Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1319
  Reference Plasmid   NZ_HG813245.1
  Reference Plasmid Size   33094
  Reference Plasmid GC Content   0.28
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0116169 IIAEJOHK_00002 3832 3 Skin 0.09 protein_coding upstream_gene_variant MODIFIER -1773A>G None
M0116170 IIAEJOHK_00002 3868 3 Skin 0.09 protein_coding upstream_gene_variant MODIFIER -1809A>G None
M0116171 IIAEJOHK_00002 3922 3 Skin 0.09 protein_coding upstream_gene_variant MODIFIER -1863A>G None
M0116172 IIAEJOHK_00002 3926 3 Skin 0.09 protein_coding upstream_gene_variant MODIFIER -1867G>A None
M0116173 IIAEJOHK_00002 3927 3 Skin 0.09 protein_coding upstream_gene_variant MODIFIER -1868A>G None
M0116174 IIAEJOHK_00002 3940 3 Skin 0.09 protein_coding upstream_gene_variant MODIFIER -1881T>C None
M0116175 IIAEJOHK_00002 4180 4 Skin 0.12 protein_coding upstream_gene_variant MODIFIER -2121C>T None
M0116176 IIAEJOHK_00005 4474 4 Skin 0.12 protein_coding missense_variant MODERATE 196G>A Val66Ile
M0116177 IIAEJOHK_00005 4625 5 Skin 0.15 protein_coding missense_variant MODERATE 347A>G Asn116Ser
M0116178 IIAEJOHK_00005 4783 5 Skin 0.15 protein_coding missense_variant MODERATE 505A>G Ile169Val
M0116179 IIAEJOHK_00002 4872 5 Skin 0.15 protein_coding upstream_gene_variant MODIFIER -2813G>A None
M0116180 IIAEJOHK_00002 4874 5 Skin 0.15 protein_coding upstream_gene_variant MODIFIER -2815T>C None
M0116181 IIAEJOHK_00002 4890 5 Skin 0.15 protein_coding upstream_gene_variant MODIFIER -2831C>T None
M0116182 IIAEJOHK_00002 4892 5 Skin 0.15 protein_coding upstream_gene_variant MODIFIER -2833A>C None
M0116183 IIAEJOHK_00002 4909 3 Skin 0.09 protein_coding upstream_gene_variant MODIFIER -2850T>C None
M0116184 IIAEJOHK_00002 2516 3 Skin 0.09 protein_coding upstream_gene_variant MODIFIER -457A>G None
M0116185 IIAEJOHK_00003 2775 4 Skin 0.12 protein_coding synonymous_variant LOW 216G>A Lys72Lys
M0116186 IIAEJOHK_00004 3558 3 Skin 0.09 protein_coding missense_variant MODERATE 433C>A Gln145Lys
M0116187 IIAEJOHK_00006 9920 3 Skin 0.09 protein_coding upstream_gene_variant MODIFIER -3922T>G None
M0116188 IIAEJOHK_00011 10140 4 Skin 0.12 protein_coding missense_variant MODERATE 94T>C Ser32Pro
M0116189 IIAEJOHK_00006 10239 4 Skin 0.12 protein_coding upstream_gene_variant MODIFIER -4241C>A None
M0116190 IIAEJOHK_00006 8650 3 Skin 0.09 protein_coding upstream_gene_variant MODIFIER -2652A>C None
M0116191 IIAEJOHK_00002 4249 3 Skin 0.09 protein_coding upstream_gene_variant MODIFIER -2190T>C None
M0116192 IIAEJOHK_00023 22464 3 Skin 0.09 protein_coding upstream_gene_variant MODIFIER -4274T>C None
M0116193 IIAEJOHK_00032 24435 3 Skin 0.09 protein_coding missense_variant MODERATE 946A>G Lys316Glu
M0116194 IIAEJOHK_00032 24626 3 Skin 0.09 protein_coding missense_variant MODERATE 755T>C Ile252Thr
M0116195 IIAEJOHK_00035 26619 3 Skin 0.09 protein_coding synonymous_variant LOW 486A>G Glu162Glu
M0116196 IIAEJOHK_00005 4839 3 Skin 0.09 protein_coding missense_variant MODERATE 561G>T Lys187Asn
M0116197 IIAEJOHK_00023 18044 3 Skin 0.09 protein_coding missense_variant MODERATE 147C>A Ser49Arg
M0116198 IIAEJOHK_00003 2760 3 Skin 0.09 protein_coding synonymous_variant LOW 201T>C Tyr67Tyr
M0116199 IIAEJOHK_00003 2818 3 Skin 0.09 protein_coding missense_variant MODERATE 259G>A Glu87Lys
M0116200 IIAEJOHK_00003 2907 3 Skin 0.09 protein_coding synonymous_variant LOW 348A>G Ala116Ala
M0116201 IIAEJOHK_00003 2953 3 Skin 0.09 protein_coding missense_variant MODERATE 394A>G Ile132Val
M0116202 IIAEJOHK_00003 2982 3 Skin 0.09 protein_coding synonymous_variant LOW 423G>C Thr141Thr
M0116203 IIAEJOHK_00022 20663 3 Skin 0.09 protein_coding upstream_gene_variant MODIFIER -3510A>G None
M0116204 IIAEJOHK_00028 21445 3 Skin 0.09 protein_coding missense_variant MODERATE 391A>C Lys131Gln






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant
IIAEJOHK_00022 PHI:11807 ohyA 73.4 6.5e-62 1 143 0.9728 0.8020 rodents skin infection; food poisoning; respiratory disease oleate hydratase reduced virulence
IIAEJOHK_00023 PHI:11807 ohyA 76.4 3.1e-152 1 331 0.9940 0.8020 rodents skin infection; food poisoning; respiratory disease oleate hydratase reduced virulence
KCCKALFP_00022 PHI:11807 ohyA 73.4 6.5e-62 1 143 0.9728 0.8020 rodents skin infection; food poisoning; respiratory disease oleate hydratase reduced virulence
KCCKALFP_00023 PHI:11807 ohyA 76.4 3.1e-152 1 331 0.9940 0.8020 rodents skin infection; food poisoning; respiratory disease oleate hydratase reduced virulence






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term