Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1295
  Reference Plasmid   NZ_CP148411.1
  Reference Plasmid Size   96102
  Reference Plasmid GC Content   0.48
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0205816 GMHALAOG_00023 25248 3 Gut 1.00 protein_coding missense_variant MODERATE 242C>T Thr81Met
M0205817 GMHALAOG_00023 25251 3 Gut 1.00 protein_coding missense_variant MODERATE 239C>T Pro80Leu
M0205818 GMHALAOG_00025 26801 3 Gut 1.00 protein_coding synonymous_variant LOW 330T>C Ser110Ser
M0205819 GMHALAOG_00025 26945 3 Gut 1.00 protein_coding synonymous_variant LOW 186A>G Lys62Lys
M0205820 GMHALAOG_00026 27147 3 Gut 1.00 protein_coding synonymous_variant LOW 213C>T Thr71Thr
M0205821 GMHALAOG_00026 27171 3 Gut 1.00 protein_coding synonymous_variant LOW 189G>A Pro63Pro
M0205822 GMHALAOG_00026 27292 3 Gut 1.00 protein_coding missense_variant MODERATE 68A>C Glu23Ala
M0205823 GMHALAOG_00022 27433 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -2693T>C None
M0205824 GMHALAOG_00022 27583 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -2843A>G None
M0205825 GMHALAOG_00022 27584 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -2844C>T None
M0205826 GMHALAOG_00022 27589 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -2849A>G None
M0205827 GMHALAOG_00022 27611 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -2871A>G None
M0205828 GMHALAOG_00022 27631 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -2891G>A None
M0205829 GMHALAOG_00022 27634 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -2894G>A None
M0205830 GMHALAOG_00022 27700 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -2960G>A None
M0205831 GMHALAOG_00028 28358 3 Gut 1.00 protein_coding synonymous_variant LOW 75C>T Ala25Ala
M0205832 GMHALAOG_00028 28424 3 Gut 1.00 protein_coding synonymous_variant LOW 141G>A Leu47Leu
M0205833 GMHALAOG_00028 28439 3 Gut 1.00 protein_coding synonymous_variant LOW 156G>T Thr52Thr
M0205834 GMHALAOG_00028 28440 3 Gut 1.00 protein_coding missense_variant MODERATE 157G>C Asp53His
M0205835 GMHALAOG_00028 28451 3 Gut 1.00 protein_coding synonymous_variant LOW 168A>G Gln56Gln
M0205836 GMHALAOG_00028 28562 3 Gut 1.00 protein_coding synonymous_variant LOW 279T>C Arg93Arg
M0205837 GMHALAOG_00028 28571 3 Gut 1.00 protein_coding synonymous_variant LOW 288G>A Thr96Thr






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
GMHALAOG_00016 AJS09995.1|GH24 100 4.67e-139 1 185 1 1
GMHALAOG_00019 AYL89119.1|GH24 96.6 4.79999992156663e-317 1753 2255 0.2231 0.9031
GMHALAOG_00106 QGG67337.1|GH23 98.2 0 1 1140 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
GMHALAOG_00004 1.E.4.1.1 100 1.3e-54 1 109 1.0000 1.0000 1 Channels/Pores 1.E Holins 1.E.4 The LydA Holin (LydA Holin) Family