Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1318
  Reference Plasmid   NZ_EU818711.1
  Reference Plasmid Size   8944
  Reference Plasmid GC Content   0.44
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0206334 LBHENBFG_00001 2918 3 Gut 0.30 protein_coding upstream_gene_variant MODIFIER -2439A>G None
M0206335 LBHENBFG_00007 3628 4 Gut 0.40 protein_coding missense_variant MODERATE 22A>G Ser8Gly
M0206336 LBHENBFG_00007 3663 4 Gut 0.40 protein_coding synonymous_variant LOW 57T>C Cys19Cys
M0206337 LBHENBFG_00007 3732 4 Gut 0.40 protein_coding synonymous_variant LOW 126G>A Pro42Pro
M0206338 LBHENBFG_00007 3877 4 Gut 0.40 protein_coding missense_variant MODERATE 271A>G Arg91Gly
M0206339 LBHENBFG_00007 3892 4 Gut 0.40 protein_coding missense_variant MODERATE 286T>C Cys96Arg
M0206340 LBHENBFG_00007 3921 4 Gut 0.40 protein_coding synonymous_variant LOW 315G>A Arg105Arg
M0206341 LBHENBFG_00007 3968 4 Gut 0.40 protein_coding missense_variant MODERATE 362A>G Lys121Arg
M0206342 LBHENBFG_00007 3990 4 Gut 0.40 protein_coding synonymous_variant LOW 384T>C Tyr128Tyr
M0206343 LBHENBFG_00007 4002 4 Gut 0.40 protein_coding synonymous_variant LOW 396T>C His132His
M0206344 LBHENBFG_00007 4020 4 Gut 0.40 protein_coding missense_variant MODERATE 414A>C Glu138Asp
M0206345 LBHENBFG_00007 4029 4 Gut 0.40 protein_coding synonymous_variant LOW 423C>T Ser141Ser
M0206346 LBHENBFG_00007 4110 4 Gut 0.40 protein_coding synonymous_variant LOW 504G>A Gly168Gly
M0206347 LBHENBFG_00007 4138 4 Gut 0.40 protein_coding missense_variant MODERATE 532G>A Gly178Ser
M0206348 LBHENBFG_00007 4191 4 Gut 0.40 protein_coding synonymous_variant LOW 585C>A Arg195Arg
M0206349 LBHENBFG_00004 2162 5 Gut 0.50 protein_coding synonymous_variant LOW 99T>C Asn33Asn
M0206350 LBHENBFG_00006 3064 4 Gut 0.40 protein_coding synonymous_variant LOW 60T>C Asp20Asp
M0206351 LBHENBFG_00004 2039 3 Gut 0.30 protein_coding synonymous_variant LOW 222T>C Asn74Asn
M0206352 LBHENBFG_00004 2072 3 Gut 0.30 protein_coding synonymous_variant LOW 189G>T Arg63Arg
M0206353 LBHENBFG_00004 2075 3 Gut 0.30 protein_coding synonymous_variant LOW 186A>G Gln62Gln
M0206354 LBHENBFG_00004 2099 3 Gut 0.30 protein_coding synonymous_variant LOW 162A>G Glu54Glu
M0206355 LBHENBFG_00001 2982 3 Gut 0.30 protein_coding upstream_gene_variant MODIFIER -2503T>C None
M0206356 LBHENBFG_00001 2983 3 Gut 0.30 protein_coding upstream_gene_variant MODIFIER -2504G>A None
M0206357 LBHENBFG_00001 2995 3 Gut 0.30 protein_coding upstream_gene_variant MODIFIER -2516G>A None
M0206358 LBHENBFG_00006 3019 3 Gut 0.30 protein_coding synonymous_variant LOW 15C>A Thr5Thr
M0206359 LBHENBFG_00006 3025 3 Gut 0.30 protein_coding synonymous_variant LOW 21T>C Thr7Thr
M0206360 LBHENBFG_00006 3028 3 Gut 0.30 protein_coding synonymous_variant LOW 24T>G Ser8Ser
M0206361 LBHENBFG_00006 3031 3 Gut 0.30 protein_coding synonymous_variant LOW 27C>A Val9Val
M0206362 LBHENBFG_00006 3043 3 Gut 0.30 protein_coding synonymous_variant LOW 39A>G Arg13Arg
M0206363 LBHENBFG_00006 3100 3 Gut 0.30 protein_coding missense_variant MODERATE 96G>C Glu32Asp
M0206364 LBHENBFG_00006 3145 3 Gut 0.30 protein_coding synonymous_variant LOW 141C>T Asn47Asn
M0206365 LBHENBFG_00006 3160 3 Gut 0.30 protein_coding synonymous_variant LOW 156G>A Glu52Glu
M0206366 LBHENBFG_00006 3163 3 Gut 0.30 protein_coding synonymous_variant LOW 159T>C Ser53Ser
M0206367 LBHENBFG_00006 3277 3 Gut 0.30 protein_coding synonymous_variant LOW 273T>C Ser91Ser
M0206368 LBHENBFG_00006 3283 3 Gut 0.30 protein_coding synonymous_variant LOW 279G>A Arg93Arg
M0206369 LBHENBFG_00006 3581 3 Gut 0.30 protein_coding missense_variant MODERATE 577A>G Asn193Asp






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term