Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1381
  Reference Plasmid   NZ_MN480762.1
  Reference Plasmid Size   190254
  Reference Plasmid GC Content   0.33
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0208581 ILENEDLC_00061 55717 3 Gut 0.15 protein_coding missense_variant MODERATE 1126T>C Tyr376His
M0208582 ILENEDLC_00061 55761 3 Gut 0.15 protein_coding synonymous_variant LOW 1170T>C Asn390Asn
M0208583 ILENEDLC_00061 55905 3 Gut 0.15 protein_coding synonymous_variant LOW 1314T>C Ala438Ala
M0208584 ILENEDLC_00061 55906 3 Gut 0.15 protein_coding missense_variant MODERATE 1315G>A Val439Ile
M0208585 ILENEDLC_00061 56049 3 Gut 0.15 protein_coding synonymous_variant LOW 1458G>A Glu486Glu
M0208586 ILENEDLC_00061 56150 3 Gut 0.15 protein_coding missense_variant MODERATE 1559C>T Pro520Leu
M0208587 ILENEDLC_00061 56253 3 Gut 0.15 protein_coding synonymous_variant LOW 1662G>T Pro554Pro
M0208588 ILENEDLC_00061 56310 3 Gut 0.15 protein_coding synonymous_variant LOW 1719T>C Val573Val
M0208589 ILENEDLC_00061 56364 3 Gut 0.15 protein_coding synonymous_variant LOW 1773T>C Leu591Leu
M0208590 ILENEDLC_00061 56409 3 Gut 0.15 protein_coding synonymous_variant LOW 1818G>A Ser606Ser
M0208591 ILENEDLC_00061 56816 3 Gut 0.15 protein_coding missense_variant MODERATE 2225A>C Lys742Thr
M0208592 ILENEDLC_00061 57042 3 Gut 0.15 protein_coding synonymous_variant LOW 2451C>T Arg817Arg
M0208593 ILENEDLC_00061 57072 3 Gut 0.15 protein_coding synonymous_variant LOW 2481C>T Phe827Phe
M0208594 ILENEDLC_00061 57123 3 Gut 0.15 protein_coding synonymous_variant LOW 2532T>C Thr844Thr
M0208595 ILENEDLC_00061 57189 3 Gut 0.15 protein_coding synonymous_variant LOW 2598C>G Gly866Gly
M0208596 ILENEDLC_00061 57201 3 Gut 0.15 protein_coding synonymous_variant LOW 2610A>T Gly870Gly
M0208597 ILENEDLC_00061 57486 3 Gut 0.15 protein_coding synonymous_variant LOW 2895C>T Ile965Ile
M0208598 ILENEDLC_00061 57690 3 Gut 0.15 protein_coding synonymous_variant LOW 3099A>G Thr1033Thr
M0208599 ILENEDLC_00061 57702 3 Gut 0.15 protein_coding synonymous_variant LOW 3111T>C Asn1037Asn
M0208600 ILENEDLC_00061 57993 3 Gut 0.15 protein_coding synonymous_variant LOW 3402C>T His1134His
M0208601 ILENEDLC_00061 58224 3 Gut 0.15 protein_coding synonymous_variant LOW 3633G>T Thr1211Thr
M0208602 ILENEDLC_00061 58227 3 Gut 0.15 protein_coding missense_variant MODERATE 3636T>G Asp1212Glu
M0208603 ILENEDLC_00061 58362 3 Gut 0.15 protein_coding synonymous_variant LOW 3771C>T Leu1257Leu
M0208604 ILENEDLC_00061 58603 3 Gut 0.15 protein_coding missense_variant MODERATE 4012A>C Ile1338Leu
M0208605 ILENEDLC_00061 58812 3 Gut 0.15 protein_coding synonymous_variant LOW 4221T>C Ile1407Ile
M0208606 ILENEDLC_00061 59053 3 Gut 0.15 protein_coding missense_variant MODERATE 4462T>G Ser1488Ala
M0208607 ILENEDLC_00061 59211 3 Gut 0.15 protein_coding missense_variant MODERATE 4620G>T Gln1540His
M0208608 ILENEDLC_00061 59292 3 Gut 0.15 protein_coding synonymous_variant LOW 4701A>T Ala1567Ala
M0208609 ILENEDLC_00061 59298 3 Gut 0.15 protein_coding synonymous_variant LOW 4707A>G Gln1569Gln
M0208610 ILENEDLC_00061 59373 3 Gut 0.15 protein_coding synonymous_variant LOW 4782C>G Ala1594Ala
M0208611 ILENEDLC_00061 59406 3 Gut 0.15 protein_coding synonymous_variant LOW 4815T>C Arg1605Arg
M0208612 ILENEDLC_00061 59452 3 Gut 0.15 protein_coding synonymous_variant LOW 4861T>C Leu1621Leu
M0208613 ILENEDLC_00061 59457 3 Gut 0.15 protein_coding synonymous_variant LOW 4866T>C Asp1622Asp
M0208614 ILENEDLC_00061 59658 3 Gut 0.15 protein_coding synonymous_variant LOW 5067T>C Val1689Val
M0208615 ILENEDLC_00061 59664 3 Gut 0.15 protein_coding synonymous_variant LOW 5073T>C Asp1691Asp
M0208616 ILENEDLC_00061 59673 3 Gut 0.15 protein_coding synonymous_variant LOW 5082A>G Lys1694Lys
M0208617 ILENEDLC_00061 59695 3 Gut 0.15 protein_coding missense_variant MODERATE 5104A>G Lys1702Glu
M0208618 ILENEDLC_00061 59795 3 Gut 0.15 protein_coding missense_variant MODERATE 5204C>G Thr1735Ser






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
ILENEDLC_00062 1.C.21.1.4 95.7 1.5e-21 5 51 0.9216 0.9792 1 Channels/Pores 1.C Pore-Forming Toxins (Proteins and Peptides) 1.C.21 The Lacticin 481 (Lacticin 481) Family
ILENEDLC_00065 3.A.1.134.1 98.8 2e-132 1 245 1.0000 1.0000 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
ILENEDLC_00066 3.A.1.134.1 99.8 0 1 635 1.0000 2.5918 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
ILENEDLC_00073 1.C.21.1.7 100 8.3e-26 1 56 1.0000 1.0000 1 Channels/Pores 1.C Pore-Forming Toxins (Proteins and Peptides) 1.C.21 The Lacticin 481 (Lacticin 481) Family
ILENEDLC_00075 3.A.1.111.6 95.2 0 1 692 1.0000 1.0000 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily