Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1326
  Reference Plasmid   NZ_KP691637.1
  Reference Plasmid Size   7050
  Reference Plasmid GC Content   0.61
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0206497 AILACKOI_00008 6075 18 Gut 0.35 protein_coding synonymous_variant LOW 69C>T Cys23Cys
M0206498 AILACKOI_00003 4115 9 Gut 0.18 protein_coding upstream_gene_variant MODIFIER -2542G>C None
M0206499 AILACKOI_00008 6041 4 Gut 0.08 protein_coding missense_variant MODERATE 103A>G Ile35Val
M0206500 AILACKOI_00008 6045 4 Gut 0.08 protein_coding synonymous_variant LOW 99G>C Ala33Ala
M0206501 AILACKOI_00003 4907 5 Gut 0.10 protein_coding upstream_gene_variant MODIFIER -3334T>C None
M0206502 AILACKOI_00007 5613 5 Gut 0.10 protein_coding synonymous_variant LOW 582A>G Gly194Gly
M0206503 AILACKOI_00004 2284 6 Gut 0.12 protein_coding missense_variant MODERATE 326C>G Thr109Ser
M0206504 AILACKOI_00005 2637 6 Gut 0.12 protein_coding synonymous_variant LOW 1092C>T Ala364Ala
M0206505 AILACKOI_00003 3915 6 Gut 0.12 protein_coding upstream_gene_variant MODIFIER -2342G>A None
M0206506 AILACKOI_00003 1463 5 Gut 0.10 protein_coding synonymous_variant LOW 111C>G Leu37Leu
M0206507 AILACKOI_00003 1465 5 Gut 0.10 protein_coding missense_variant MODERATE 109C>G Leu37Val
M0206508 AILACKOI_00003 1467 5 Gut 0.10 protein_coding missense_variant MODERATE 107T>C Ile36Thr
M0206509 AILACKOI_00003 1471 5 Gut 0.10 protein_coding missense_variant MODERATE 103G>A Val35Ile
M0206510 AILACKOI_00003 1478 5 Gut 0.10 protein_coding synonymous_variant LOW 96C>G Ala32Ala
M0206511 AILACKOI_00003 1489 5 Gut 0.10 protein_coding missense_variant MODERATE 85C>G His29Asp
M0206512 AILACKOI_00003 1492 5 Gut 0.10 protein_coding missense_variant MODERATE 82G>A Val28Met
M0206513 AILACKOI_00003 1494 5 Gut 0.10 protein_coding missense_variant MODERATE 80C>T Ala27Val
M0206514 AILACKOI_00003 1496 5 Gut 0.10 protein_coding synonymous_variant LOW 78G>C Pro26Pro
M0206515 AILACKOI_00003 1499 5 Gut 0.10 protein_coding synonymous_variant LOW 75A>T Ala25Ala
M0206516 AILACKOI_00003 1510 5 Gut 0.10 protein_coding missense_variant MODERATE 64G>A Val22Ile
M0206517 AILACKOI_00003 1512 5 Gut 0.10 protein_coding missense_variant MODERATE 62C>T Ala21Val
M0206518 AILACKOI_00005 3088 3 Gut 0.06 protein_coding missense_variant MODERATE 641A>G Asp214Gly






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term