Annotation Categories of the Plasmid Cluster
Summary of the plasmid cluster
Basic Information about the Plasmid Cluster
Cluster Information |
Plasmid Cluster ID |
C1301 |
Reference Plasmid |
NZ_CP148747.1 |
Reference Plasmid Size |
119421 |
Reference Plasmid GC Content |
0.47 |
Reference Plasmid Mobility Type |
conjugative |
Mutation sites in the plasmid cluster
The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..
mutid |
gname |
pos |
count |
tissue |
frequnt |
biotype |
consequence |
impact |
nucchange |
aachange |
M0205859 |
CIGMFIEK_00079 |
64109 |
7 |
Gut |
0.78 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4897A>G |
None |
M0205860 |
CIGMFIEK_00079 |
64144 |
8 |
Gut |
0.89 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4932A>G |
None |
M0205861 |
CIGMFIEK_00080 |
64266 |
8 |
Gut |
0.89 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4533G>A |
None |
M0205862 |
CIGMFIEK_00080 |
64279 |
7 |
Gut |
0.78 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4546C>T |
None |
M0205863 |
CIGMFIEK_00080 |
64286 |
8 |
Gut |
0.89 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4553T>C |
None |
M0205864 |
CIGMFIEK_00080 |
64304 |
7 |
Gut |
0.78 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4571T>C |
None |
M0205865 |
CIGMFIEK_00080 |
64305 |
7 |
Gut |
0.78 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4572C>T |
None |
M0205866 |
CIGMFIEK_00080 |
64319 |
8 |
Gut |
0.89 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4586A>G |
None |
M0205867 |
CIGMFIEK_00080 |
64320 |
8 |
Gut |
0.89 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4587G>T |
None |
M0205868 |
CIGMFIEK_00088 |
64514 |
8 |
Gut |
0.89 |
protein_coding |
synonymous_variant |
LOW |
108G>A |
Ser36Ser |
M0205869 |
CIGMFIEK_00088 |
64547 |
7 |
Gut |
0.78 |
protein_coding |
synonymous_variant |
LOW |
141T>C |
Arg47Arg |
M0205870 |
CIGMFIEK_00088 |
64550 |
7 |
Gut |
0.78 |
protein_coding |
synonymous_variant |
LOW |
144T>C |
Thr48Thr |
M0205871 |
CIGMFIEK_00088 |
64565 |
7 |
Gut |
0.78 |
protein_coding |
synonymous_variant |
LOW |
159G>A |
Glu53Glu |
M0205872 |
CIGMFIEK_00088 |
64568 |
7 |
Gut |
0.78 |
protein_coding |
synonymous_variant |
LOW |
162G>A |
Leu54Leu |
M0205873 |
CIGMFIEK_00088 |
64571 |
7 |
Gut |
0.78 |
protein_coding |
synonymous_variant |
LOW |
165A>G |
Thr55Thr |
M0205874 |
CIGMFIEK_00088 |
64580 |
7 |
Gut |
0.78 |
protein_coding |
synonymous_variant |
LOW |
174C>T |
Ser58Ser |
M0205875 |
CIGMFIEK_00088 |
64592 |
8 |
Gut |
0.89 |
protein_coding |
synonymous_variant |
LOW |
186T>A |
Ala62Ala |
M0205876 |
CIGMFIEK_00088 |
64595 |
7 |
Gut |
0.78 |
protein_coding |
synonymous_variant |
LOW |
189G>A |
Glu63Glu |
M0205877 |
CIGMFIEK_00088 |
64628 |
7 |
Gut |
0.78 |
protein_coding |
synonymous_variant |
LOW |
222C>G |
Arg74Arg |
M0205878 |
CIGMFIEK_00088 |
64724 |
8 |
Gut |
0.89 |
protein_coding |
synonymous_variant |
LOW |
318T>C |
Val106Val |
M0205879 |
CIGMFIEK_00088 |
64751 |
7 |
Gut |
0.78 |
protein_coding |
synonymous_variant |
LOW |
345T>C |
Pro115Pro |
M0205880 |
CIGMFIEK_00088 |
64766 |
7 |
Gut |
0.78 |
protein_coding |
synonymous_variant |
LOW |
360C>A |
Ser120Ser |
M0205881 |
CIGMFIEK_00088 |
64790 |
8 |
Gut |
0.89 |
protein_coding |
synonymous_variant |
LOW |
384T>C |
Ser128Ser |
M0205882 |
CIGMFIEK_00088 |
64802 |
7 |
Gut |
0.78 |
protein_coding |
synonymous_variant |
LOW |
396G>A |
Lys132Lys |
M0205883 |
CIGMFIEK_00088 |
64826 |
7 |
Gut |
0.78 |
protein_coding |
synonymous_variant |
LOW |
420G>C |
Ser140Ser |
M0205884 |
CIGMFIEK_00088 |
64835 |
7 |
Gut |
0.78 |
protein_coding |
synonymous_variant |
LOW |
429T>C |
Arg143Arg |
M0205885 |
CIGMFIEK_00088 |
64901 |
7 |
Gut |
0.78 |
protein_coding |
synonymous_variant |
LOW |
495G>A |
Glu165Glu |
M0205886 |
CIGMFIEK_00088 |
64925 |
7 |
Gut |
0.78 |
protein_coding |
synonymous_variant |
LOW |
519C>T |
Ala173Ala |
M0205887 |
CIGMFIEK_00088 |
64937 |
7 |
Gut |
0.78 |
protein_coding |
synonymous_variant |
LOW |
531G>T |
Leu177Leu |
M0205888 |
CIGMFIEK_00088 |
64964 |
7 |
Gut |
0.78 |
protein_coding |
synonymous_variant |
LOW |
558A>G |
Lys186Lys |
M0205889 |
CIGMFIEK_00088 |
64973 |
7 |
Gut |
0.78 |
protein_coding |
synonymous_variant |
LOW |
567C>T |
Leu189Leu |
M0205890 |
CIGMFIEK_00088 |
65063 |
8 |
Gut |
0.89 |
protein_coding |
synonymous_variant |
LOW |
657G>A |
Arg219Arg |
M0205891 |
CIGMFIEK_00089 |
65242 |
7 |
Gut |
0.78 |
protein_coding |
synonymous_variant |
LOW |
102G>A |
Ala34Ala |
M0205892 |
CIGMFIEK_00089 |
65274 |
5 |
Gut |
0.56 |
protein_coding |
missense_variant |
MODERATE |
134C>T |
Pro45Leu |
M0205893 |
CIGMFIEK_00089 |
65309 |
7 |
Gut |
0.78 |
protein_coding |
missense_variant |
MODERATE |
169G>A |
Ala57Thr |
M0205894 |
CIGMFIEK_00089 |
65332 |
7 |
Gut |
0.78 |
protein_coding |
synonymous_variant |
LOW |
192G>A |
Glu64Glu |
M0205895 |
CIGMFIEK_00083 |
65628 |
8 |
Gut |
0.89 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4276G>A |
None |
M0205896 |
CIGMFIEK_00083 |
65635 |
8 |
Gut |
0.89 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4283A>C |
None |
M0205897 |
CIGMFIEK_00090 |
65669 |
7 |
Gut |
0.78 |
protein_coding |
splice_region_variant&stop_retained_variant |
LOW |
740G>A |
Ter247Ter |
M0205898 |
CIGMFIEK_00090 |
65713 |
8 |
Gut |
0.89 |
protein_coding |
synonymous_variant |
LOW |
696G>T |
Gly232Gly |
M0205899 |
CIGMFIEK_00090 |
65758 |
7 |
Gut |
0.78 |
protein_coding |
synonymous_variant |
LOW |
651G>A |
Ala217Ala |
M0205900 |
CIGMFIEK_00090 |
65767 |
7 |
Gut |
0.78 |
protein_coding |
synonymous_variant |
LOW |
642A>G |
Arg214Arg |
M0205901 |
CIGMFIEK_00090 |
65769 |
7 |
Gut |
0.78 |
protein_coding |
synonymous_variant |
LOW |
640A>C |
Arg214Arg |
M0205902 |
CIGMFIEK_00090 |
65770 |
7 |
Gut |
0.78 |
protein_coding |
synonymous_variant |
LOW |
639C>G |
Thr213Thr |
M0205903 |
CIGMFIEK_00090 |
65803 |
8 |
Gut |
0.89 |
protein_coding |
synonymous_variant |
LOW |
606G>T |
Gly202Gly |
M0205904 |
CIGMFIEK_00090 |
65806 |
8 |
Gut |
0.89 |
protein_coding |
synonymous_variant |
LOW |
603C>T |
Ala201Ala |
M0205905 |
CIGMFIEK_00090 |
65875 |
8 |
Gut |
0.89 |
protein_coding |
synonymous_variant |
LOW |
534G>C |
Thr178Thr |
M0205906 |
CIGMFIEK_00090 |
65878 |
7 |
Gut |
0.78 |
protein_coding |
synonymous_variant |
LOW |
531C>T |
His177His |
M0205907 |
CIGMFIEK_00090 |
65914 |
8 |
Gut |
0.89 |
protein_coding |
synonymous_variant |
LOW |
495A>T |
Ala165Ala |
M0205908 |
CIGMFIEK_00090 |
65962 |
8 |
Gut |
0.89 |
protein_coding |
synonymous_variant |
LOW |
447T>C |
Asp149Asp |
M0205909 |
CIGMFIEK_00090 |
66067 |
7 |
Gut |
0.78 |
protein_coding |
synonymous_variant |
LOW |
342A>G |
Glu114Glu |
M0205910 |
CIGMFIEK_00090 |
66134 |
8 |
Gut |
0.89 |
protein_coding |
missense_variant |
MODERATE |
275C>T |
Ala92Val |
M0205911 |
CIGMFIEK_00090 |
66259 |
8 |
Gut |
0.89 |
protein_coding |
synonymous_variant |
LOW |
150C>G |
Val50Val |
M0205912 |
CIGMFIEK_00090 |
66301 |
8 |
Gut |
0.89 |
protein_coding |
synonymous_variant |
LOW |
108C>T |
Thr36Thr |
M0205913 |
CIGMFIEK_00090 |
66379 |
4 |
Gut |
0.44 |
protein_coding |
synonymous_variant |
LOW |
30A>G |
Ser10Ser |
M0205914 |
CIGMFIEK_00084 |
66550 |
7 |
Gut |
0.78 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-3997T>C |
None |
M0205915 |
CIGMFIEK_00084 |
66571 |
7 |
Gut |
0.78 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4018G>A |
None |
M0205916 |
CIGMFIEK_00084 |
66572 |
7 |
Gut |
0.78 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4019T>A |
None |
M0205917 |
CIGMFIEK_00084 |
66573 |
7 |
Gut |
0.78 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4020C>T |
None |
M0205918 |
CIGMFIEK_00084 |
66600 |
8 |
Gut |
0.89 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4047C>T |
None |
M0205919 |
CIGMFIEK_00091 |
66676 |
7 |
Gut |
0.78 |
protein_coding |
missense_variant |
MODERATE |
34G>A |
Val12Ile |
M0205920 |
CIGMFIEK_00091 |
66698 |
7 |
Gut |
0.78 |
protein_coding |
missense_variant |
MODERATE |
56A>G |
Glu19Gly |
M0205921 |
CIGMFIEK_00091 |
66709 |
7 |
Gut |
0.78 |
protein_coding |
missense_variant |
MODERATE |
67G>A |
Glu23Lys |
M0205922 |
CIGMFIEK_00091 |
66750 |
8 |
Gut |
0.89 |
protein_coding |
synonymous_variant |
LOW |
108C>T |
Gly36Gly |
M0205923 |
CIGMFIEK_00091 |
66751 |
7 |
Gut |
0.78 |
protein_coding |
missense_variant |
MODERATE |
109A>G |
Thr37Ala |
M0205924 |
CIGMFIEK_00092 |
66859 |
7 |
Gut |
0.78 |
protein_coding |
synonymous_variant |
LOW |
33G>A |
Glu11Glu |
M0205925 |
CIGMFIEK_00092 |
66907 |
7 |
Gut |
0.78 |
protein_coding |
synonymous_variant |
LOW |
81A>C |
Ala27Ala |
M0205926 |
CIGMFIEK_00092 |
66916 |
7 |
Gut |
0.78 |
protein_coding |
synonymous_variant |
LOW |
90T>C |
Thr30Thr |
M0205927 |
CIGMFIEK_00092 |
66919 |
7 |
Gut |
0.78 |
protein_coding |
synonymous_variant |
LOW |
93C>A |
Ala31Ala |
M0205928 |
CIGMFIEK_00092 |
66962 |
7 |
Gut |
0.78 |
protein_coding |
missense_variant |
MODERATE |
136T>G |
Ser46Ala |
M0205929 |
CIGMFIEK_00092 |
66964 |
7 |
Gut |
0.78 |
protein_coding |
synonymous_variant |
LOW |
138A>G |
Ser46Ser |
M0205930 |
CIGMFIEK_00092 |
67013 |
7 |
Gut |
0.78 |
protein_coding |
synonymous_variant |
LOW |
187C>T |
Leu63Leu |
M0205931 |
CIGMFIEK_00092 |
67038 |
7 |
Gut |
0.78 |
protein_coding |
missense_variant |
MODERATE |
212C>A |
Thr71Asn |
M0205932 |
CIGMFIEK_00092 |
67055 |
7 |
Gut |
0.78 |
protein_coding |
missense_variant |
MODERATE |
229A>G |
Ile77Val |
M0205933 |
CIGMFIEK_00092 |
67090 |
7 |
Gut |
0.78 |
protein_coding |
synonymous_variant |
LOW |
264T>C |
Tyr88Tyr |
M0205934 |
CIGMFIEK_00092 |
67101 |
7 |
Gut |
0.78 |
protein_coding |
missense_variant |
MODERATE |
275A>C |
Lys92Thr |
M0205935 |
CIGMFIEK_00092 |
67106 |
7 |
Gut |
0.78 |
protein_coding |
missense_variant |
MODERATE |
280A>C |
Asn94His |
M0205936 |
CIGMFIEK_00092 |
67108 |
7 |
Gut |
0.78 |
protein_coding |
missense_variant |
MODERATE |
282T>A |
Asn94Lys |
M0205937 |
CIGMFIEK_00092 |
67138 |
7 |
Gut |
0.78 |
protein_coding |
synonymous_variant |
LOW |
312G>A |
Leu104Leu |
M0205938 |
CIGMFIEK_00092 |
67139 |
7 |
Gut |
0.78 |
protein_coding |
missense_variant |
MODERATE |
313G>A |
Glu105Lys |
M0205939 |
CIGMFIEK_00092 |
67141 |
7 |
Gut |
0.78 |
protein_coding |
missense_variant |
MODERATE |
315A>C |
Glu105Asp |
M0205940 |
CIGMFIEK_00092 |
67148 |
7 |
Gut |
0.78 |
protein_coding |
missense_variant |
MODERATE |
322C>G |
Pro108Ala |
M0205941 |
CIGMFIEK_00092 |
67153 |
7 |
Gut |
0.78 |
protein_coding |
synonymous_variant |
LOW |
327G>A |
Ala109Ala |
M0205942 |
CIGMFIEK_00092 |
67163 |
7 |
Gut |
0.78 |
protein_coding |
missense_variant |
MODERATE |
337A>T |
Ser113Cys |
M0205943 |
CIGMFIEK_00092 |
67164 |
7 |
Gut |
0.78 |
protein_coding |
missense_variant |
MODERATE |
338G>C |
Ser113Thr |
M0205944 |
CIGMFIEK_00092 |
67165 |
7 |
Gut |
0.78 |
protein_coding |
missense_variant |
MODERATE |
339C>G |
Ser113Arg |
M0205945 |
CIGMFIEK_00092 |
67269 |
7 |
Gut |
0.78 |
protein_coding |
missense_variant |
MODERATE |
443A>G |
Asn148Ser |
M0205946 |
CIGMFIEK_00092 |
67271 |
7 |
Gut |
0.78 |
protein_coding |
missense_variant |
MODERATE |
445A>T |
Asn149Tyr |
M0205947 |
CIGMFIEK_00092 |
67272 |
8 |
Gut |
0.89 |
protein_coding |
missense_variant |
MODERATE |
446A>C |
Asn149Thr |
M0205948 |
CIGMFIEK_00092 |
67287 |
7 |
Gut |
0.78 |
protein_coding |
missense_variant |
MODERATE |
461A>C |
Asn154Thr |
M0205949 |
CIGMFIEK_00092 |
67313 |
8 |
Gut |
0.89 |
protein_coding |
missense_variant |
MODERATE |
487A>G |
Ser163Gly |
M0205950 |
CIGMFIEK_00092 |
67326 |
7 |
Gut |
0.78 |
protein_coding |
missense_variant |
MODERATE |
500C>T |
Ser167Leu |
M0205951 |
CIGMFIEK_00093 |
67466 |
7 |
Gut |
0.78 |
protein_coding |
missense_variant |
MODERATE |
25C>A |
His9Asn |
M0205952 |
CIGMFIEK_00093 |
67468 |
7 |
Gut |
0.78 |
protein_coding |
synonymous_variant |
LOW |
27T>C |
His9His |
M0205953 |
CIGMFIEK_00093 |
67570 |
8 |
Gut |
0.89 |
protein_coding |
synonymous_variant |
LOW |
129A>G |
Gln43Gln |
M0205954 |
CIGMFIEK_00093 |
67595 |
7 |
Gut |
0.78 |
protein_coding |
missense_variant |
MODERATE |
154G>A |
Ala52Thr |
M0205955 |
CIGMFIEK_00093 |
67606 |
8 |
Gut |
0.89 |
protein_coding |
synonymous_variant |
LOW |
165C>T |
Asp55Asp |
M0205956 |
CIGMFIEK_00093 |
67617 |
7 |
Gut |
0.78 |
protein_coding |
missense_variant |
MODERATE |
176T>A |
Ile59Lys |
M0205957 |
CIGMFIEK_00093 |
67760 |
7 |
Gut |
0.78 |
protein_coding |
synonymous_variant |
LOW |
319T>C |
Leu107Leu |
M0205958 |
CIGMFIEK_00093 |
67763 |
7 |
Gut |
0.78 |
protein_coding |
synonymous_variant |
LOW |
322T>C |
Leu108Leu |
M0205959 |
CIGMFIEK_00093 |
67791 |
8 |
Gut |
0.89 |
protein_coding |
missense_variant |
MODERATE |
350T>G |
Met117Arg |
M0205960 |
CIGMFIEK_00094 |
67978 |
7 |
Gut |
0.78 |
protein_coding |
synonymous_variant |
LOW |
117T>C |
Asp39Asp |
M0205961 |
CIGMFIEK_00094 |
68003 |
8 |
Gut |
0.89 |
protein_coding |
missense_variant |
MODERATE |
142G>A |
Glu48Lys |
M0205962 |
CIGMFIEK_00094 |
68089 |
7 |
Gut |
0.78 |
protein_coding |
synonymous_variant |
LOW |
228A>G |
Glu76Glu |
M0205963 |
CIGMFIEK_00094 |
68113 |
7 |
Gut |
0.78 |
protein_coding |
synonymous_variant |
LOW |
252C>T |
Gly84Gly |
M0205964 |
CIGMFIEK_00094 |
68118 |
7 |
Gut |
0.78 |
protein_coding |
missense_variant |
MODERATE |
257G>A |
Arg86His |
M0205965 |
CIGMFIEK_00094 |
68236 |
8 |
Gut |
0.89 |
protein_coding |
synonymous_variant |
LOW |
375A>G |
Gly125Gly |
M0205966 |
CIGMFIEK_00094 |
68261 |
7 |
Gut |
0.78 |
protein_coding |
missense_variant |
MODERATE |
400G>A |
Ala134Thr |
M0205967 |
CIGMFIEK_00094 |
68269 |
8 |
Gut |
0.89 |
protein_coding |
synonymous_variant |
LOW |
408A>G |
Ala136Ala |
M0205968 |
CIGMFIEK_00094 |
68321 |
8 |
Gut |
0.89 |
protein_coding |
missense_variant |
MODERATE |
460A>C |
Ile154Leu |
M0205969 |
CIGMFIEK_00094 |
68331 |
8 |
Gut |
0.89 |
protein_coding |
missense_variant |
MODERATE |
470G>A |
Gly157Glu |
M0205970 |
CIGMFIEK_00094 |
68347 |
8 |
Gut |
0.89 |
protein_coding |
synonymous_variant |
LOW |
486C>T |
His162His |
M0205971 |
CIGMFIEK_00094 |
68448 |
7 |
Gut |
0.78 |
protein_coding |
missense_variant |
MODERATE |
587T>C |
Val196Ala |
M0205972 |
CIGMFIEK_00094 |
68539 |
8 |
Gut |
0.89 |
protein_coding |
synonymous_variant |
LOW |
678C>T |
Asn226Asn |
M0205973 |
CIGMFIEK_00094 |
68551 |
7 |
Gut |
0.78 |
protein_coding |
synonymous_variant |
LOW |
690C>A |
Gly230Gly |
M0205974 |
CIGMFIEK_00094 |
68560 |
7 |
Gut |
0.78 |
protein_coding |
synonymous_variant |
LOW |
699C>A |
Gly233Gly |
M0205975 |
CIGMFIEK_00094 |
68833 |
7 |
Gut |
0.78 |
protein_coding |
synonymous_variant |
LOW |
972C>T |
Asp324Asp |
M0205976 |
CIGMFIEK_00094 |
69450 |
8 |
Gut |
0.89 |
protein_coding |
missense_variant |
MODERATE |
1589A>G |
Asn530Ser |
M0205977 |
CIGMFIEK_00095 |
69897 |
7 |
Gut |
0.78 |
protein_coding |
synonymous_variant |
LOW |
381A>G |
Val127Val |
M0205978 |
CIGMFIEK_00095 |
70011 |
7 |
Gut |
0.78 |
protein_coding |
synonymous_variant |
LOW |
495C>T |
Gly165Gly |
M0205979 |
CIGMFIEK_00095 |
70114 |
7 |
Gut |
0.78 |
protein_coding |
missense_variant |
MODERATE |
598A>G |
Asn200Asp |
M0205980 |
CIGMFIEK_00095 |
70355 |
7 |
Gut |
0.78 |
protein_coding |
missense_variant |
MODERATE |
839G>T |
Gly280Val |
M0205981 |
CIGMFIEK_00095 |
70455 |
8 |
Gut |
0.89 |
protein_coding |
synonymous_variant |
LOW |
939A>G |
Ser313Ser |
M0205982 |
CIGMFIEK_00095 |
70488 |
8 |
Gut |
0.89 |
protein_coding |
synonymous_variant |
LOW |
972G>A |
Gln324Gln |
M0205983 |
CIGMFIEK_00095 |
70603 |
7 |
Gut |
0.78 |
protein_coding |
missense_variant |
MODERATE |
1087A>C |
Asn363His |
M0205984 |
CIGMFIEK_00095 |
70791 |
7 |
Gut |
0.78 |
protein_coding |
synonymous_variant |
LOW |
1275A>G |
Thr425Thr |
M0205985 |
CIGMFIEK_00095 |
71079 |
6 |
Gut |
0.67 |
protein_coding |
synonymous_variant |
LOW |
1563C>T |
Val521Val |
M0205986 |
CIGMFIEK_00095 |
71137 |
7 |
Gut |
0.78 |
protein_coding |
missense_variant |
MODERATE |
1621A>G |
Met541Val |
M0205987 |
CIGMFIEK_00095 |
71158 |
6 |
Gut |
0.67 |
protein_coding |
missense_variant |
MODERATE |
1642G>A |
Asp548Asn |
M0205988 |
CIGMFIEK_00096 |
71368 |
6 |
Gut |
0.67 |
protein_coding |
synonymous_variant |
LOW |
108C>T |
His36His |
M0205989 |
CIGMFIEK_00096 |
71513 |
7 |
Gut |
0.78 |
protein_coding |
synonymous_variant |
LOW |
253T>C |
Leu85Leu |
M0205990 |
CIGMFIEK_00096 |
71752 |
6 |
Gut |
0.67 |
protein_coding |
synonymous_variant |
LOW |
492C>T |
Arg164Arg |
M0205991 |
CIGMFIEK_00096 |
71953 |
6 |
Gut |
0.67 |
protein_coding |
synonymous_variant |
LOW |
693C>T |
Asn231Asn |
M0205992 |
CIGMFIEK_00096 |
72043 |
6 |
Gut |
0.67 |
protein_coding |
synonymous_variant |
LOW |
783G>A |
Glu261Glu |
M0205993 |
CIGMFIEK_00096 |
72310 |
6 |
Gut |
0.67 |
protein_coding |
synonymous_variant |
LOW |
1050C>T |
Ala350Ala |
M0205994 |
CIGMFIEK_00096 |
72405 |
6 |
Gut |
0.67 |
protein_coding |
missense_variant |
MODERATE |
1145G>A |
Arg382Lys |
M0205995 |
CIGMFIEK_00096 |
72413 |
7 |
Gut |
0.78 |
protein_coding |
missense_variant |
MODERATE |
1153A>G |
Asn385Asp |
M0205996 |
CIGMFIEK_00096 |
72414 |
6 |
Gut |
0.67 |
protein_coding |
missense_variant |
MODERATE |
1154A>C |
Asn385Thr |
M0205997 |
CIGMFIEK_00097 |
73081 |
7 |
Gut |
0.78 |
protein_coding |
synonymous_variant |
LOW |
267T>C |
Ala89Ala |
M0205998 |
CIGMFIEK_00097 |
73183 |
6 |
Gut |
0.67 |
protein_coding |
synonymous_variant |
LOW |
369A>T |
Pro123Pro |
M0205999 |
CIGMFIEK_00097 |
73382 |
3 |
Gut |
0.33 |
protein_coding |
synonymous_variant |
LOW |
568C>T |
Leu190Leu |
M0206000 |
CIGMFIEK_00098 |
73890 |
6 |
Gut |
0.67 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-5G>A |
None |
M0206001 |
CIGMFIEK_00098 |
73901 |
6 |
Gut |
0.67 |
protein_coding |
missense_variant |
MODERATE |
7A>G |
Ile3Val |
M0206002 |
CIGMFIEK_00098 |
74839 |
3 |
Gut |
0.33 |
protein_coding |
missense_variant |
MODERATE |
945C>A |
Asn315Lys |
M0206003 |
CIGMFIEK_00099 |
74941 |
6 |
Gut |
0.67 |
protein_coding |
synonymous_variant |
LOW |
84G>T |
Leu28Leu |
M0206004 |
CIGMFIEK_00099 |
75350 |
6 |
Gut |
0.67 |
protein_coding |
missense_variant |
MODERATE |
493G>A |
Ala165Thr |
M0206005 |
CIGMFIEK_00099 |
75493 |
7 |
Gut |
0.78 |
protein_coding |
synonymous_variant |
LOW |
636A>G |
Leu212Leu |
M0206006 |
CIGMFIEK_00100 |
75687 |
7 |
Gut |
0.78 |
protein_coding |
synonymous_variant |
LOW |
99G>T |
Thr33Thr |
M0206007 |
CIGMFIEK_00100 |
75993 |
7 |
Gut |
0.78 |
protein_coding |
synonymous_variant |
LOW |
405G>T |
Gly135Gly |
M0206008 |
CIGMFIEK_00101 |
76044 |
6 |
Gut |
0.67 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-12C>T |
None |
M0206009 |
CIGMFIEK_00101 |
76199 |
7 |
Gut |
0.78 |
protein_coding |
synonymous_variant |
LOW |
144G>A |
Ala48Ala |
M0206010 |
CIGMFIEK_00101 |
76359 |
7 |
Gut |
0.78 |
protein_coding |
missense_variant |
MODERATE |
304C>T |
His102Tyr |
M0206011 |
CIGMFIEK_00101 |
76394 |
6 |
Gut |
0.67 |
protein_coding |
synonymous_variant |
LOW |
339G>A |
Gly113Gly |
M0206012 |
CIGMFIEK_00101 |
76540 |
6 |
Gut |
0.67 |
protein_coding |
missense_variant |
MODERATE |
485C>T |
Ser162Leu |
M0206013 |
CIGMFIEK_00102 |
76705 |
7 |
Gut |
0.78 |
protein_coding |
synonymous_variant |
LOW |
108G>A |
Glu36Glu |
M0206014 |
CIGMFIEK_00103 |
77189 |
6 |
Gut |
0.67 |
protein_coding |
synonymous_variant |
LOW |
51A>G |
Ala17Ala |
M0206015 |
CIGMFIEK_00103 |
77228 |
7 |
Gut |
0.78 |
protein_coding |
synonymous_variant |
LOW |
90T>G |
Gly30Gly |
M0206016 |
CIGMFIEK_00103 |
77279 |
7 |
Gut |
0.78 |
protein_coding |
synonymous_variant |
LOW |
141C>A |
Ala47Ala |
M0206017 |
CIGMFIEK_00103 |
77350 |
6 |
Gut |
0.67 |
protein_coding |
missense_variant |
MODERATE |
212C>T |
Ala71Val |
M0206018 |
CIGMFIEK_00103 |
77431 |
7 |
Gut |
0.78 |
protein_coding |
missense_variant |
MODERATE |
293A>G |
Asn98Ser |
M0206019 |
CIGMFIEK_00104 |
77702 |
7 |
Gut |
0.78 |
protein_coding |
missense_variant |
MODERATE |
73T>C |
Cys25Arg |
M0206020 |
CIGMFIEK_00104 |
77764 |
6 |
Gut |
0.67 |
protein_coding |
synonymous_variant |
LOW |
135A>T |
Thr45Thr |
M0206021 |
CIGMFIEK_00104 |
77807 |
7 |
Gut |
0.78 |
protein_coding |
missense_variant |
MODERATE |
178A>G |
Ser60Gly |
M0206022 |
CIGMFIEK_00105 |
78180 |
6 |
Gut |
0.67 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-187G>A |
None |
M0206023 |
CIGMFIEK_00105 |
78191 |
6 |
Gut |
0.67 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-176A>C |
None |
M0206024 |
CIGMFIEK_00105 |
78297 |
6 |
Gut |
0.67 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-70A>G |
None |
M0206025 |
CIGMFIEK_00105 |
78528 |
6 |
Gut |
0.67 |
protein_coding |
synonymous_variant |
LOW |
162C>T |
Ser54Ser |
M0206026 |
CIGMFIEK_00105 |
78615 |
6 |
Gut |
0.67 |
protein_coding |
synonymous_variant |
LOW |
249G>T |
Gly83Gly |
M0206027 |
CIGMFIEK_00091 |
66784 |
3 |
Gut |
0.33 |
protein_coding |
missense_variant |
MODERATE |
142C>T |
Arg48Cys |
M0206028 |
CIGMFIEK_00092 |
67278 |
3 |
Gut |
0.33 |
protein_coding |
missense_variant |
MODERATE |
452C>A |
Ala151Asp |
M0206029 |
CIGMFIEK_00095 |
69780 |
3 |
Gut |
0.33 |
protein_coding |
synonymous_variant |
LOW |
264G>A |
Leu88Leu |
M0206030 |
CIGMFIEK_00095 |
70329 |
3 |
Gut |
0.33 |
protein_coding |
synonymous_variant |
LOW |
813A>G |
Gly271Gly |
M0206031 |
CIGMFIEK_00096 |
72010 |
3 |
Gut |
0.33 |
protein_coding |
synonymous_variant |
LOW |
750C>T |
Thr250Thr |
M0206032 |
CIGMFIEK_00102 |
76979 |
3 |
Gut |
0.33 |
protein_coding |
missense_variant |
MODERATE |
382A>G |
Ile128Val |
Analysis of virulence factors contributing to bacterial pathogenicity
This table presents virulence factors identified within the plasmid cluster.
Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.
Gene Name |
vf_gene_id |
vf_name |
identity |
evalue |
qstart |
qend |
query_coverage |
subject_coverage |
vf_category |
gene_description |
condition |
CIGMFIEK_00092 |
VFG042784 |
BFP |
85.6 |
3.4e-80 |
1 |
193 |
1.0 |
1 |
Adherence |
major pilin structural unit bundlin |
experiment |
CIGMFIEK_00093 |
VFG000750 |
BFP |
96.1 |
8.1e-68 |
11 |
137 |
0.927 |
0.9549 |
Adherence |
BFP biogenesis protein BfpG |
experiment |
CIGMFIEK_00094 |
VFG000751 |
BFP |
98.7 |
1.5e-298 |
1 |
552 |
1.0 |
1 |
Adherence |
BfpB secretin |
experiment |
CIGMFIEK_00095 |
VFG000752 |
BFP |
99.5 |
1.6e-239 |
1 |
400 |
0.7156 |
0.995 |
Adherence |
BfpC, bitopic inner membrane protein |
experiment |
CIGMFIEK_00096 |
VFG042789 |
BFP |
99.4 |
6.8e-293 |
10 |
515 |
0.9825 |
0.9458 |
Adherence |
assembly ATPase |
experiment |
CIGMFIEK_00097 |
VFG000755 |
BFP |
100 |
3.3e-198 |
1 |
352 |
1.0 |
1 |
Adherence |
BfpE, polytopic inner membrane protein |
experiment |
CIGMFIEK_00098 |
VFG042791 |
BFP |
99.7 |
9.1e-179 |
1 |
318 |
1.0 |
0.9607 |
Adherence |
retraction ATPase |
experiment |
CIGMFIEK_00099 |
VFG000757 |
BFP |
99.2 |
5.7e-144 |
1 |
249 |
1.0 |
1 |
Adherence |
prepilin peptidase BfpP |
experiment |
CIGMFIEK_00100 |
VFG042793 |
BFP |
98.6 |
1.6e-82 |
1 |
148 |
1.0 |
1 |
Adherence |
lipoprotein |
experiment |
CIGMFIEK_00101 |
VFG042794 |
BFP |
98.3 |
2.5e-96 |
1 |
181 |
1.0 |
1 |
Adherence |
minor pilin subunit BfpI |
experiment |
CIGMFIEK_00102 |
VFG000760 |
BFP |
100 |
8.8e-102 |
1 |
183 |
1.0 |
1 |
Adherence |
minor pilin subunit BfpJ |
experiment |
CIGMFIEK_00103 |
VFG042796 |
BFP |
98.8 |
1.6e-86 |
1 |
162 |
1.0 |
1 |
Adherence |
minor pilin subunit BfpK |
experiment |
CIGMFIEK_00104 |
VFG000762 |
BFP |
98.7 |
4.5e-80 |
1 |
149 |
1.0 |
1 |
Adherence |
BFP biogenesis protein BfpL |
experiment |
CIGMFIEK_00126 |
VFG042219 |
TTSS secreted effectors |
83.3 |
6.2e-63 |
1 |
132 |
0.9429 |
0.7213 |
Effector delivery system |
Type III secretion system effector EspT, Rho guanine exchange factor |
experiment |
CIGMFIEK_00144 |
VFG000764 |
Per |
95.3 |
4.1e-69 |
1 |
129 |
1.0 |
1 |
Regulation |
BfpV |
experiment |
CIGMFIEK_00145 |
VFG000765 |
Per |
98.9 |
2.2e-45 |
1 |
89 |
1.0 |
1 |
Regulation |
BfpW |
experiment |
CIGMFIEK_00092 |
VFG042784 |
BFP |
85.6 |
2.6e-79 |
1 |
193 |
1.0 |
1 |
Adherence |
major pilin structural unit bundlin |
prediction |
CIGMFIEK_00093 |
VFG000750 |
BFP |
96.1 |
6.1e-67 |
11 |
137 |
0.927 |
0.9549 |
Adherence |
BFP biogenesis protein BfpG |
prediction |
CIGMFIEK_00094 |
VFG000751 |
BFP |
98.7 |
1.1e-297 |
1 |
552 |
1.0 |
1 |
Adherence |
BfpB secretin |
prediction |
CIGMFIEK_00095 |
VFG000752 |
BFP |
99.5 |
1.2e-238 |
1 |
400 |
0.7156 |
0.995 |
Adherence |
BfpC, bitopic inner membrane protein |
prediction |
CIGMFIEK_00096 |
VFG042789 |
BFP |
99.4 |
5.1e-292 |
10 |
515 |
0.9825 |
0.9458 |
Adherence |
assembly ATPase |
prediction |
CIGMFIEK_00097 |
VFG000755 |
BFP |
100 |
2.5e-197 |
1 |
352 |
1.0 |
1 |
Adherence |
BfpE, polytopic inner membrane protein |
prediction |
CIGMFIEK_00098 |
VFG042791 |
BFP |
99.7 |
6.8e-178 |
1 |
318 |
1.0 |
0.9607 |
Adherence |
retraction ATPase |
prediction |
CIGMFIEK_00099 |
VFG000757 |
BFP |
99.2 |
4.2e-143 |
1 |
249 |
1.0 |
1 |
Adherence |
prepilin peptidase BfpP |
prediction |
CIGMFIEK_00100 |
VFG042793 |
BFP |
98.6 |
1.2e-81 |
1 |
148 |
1.0 |
1 |
Adherence |
lipoprotein |
prediction |
CIGMFIEK_00101 |
VFG042794 |
BFP |
98.3 |
1.8e-95 |
1 |
181 |
1.0 |
1 |
Adherence |
minor pilin subunit BfpI |
prediction |
CIGMFIEK_00102 |
VFG000760 |
BFP |
100 |
6.6e-101 |
1 |
183 |
1.0 |
1 |
Adherence |
minor pilin subunit BfpJ |
prediction |
CIGMFIEK_00103 |
VFG042796 |
BFP |
98.8 |
1.2e-85 |
1 |
162 |
1.0 |
1 |
Adherence |
minor pilin subunit BfpK |
prediction |
CIGMFIEK_00104 |
VFG000762 |
BFP |
98.7 |
3.4e-79 |
1 |
149 |
1.0 |
1 |
Adherence |
BFP biogenesis protein BfpL |
prediction |
CIGMFIEK_00113 |
VFG041523 |
T3SS |
79.8 |
2.7e-98 |
1 |
213 |
1.0 |
1 |
Effector delivery system |
T3SS effector NleG family protein |
prediction |
CIGMFIEK_00126 |
VFG042219 |
TTSS secreted effectors |
83.3 |
4.6e-62 |
1 |
132 |
0.9429 |
0.7213 |
Effector delivery system |
Type III secretion system effector EspT, Rho guanine exchange factor |
prediction |
CIGMFIEK_00144 |
VFG000764 |
Per |
95.3 |
3e-68 |
1 |
129 |
1.0 |
1 |
Regulation |
BfpV |
prediction |
CIGMFIEK_00145 |
VFG000765 |
Per |
98.9 |
1.6e-44 |
1 |
89 |
1.0 |
1 |
Regulation |
BfpW |
prediction |
Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact
This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.
Gene Name |
compound |
identity |
evalue |
qstart |
qend |
query_coverage |
subject_coverage |
group |
Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents
This table presents antimicrobial resistance genes identified within the plasmid cluster.
Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.
Gene Name |
aro_accession |
identity |
evalue |
qstart |
qend |
query_coverage |
subject_coverage |
drug_class |
amr_gene_family |
resistance_mechanism |
Analysis of pathogenicity genes to explore pathogen-host interactions
This table presents host pathogen-host interactions within the plasmid cluster.
Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.
Gene Name |
phi_molconn_id |
host gene_name |
identity |
evalue |
qstart |
qend |
query_coverage |
subject_coverage |
host_descripton |
disease_name |
function |
phenotype_of_mutant |
CIGMFIEK_00142 |
PHI:3803 |
PerA |
95.4 |
4e-54 |
1 |
108 |
0.9153 |
0.9708 |
nematodes |
hemorrhagic colitis; hemolytic uremic syndrome |
LPS O-side chain |
reduced virulence |
CIGMFIEK_00143 |
PHI:3803 |
PerA |
95.6 |
5.7e-80 |
1 |
158 |
1.0000 |
0.9708 |
nematodes |
hemorrhagic colitis; hemolytic uremic syndrome |
LPS O-side chain |
reduced virulence |
Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation
This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.
Gene Name |
cazy_id |
identity |
evalue |
qstart |
qend |
query_coverage |
subject_coverage |
CIGMFIEK_00053 |
AVL11885.1|GH23 |
99 |
5.8e-145 |
1 |
200 |
1 |
1 |
CIGMFIEK_00100 |
BAU62016.1|GH23 |
99.3 |
9.28e-103 |
1 |
148 |
1 |
1 |
Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification
This table presents transport proteins within the plasmid cluster.
Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.
Gene Name |
tcid |
identity |
evalue |
qstart |
qend |
query_coverage |
subject_coverage |
class_field |
class_term |
subclass |
subclass_term |
family |
family_term |
CIGMFIEK_00094 |
1.B.22.7.1 |
98.7 |
9e-298 |
1 |
552 |
1.0000 |
1.0000 |
1 |
Channels/Pores |
1.B |
β-Barrel Porins |
1.B.22 |
The Outer Bacterial Membrane Secretin (Secretin) Family |