Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1387
  Reference Plasmid   NZ_MT162143.1
  Reference Plasmid Size   138284
  Reference Plasmid GC Content   0.51
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0208807 IALKMIHO_00040 47706 4 Gut 0.13 protein_coding upstream_gene_variant MODIFIER -4664A>G None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group
IALKMIHO_00037 Arsenic (As), Antimony (Sb) 99.3 3.5e-77 1 141 1.0000 1.0000 experiment
IALKMIHO_00038 Arsenic (As), Antimony (Sb) 99.3 1.7e-231 1 429 1.0000 1.0000 experiment
IALKMIHO_00039 Arsenic (As), Antimony (Sb) 99 0 1 583 1.0000 1.0000 experiment
IALKMIHO_00040 Arsenic (As), Antimony (Sb) 98.3 1.9e-67 20 139 0.8633 1.0000 experiment
IALKMIHO_00041 Arsenic (As), Antimony (Sb), Bismuth (Bi) 100 8.1e-64 1 117 1.0000 1.0000 experiment
IALKMIHO_00037 Arsenic (As) 100 1.6e-75 1 141 1.0000 1.0000 prediction
IALKMIHO_00038 Arsenic (As), Antimony (Sb) 100 6.9e-231 1 429 1.0000 1.0000 prediction
IALKMIHO_00039 Arsenic (As), Antimony (Sb) 100 0 1 583 1.0000 1.0000 prediction
IALKMIHO_00040 Arsenic (As) 100 5.1e-66 20 139 0.8633 1.0000 prediction
IALKMIHO_00041 Arsenic (As) 100 1.9e-61 1 117 1.0000 1.0000 prediction






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant
IALKMIHO_00030 PHI:124154 bcsA (=DS0823_v1_2374) 71.6 3e-298 1 680 0.9673 0.9756 eudicots soft rot; blackleg disease cellulose synthase unaffected pathogenicity
IALKMIHO_00093 PHI:3317 hsdR 73 0 1 1038 1.0000 1.0000 rodents Glasser's disease involved in pathogenicity reduced virulence






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
IALKMIHO_00030 QJJ94211.1|GT2 100 0 1 703 1 1
IALKMIHO_00034 AKR81508.1|GH8 100 2.58e-253 1 333 1 1
IALKMIHO_00071 AUV34601.1|GH32 100 0 1 466 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
IALKMIHO_00038 3.A.4.1.1 93.7 1.3e-219 1 429 1.0000 1.0000 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.4 The Arsenite-Antimonite (ArsAB) Efflux Family
IALKMIHO_00039 3.A.4.1.1 85.5 1.5e-282 1 581 0.9966 1.3543 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.4 The Arsenite-Antimonite (ArsAB) Efflux Family
IALKMIHO_00072 4.A.1.2.1 97.4 5.9e-247 1 456 1.0000 1.0000 4 Group Translocators 4.A Phosphotransfer-driven Group Translocators (PTS) 4.A.1 The PTS Glucose-Glucoside (Glc) Family
IALKMIHO_00073 1.B.3.1.2 89.7 9.8e-267 1 505 1.0000 1.0000 1 Channels/Pores 1.B β-Barrel Porins 1.B.3 The Sugar Porin (SP) Family
IALKMIHO_00129 1.E.53.1.7 81.7 3e-28 1 71 1.0000 1.0000 1 Channels/Pores 1.E Holins 1.E.53 The Toxic Hok/Gef Protein (Hok/Gef) Family
IALKMIHO_00148 2.A.7.3.26 84.2 7e-126 1 273 1.0000 0.9070 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.7 The Drug/Metabolite Transporter (DMT) Superfamily
IALKMIHO_00151 4.A.7.1.2 100 1.5e-228 1 418 1.0000 4.4000 4 Group Translocators 4.A Phosphotransfer-driven Group Translocators (PTS) 4.A.7 The PTS L-Ascorbate (L-Asc) Family
IALKMIHO_00152 4.A.7.1.2 100 6.1e-45 1 95 1.0000 1.0000 4 Group Translocators 4.A Phosphotransfer-driven Group Translocators (PTS) 4.A.7 The PTS L-Ascorbate (L-Asc) Family