Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1284
  Reference Plasmid   NZ_CP147684.1
  Reference Plasmid Size   35740
  Reference Plasmid GC Content   0.37
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0115925 JHIAIBJD_00031 27097 3 Skin 0.38 protein_coding missense_variant MODERATE 371G>A Gly124Asp
M0115926 JHIAIBJD_00031 27300 3 Skin 0.38 protein_coding missense_variant MODERATE 574T>C Ser192Pro
M0115927 JHIAIBJD_00033 28377 3 Skin 0.38 protein_coding missense_variant MODERATE 274C>A Leu92Ile
M0115928 JHIAIBJD_00033 30356 4 Skin 0.50 protein_coding synonymous_variant LOW 2253C>T Tyr751Tyr
M0115929 JHIAIBJD_00034 31201 4 Skin 0.50 protein_coding missense_variant MODERATE 536G>A Gly179Glu
M0115930 JHIAIBJD_00034 31204 4 Skin 0.50 protein_coding missense_variant MODERATE 539T>A Ile180Asn
M0115931 JHIAIBJD_00034 31206 4 Skin 0.50 protein_coding missense_variant MODERATE 541T>A Phe181Ile
M0115932 JHIAIBJD_00034 31207 4 Skin 0.50 protein_coding missense_variant MODERATE 542T>C Phe181Ser
M0115933 JHIAIBJD_00034 31217 4 Skin 0.50 protein_coding synonymous_variant LOW 552T>C Ala184Ala
M0115934 JHIAIBJD_00034 31231 4 Skin 0.50 protein_coding missense_variant MODERATE 566C>G Thr189Arg
M0115935 JHIAIBJD_00035 31725 4 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -175A>G None
M0115936 JHIAIBJD_00035 31857 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -43G>A None
M0115937 JHIAIBJD_00035 31948 3 Skin 0.38 protein_coding missense_variant MODERATE 49A>G Lys17Glu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term