Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1388
  Reference Plasmid   NZ_MW002458.1
  Reference Plasmid Size   10166
  Reference Plasmid GC Content   0.42
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0208808 HBAANAPK_00012 7347 4 Gut 0.27 protein_coding synonymous_variant LOW 948T>G Val316Val
M0208809 HBAANAPK_00006 3496 4 Gut 0.27 protein_coding synonymous_variant LOW 228C>T Asp76Asp
M0208810 HBAANAPK_00002 4018 3 Gut 0.20 protein_coding upstream_gene_variant MODIFIER -2020A>G None
M0208811 HBAANAPK_00007 4768 3 Gut 0.20 protein_coding synonymous_variant LOW 594C>T Ala198Ala
M0208812 HBAANAPK_00010 5813 5 Gut 0.33 protein_coding synonymous_variant LOW 315A>G Gln105Gln
M0208813 HBAANAPK_00008 5295 3 Gut 0.20 protein_coding synonymous_variant LOW 144A>G Thr48Thr
M0208814 HBAANAPK_00008 5371 5 Gut 0.33 protein_coding missense_variant MODERATE 220A>G Lys74Glu
M0208815 HBAANAPK_00009 5410 3 Gut 0.20 protein_coding missense_variant MODERATE 56C>T Pro19Leu
M0208816 HBAANAPK_00009 5459 3 Gut 0.20 protein_coding missense_variant MODERATE 7G>T Asp3Tyr
M0208817 HBAANAPK_00010 5512 5 Gut 0.33 protein_coding missense_variant MODERATE 14C>T Ala5Val
M0208818 HBAANAPK_00010 5660 3 Gut 0.20 protein_coding synonymous_variant LOW 162T>A Gly54Gly
M0208819 HBAANAPK_00002 1234 3 Gut 0.20 protein_coding synonymous_variant LOW 765G>T Arg255Arg
M0208820 HBAANAPK_00002 1253 4 Gut 0.27 protein_coding missense_variant MODERATE 746A>C Gln249Pro
M0208821 HBAANAPK_00002 1339 3 Gut 0.20 protein_coding synonymous_variant LOW 660C>A Ile220Ile
M0208822 HBAANAPK_00002 1351 4 Gut 0.27 protein_coding synonymous_variant LOW 648T>C Thr216Thr
M0208823 HBAANAPK_00002 1352 4 Gut 0.27 protein_coding missense_variant MODERATE 647C>G Thr216Ser
M0208824 HBAANAPK_00002 1396 4 Gut 0.27 protein_coding synonymous_variant LOW 603A>C Ala201Ala
M0208825 HBAANAPK_00002 1456 3 Gut 0.20 protein_coding synonymous_variant LOW 543A>G Arg181Arg
M0208826 HBAANAPK_00002 1471 3 Gut 0.20 protein_coding synonymous_variant LOW 528A>G Lys176Lys
M0208827 HBAANAPK_00002 1555 3 Gut 0.20 protein_coding synonymous_variant LOW 444C>T Ile148Ile
M0208828 HBAANAPK_00002 1589 4 Gut 0.27 protein_coding missense_variant MODERATE 410A>G Glu137Gly
M0208829 HBAANAPK_00002 1609 3 Gut 0.20 protein_coding synonymous_variant LOW 390G>A Lys130Lys
M0208830 HBAANAPK_00002 1694 3 Gut 0.20 protein_coding missense_variant MODERATE 305G>A Arg102Lys
M0208831 HBAANAPK_00002 1886 3 Gut 0.20 protein_coding missense_variant MODERATE 113G>A Arg38Gln
M0208832 HBAANAPK_00002 1924 3 Gut 0.20 protein_coding synonymous_variant LOW 75T>C Tyr25Tyr
M0208833 HBAANAPK_00002 1963 3 Gut 0.20 protein_coding synonymous_variant LOW 36T>C Thr12Thr
M0208834 HBAANAPK_00002 1987 3 Gut 0.20 protein_coding synonymous_variant LOW 12G>A Lys4Lys
M0208835 HBAANAPK_00003 2001 4 Gut 0.27 protein_coding synonymous_variant LOW 597G>A Gly199Gly
M0208836 HBAANAPK_00003 2031 4 Gut 0.27 protein_coding synonymous_variant LOW 567A>G Lys189Lys
M0208837 HBAANAPK_00009 5450 3 Gut 0.20 protein_coding missense_variant MODERATE 16G>A Val6Ile
M0208838 HBAANAPK_00010 5768 3 Gut 0.20 protein_coding synonymous_variant LOW 270G>T Ala90Ala






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term