHBH_00002 4740 12 Gut 0.92 protein_coding upstream_gene_variant MODIFIER -2931A>G None
M0205183 COEJFHBH_00002 5257 7 Gut 0.54 protein_coding upstream_gene_variant MODIFIER -3448G>A None
M0205184 COEJFHBH_00002 5272 4 Gut 0.31 protein_coding upstream_gene_variant MODIFIER -3463C>A None
M0205185 COEJFHBH_00006 5944 3 Gut 0.23 protein_coding missense_variant MODERATE 488A>C Glu163Ala
M0205186 COEJFHBH_00002 5222 3 Gut 0.23 protein_coding upstream_gene_variant MODIFIER -3413A>G None
M0205187 COEJFHBH_00007 6629 3 Gut 0.23 protein_coding synonymous_variant LOW 345A>G Gln115Gln
M0205188 COEJFHBH_00007 9486 3 Gut 0.23 protein_coding upstream_gene_variant MODIFIER -2513A>T None
M0205189 COEJFHBH_00002 4352 3 Gut 0.23 protein_coding upstream_gene_variant MODIFIER -2543C>T None
M0205190 COEJFHBH_00006 5939 3 Gut 0.23 protein_coding synonymous_variant LOW 483C>T Ala161Ala






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term