Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1290
  Reference Plasmid   NZ_CP148329.1
  Reference Plasmid Size   2688
  Reference Plasmid GC Content   0.46
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0205751 AONPJFEC_00002 2650 11 Gut 0.85 protein_coding upstream_gene_variant MODIFIER -1394G>T None
M0205752 AONPJFEC_00001 513 11 Gut 0.85 protein_coding missense_variant MODERATE 382T>C Tyr128His
M0205753 AONPJFEC_00003 745 12 Gut 0.92 protein_coding upstream_gene_variant MODIFIER -796A>T None
M0205754 AONPJFEC_00003 780 12 Gut 0.92 protein_coding upstream_gene_variant MODIFIER -761A>G None
M0205755 AONPJFEC_00003 787 12 Gut 0.92 protein_coding upstream_gene_variant MODIFIER -754T>G None
M0205756 AONPJFEC_00003 841 12 Gut 0.92 protein_coding upstream_gene_variant MODIFIER -700G>T None
M0205757 AONPJFEC_00003 870 11 Gut 0.85 protein_coding upstream_gene_variant MODIFIER -671A>T None
M0205758 AONPJFEC_00003 905 11 Gut 0.85 protein_coding upstream_gene_variant MODIFIER -636T>A None
M0205759 AONPJFEC_00003 931 11 Gut 0.85 protein_coding upstream_gene_variant MODIFIER -610C>A None
M0205760 AONPJFEC_00002 963 11 Gut 0.85 protein_coding synonymous_variant LOW 294G>T Arg98Arg
M0205761 AONPJFEC_00002 984 11 Gut 0.85 protein_coding synonymous_variant LOW 273A>C Ile91Ile
M0205762 AONPJFEC_00002 1047 11 Gut 0.85 protein_coding synonymous_variant LOW 210G>A Leu70Leu
M0205763 AONPJFEC_00002 1052 11 Gut 0.85 protein_coding missense_variant MODERATE 205A>G Thr69Ala
M0205764 AONPJFEC_00002 1059 11 Gut 0.85 protein_coding synonymous_variant LOW 198C>A Arg66Arg
M0205765 AONPJFEC_00002 1061 11 Gut 0.85 protein_coding missense_variant MODERATE 196C>A Arg66Ser
M0205766 AONPJFEC_00002 1074 11 Gut 0.85 protein_coding synonymous_variant LOW 183T>G Leu61Leu
M0205767 AONPJFEC_00002 1077 11 Gut 0.85 protein_coding synonymous_variant LOW 180G>A Val60Val
M0205768 AONPJFEC_00002 1082 11 Gut 0.85 protein_coding synonymous_variant LOW 175A>C Arg59Arg
M0205769 AONPJFEC_00002 1083 11 Gut 0.85 protein_coding synonymous_variant LOW 174C>T Asp58Asp
M0205770 AONPJFEC_00002 1137 11 Gut 0.85 protein_coding synonymous_variant LOW 120T>C Ser40Ser
M0205771 AONPJFEC_00002 1281 11 Gut 0.85 protein_coding upstream_gene_variant MODIFIER -25C>A None
M0205772 AONPJFEC_00002 1294 11 Gut 0.85 protein_coding upstream_gene_variant MODIFIER -38C>T None
M0205773 AONPJFEC_00002 1372 11 Gut 0.85 protein_coding upstream_gene_variant MODIFIER -116G>A None
M0205774 AONPJFEC_00002 1417 11 Gut 0.85 protein_coding upstream_gene_variant MODIFIER -161C>T None
M0205775 AONPJFEC_00002 1423 11 Gut 0.85 protein_coding upstream_gene_variant MODIFIER -167A>T None
M0205776 AONPJFEC_00002 1425 11 Gut 0.85 protein_coding upstream_gene_variant MODIFIER -169T>C None
M0205777 AONPJFEC_00002 1433 11 Gut 0.85 protein_coding upstream_gene_variant MODIFIER -177C>T None
M0205778 AONPJFEC_00002 1443 11 Gut 0.85 protein_coding upstream_gene_variant MODIFIER -187T>C None
M0205779 AONPJFEC_00002 1444 11 Gut 0.85 protein_coding upstream_gene_variant MODIFIER -188T>G None
M0205780 AONPJFEC_00002 1446 11 Gut 0.85 protein_coding upstream_gene_variant MODIFIER -190G>A None
M0205781 AONPJFEC_00002 1450 11 Gut 0.85 protein_coding upstream_gene_variant MODIFIER -194C>T None
M0205782 AONPJFEC_00002 1461 11 Gut 0.85 protein_coding upstream_gene_variant MODIFIER -205C>G None
M0205783 AONPJFEC_00002 1466 11 Gut 0.85 protein_coding upstream_gene_variant MODIFIER -210T>C None
M0205784 AONPJFEC_00002 1468 11 Gut 0.85 protein_coding upstream_gene_variant MODIFIER -212G>A None
M0205785 AONPJFEC_00003 1594 11 Gut 0.85 protein_coding synonymous_variant LOW 54G>A Gln18Gln
M0205786 AONPJFEC_00003 1597 11 Gut 0.85 protein_coding synonymous_variant LOW 57T>C Ser19Ser
M0205787 AONPJFEC_00003 1615 11 Gut 0.85 protein_coding synonymous_variant LOW 75A>G Lys25Lys
M0205788 AONPJFEC_00003 1639 11 Gut 0.85 protein_coding synonymous_variant LOW 99G>A Glu33Glu
M0205789 AONPJFEC_00003 1645 11 Gut 0.85 protein_coding synonymous_variant LOW 105C>T Ala35Ala
M0205790 AONPJFEC_00003 1696 11 Gut 0.85 protein_coding synonymous_variant LOW 156A>C Ile52Ile
M0205791 AONPJFEC_00003 1698 11 Gut 0.85 protein_coding missense_variant MODERATE 158G>A Arg53Gln
M0205792 AONPJFEC_00003 1722 11 Gut 0.85 protein_coding missense_variant MODERATE 182A>G Asn61Ser






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term