Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1311
  Reference Plasmid   NZ_CP151374.1
  Reference Plasmid Size   86553
  Reference Plasmid GC Content   0.50
  Reference Plasmid Mobility Type   conjugative





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0206281 BFBKBJDN_00027 20338 3 Gut 0.60 protein_coding missense_variant MODERATE 22C>T Leu8Phe
M0206282 BFBKBJDN_00027 20370 3 Gut 0.60 protein_coding synonymous_variant LOW 54T>C Arg18Arg
M0206283 BFBKBJDN_00028 20569 3 Gut 0.60 protein_coding upstream_gene_variant MODIFIER -40G>A None
M0206284 BFBKBJDN_00028 20682 3 Gut 0.60 protein_coding missense_variant MODERATE 74T>C Val25Ala
M0206285 BFBKBJDN_00028 20683 3 Gut 0.60 protein_coding synonymous_variant LOW 75C>A Val25Val
M0206286 BFBKBJDN_00028 20723 3 Gut 0.60 protein_coding missense_variant MODERATE 115C>T Pro39Ser
M0206287 BFBKBJDN_00028 20734 3 Gut 0.60 protein_coding synonymous_variant LOW 126G>A Ser42Ser
M0206288 BFBKBJDN_00028 20800 3 Gut 0.60 protein_coding synonymous_variant LOW 192G>T Ala64Ala
M0206289 BFBKBJDN_00028 20811 3 Gut 0.60 protein_coding missense_variant MODERATE 203A>G Lys68Arg
M0206290 BFBKBJDN_00028 20818 3 Gut 0.60 protein_coding synonymous_variant LOW 210C>T Val70Val
M0206291 BFBKBJDN_00028 20821 3 Gut 0.60 protein_coding synonymous_variant LOW 213A>C Gly71Gly
M0206292 BFBKBJDN_00028 20956 3 Gut 0.60 protein_coding synonymous_variant LOW 348G>A Lys116Lys
M0206293 BFBKBJDN_00028 20957 3 Gut 0.60 protein_coding missense_variant MODERATE 349G>A Val117Ile
M0206294 BFBKBJDN_00028 21052 3 Gut 0.60 protein_coding synonymous_variant LOW 444G>A Ala148Ala
M0206295 BFBKBJDN_00029 22639 3 Gut 0.60 protein_coding synonymous_variant LOW 18C>A Thr6Thr
M0206296 BFBKBJDN_00031 23792 3 Gut 0.60 protein_coding synonymous_variant LOW 24C>T Tyr8Tyr






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant
BFBKBJDN_00017 PHI:3113 stbA 98.2 3.7e-182 1 326 1.0000 1.0000 rodents neonatal meningitis stability protein for the plasmid reduced virulence






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
BFBKBJDN_00081 AHF22950.1|GH23 100 5.89e-138 1 186 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
BFBKBJDN_00044 3.A.7.10.1 99.9 0 1 763 1.0000 7.9479 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.7 The Type IV (Conjugal DNA-Protein Transfer or VirB) Secretory Pathway (IVSP) Family
BFBKBJDN_00045 3.A.7.10.1 98 5.7e-205 1 356 1.0000 3.7083 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.7 The Type IV (Conjugal DNA-Protein Transfer or VirB) Secretory Pathway (IVSP) Family
BFBKBJDN_00046 3.A.7.10.1 99.3 7.8e-243 1 402 1.0000 4.1875 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.7 The Type IV (Conjugal DNA-Protein Transfer or VirB) Secretory Pathway (IVSP) Family
BFBKBJDN_00054 9.B.40.1.2 97.6 0 1 722 1.0000 0.9691 9 Incompletely Characterized Transport Systems 9.B Putative transport proteins 9.B.40 The DotA/TraY (DotA/TraY) Family
BFBKBJDN_00065 3.A.7.10.1 99.7 1.4e-184 1 327 1.0000 3.4063 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.7 The Type IV (Conjugal DNA-Protein Transfer or VirB) Secretory Pathway (IVSP) Family
BFBKBJDN_00066 3.A.7.10.1 99.1 7.4e-129 1 230 1.0000 2.3958 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.7 The Type IV (Conjugal DNA-Protein Transfer or VirB) Secretory Pathway (IVSP) Family
BFBKBJDN_00067 3.A.7.10.1 100 1.3e-57 1 115 1.0000 1.1979 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.7 The Type IV (Conjugal DNA-Protein Transfer or VirB) Secretory Pathway (IVSP) Family
BFBKBJDN_00070 3.A.7.10.1 97.9 1.3e-55 1 96 1.0000 1.0000 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.7 The Type IV (Conjugal DNA-Protein Transfer or VirB) Secretory Pathway (IVSP) Family
BFBKBJDN_00071 3.A.7.10.1 100 3.3e-222 1 382 1.0000 3.9792 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.7 The Type IV (Conjugal DNA-Protein Transfer or VirB) Secretory Pathway (IVSP) Family
BFBKBJDN_00072 3.A.7.10.1 98.5 3.1e-158 1 272 1.0000 2.8333 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.7 The Type IV (Conjugal DNA-Protein Transfer or VirB) Secretory Pathway (IVSP) Family
BFBKBJDN_00073 3.A.7.10.1 99.3 2.3e-86 1 152 1.0000 1.5833 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.7 The Type IV (Conjugal DNA-Protein Transfer or VirB) Secretory Pathway (IVSP) Family