Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1280
  Reference Plasmid   NZ_CP147062.1
  Reference Plasmid Size   116680
  Reference Plasmid GC Content   0.45
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0205667 BGPMDHBO_00058 36842 3 Gut 0.33 protein_coding missense_variant MODERATE 443T>C Met148Thr
M0205668 BGPMDHBO_00058 36848 3 Gut 0.33 protein_coding missense_variant MODERATE 437G>A Arg146His
M0205669 BGPMDHBO_00065 42348 3 Gut 0.33 protein_coding synonymous_variant LOW 849T>C Asp283Asp
M0205670 BGPMDHBO_00065 42871 3 Gut 0.33 protein_coding missense_variant MODERATE 326G>A Ser109Asn
M0205671 BGPMDHBO_00066 43640 3 Gut 0.33 protein_coding missense_variant MODERATE 66G>T Lys22Asn
M0205672 BGPMDHBO_00067 44356 3 Gut 0.33 protein_coding missense_variant MODERATE 590G>A Ser197Asn
M0205673 BGPMDHBO_00068 44953 3 Gut 0.33 protein_coding missense_variant MODERATE 1669G>A Gly557Ser
M0205674 BGPMDHBO_00068 45511 3 Gut 0.33 protein_coding missense_variant MODERATE 1111G>A Asp371Asn
M0205675 BGPMDHBO_00068 46114 3 Gut 0.33 protein_coding missense_variant MODERATE 508A>G Ile170Val
M0205676 BGPMDHBO_00068 46553 3 Gut 0.33 protein_coding synonymous_variant LOW 69T>C Ser23Ser
M0205677 BGPMDHBO_00103 63474 3 Gut 0.33 protein_coding synonymous_variant LOW 156A>G Leu52Leu
M0205678 BGPMDHBO_00103 63532 3 Gut 0.33 protein_coding missense_variant MODERATE 98G>A Arg33Lys
M0205679 BGPMDHBO_00103 63533 3 Gut 0.33 protein_coding synonymous_variant LOW 97A>C Arg33Arg
M0205680 BGPMDHBO_00103 63536 3 Gut 0.33 protein_coding missense_variant MODERATE 94T>C Trp32Arg
M0205681 BGPMDHBO_00104 63919 3 Gut 0.33 protein_coding synonymous_variant LOW 210T>C Arg70Arg
M0205682 BGPMDHBO_00104 64013 3 Gut 0.33 protein_coding missense_variant MODERATE 116C>T Pro39Leu
M0205683 BGPMDHBO_00104 64033 3 Gut 0.33 protein_coding synonymous_variant LOW 96G>A Glu32Glu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition
BGPMDHBO_00001 VFG035923 Dispersin 90.9 8.2e-104 1 209 1.0 1 Others ATP-binding protein AatC experiment
BGPMDHBO_00002 VFG035916 Dispersin 90.6 3.4e-105 1 212 1.0 0.7766 Others AatB experiment
BGPMDHBO_00003 VFG035909 Dispersin 90.5 8.9e-211 1 412 1.0 1 Others outer membrane protein AatA experiment
BGPMDHBO_00004 VFG035902 Dispersin 91.8 7e-186 6 381 0.9869 1 Others permease AatP experiment
BGPMDHBO_00052 VFG034574 Dispersin 91.4 4.2e-57 1 116 1.0 1 Others dispersin experiment
BGPMDHBO_00158 VFG035929 Dispersin 89.6 1.7e-161 1 309 1.0 0.7649 Others AatD experiment
BGPMDHBO_00001 VFG035919 Dispersin 92.3 3.3e-104 1 209 1.0 1 Others ATP-binding protein AatC prediction
BGPMDHBO_00002 VFG035912 Dispersin 92 3.5e-106 1 212 1.0 0.7766 Others AatB prediction
BGPMDHBO_00003 VFG035909 Dispersin 90.5 6.7e-210 1 412 1.0 1 Others outer membrane protein AatA prediction
BGPMDHBO_00004 VFG035902 Dispersin 91.8 5.3e-185 6 381 0.9869 1 Others permease AatP prediction
BGPMDHBO_00052 VFG034574 Dispersin 91.4 3.1e-56 1 116 1.0 1 Others dispersin prediction
BGPMDHBO_00128 VFG041000 AAI/SCI-II T6SS 95.7 1.2e-102 1 188 1.0 1 Effector delivery system hypothetical protein prediction
BGPMDHBO_00132 VFG035429 AAI/SCI-II T6SS 88.4 0 1 842 1.0 0.9918 Effector delivery system type VI secretion system ATPase TssH prediction
BGPMDHBO_00133 VFG035428 AAI/SCI-II T6SS 80 0 1 1121 1.0 0.9885 Effector delivery system hypothetical protein prediction
BGPMDHBO_00134 VFG035422 AAI/SCI-II T6SS 75.5 9.6e-82 1 196 1.0 1 Effector delivery system DotU family type IV/VI secretion system protein prediction
BGPMDHBO_00143 VFG035409 AAI/SCI-II T6SS 85.6 4.7e-233 1 451 0.9934 0.9596 Effector delivery system type VI secretion system baseplate subunit TssK prediction
BGPMDHBO_00144 VFG035404 AAI/SCI-II T6SS 86.3 5.2e-90 1 183 1.0 1 Effector delivery system type VI secretion lipoprotein TssJ prediction
BGPMDHBO_00145 VFG035399 AAI/SCI-II T6SS 84.9 2e-178 1 358 1.0 1 Effector delivery system type VI secretion system protein TssA prediction
BGPMDHBO_00146 VFG035394 AAI/SCI-II T6SS 89.9 6.6e-47 1 99 1.0 1 Effector delivery system PAAR domain-containing protein prediction
BGPMDHBO_00147 VFG035389 AAI/SCI-II T6SS 77.8 4.8e-68 1 153 0.9871 0.9871 Effector delivery system hypothetical protein prediction
BGPMDHBO_00148 VFG035384 AAI/SCI-II T6SS 79.7 5.7e-307 23 679 0.9676 0.9955 Effector delivery system type VI secretion system tip protein VgrG prediction
BGPMDHBO_00149 VFG035379 AAI/SCI-II T6SS 86.5 1.4e-159 10 319 0.9718 1 Effector delivery system type VI secretion system baseplate subunit TssG prediction
BGPMDHBO_00150 VFG035374 AAI/SCI-II T6SS 86.7 0 1 600 1.0 1 Effector delivery system type VI secretion system baseplate subunit TssF prediction
BGPMDHBO_00151 VFG035369 AAI/SCI-II T6SS 88.6 1.3e-67 1 140 1.0 1 Effector delivery system hypothetical protein prediction
BGPMDHBO_00153 VFG035359 AAI/SCI-II T6SS 96.5 1.5e-280 1 492 1.0 1 Effector delivery system type VI secretion system contractile sheath large subunit prediction
BGPMDHBO_00154 VFG035354 AAI/SCI-II T6SS 91.8 4e-78 1 158 1.0 1 Effector delivery system type VI secretion system contractile sheath small subunit prediction
BGPMDHBO_00158 VFG035925 Dispersin 90.9 2.3e-162 1 309 1.0 0.7667 Others AatD prediction







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
BGPMDHBO_00116 QHR58273.1|GH23 97.8 7.16e-134 1 185 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term