Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1396
  Reference Plasmid   NZ_OK031035.1
  Reference Plasmid Size   26160
  Reference Plasmid GC Content   0.26
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0116731 FIIIMJNI_00019 16875 3 Skin 0.07 protein_coding upstream_gene_variant MODIFIER -225T>C None
M0116732 FIIIMJNI_00019 16876 3 Skin 0.07 protein_coding upstream_gene_variant MODIFIER -224A>T None
M0116733 FIIIMJNI_00019 16878 3 Skin 0.07 protein_coding upstream_gene_variant MODIFIER -222T>A None
M0116734 FIIIMJNI_00019 16882 3 Skin 0.07 protein_coding upstream_gene_variant MODIFIER -218A>T None
M0116735 FIIIMJNI_00019 16893 3 Skin 0.07 protein_coding upstream_gene_variant MODIFIER -207G>A None
M0116736 FIIIMJNI_00019 16896 3 Skin 0.07 protein_coding upstream_gene_variant MODIFIER -204T>A None
M0116737 FIIIMJNI_00019 16948 4 Skin 0.09 protein_coding upstream_gene_variant MODIFIER -152T>C None
M0116738 FIIIMJNI_00019 16957 5 Skin 0.11 protein_coding upstream_gene_variant MODIFIER -143A>T None
M0116739 FIIIMJNI_00019 16959 4 Skin 0.09 protein_coding upstream_gene_variant MODIFIER -141G>A None
M0116740 FIIIMJNI_00019 17034 4 Skin 0.09 protein_coding upstream_gene_variant MODIFIER -66A>T None
M0116741 FIIIMJNI_00023 20280 3 Skin 0.07 protein_coding synonymous_variant LOW 420A>G Leu140Leu
M0116742 FIIIMJNI_00023 20594 3 Skin 0.07 protein_coding missense_variant MODERATE 106G>A Val36Met
M0116743 FIIIMJNI_00024 20889 3 Skin 0.07 protein_coding missense_variant MODERATE 151T>G Ser51Ala
M0116744 FIIIMJNI_00024 20946 6 Skin 0.14 protein_coding missense_variant MODERATE 94A>G Ile32Val
M0116745 FIIIMJNI_00025 21317 4 Skin 0.09 protein_coding synonymous_variant LOW 6C>T Asn2Asn
M0116746 FIIIMJNI_00025 22262 3 Skin 0.07 protein_coding synonymous_variant LOW 951C>T Tyr317Tyr
M0116747 FIIIMJNI_00025 22424 3 Skin 0.07 protein_coding synonymous_variant LOW 1113G>A Ala371Ala
M0116748 FIIIMJNI_00018 15741 4 Skin 0.09 protein_coding missense_variant MODERATE 317T>C Val106Ala
M0116749 FIIIMJNI_00018 15775 3 Skin 0.07 protein_coding synonymous_variant LOW 351A>G Leu117Leu
M0116750 FIIIMJNI_00018 15850 4 Skin 0.09 protein_coding synonymous_variant LOW 426G>A Ser142Ser
M0116751 FIIIMJNI_00018 15922 4 Skin 0.09 protein_coding synonymous_variant LOW 498T>C Thr166Thr
M0116752 FIIIMJNI_00018 15937 3 Skin 0.07 protein_coding synonymous_variant LOW 513C>T Asp171Asp
M0116753 FIIIMJNI_00019 16429 4 Skin 0.09 protein_coding upstream_gene_variant MODIFIER -671C>T None
M0116754 FIIIMJNI_00019 16676 3 Skin 0.07 protein_coding upstream_gene_variant MODIFIER -424C>T None
M0116755 FIIIMJNI_00018 16390 3 Skin 0.07 protein_coding synonymous_variant LOW 966C>T Phe322Phe
M0116756 FIIIMJNI_00018 15469 4 Skin 0.09 protein_coding synonymous_variant LOW 45T>C Asn15Asn
M0116757 FIIIMJNI_00018 15488 4 Skin 0.09 protein_coding missense_variant MODERATE 64T>A Ser22Thr
M0116758 FIIIMJNI_00018 15501 4 Skin 0.09 protein_coding missense_variant MODERATE 77C>A Thr26Lys
M0116759 FIIIMJNI_00018 15502 4 Skin 0.09 protein_coding synonymous_variant LOW 78G>A Thr26Thr
M0116760 FIIIMJNI_00018 15523 4 Skin 0.09 protein_coding synonymous_variant LOW 99G>A Lys33Lys
M0116761 FIIIMJNI_00022 19461 3 Skin 0.07 protein_coding missense_variant MODERATE 82A>C Met28Leu
M0116762 FIIIMJNI_00025 22863 3 Skin 0.07 protein_coding synonymous_variant LOW 1552A>C Arg518Arg
M0116763 FIIIMJNI_00025 22676 3 Skin 0.07 protein_coding synonymous_variant LOW 1365G>A Leu455Leu
M0116764 FIIIMJNI_00025 22678 3 Skin 0.07 protein_coding missense_variant MODERATE 1367A>G Asn456Ser
M0116765 FIIIMJNI_00025 22679 3 Skin 0.07 protein_coding synonymous_variant LOW 1368C>T Asn456Asn
M0116766 FIIIMJNI_00025 22683 3 Skin 0.07 protein_coding synonymous_variant LOW 1372T>C Leu458Leu
M0116767 FIIIMJNI_00020 18652 3 Skin 0.07 protein_coding synonymous_variant LOW 696T>C Asp232Asp
M0116768 FIIIMJNI_00022 18682 3 Skin 0.07 protein_coding upstream_gene_variant MODIFIER -698A>C None
M0116769 FIIIMJNI_00022 18684 3 Skin 0.07 protein_coding upstream_gene_variant MODIFIER -696A>C None
M0116770 FIIIMJNI_00021 18766 3 Skin 0.07 protein_coding synonymous_variant LOW 558C>T Val186Val
M0116771 FIIIMJNI_00021 18818 3 Skin 0.07 protein_coding missense_variant MODERATE 506G>A Ser169Asn
M0116772 FIIIMJNI_00021 18957 3 Skin 0.07 protein_coding missense_variant MODERATE 367G>A Asp123Asn
M0116773 FIIIMJNI_00021 18970 3 Skin 0.07 protein_coding missense_variant MODERATE 354T>A Asn118Lys
M0116774 FIIIMJNI_00021 19314 4 Skin 0.09 protein_coding missense_variant MODERATE 10G>A Asp4Asn






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
FIIIMJNI_00006 1.C.21.1.5 83.9 3e-23 1 56 0.9825 0.9825 1 Channels/Pores 1.C Pore-Forming Toxins (Proteins and Peptides) 1.C.21 The Lacticin 481 (Lacticin 481) Family
FIIIMJNI_00011 3.A.1.111.7 76.7 5.2e-295 2 691 0.9986 0.9942 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
FIIIMJNI_00012 3.A.1.124.3 85.8 1.6e-139 1 289 0.9570 0.9931 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
FIIIMJNI_00013 3.A.1.124.3 71.6 3.6e-89 1 250 1.0000 0.8591 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
FIIIMJNI_00014 3.A.1.124.3 77 6.3e-102 1 244 0.9959 0.8385 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
FIIIMJNI_00015 9.B.351.1.3 100 1.1e-38 1 92 1.0000 1.0000 9 Incompletely Characterized Transport Systems 9.B Putative transport proteins 9.B.351 The Lantibiotic Immunity Protein (LIP) Family