Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1333
  Reference Plasmid   NZ_KU355874.1
  Reference Plasmid Size   97819
  Reference Plasmid GC Content   0.50
  Reference Plasmid Mobility Type   conjugative





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0206551 GBKMEKPK_00064 56995 3 Gut 1.00 protein_coding missense_variant MODERATE 530A>C Asp177Ala
M0206552 GBKMEKPK_00064 56996 3 Gut 1.00 protein_coding missense_variant MODERATE 529G>A Asp177Asn
M0206553 GBKMEKPK_00064 57012 3 Gut 1.00 protein_coding synonymous_variant LOW 513C>T Phe171Phe
M0206554 GBKMEKPK_00064 57119 3 Gut 1.00 protein_coding synonymous_variant LOW 406T>C Leu136Leu
M0206555 GBKMEKPK_00065 57920 3 Gut 1.00 protein_coding missense_variant MODERATE 836C>G Thr279Ser
M0206556 GBKMEKPK_00065 57948 3 Gut 1.00 protein_coding synonymous_variant LOW 808C>T Leu270Leu
M0206557 GBKMEKPK_00065 58018 3 Gut 1.00 protein_coding synonymous_variant LOW 738A>G Gly246Gly
M0206558 GBKMEKPK_00065 58033 3 Gut 1.00 protein_coding synonymous_variant LOW 723A>G Val241Val
M0206559 GBKMEKPK_00065 58093 3 Gut 1.00 protein_coding synonymous_variant LOW 663T>G Thr221Thr
M0206560 GBKMEKPK_00065 58132 3 Gut 1.00 protein_coding synonymous_variant LOW 624G>A Ala208Ala
M0206561 GBKMEKPK_00065 58585 3 Gut 1.00 protein_coding synonymous_variant LOW 171A>C Thr57Thr
M0206562 GBKMEKPK_00066 59021 3 Gut 1.00 protein_coding missense_variant MODERATE 316A>G Thr106Ala
M0206563 GBKMEKPK_00066 59116 3 Gut 1.00 protein_coding missense_variant MODERATE 221G>A Gly74Glu
M0206564 GBKMEKPK_00066 59154 3 Gut 1.00 protein_coding synonymous_variant LOW 183C>T Val61Val
M0206565 GBKMEKPK_00067 59693 3 Gut 1.00 protein_coding synonymous_variant LOW 2688G>T Val896Val
M0206566 GBKMEKPK_00067 60119 3 Gut 1.00 protein_coding synonymous_variant LOW 2262T>C Val754Val
M0206567 GBKMEKPK_00067 60191 3 Gut 1.00 protein_coding synonymous_variant LOW 2190G>C Leu730Leu
M0206568 GBKMEKPK_00067 60194 3 Gut 1.00 protein_coding synonymous_variant LOW 2187C>T Ala729Ala
M0206569 GBKMEKPK_00067 60221 3 Gut 1.00 protein_coding synonymous_variant LOW 2160G>A Glu720Glu
M0206570 GBKMEKPK_00067 60377 3 Gut 1.00 protein_coding synonymous_variant LOW 2004T>C Phe668Phe
M0206571 GBKMEKPK_00067 60403 3 Gut 1.00 protein_coding missense_variant MODERATE 1978G>A Ala660Thr
M0206572 GBKMEKPK_00067 60602 3 Gut 1.00 protein_coding synonymous_variant LOW 1779G>T Ser593Ser
M0206573 GBKMEKPK_00067 60677 3 Gut 1.00 protein_coding missense_variant MODERATE 1704C>A Asp568Glu
M0206574 GBKMEKPK_00067 60726 3 Gut 1.00 protein_coding missense_variant MODERATE 1655A>C Gln552Pro
M0206575 GBKMEKPK_00067 60959 3 Gut 1.00 protein_coding synonymous_variant LOW 1422G>T Leu474Leu
M0206576 GBKMEKPK_00067 60971 3 Gut 1.00 protein_coding synonymous_variant LOW 1410C>T Gly470Gly
M0206577 GBKMEKPK_00067 61148 3 Gut 1.00 protein_coding synonymous_variant LOW 1233A>G Ser411Ser
M0206578 GBKMEKPK_00067 61174 3 Gut 1.00 protein_coding missense_variant MODERATE 1207G>A Ala403Thr
M0206579 GBKMEKPK_00067 61505 3 Gut 1.00 protein_coding synonymous_variant LOW 876G>T Thr292Thr
M0206580 GBKMEKPK_00067 61574 3 Gut 1.00 protein_coding synonymous_variant LOW 807A>G Ala269Ala
M0206581 GBKMEKPK_00067 61627 3 Gut 1.00 protein_coding missense_variant MODERATE 754T>C Tyr252His
M0206582 GBKMEKPK_00067 61661 3 Gut 1.00 protein_coding synonymous_variant LOW 720A>G Glu240Glu
M0206583 GBKMEKPK_00067 61676 3 Gut 1.00 protein_coding synonymous_variant LOW 705T>A Leu235Leu
M0206584 GBKMEKPK_00067 61844 3 Gut 1.00 protein_coding synonymous_variant LOW 537T>C Thr179Thr
M0206585 GBKMEKPK_00067 61985 3 Gut 1.00 protein_coding synonymous_variant LOW 396A>G Lys132Lys
M0206586 GBKMEKPK_00067 62015 3 Gut 1.00 protein_coding synonymous_variant LOW 366G>A Glu122Glu
M0206587 GBKMEKPK_00067 62027 3 Gut 1.00 protein_coding missense_variant MODERATE 354A>C Glu118Asp
M0206588 GBKMEKPK_00067 62033 3 Gut 1.00 protein_coding synonymous_variant LOW 348C>T Asp116Asp
M0206589 GBKMEKPK_00067 62042 3 Gut 1.00 protein_coding synonymous_variant LOW 339C>T Phe113Phe
M0206590 GBKMEKPK_00067 62049 3 Gut 1.00 protein_coding missense_variant MODERATE 332G>T Cys111Phe
M0206591 GBKMEKPK_00067 62131 3 Gut 1.00 protein_coding missense_variant MODERATE 250T>C Ser84Pro
M0206592 GBKMEKPK_00068 62524 3 Gut 1.00 protein_coding synonymous_variant LOW 747T>G Gly249Gly
M0206593 GBKMEKPK_00068 62545 3 Gut 1.00 protein_coding synonymous_variant LOW 726T>C Pro242Pro
M0206594 GBKMEKPK_00068 62563 3 Gut 1.00 protein_coding synonymous_variant LOW 708C>A Pro236Pro
M0206595 GBKMEKPK_00068 62566 3 Gut 1.00 protein_coding synonymous_variant LOW 705C>T Tyr235Tyr
M0206596 GBKMEKPK_00068 62608 3 Gut 1.00 protein_coding synonymous_variant LOW 663A>C Arg221Arg
M0206597 GBKMEKPK_00068 62668 3 Gut 1.00 protein_coding synonymous_variant LOW 603A>G Arg201Arg
M0206598 GBKMEKPK_00068 62857 3 Gut 1.00 protein_coding synonymous_variant LOW 414G>A Glu138Glu
M0206599 GBKMEKPK_00068 62880 3 Gut 1.00 protein_coding missense_variant MODERATE 391C>T Pro131Ser
M0206600 GBKMEKPK_00068 62947 3 Gut 1.00 protein_coding missense_variant MODERATE 324T>G His108Gln
M0206601 GBKMEKPK_00068 63000 3 Gut 1.00 protein_coding missense_variant MODERATE 271A>G Lys91Glu
M0206602 GBKMEKPK_00068 63008 3 Gut 1.00 protein_coding missense_variant MODERATE 263C>T Ala88Val
M0206603 GBKMEKPK_00068 63026 3 Gut 1.00 protein_coding missense_variant MODERATE 245G>A Arg82Lys
M0206604 GBKMEKPK_00068 63028 3 Gut 1.00 protein_coding synonymous_variant LOW 243C>A Ile81Ile
M0206605 GBKMEKPK_00068 63029 3 Gut 1.00 protein_coding missense_variant MODERATE 242T>A Ile81Asn
M0206606 GBKMEKPK_00068 63038 3 Gut 1.00 protein_coding missense_variant MODERATE 233T>A Val78Asp
M0206607 GBKMEKPK_00068 63078 3 Gut 1.00 protein_coding missense_variant MODERATE 193A>G Asn65Asp
M0206608 GBKMEKPK_00068 63201 3 Gut 1.00 protein_coding missense_variant MODERATE 70G>C Ala24Pro
M0206609 GBKMEKPK_00068 63208 3 Gut 1.00 protein_coding synonymous_variant LOW 63T>A Thr21Thr
M0206610 GBKMEKPK_00069 63295 3 Gut 1.00 protein_coding missense_variant MODERATE 148T>C Cys50Arg
M0206611 GBKMEKPK_00065 63466 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -4711A>G None
M0206612 GBKMEKPK_00070 63523 3 Gut 1.00 protein_coding missense_variant MODERATE 388T>A Ser130Thr
M0206613 GBKMEKPK_00070 63535 3 Gut 1.00 protein_coding synonymous_variant LOW 376T>C Leu126Leu
M0206614 GBKMEKPK_00070 63580 3 Gut 1.00 protein_coding missense_variant MODERATE 331G>C Val111Leu
M0206615 GBKMEKPK_00070 63601 3 Gut 1.00 protein_coding missense_variant MODERATE 310G>C Val104Leu
M0206616 GBKMEKPK_00070 63650 3 Gut 1.00 protein_coding synonymous_variant LOW 261C>G Gly87Gly
M0206617 GBKMEKPK_00070 63701 3 Gut 1.00 protein_coding missense_variant MODERATE 210C>G Ile70Met
M0206618 GBKMEKPK_00070 63703 3 Gut 1.00 protein_coding missense_variant MODERATE 208A>C Ile70Leu
M0206619 GBKMEKPK_00070 63725 3 Gut 1.00 protein_coding synonymous_variant LOW 186T>C Ala62Ala
M0206620 GBKMEKPK_00070 63733 3 Gut 1.00 protein_coding missense_variant MODERATE 178G>C Glu60Gln
M0206621 GBKMEKPK_00070 63734 3 Gut 1.00 protein_coding synonymous_variant LOW 177T>A Gly59Gly
M0206622 GBKMEKPK_00070 63735 3 Gut 1.00 protein_coding missense_variant MODERATE 176G>A Gly59Asp
M0206623 GBKMEKPK_00070 63737 3 Gut 1.00 protein_coding synonymous_variant LOW 174T>C Val58Val
M0206624 GBKMEKPK_00070 63816 3 Gut 1.00 protein_coding missense_variant MODERATE 95A>T Tyr32Phe
M0206625 GBKMEKPK_00070 63860 3 Gut 1.00 protein_coding synonymous_variant LOW 51T>C His17His
M0206626 GBKMEKPK_00070 63890 3 Gut 1.00 protein_coding synonymous_variant LOW 21G>A Val7Val
M0206627 GBKMEKPK_00071 64093 3 Gut 1.00 protein_coding synonymous_variant LOW 396C>T Leu132Leu
M0206628 GBKMEKPK_00071 64129 3 Gut 1.00 protein_coding synonymous_variant LOW 360C>A Val120Val
M0206629 GBKMEKPK_00071 64138 3 Gut 1.00 protein_coding synonymous_variant LOW 351G>T Val117Val
M0206630 GBKMEKPK_00072 64653 3 Gut 1.00 protein_coding synonymous_variant LOW 540T>A Val180Val
M0206631 GBKMEKPK_00072 64860 3 Gut 1.00 protein_coding synonymous_variant LOW 333C>G Arg111Arg
M0206632 GBKMEKPK_00072 64947 3 Gut 1.00 protein_coding synonymous_variant LOW 246T>C Ser82Ser
M0206633 GBKMEKPK_00072 64965 3 Gut 1.00 protein_coding synonymous_variant LOW 228A>C Thr76Thr
M0206634 GBKMEKPK_00072 65009 3 Gut 1.00 protein_coding missense_variant MODERATE 184C>T Pro62Ser
M0206635 GBKMEKPK_00073 65336 3 Gut 1.00 protein_coding synonymous_variant LOW 1146A>C Ser382Ser
M0206636 GBKMEKPK_00073 65684 3 Gut 1.00 protein_coding synonymous_variant LOW 798T>A Ala266Ala
M0206637 GBKMEKPK_00073 65885 3 Gut 1.00 protein_coding synonymous_variant LOW 597T>C Ala199Ala
M0206638 GBKMEKPK_00073 66004 3 Gut 1.00 protein_coding missense_variant MODERATE 478A>G Thr160Ala
M0206639 GBKMEKPK_00073 66083 3 Gut 1.00 protein_coding synonymous_variant LOW 399A>G Lys133Lys
M0206640 GBKMEKPK_00073 66287 3 Gut 1.00 protein_coding synonymous_variant LOW 195C>T His65His
M0206641 GBKMEKPK_00074 66580 3 Gut 1.00 protein_coding synonymous_variant LOW 888T>C Ser296Ser
M0206642 GBKMEKPK_00074 66727 3 Gut 1.00 protein_coding synonymous_variant LOW 741G>T Leu247Leu
M0206643 GBKMEKPK_00074 66763 3 Gut 1.00 protein_coding synonymous_variant LOW 705G>A Lys235Lys
M0206644 GBKMEKPK_00074 66813 3 Gut 1.00 protein_coding missense_variant MODERATE 655A>C Ile219Leu
M0206645 GBKMEKPK_00074 66925 3 Gut 1.00 protein_coding synonymous_variant LOW 543T>C Asn181Asn
M0206646 GBKMEKPK_00074 66971 3 Gut 1.00 protein_coding missense_variant MODERATE 497A>G Glu166Gly
M0206647 GBKMEKPK_00074 67216 3 Gut 1.00 protein_coding synonymous_variant LOW 252G>A Glu84Glu
M0206648 GBKMEKPK_00074 67243 3 Gut 1.00 protein_coding synonymous_variant LOW 225G>A Arg75Arg
M0206649 GBKMEKPK_00074 67306 3 Gut 1.00 protein_coding synonymous_variant LOW 162G>A Thr54Thr
M0206650 GBKMEKPK_00074 67339 3 Gut 1.00 protein_coding synonymous_variant LOW 129C>T Asn43Asn
M0206651 GBKMEKPK_00074 67366 3 Gut 1.00 protein_coding synonymous_variant LOW 102G>A Thr34Thr
M0206652 GBKMEKPK_00074 67408 3 Gut 1.00 protein_coding synonymous_variant LOW 60C>A Ala20Ala
M0206653 GBKMEKPK_00075 67667 3 Gut 1.00 protein_coding synonymous_variant LOW 504A>G Gln168Gln
M0206654 GBKMEKPK_00075 67776 3 Gut 1.00 protein_coding missense_variant MODERATE 395T>C Val132Ala
M0206655 GBKMEKPK_00075 68159 3 Gut 1.00 protein_coding synonymous_variant LOW 12T>C Asn4Asn
M0206656 GBKMEKPK_00076 68389 3 Gut 1.00 protein_coding synonymous_variant LOW 126G>A Ala42Ala
M0206657 GBKMEKPK_00076 68428 3 Gut 1.00 protein_coding synonymous_variant LOW 87C>T Ser29Ser
M0206658 GBKMEKPK_00077 68661 3 Gut 1.00 protein_coding synonymous_variant LOW 3636A>G Lys1212Lys
M0206659 GBKMEKPK_00077 68934 3 Gut 1.00 protein_coding synonymous_variant LOW 3363A>G Glu1121Glu
M0206660 GBKMEKPK_00077 69649 3 Gut 1.00 protein_coding missense_variant MODERATE 2648C>T Thr883Ile
M0206661 GBKMEKPK_00077 70812 3 Gut 1.00 protein_coding synonymous_variant LOW 1485G>A Pro495Pro
M0206662 GBKMEKPK_00077 70975 3 Gut 1.00 protein_coding missense_variant MODERATE 1322T>A Val441Glu
M0206663 GBKMEKPK_00077 71697 3 Gut 1.00 protein_coding synonymous_variant LOW 600C>A Gly200Gly
M0206664 GBKMEKPK_00077 71901 3 Gut 1.00 protein_coding synonymous_variant LOW 396T>C Asp132Asp
M0206665 GBKMEKPK_00077 71904 3 Gut 1.00 protein_coding synonymous_variant LOW 393G>A Ala131Ala
M0206666 GBKMEKPK_00077 71993 3 Gut 1.00 protein_coding missense_variant MODERATE 304G>A Ala102Thr
M0206667 GBKMEKPK_00077 72132 3 Gut 1.00 protein_coding synonymous_variant LOW 165C>T Asp55Asp
M0206668 GBKMEKPK_00077 72180 3 Gut 1.00 protein_coding missense_variant MODERATE 117C>G Asp39Glu
M0206669 GBKMEKPK_00078 72467 3 Gut 1.00 protein_coding synonymous_variant LOW 471T>C Leu157Leu
M0206670 GBKMEKPK_00078 72806 3 Gut 1.00 protein_coding synonymous_variant LOW 132T>C Ser44Ser
M0206671 GBKMEKPK_00078 72896 3 Gut 1.00 protein_coding synonymous_variant LOW 42A>G Ser14Ser
M0206672 GBKMEKPK_00079 73009 3 Gut 1.00 protein_coding synonymous_variant LOW 234C>T Arg78Arg
M0206673 GBKMEKPK_00079 73048 3 Gut 1.00 protein_coding synonymous_variant LOW 195T>C Arg65Arg
M0206674 GBKMEKPK_00079 73093 3 Gut 1.00 protein_coding synonymous_variant LOW 150C>T Val50Val
M0206675 GBKMEKPK_00079 73137 3 Gut 1.00 protein_coding missense_variant MODERATE 106G>A Glu36Lys
M0206676 GBKMEKPK_00079 73147 3 Gut 1.00 protein_coding synonymous_variant LOW 96T>C Pro32Pro
M0206677 GBKMEKPK_00079 73207 3 Gut 1.00 protein_coding synonymous_variant LOW 36T>G Pro12Pro
M0206678 GBKMEKPK_00080 73323 3 Gut 1.00 protein_coding synonymous_variant LOW 1065T>C Asp355Asp
M0206679 GBKMEKPK_00080 73335 3 Gut 1.00 protein_coding synonymous_variant LOW 1053T>C Arg351Arg
M0206680 GBKMEKPK_00080 73338 3 Gut 1.00 protein_coding synonymous_variant LOW 1050A>G Lys350Lys
M0206681 GBKMEKPK_00080 73341 3 Gut 1.00 protein_coding synonymous_variant LOW 1047A>G Glu349Glu
M0206682 GBKMEKPK_00080 73386 3 Gut 1.00 protein_coding synonymous_variant LOW 1002A>G Pro334Pro
M0206683 GBKMEKPK_00080 73452 3 Gut 1.00 protein_coding synonymous_variant LOW 936C>T Gly312Gly
M0206684 GBKMEKPK_00080 73614 3 Gut 1.00 protein_coding synonymous_variant LOW 774A>G Gly258Gly
M0206685 GBKMEKPK_00080 74199 3 Gut 1.00 protein_coding synonymous_variant LOW 189C>T Leu63Leu
M0206686 GBKMEKPK_00080 74271 3 Gut 1.00 protein_coding synonymous_variant LOW 117C>T Gly39Gly
M0206687 GBKMEKPK_00080 74340 3 Gut 1.00 protein_coding synonymous_variant LOW 48T>G Thr16Thr
M0206688 GBKMEKPK_00081 74432 3 Gut 1.00 protein_coding synonymous_variant LOW 771A>G Gln257Gln
M0206689 GBKMEKPK_00081 74904 3 Gut 1.00 protein_coding missense_variant MODERATE 299T>C Leu100Pro
M0206690 GBKMEKPK_00081 74963 3 Gut 1.00 protein_coding synonymous_variant LOW 240G>A Ala80Ala
M0206691 GBKMEKPK_00081 75029 3 Gut 1.00 protein_coding synonymous_variant LOW 174A>C Thr58Thr
M0206692 GBKMEKPK_00081 75181 3 Gut 1.00 protein_coding missense_variant MODERATE 22C>A Leu8Ile
M0206693 GBKMEKPK_00082 75502 3 Gut 1.00 protein_coding synonymous_variant LOW 156A>G Val52Val
M0206694 GBKMEKPK_00084 76950 3 Gut 1.00 protein_coding missense_variant MODERATE 946A>G Ile316Val
M0206695 GBKMEKPK_00084 77005 3 Gut 1.00 protein_coding synonymous_variant LOW 891G>A Pro297Pro
M0206696 GBKMEKPK_00084 77158 3 Gut 1.00 protein_coding synonymous_variant LOW 738C>T Tyr246Tyr
M0206697 GBKMEKPK_00084 77785 3 Gut 1.00 protein_coding synonymous_variant LOW 111T>C Gly37Gly
M0206698 GBKMEKPK_00085 78147 3 Gut 1.00 protein_coding missense_variant MODERATE 661C>A Leu221Ile
M0206699 GBKMEKPK_00085 78184 3 Gut 1.00 protein_coding synonymous_variant LOW 624C>T Gly208Gly
M0206700 GBKMEKPK_00085 78221 3 Gut 1.00 protein_coding missense_variant MODERATE 587G>A Cys196Tyr
M0206701 GBKMEKPK_00085 78293 3 Gut 1.00 protein_coding missense_variant MODERATE 515G>A Ser172Asn
M0206702 GBKMEKPK_00085 78559 3 Gut 1.00 protein_coding synonymous_variant LOW 249A>G Gly83Gly
M0206703 GBKMEKPK_00085 78564 3 Gut 1.00 protein_coding missense_variant MODERATE 244A>G Thr82Ala
M0206704 GBKMEKPK_00086 79190 3 Gut 1.00 protein_coding missense_variant MODERATE 922G>A Asp308Asn
M0206705 GBKMEKPK_00086 79266 3 Gut 1.00 protein_coding synonymous_variant LOW 846G>A Lys282Lys
M0206706 GBKMEKPK_00086 79761 3 Gut 1.00 protein_coding synonymous_variant LOW 351G>C Ser117Ser
M0206707 GBKMEKPK_00083 81092 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -4456T>C None
M0206708 GBKMEKPK_00083 81103 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -4467A>G None
M0206709 GBKMEKPK_00084 81742 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -3847G>A None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism
GBKMEKPK_00009 ARO:3001878 100 1.15e-202 1 291 1.0000 1.0000 cephalosporin CTX-M beta-lactamase antibiotic inactivation
GBKMEKPK_00011 ARO:3004623 100 4.76e-213 1 286 1.0000 1.0000 aminoglycoside antibiotic AAC(3) antibiotic inactivation
GBKMEKPK_00016 ARO:3000873 100 5.12e-208 1 286 1.0000 1.0000 monobactam TEM beta-lactamase antibiotic inactivation






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant
GBKMEKPK_00025 PHI:3113 stbA 98.2 3.7e-182 1 326 1.0000 1.0000 rodents neonatal meningitis stability protein for the plasmid reduced virulence






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
GBKMEKPK_00090 AHF22950.1|GH23 100 5.89e-138 1 186 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
GBKMEKPK_00053 3.A.7.10.1 99.9 0 1 763 1.0000 7.9479 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.7 The Type IV (Conjugal DNA-Protein Transfer or VirB) Secretory Pathway (IVSP) Family
GBKMEKPK_00054 3.A.7.10.1 98.9 2.3e-206 1 356 1.0000 3.7083 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.7 The Type IV (Conjugal DNA-Protein Transfer or VirB) Secretory Pathway (IVSP) Family
GBKMEKPK_00055 3.A.7.10.1 99.5 2.7e-243 1 402 1.0000 4.1875 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.7 The Type IV (Conjugal DNA-Protein Transfer or VirB) Secretory Pathway (IVSP) Family
GBKMEKPK_00057 1.E.53.1.10 88.4 5.4e-16 9 51 0.8431 1.0000 1 Channels/Pores 1.E Holins 1.E.53 The Toxic Hok/Gef Protein (Hok/Gef) Family
GBKMEKPK_00063 9.B.40.1.2 86.1 0 1 722 1.0000 0.9691 9 Incompletely Characterized Transport Systems 9.B Putative transport proteins 9.B.40 The DotA/TraY (DotA/TraY) Family
GBKMEKPK_00074 3.A.7.10.1 99.7 1.4e-184 1 327 1.0000 3.4063 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.7 The Type IV (Conjugal DNA-Protein Transfer or VirB) Secretory Pathway (IVSP) Family
GBKMEKPK_00075 3.A.7.10.1 99.1 7.4e-129 1 230 1.0000 2.3958 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.7 The Type IV (Conjugal DNA-Protein Transfer or VirB) Secretory Pathway (IVSP) Family
GBKMEKPK_00076 3.A.7.10.1 100 1.3e-57 1 115 1.0000 1.1979 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.7 The Type IV (Conjugal DNA-Protein Transfer or VirB) Secretory Pathway (IVSP) Family
GBKMEKPK_00079 3.A.7.10.1 97.9 1.3e-55 1 96 1.0000 1.0000 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.7 The Type IV (Conjugal DNA-Protein Transfer or VirB) Secretory Pathway (IVSP) Family
GBKMEKPK_00080 3.A.7.10.1 100 3.3e-222 1 382 1.0000 3.9792 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.7 The Type IV (Conjugal DNA-Protein Transfer or VirB) Secretory Pathway (IVSP) Family
GBKMEKPK_00081 3.A.7.10.1 99.6 6.2e-159 1 272 1.0000 2.8333 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.7 The Type IV (Conjugal DNA-Protein Transfer or VirB) Secretory Pathway (IVSP) Family
GBKMEKPK_00082 3.A.7.10.1 100 6e-87 1 152 1.0000 1.5833 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.7 The Type IV (Conjugal DNA-Protein Transfer or VirB) Secretory Pathway (IVSP) Family