Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1400
  Reference Plasmid   NZ_OL790812.1
  Reference Plasmid Size   4088254
  Reference Plasmid GC Content   0.39
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0208908 FMIGHEMP_03207 3435747 3 Gut 0.75 protein_coding missense_variant MODERATE 334G>A Val112Ile






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition
FMIGHEMP_00038 VFG000332 LOS 77.7 5.1e-142 1 310 0.9936 1.0065 Immune modulation ADP-L-glycero-D-mannoheptose-6-epimerase experiment
FMIGHEMP_00052 VFG048797 Capsule 79.1 1.7e-179 1 388 1.0 1 Immune modulation UDP-glucose 6-dehydrogenase experiment
FMIGHEMP_00128 VFG046465 EF-Tu 80.9 4e-192 1 393 0.9975 0.9975 Adherence elongation factor Tu experiment
FMIGHEMP_00696 VFG049144 AcrAB 75.9 0 1 1044 0.9924 0.9962 Antimicrobial activity/Competitive advantage acriflavine resistance protein B experiment
FMIGHEMP_00893 VFG013418 LOS 78.1 6e-85 1 192 1.0 0.9897 Immune modulation phosphoheptose isomerase experiment
FMIGHEMP_00920 VFG010906 CsrA 83.6 5.8e-21 1 55 0.8871 0.8594 Regulation carbon storage regulator CsrA experiment
FMIGHEMP_00928 VFG018241 AI-2 74.9 2.1e-73 1 171 1.0 0.9942 Biofilm S-ribosylhomocysteinase experiment
FMIGHEMP_01101 VFG000478 Fur 86.4 3.3e-75 1 147 0.9932 0.98 Regulation ferric iron uptake transcriptional regulator experiment
FMIGHEMP_01217 VFG048830 Capsule 85.9 2.5e-233 1 468 1.0 1 Immune modulation NADP-dependent phosphogluconate dehydrogenase experiment
FMIGHEMP_01282 VFG038845 Polar flagella 70.9 2e-96 2 244 0.9605 0.9605 Motility NeuA protein experiment
FMIGHEMP_01308 VFG038380 T6SS 76.4 2.4e-231 1 492 1.0 1 Effector delivery system Type VI secretion system contractile sheath large subunit TssC/VipB experiment
FMIGHEMP_01310 VFG038365 T6SS 89.5 2.4e-93 1 172 1.0 1 Effector delivery system HcpA-like protein experiment
FMIGHEMP_01430 VFG038840 Polar flagella 77.5 3.1e-102 1 244 1.0 1 Motility short chain dehydrogenase/reductase family oxidoreductase experiment
FMIGHEMP_01671 VFG013465 LOS 80.2 6.1e-134 1 283 0.9965 0.9965 Immune modulation 2-dehydro-3-deoxyphosphooctonate aldolase experiment
FMIGHEMP_01700 VFG038365 T6SS 89.5 2.4e-93 1 172 1.0 1 Effector delivery system HcpA-like protein experiment
FMIGHEMP_02059 VFG013346 LOS 70.3 4.2e-117 10 299 0.9635 0.9831 Immune modulation glucosephosphate uridylyltransferase experiment
FMIGHEMP_02237 VFG002319 Flagella 83.5 8.3e-108 1 237 0.9875 0.9875 Motility flagellar biosynthesis sigma factor experiment
FMIGHEMP_02250 VFG002329 Flagella 81.7 2.7e-149 5 332 0.988 0.9939 Motility flagellar motor switch protein G experiment
FMIGHEMP_02252 VFG002331 Flagella 79.8 1.5e-203 1 451 0.9869 0.9934 Motility flagellum-specific ATP synthase FliI experiment
FMIGHEMP_02256 VFG002335 Flagella 79 1.5e-155 1 343 1.0 1.0269 Motility flagellar motor switch protein FliM experiment
FMIGHEMP_02257 VFG002336 Flagella 70.5 1.1e-43 1 136 1.0 0.9855 Motility flagellar motor switch protein FliN experiment
FMIGHEMP_02259 VFG002338 Flagella 78.3 6.8e-100 18 256 0.9336 0.956 Motility flagellar biosynthetic protein FliP experiment
FMIGHEMP_02260 VFG002339 Flagella 77.5 2.1e-32 1 89 1.0 1 Motility flagellar biosynthetic protein FliQ experiment
FMIGHEMP_02266 VFG002344 Flagella 74 9.9e-145 11 368 0.9728 0.9598 Motility flagellar P-ring protein precursor FlgI experiment
FMIGHEMP_02267 VFG002345 Flagella 78.1 1.3e-95 29 247 0.8866 0.9202 Motility flagellar L-ring protein precursor FlgH experiment
FMIGHEMP_02268 VFG002346 Flagella 84.2 8.3e-122 1 260 1.0 1 Motility flagellar basal-body rod protein FlgG experiment
FMIGHEMP_02272 VFG002350 Flagella 77.6 1.7e-54 1 134 1.0 1 Motility flagellar basal-body rod protein FlgC experiment
FMIGHEMP_02278 VFG002356 Flagella 77.9 2.2e-302 1 692 0.9943 1 Motility flagellar biosynthesis protein FlhA experiment
FMIGHEMP_02280 VFG043205 Flagella 74.1 3e-80 7 218 0.9725 0.9907 Motility chemotaxis regulator CheZ experiment
FMIGHEMP_02281 VFG043206 Flagella 83.7 3.6e-57 1 129 1.0 1 Motility chemotaxis regulatory protein CheY experiment
FMIGHEMP_02282 VFG043207 Flagella 76 1.1e-148 1 350 1.0 1.0029 Motility chemotaxis-specific methylesterase CheB experiment
FMIGHEMP_02286 VFG043210 Flagella 81 2.7e-65 8 160 0.9217 0.9273 Motility purine-binding chemotaxis protein CheW experiment
FMIGHEMP_02289 VFG043213 Flagella 70.6 3.5e-113 1 289 1.0 0.9797 Motility flagellar motor protein MotA experiment
FMIGHEMP_02290 VFG002358 Flagella 83.3 2.5e-86 1 186 0.9637 0.9637 Motility flagellar biosynthesis transcription activator FlhC experiment
FMIGHEMP_02291 VFG002359 Flagella 81 4.3e-46 1 116 1.0 1 Motility flagellar transcriptional activator FlhD experiment
FMIGHEMP_02356 VFG049018 RcsAB 88.9 1.1e-103 1 213 0.9771 0.9861 Regulation transcriptional regulator RcsB experiment
FMIGHEMP_02719 VFG013412 LOS 74.9 8.6e-134 2 304 0.9902 0.9934 Immune modulation UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase experiment
FMIGHEMP_02889 VFG000477 RpoS 79.9 2.2e-143 1 327 0.9939 0.9909 Regulation RNA polymerase sigma factor RpoS experiment
FMIGHEMP_03270 VFG001855 Hsp60 74.5 9.4e-224 1 548 1.0 0.9982 Adherence Hsp60, 60K heat shock protein HtpB experiment
FMIGHEMP_03445 VFG046465 EF-Tu 80.9 4e-192 1 393 0.9975 0.9975 Adherence elongation factor Tu experiment
FMIGHEMP_03638 VFG038365 T6SS 88.4 1.6e-92 1 172 1.0 1 Effector delivery system HcpA-like protein experiment
FMIGHEMP_00038 VFG013409 LOS 78.1 1.3e-141 1 310 0.9936 1.0065 Immune modulation ADP-L-glycero-D-mannoheptose-6-epimerase prediction
FMIGHEMP_00052 VFG048973 Capsule 79.4 3.4e-179 1 388 1.0 1 Immune modulation UDP-glucose 6-dehydrogenase prediction
FMIGHEMP_00128 VFG046459 EF-Tu 82.4 4.9e-194 1 393 0.9975 0.9975 Adherence elongation factor Tu prediction
FMIGHEMP_00199 VFG007640 Capsular polysaccharide 71.2 4.7e-154 2 369 0.9787 0.984 Immune modulation UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) prediction
FMIGHEMP_00201 VFG007659 Capsular polysaccharide 80.1 2.1e-172 3 353 0.9887 0.9643 Immune modulation dTDP-glucose 4,6-dehydratase prediction
FMIGHEMP_00202 VFG007661 Capsular polysaccharide 74.8 3.1e-129 1 286 0.9761 0.9565 Immune modulation glucose-1-phosphate thymidylyltransferase RfbA prediction
FMIGHEMP_00300 VFG013514 Exopolysaccharide 74.3 1.4e-192 1 444 0.9978 0.9978 Immune modulation phosphoglucosamine mutase prediction
FMIGHEMP_00696 VFG049146 AcrAB 76 0 1 1044 0.9924 0.9962 Antimicrobial activity/Competitive advantage acriflavine resistance protein B prediction
FMIGHEMP_00765 VFG013618 Heme biosynthesis 70.4 1.5e-183 1 426 0.9953 0.9861 Nutritional/Metabolic factor glutamate-1-semialdehyde 2,1-aminomutase prediction
FMIGHEMP_00783 VFG044280 Proteobactin 99.4 3.3e-189 1 360 1.0 1 Nutritional/Metabolic factor iron ABC transporter permease prediction
FMIGHEMP_00784 VFG044281 Proteobactin 99.2 5e-142 1 264 1.0 1 Nutritional/Metabolic factor ABC transporter ATP-binding protein prediction
FMIGHEMP_00785 VFG044282 Proteobactin 99.6 1.1e-158 1 278 1.0 1 Nutritional/Metabolic factor CoA ester lyase prediction
FMIGHEMP_00786 VFG044283 Proteobactin 98.9 0 1 626 1.0 0.9984 Nutritional/Metabolic factor IucA/IucC family siderophore biosynthesis protein prediction
FMIGHEMP_00787 VFG044284 Proteobactin 99.7 0 1 703 1.0 1 Nutritional/Metabolic factor TonB-dependent siderophore receptor prediction
FMIGHEMP_00788 VFG044285 Proteobactin 98.9 2.9e-278 1 467 1.0 1 Nutritional/Metabolic factor Y4yA family PLP-dependent enzyme prediction
FMIGHEMP_00789 VFG044286 Proteobactin 99.4 4.2e-194 1 338 1.0 1 Nutritional/Metabolic factor cysteine synthase family protein prediction
FMIGHEMP_00790 VFG044287 Proteobactin 98.4 9.2e-230 1 385 1.0 1 Nutritional/Metabolic factor NAD/NADP-dependent octopine/nopaline dehydrogenase family protein prediction
FMIGHEMP_00791 VFG044288 Proteobactin 99.8 1.2e-219 1 403 1.0 1 Nutritional/Metabolic factor MFS transporter prediction
FMIGHEMP_00792 VFG044289 Proteobactin 99.7 1.5e-221 1 375 1.0 1 Nutritional/Metabolic factor ABC transporter substrate-binding protein prediction
FMIGHEMP_00793 VFG044290 Proteobactin 100 9.1e-85 1 148 1.0 1 Nutritional/Metabolic factor ParB N-terminal domain-containing protein prediction
FMIGHEMP_00807 VFG042621 Proteus-like (MR/P) fimbriae, mannose resistant (biofilm formation) 78.9 1e-71 1 175 1.0 1 Adherence MR/P fimbria major subunit MrpA prediction
FMIGHEMP_00809 VFG042624 Proteus-like (MR/P) fimbriae, mannose resistant (biofilm formation) 74.6 7.4e-111 1 252 1.0 1 Adherence MR/P fimbria assembly chaperone MrpD prediction
FMIGHEMP_00815 VFG042620 Proteus-like (MR/P) fimbriae, mannose resistant (biofilm formation) 100 3e-109 1 188 1.0 1 Adherence phase variation DNA invertase MrpI prediction
FMIGHEMP_00816 VFG042621 Proteus-like (MR/P) fimbriae, mannose resistant (biofilm formation) 100 2.7e-91 1 175 1.0 1 Adherence MR/P fimbria major subunit MrpA prediction
FMIGHEMP_00817 VFG042622 Proteus-like (MR/P) fimbriae, mannose resistant (biofilm formation) 100 1.3e-101 5 186 0.9785 1 Adherence MR/P fimbria assembly terminator MrpB prediction
FMIGHEMP_00818 VFG042623 Proteus-like (MR/P) fimbriae, mannose resistant (biofilm formation) 99.9 0 1 871 1.0 1 Adherence MR/P fimbria usher protein MrpC prediction
FMIGHEMP_00819 VFG042624 Proteus-like (MR/P) fimbriae, mannose resistant (biofilm formation) 100 3.6e-142 1 252 1.0 1 Adherence MR/P fimbria assembly chaperone MrpD prediction
FMIGHEMP_00820 VFG042625 Proteus-like (MR/P) fimbriae, mannose resistant (biofilm formation) 100 1.9e-100 1 181 1.0 1 Adherence fimbrial protein prediction
FMIGHEMP_00821 VFG042626 Proteus-like (MR/P) fimbriae, mannose resistant (biofilm formation) 100 3e-89 1 161 1.0 1 Adherence fimbrial protein prediction
FMIGHEMP_00822 VFG042627 Proteus-like (MR/P) fimbriae, mannose resistant (biofilm formation) 100 1.5e-100 1 182 1.0 1 Adherence type 1 fimbrial protein prediction
FMIGHEMP_00823 VFG042628 Proteus-like (MR/P) fimbriae, mannose resistant (biofilm formation) 100 1.5e-157 1 275 1.0 1 Adherence MR/P fimbria adhesin subunit MrpH prediction
FMIGHEMP_00824 VFG042629 Proteus-like (MR/P) fimbriae, mannose resistant (biofilm formation) 100 1.8e-58 1 107 1.0 1 Adherence transcriptional regulator MrpJ prediction
FMIGHEMP_00832 VFG043807 ZapA 100 1.3e-292 1 491 1.0 1 Exotoxin serralysin family metalloprotease prediction
FMIGHEMP_00893 VFG013421 LOS 78.1 4.5e-84 1 192 1.0 0.9897 Immune modulation phosphoheptose isomerase prediction
FMIGHEMP_00920 VFG010906 CsrA 83.6 4.3e-20 1 55 0.8871 0.8594 Regulation carbon storage regulator CsrA prediction
FMIGHEMP_00928 VFG018243 AI-2 77.8 2e-75 1 171 1.0 0.9942 Biofilm S-ribosylhomocysteinase prediction
FMIGHEMP_00946 VFG049189 T6SS-II 83.9 0 1 857 0.9988 1 Effector delivery system ATP-dependent chaperone ClpB prediction
FMIGHEMP_01092 VFG042615 Uroepithelial cell adhesin (UCA) 99 2.9e-50 1 101 1.0 1 Adherence helix-turn-helix transcriptional regulator prediction
FMIGHEMP_01093 VFG042616 Uroepithelial cell adhesin (UCA) 99.7 1.8e-206 1 360 1.0 1 Adherence type 1 fimbrial protein prediction
FMIGHEMP_01094 VFG042617 Uroepithelial cell adhesin (UCA) 99.8 0 1 844 1.0 1 Adherence fimbrial biogenesis outer membrane usher protein prediction
FMIGHEMP_01095 VFG042618 Uroepithelial cell adhesin (UCA) 100 4.9e-136 1 241 1.0 1 Adherence fimbria/pilus periplasmic chaperone prediction
FMIGHEMP_01096 VFG042619 Uroepithelial cell adhesin (UCA) 100 2.6e-94 1 181 1.0 1 Adherence uroepithelial cell adherence major pilin UcaA prediction
FMIGHEMP_01101 VFG000478 Fur 86.4 2.5e-74 1 147 0.9932 0.98 Regulation ferric iron uptake transcriptional regulator prediction
FMIGHEMP_01217 VFG048844 Capsule 85.9 3.7e-233 1 468 1.0 1 Immune modulation NADP-dependent phosphogluconate dehydrogenase prediction
FMIGHEMP_01282 VFG038845 Polar flagella 70.9 1.5e-95 2 244 0.9605 0.9605 Motility NeuA protein prediction
FMIGHEMP_01308 VFG038380 T6SS 76.4 1.8e-230 1 492 1.0 1 Effector delivery system Type VI secretion system contractile sheath large subunit TssC/VipB prediction
FMIGHEMP_01310 VFG038370 T6SS 90.1 4.7e-93 1 172 1.0 1 Effector delivery system hemolysin co-regulated protein prediction
FMIGHEMP_01430 VFG038840 Polar flagella 77.5 2.3e-101 1 244 1.0 1 Motility short chain dehydrogenase/reductase family oxidoreductase prediction
FMIGHEMP_01671 VFG013466 LOS 80.6 9.2e-134 1 283 0.9965 0.9965 Immune modulation 2-dehydro-3-deoxyphosphooctonate aldolase prediction
FMIGHEMP_01700 VFG038370 T6SS 90.1 4.7e-93 1 172 1.0 1 Effector delivery system hemolysin co-regulated protein prediction
FMIGHEMP_01997 VFG044291 HmuR2 99.9 0 1 680 1.0 1 Nutritional/Metabolic factor TonB-dependent hemoglobin/transferrin/lactoferrin family receptor prediction
FMIGHEMP_01998 VFG044292 HmuR2 99.4 3.4e-199 1 349 1.0 1 Nutritional/Metabolic factor hemin-degrading factor prediction
FMIGHEMP_01999 VFG044293 HmuR2 100 3.4e-146 1 271 1.0 1 Nutritional/Metabolic factor hemin ABC transporter substrate-binding protein prediction
FMIGHEMP_02000 VFG044294 HmuR2 100 8.1e-174 9 334 0.976 1 Nutritional/Metabolic factor iron ABC transporter permease prediction
FMIGHEMP_02001 VFG044295 HmuR2 100 2.2e-150 1 264 1.0 1 Nutritional/Metabolic factor heme ABC transporter ATP-binding protein prediction
FMIGHEMP_02237 VFG002319 Flagella 83.5 6.2e-107 1 237 0.9875 0.9875 Motility flagellar biosynthesis sigma factor prediction
FMIGHEMP_02250 VFG002329 Flagella 81.7 2e-148 5 332 0.988 0.9939 Motility flagellar motor switch protein G prediction
FMIGHEMP_02252 VFG002331 Flagella 79.8 1.1e-202 1 451 0.9869 0.9934 Motility flagellum-specific ATP synthase FliI prediction
FMIGHEMP_02256 VFG002335 Flagella 79 1.1e-154 1 343 1.0 1.0269 Motility flagellar motor switch protein FliM prediction
FMIGHEMP_02259 VFG002338 Flagella 78.3 5.1e-99 18 256 0.9336 0.956 Motility flagellar biosynthetic protein FliP prediction
FMIGHEMP_02260 VFG002339 Flagella 77.5 1.6e-31 1 89 1.0 1 Motility flagellar biosynthetic protein FliQ prediction
FMIGHEMP_02266 VFG043029 Peritrichous flagella 76.5 1.3e-148 11 368 0.9728 0.9808 Motility flagellar biosynthesis protein FlgA prediction
FMIGHEMP_02267 VFG002345 Flagella 78.1 9.5e-95 29 247 0.8866 0.9202 Motility flagellar L-ring protein precursor FlgH prediction
FMIGHEMP_02268 VFG003433 Flagella 83.5 1.6e-121 1 260 1.0 1 Motility flagellar basal-body rod protein FlgG prediction
FMIGHEMP_02272 VFG002679 Flagella 77.6 9.8e-54 1 134 1.0 1 Motility flagellar basal-body rod protein FlgC prediction
FMIGHEMP_02278 VFG023690 Flagella 78 4.3e-302 1 692 0.9943 1 Motility flagellar biosynthesis protein FlhA prediction
FMIGHEMP_02280 VFG043205 Flagella 74.1 2.2e-79 7 218 0.9725 0.9907 Motility chemotaxis regulator CheZ prediction
FMIGHEMP_02281 VFG043206 Flagella 83.7 2.7e-56 1 129 1.0 1 Motility chemotaxis regulatory protein CheY prediction
FMIGHEMP_02282 VFG043038 Peritrichous flagella 76.6 7.3e-149 1 350 1.0 1.0029 Motility chemotaxis response regulator protein-glutamate methylesterase prediction
FMIGHEMP_02286 VFG043210 Flagella 81 2e-64 8 160 0.9217 0.9273 Motility purine-binding chemotaxis protein CheW prediction
FMIGHEMP_02289 VFG043213 Flagella 70.6 2.6e-112 1 289 1.0 0.9797 Motility flagellar motor protein MotA prediction
FMIGHEMP_02290 VFG002687 Flagella 82.8 1.1e-85 1 186 0.9637 0.9637 Motility flagellar biosynthesis transcription activator FlhC prediction
FMIGHEMP_02291 VFG002359 Flagella 81 3.2e-45 1 116 1.0 1 Motility flagellar transcriptional activator FlhD prediction
FMIGHEMP_02356 VFG049010 RcsAB 90.5 3.8e-103 1 210 0.9633 0.9722 Regulation transcriptional regulator RcsB prediction
FMIGHEMP_02520 VFG042610 PMF pili 100 4.2e-95 1 184 1.0 1 Adherence fimbrial protein prediction
FMIGHEMP_02521 VFG042611 PMF pili 100 0 1 828 1.0 1 Adherence fimbria/pilus outer membrane usher protein prediction
FMIGHEMP_02522 VFG042612 PMF pili 100 1.8e-144 1 254 1.0 1 Adherence molecular chaperone prediction
FMIGHEMP_02523 VFG042613 PMF pili 99.4 7.5e-210 1 357 1.0 1 Adherence fimbrial protein prediction
FMIGHEMP_02524 VFG042614 PMF pili 99.5 1.2e-97 1 182 1.0 1 Adherence type 1 fimbrial protein prediction
FMIGHEMP_02712 VFG042330 HpmA-HpmB 99.6 0 1 561 1.0 1 Effector delivery system hemolysin secretion/activation protein HpmB prediction
FMIGHEMP_02713 VFG042331 HpmA-HpmB 99.6 0 1 1577 1.0 1 Effector delivery system calcium-independent hemolysin HpmA prediction
FMIGHEMP_02719 VFG013417 LOS 73.4 4.4e-134 2 305 0.9935 0.9967 Immune modulation UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase prediction
FMIGHEMP_02774 VFG042332 AipA 98.8 4e-133 1 251 1.0 1 Effector delivery system trimeric autotransporter adhesin AipA prediction
FMIGHEMP_02889 VFG000477 RpoS 79.9 1.6e-142 1 327 0.9939 0.9909 Regulation RNA polymerase sigma factor RpoS prediction
FMIGHEMP_02999 VFG042333 Proteus toxic agglutinin (Pta) 99.5 0 1 1084 1.0 1 Effector delivery system autotransporter Pta prediction
FMIGHEMP_03015 VFG013435 LOS 70.4 8e-191 8 473 0.9831 0.979 Immune modulation ADP-heptose synthase prediction
FMIGHEMP_03270 VFG045692 Hsp60 73.5 2.4e-223 1 548 1.0 0.9946 Adherence Hsp60, 60K heat shock protein HtpB prediction
FMIGHEMP_03401 VFG013531 Exopolysaccharide 77.6 8.7e-258 1 548 1.0 0.9982 Immune modulation glucose-6-phosphate isomerase prediction
FMIGHEMP_03427 VFG013200 Heme biosynthesis 78 1.9e-165 1 354 0.9916 1 Nutritional/Metabolic factor uroporphyrinogen decarboxylase prediction
FMIGHEMP_03445 VFG046459 EF-Tu 82.4 4.9e-194 1 393 0.9975 0.9975 Adherence elongation factor Tu prediction
FMIGHEMP_03638 VFG038370 T6SS 89 3.1e-92 1 172 1.0 1 Effector delivery system hemolysin co-regulated protein prediction







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group
FMIGHEMP_00059 Hydrogen Peroxide (H2O2) [class: Peroxides], Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)], Chlorhexidine [class: Biguanides] 79 4.9e-213 1 452 0.9762 0.9891 experiment
FMIGHEMP_00060 Hydrogen Peroxide (H2O2) [class: Peroxides], Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)], Chlorhexidine [class: Biguanides] 87 6.4e-113 1 230 0.9914 0.9914 experiment
FMIGHEMP_00077 Antimony (Sb), Arsenic (As), Glycerol [class: Alcohol] 70.9 2.2e-112 1 268 0.9889 0.9537 experiment
FMIGHEMP_00107 Hydrogen Peroxide (H2O2) [class: Peroxides], Sodium Deoxycholate (SDC) [class: Acid], Acriflavine [class: Acridine], Rhodamine 6G [class: Xanthene], Ethidium Bromide [class: Phenanthridine], Sodium Dodecyl Sulfate (SDS) [class: Organo-sulfate] 81.9 6.6e-142 1 298 0.9770 0.9770 experiment
FMIGHEMP_00436 Cetrimide (CTM) [class: Quaternary Ammonium Compounds (QACs)], Cetylpyridinium Chloride (CPC) [class: Quaternary Ammonium Compounds (QACs)], Tetraphenylphosphonium (TPP) [class: Quaternary Ammonium Compounds (QACs)], Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)], Ethidium Bromide [class: Phenanthridine], Sodium Dodecyl Sulfate (SDS) [class: Organo-sulfate] 75 9.5e-40 1 104 1.0000 0.9905 experiment
FMIGHEMP_00696 Acriflavine [class: Acridine], Phenol [class: Phenolic compounds], Triclosan [class: Phenolic compounds], p-xylene [class: Aromatic hydrocarbons], Cyclohexane [class: Cycloalkane], Pentane [class: Alkane] 76.1 0 1 1044 0.9933 0.9962 experiment
FMIGHEMP_00825 Triton X-100 [class: Polyethylene glycol] 71.2 9.4e-213 2 519 0.9885 0.9719 experiment
FMIGHEMP_00958 Phenylmercury Acetate [class: Organo-mercury], 2-Chlorophenylhydrazine [class: Hydrazine], Carbonylcyanide m-chlorophenyl hydrazone (CCCP) [class: Hydrazone] 72.7 2e-223 3 504 0.9941 0.9805 experiment
FMIGHEMP_01001 Cobalt (Co), Magnesium (Mg) 84.1 4.3e-138 1 289 0.9898 0.9932 experiment
FMIGHEMP_01160 Tungsten (W), Molybdenum (Mo) 76.2 3e-94 1 227 0.9870 0.9913 experiment
FMIGHEMP_01614 Iron (Fe), Manganese (Mn) 82.1 2.2e-121 1 279 0.9208 0.9490 experiment
FMIGHEMP_01615 Iron (Fe), Manganese (Mn) 77.4 7.4e-130 6 293 0.9763 0.9730 experiment
FMIGHEMP_01616 Iron (Fe), Manganese (Mn) 75.4 4.4e-130 10 302 0.9702 0.9421 experiment
FMIGHEMP_01699 Chromium (Cr), Tellurium (Te), Selenium (Se) 75.1 4.3e-142 1 329 0.9792 0.9347 experiment
FMIGHEMP_01712 Zinc (Zn) 78.1 5.2e-103 1 256 0.9808 0.9808 experiment
FMIGHEMP_01713 Zinc (Zn) 74.7 3.1e-102 1 237 0.9834 0.9442 experiment
FMIGHEMP_01721 Sodium Deoxycholate (SDC) [class: Acid], Sodium Dodecyl Sulfate (SDS) [class: Organo-sulfate], Spermidine [class: Polyamines] 70.6 1.1e-38 2 110 0.9909 1.0000 experiment
FMIGHEMP_01736 Iron (Fe), Hydrogen Peroxide (H2O2) [class: Peroxides] 71 1e-95 1 252 0.9844 0.9730 experiment
FMIGHEMP_01953 Triclosan [class: Phenolic compounds] 86.3 1e-130 1 262 1.0000 1.0000 experiment
FMIGHEMP_01967 Chlorhexidine [class: Biguanides] 78.6 2e-91 1 192 1.0000 0.8571 experiment
FMIGHEMP_01967 Selenium (Se), Hydrogen Peroxide (H2O2) [class: Peroxides] 78.6 2e-91 1 192 1.0000 0.8571 experiment
FMIGHEMP_01977 Hydrochloric acid (HCl) [class: Acid] 76.7 3.3e-218 1 508 0.9865 0.9980 experiment
FMIGHEMP_02084 Acriflavine [class: Acridine], Ethidium Bromide [class: Phenanthridine], Methyl Viologen [class: Paraquat], Chlorhexidine [class: Biguanides] 73.6 1.1e-38 1 110 1.0000 1.0000 experiment
FMIGHEMP_02204 Zinc (Zn) 75.5 0 6 1033 0.9895 0.9923 experiment
FMIGHEMP_02205 Sodium Deoxycholate (SDC) [class: Acid] 72.8 0 1 1018 0.9912 0.9932 experiment
FMIGHEMP_02310 Sodium Deoxycholate (SDC) [class: Acid] 72 1.9e-160 9 397 0.9677 0.9534 experiment
FMIGHEMP_02802 Arsenic (As), Antimony (Sb) 82.4 4.6e-197 1 426 0.9930 0.9930 experiment
FMIGHEMP_02827 Copper (Cu) 72.7 0 140 984 0.8587 1.0132 experiment
FMIGHEMP_02889 Hydrochloric acid (HCl) [class: Acid], Sodium hydroxide (NaOH) [class: Base] 79.9 5.8e-144 1 327 1.0000 0.9970 experiment
FMIGHEMP_03048 Tellurium (Te) 81.7 3.5e-88 1 191 1.0000 1.0000 experiment
FMIGHEMP_03049 Tellurium (Te) 92.2 6.7e-100 1 192 1.0000 1.0000 experiment
FMIGHEMP_03050 Tellurium (Te) 87.6 3e-167 1 338 0.9912 0.9769 experiment
FMIGHEMP_03051 Tellurium (Te) 81.4 5.4e-52 1 118 0.7815 0.9672 experiment
FMIGHEMP_03053 Tellurium (Te) 73.7 1.2e-83 1 194 1.0000 1.0052 experiment
FMIGHEMP_03129 Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)], Ethidium Bromide [class: Phenanthridine], Acriflavine [class: Acridine], Chlorhexidine [class: Biguanides], Pyronin Y [class: Xanthene], Rhodamine 6G [class: Xanthene], Methyl Viologen [class: Paraquat], Tetraphenylphosphonium (TPP) [class: Quaternary Ammonium Compounds (QACs)], 4,6-diamidino-2-phenylindole (DAPI) [class: Diamindine], Acridine Orange [class: Acridine], Sodium Dodecyl Sulfate (SDS) [class: Organo-sulfate], Sodium Deoxycholate (SDC) [class: Acid], Crystal Violet [class: Triarylmethane], Cetrimide (CTM) [class: Quaternary Ammonium Compounds (QACs)], Cetylpyridinium Chloride (CPC) [class: Quaternary Ammonium Compounds (QACs)], Dequalinium [class: Quaternary Ammonium Compounds (QACs)] 100 1.1e-60 1 115 1.0000 1.0000 experiment
FMIGHEMP_03354 Vanadium (V), Triclosan [class: Phenolic compounds] 77.1 0 1 1021 0.9961 0.9922 experiment
FMIGHEMP_03543 Arsenic (As) 77.5 1.7e-157 1 346 1.0000 1.0000 experiment
FMIGHEMP_03544 Arsenic (As) 85.3 4.8e-151 1 319 1.0000 1.0000 experiment
FMIGHEMP_03545 Arsenic (As) 82.9 8.2e-137 9 300 0.9767 0.9899 experiment
FMIGHEMP_03546 Arsenic (As) 92.1 2.1e-136 6 258 0.9806 0.9844 experiment
FMIGHEMP_03659 Zinc (Zn), Tellurium (Te) 72.3 4.3e-202 14 509 0.9746 1.0000 experiment
FMIGHEMP_03683 Selenium (Se), Hydrogen Peroxide (H2O2) [class: Peroxides] 77.2 2.4e-95 1 206 0.9952 1.0000 experiment
FMIGHEMP_03686 Sodium Glycocholate [class: Acid], Sodium acetate [class: Acetate] 80.3 2.1e-234 20 551 0.9655 0.9690 experiment
FMIGHEMP_00059 Hydrogen Peroxide (H2O2) [class: Peroxides], Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)], Chlorhexidine [class: Biguanides] 80.5 2.4e-213 1 452 0.9762 0.9891 prediction
FMIGHEMP_00060 Hydrogen Peroxide (H2O2) [class: Peroxides], Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)], Chlorhexidine [class: Biguanides] 100 5.4e-129 1 232 1.0000 1.0000 prediction
FMIGHEMP_00077 Antimony (Sb), Arsenic (As), Glycerol [class: Alcohol] 72.4 1.1e-112 1 271 1.0037 0.9645 prediction
FMIGHEMP_00107 Hydrogen Peroxide (H2O2) [class: Peroxides], Sodium Deoxycholate (SDC) [class: Acid], Acriflavine [class: Acridine], Rhodamine 6G [class: Xanthene], Ethidium Bromide [class: Phenanthridine], Sodium Dodecyl Sulfate (SDS) [class: Organo-sulfate] 84.2 6e-144 1 298 0.9770 0.9770 prediction
FMIGHEMP_00158 Zinc (Zn) 75.2 1.4e-55 1 137 1.0000 0.9580 prediction
FMIGHEMP_00436 Cetrimide (CTM) [class: Quaternary Ammonium Compounds (QACs)], Cetylpyridinium Chloride (CPC) [class: Quaternary Ammonium Compounds (QACs)], Tetraphenylphosphonium (TPP) [class: Quaternary Ammonium Compounds (QACs)], Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)], Ethidium Bromide [class: Phenanthridine], Sodium Dodecyl Sulfate (SDS) [class: Organo-sulfate] 75 5.7e-38 1 104 1.0000 0.9905 prediction
FMIGHEMP_00696 Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)], Chlorhexidine [class: Biguanides], Triclosan [class: Phenolic compounds], Sodium Dodecyl Sulfate (SDS) [class: Organo-sulfate], Acriflavine [class: Acridine], Rhodamine 6G [class: Xanthene] 77.4 0 1 1044 0.9924 0.9962 prediction
FMIGHEMP_00802 Palmitic acid [class: Free Fatty Acids] 93.1 1e-69 1 145 1.0000 1.0000 prediction
FMIGHEMP_00825 Triton X-100 [class: Polyethylene glycol] 100 3.3e-291 1 524 1.0000 1.0000 prediction
FMIGHEMP_00929 Cobalt (Co), Magnesium (Mg) 72.1 3.7e-176 1 423 0.9976 0.9883 prediction
FMIGHEMP_00958 Phenylmercury Acetate [class: Organo-mercury], 2-Chlorophenylhydrazine [class: Hydrazine], Carbonylcyanide m-chlorophenyl hydrazone (CCCP) [class: Hydrazone] 74.7 1.6e-223 3 504 0.9941 0.9805 prediction
FMIGHEMP_00963 Carbonyl cyanide 3-chlorophenylhydrazone (CCCP) [class: Hydrazone] 83.6 3.2e-73 1 171 0.9771 1.0000 prediction
FMIGHEMP_01001 Cobalt (Co), Magnesium (Mg) 100 2.2e-164 1 293 1.0000 1.0000 prediction
FMIGHEMP_01160 Tungsten (W), Molybdenum (Mo) 86.3 1.1e-105 1 227 0.9870 0.9913 prediction
FMIGHEMP_01455 Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)], Chlorhexidine [class: Biguanides] 73.1 5.4e-94 1 223 0.9955 1.0000 prediction
FMIGHEMP_01594 Iron (Fe), Copper (Cu), Manganese (Mn) 77.8 1.3e-71 1 167 1.0000 1.0000 prediction
FMIGHEMP_01613 Iron (Fe), Manganese (Mn) 100 5.7e-149 1 285 1.0000 1.0000 prediction
FMIGHEMP_01614 Iron (Fe), Manganese (Mn) 100 1.5e-158 1 303 1.0000 1.0000 prediction
FMIGHEMP_01615 Iron (Fe), Manganese (Mn) 100 1.4e-169 1 295 1.0000 1.0000 prediction
FMIGHEMP_01616 Iron (Fe), Manganese (Mn) 93.3 8.2e-154 18 302 0.9437 1.0000 prediction
FMIGHEMP_01699 Chromium (Cr), Tellurium (Te), Selenium (Se) 77.2 9.5e-143 1 329 0.9792 0.9347 prediction
FMIGHEMP_01712 Zinc (Zn) 80.4 6.7e-104 1 255 0.9770 0.9770 prediction
FMIGHEMP_01713 Zinc (Zn) 76.4 2e-102 1 237 0.9834 0.9442 prediction
FMIGHEMP_01720 Sodium Dodecyl Sulfate (SDS) [class: Organo-sulfate], Sodium Deoxycholate (SDC) [class: Acid], Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)], Chlorhexidine [class: Biguanides], Triclosan [class: Phenolic compounds], Methyl Viologen [class: Paraquat], Hydrogen Peroxide (H2O2) [class: Peroxides] 78.5 2.6e-36 1 107 0.7329 0.8560 prediction
FMIGHEMP_01721 Sodium Deoxycholate (SDC) [class: Acid], Sodium Dodecyl Sulfate (SDS) [class: Organo-sulfate], Spermidine [class: Polyamines] 100 3.2e-55 1 110 1.0000 1.0000 prediction
FMIGHEMP_01736 Iron (Fe), Hydrogen Peroxide (H2O2) [class: Peroxides] 72.9 3.4e-100 1 255 0.9961 0.9922 prediction
FMIGHEMP_01953 Triclosan [class: Phenolic compounds] 100 4.6e-145 1 262 1.0000 1.0000 prediction
FMIGHEMP_01967 Hydrogen Peroxide (H2O2) [class: Peroxides] 84.4 3.4e-97 1 192 1.0000 1.0000 prediction
FMIGHEMP_01977 Hydrochloric acid (HCl) [class: Acid] 100 2.1e-282 1 517 1.0000 1.0000 prediction
FMIGHEMP_02084 Acriflavine [class: Acridine], Ethidium Bromide [class: Phenanthridine], Methyl Viologen [class: Paraquat], Chlorhexidine [class: Biguanides] 73.6 1.3e-37 1 110 1.0000 1.0000 prediction
FMIGHEMP_02204 Zinc (Zn) 76 0 6 1033 0.9895 0.9923 prediction
FMIGHEMP_02205 Sodium Deoxycholate (SDC) [class: Acid] 73.2 0 1 1018 0.9912 0.9932 prediction
FMIGHEMP_02310 Sodium Deoxycholate (SDC) [class: Acid] 72.8 1.8e-164 9 402 0.9801 0.9471 prediction
FMIGHEMP_02714 Copper (Cu) 70.2 0 7 826 0.9903 0.9751 prediction
FMIGHEMP_02802 Arsenic (As), Antimony (Sb) 83.1 2.2e-197 1 427 0.9953 0.9953 prediction
FMIGHEMP_02826 Copper (Cu) 72.7 1.2e-51 1 132 0.9925 0.9706 prediction
FMIGHEMP_02827 Copper (Cu), Silver (Ag) 73.1 0 140 984 0.8587 1.0132 prediction
FMIGHEMP_02889 Hydrochloric acid (HCl) [class: Acid], Sodium hydroxide (NaOH) [class: Base] 80.5 3.2e-143 1 327 1.0000 0.9970 prediction
FMIGHEMP_02907 Cetrimide (CTM) [class: Quaternary Ammonium Compounds (QACs)], Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)], Hoechst 33342 [class: Bisbenzimide], Ethidium Bromide [class: Phenanthridine], Rhodamine 6G [class: Xanthene], Acriflavine [class: Acridine], Tetraphenylphosphonium (TPP) [class: Quaternary Ammonium Compounds (QACs)], Chlorhexidine [class: Biguanides], Crystal Violet [class: Triarylmethane], Dequalinium [class: Quaternary Ammonium Compounds (QACs)], Pentamidine [class: Diamidine], Pyronin Y [class: Xanthene] 100 7e-230 1 393 1.0000 1.0000 prediction
FMIGHEMP_02995 Cobalt (Co), Magnesium (Mg) 100 5.9e-66 1 125 1.0000 1.0000 prediction
FMIGHEMP_03048 Tellurium (Te) 83.8 2.5e-87 1 191 1.0000 1.0000 prediction
FMIGHEMP_03049 Tellurium (Te) 100 1e-104 1 192 1.0000 1.0000 prediction
FMIGHEMP_03050 Tellurium (Te) 88.5 1.3e-168 1 338 0.9912 0.9769 prediction
FMIGHEMP_03051 Tellurium (Te) 82.1 3.6e-65 1 151 1.0000 1.0000 prediction
FMIGHEMP_03053 Tellurium (Te) 74.7 6.4e-83 1 194 1.0000 1.0052 prediction
FMIGHEMP_03274 Copper (Cu) 83.1 2.3e-168 1 397 0.9002 0.7972 prediction
FMIGHEMP_03354 Vanadium (V), Triclosan [class: Phenolic compounds] 77.3 0 1 1021 0.9961 0.9922 prediction
FMIGHEMP_03407 Sodium acetate [class: Acetate] 72.2 1.2e-106 8 277 0.9712 0.9818 prediction
FMIGHEMP_03543 Arsenic (As) 81.5 4.5e-164 1 346 1.0000 1.0000 prediction
FMIGHEMP_03544 Arsenic (As) 91.2 5.3e-159 1 317 0.9937 0.9969 prediction
FMIGHEMP_03545 Arsenic (As) 88.3 5.7e-139 17 299 0.9433 0.9659 prediction
FMIGHEMP_03546 Arsenic (As) 99.2 4.9e-147 1 258 1.0000 1.0000 prediction
FMIGHEMP_03659 Zinc (Zn), Tellurium (Te) 78.1 1.6e-221 1 509 1.0000 1.0000 prediction
FMIGHEMP_03683 Selenium (Se), Hydrogen Peroxide (H2O2) [class: Peroxides] 79.1 2.3e-99 1 206 0.9952 0.9952 prediction
FMIGHEMP_03686 Copper (Cu), Sodium acetate [class: Acetate] 79.5 1.7e-242 1 551 1.0018 1.0000 prediction






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism
FMIGHEMP_00004 ARO:3003306 84.6 0 1 804 1.0000 1.0000 fluoroquinolone antibiotic fluoroquinolone resistant gyrB antibiotic target alteration
FMIGHEMP_00052 ARO:3003577 76.3 2.26e-221 1 388 1.0000 1.0000 peptide antibiotic pmr phosphoethanolamine transferase antibiotic target alteration
FMIGHEMP_00059 ARO:3000830 79 4.3e-267 1 452 0.9762 0.9891 aminoglycoside antibiotic resistance-nodulation-cell division (RND) antibiotic efflux pump antibiotic efflux
FMIGHEMP_00128 ARO:3003368 94.9 3.83e-278 1 394 1.0000 1.0000 elfamycin antibiotic elfamycin resistant EF-Tu antibiotic target alteration
FMIGHEMP_00131 ARO:3003930 70.6 5.12e-46 1 102 0.9903 0.9903 tetracycline antibiotic tetracycline-resistant ribosomal protection protein antibiotic target protection
FMIGHEMP_00218 ARO:3003900 77.4 0 1 836 0.9699 0.9894 phosphonic acid antibiotic antibiotic-resistant cya adenylate cyclase antibiotic target alteration
FMIGHEMP_00299 ARO:3003386 73.7 6.1e-147 1 278 0.9929 0.9858 sulfonamide antibiotic sulfonamide resistant dihydropteroate synthase folP antibiotic target alteration
FMIGHEMP_00443 ARO:3003889 85.7 8.63e-297 1 448 0.9956 0.9912 phosphonic acid antibiotic antibiotic-resistant GlpT antibiotic target alteration
FMIGHEMP_00509 ARO:3005041 80 3.32e-150 7 266 0.9630 0.9665 oxazolidinone antibiotic ATP-binding cassette (ABC) antibiotic efflux pump antibiotic efflux
FMIGHEMP_00515 ARO:3003775 85.1 2.75e-261 1 416 0.9905 0.9928 phosphonic acid antibiotic antibiotic-resistant murA transferase antibiotic target alteration
FMIGHEMP_00696 ARO:3000216 76.1 0 1 1044 0.9933 0.9962 fluoroquinolone antibiotic resistance-nodulation-cell division (RND) antibiotic efflux pump antibiotic efflux
FMIGHEMP_00920 ARO:3005069 93 1.47e-31 1 57 0.9194 0.9344 fluoroquinolone antibiotic resistance-nodulation-cell division (RND) antibiotic efflux pump antibiotic efflux
FMIGHEMP_00958 ARO:3004597 72.7 1.7e-279 3 504 0.9941 0.9805 macrolide antibiotic major facilitator superfamily (MFS) antibiotic efflux pump antibiotic efflux
FMIGHEMP_01278 ARO:3003950 80.3 0 2 581 0.9983 0.9966 nitroimidazole antibiotic ATP-binding cassette (ABC) antibiotic efflux pump antibiotic efflux
FMIGHEMP_01288 ARO:3004657 96.8 7.24e-160 1 217 1.0000 1.0000 phenicol antibiotic chloramphenicol acetyltransferase (CAT) antibiotic inactivation
FMIGHEMP_01352 ARO:3005044 71.1 3.6e-175 1 360 0.9945 0.9626 peptide antibiotic General Bacterial Porin with reduced permeability to peptide antibiotics reduced permeability to antibiotic
FMIGHEMP_01430 ARO:3004049 85.7 7.76e-141 1 244 1.0000 1.0000 disinfecting agents and antiseptics antibiotic resistant fabG antibiotic target alteration
FMIGHEMP_01633 ARO:3003578 74.7 3.4e-170 7 314 0.9448 0.9565 peptide antibiotic pmr phosphoethanolamine transferase antibiotic target alteration
FMIGHEMP_01682 ARO:3001216 73.4 4.95e-213 1 398 0.9950 0.9900 fluoroquinolone antibiotic major facilitator superfamily (MFS) antibiotic efflux pump antibiotic efflux
FMIGHEMP_01720 ARO:3004580 72.9 3.69e-44 1 107 0.7329 0.8917 macrolide antibiotic small multidrug resistance (SMR) antibiotic efflux pump antibiotic efflux
FMIGHEMP_01721 ARO:3004583 70.1 3.62e-49 4 110 0.9727 0.9817 macrolide antibiotic small multidrug resistance (SMR) antibiotic efflux pump antibiotic efflux
FMIGHEMP_01953 ARO:3004045 86.3 1.82e-164 1 262 1.0000 1.0000 disinfecting agents and antiseptics antibiotic resistant fabI antibiotic target alteration
FMIGHEMP_02057 ARO:3000676 77 8.96e-62 1 134 1.0075 0.9854 macrolide antibiotic major facilitator superfamily (MFS) antibiotic efflux pump antibiotic efflux
FMIGHEMP_02204 ARO:3000793 75.9 0 6 1028 0.9808 0.9837 aminocoumarin antibiotic resistance-nodulation-cell division (RND) antibiotic efflux pump antibiotic efflux
FMIGHEMP_02205 ARO:3000794 72.1 0 1 1018 0.9912 0.9932 aminocoumarin antibiotic resistance-nodulation-cell division (RND) antibiotic efflux pump antibiotic efflux
FMIGHEMP_02310 ARO:3001329 72 5.96e-202 9 397 0.9677 0.9534 phosphonic acid antibiotic major facilitator superfamily (MFS) antibiotic efflux pump antibiotic efflux
FMIGHEMP_02358 ARO:3003926 84.3 0 1 853 0.9726 0.9715 fluoroquinolone antibiotic fluoroquinolone resistant gyrA antibiotic target alteration
FMIGHEMP_02472 ARO:3003899 77.9 8.97999884042966e-318 1 575 1.0000 1.0000 phosphonic acid antibiotic antibiotic-resistant ptsI phosphotransferase antibiotic target alteration
FMIGHEMP_02731 ARO:3007421 76.4 0 18 598 0.9716 0.9881 cephalosporin Penicillin-binding protein mutations conferring resistance to beta-lactam antibiotics antibiotic target alteration
FMIGHEMP_03003 ARO:3003316 81.9 0 1 631 1.0000 1.0016 fluoroquinolone antibiotic fluoroquinolone resistant parE antibiotic target alteration
FMIGHEMP_03064 ARO:3000177 98.7 1.63e-281 1 398 1.0000 1.0000 tetracycline antibiotic major facilitator superfamily (MFS) antibiotic efflux pump antibiotic efflux
FMIGHEMP_03118 ARO:3002602 100 5.68e-187 1 259 1.0000 1.0000 aminoglycoside antibiotic ANT(3'') antibiotic inactivation
FMIGHEMP_03119 ARO:3000361 98.8 1.72e-287 1 406 1.0000 1.0000 macrolide antibiotic macrolide esterase antibiotic inactivation
FMIGHEMP_03120 ARO:3004555 100 2.32e-113 1 157 1.0000 1.0000 diaminopyrimidine antibiotic trimethoprim resistant dihydrofolate reductase dfr antibiotic target replacement
FMIGHEMP_03128 ARO:3000410 99.6 4.87e-198 1 279 1.0000 1.0000 sulfonamide antibiotic sulfonamide resistant sul antibiotic target replacement
FMIGHEMP_03129 ARO:3005010 100 2.01e-78 1 115 1.0000 1.0000 disinfecting agents and antiseptics major facilitator superfamily (MFS) antibiotic efflux pump antibiotic efflux
FMIGHEMP_03130 ARO:3002848 100 4.06e-115 1 150 1.0000 1.0000 rifamycin antibiotic rifampin ADP-ribosyltransferase (Arr) antibiotic inactivation
FMIGHEMP_03131 ARO:3002676 100 7.29e-161 1 210 1.0000 1.0000 phenicol antibiotic chloramphenicol acetyltransferase (CAT) antibiotic inactivation
FMIGHEMP_03132 ARO:3001396 100 6.06e-199 16 291 0.9485 1.0000 cephalosporin OXA beta-lactamase antibiotic inactivation
FMIGHEMP_03133 ARO:3002581 98 1.4e-140 2 199 0.9950 0.9754 aminoglycoside antibiotic AAC(6') antibiotic inactivation
FMIGHEMP_03135 ARO:3002539 100 8.8e-195 1 258 1.0000 1.0000 aminoglycoside antibiotic AAC(3) antibiotic inactivation
FMIGHEMP_03137 ARO:3002655 100 1.82e-256 1 341 1.0000 1.0000 aminoglycoside antibiotic APH(4) antibiotic inactivation
FMIGHEMP_03144 ARO:3000412 100 6.4e-186 12 282 0.9610 1.0000 sulfonamide antibiotic sulfonamide resistant sul antibiotic target replacement
FMIGHEMP_03147 ARO:3002705 99.3 1.32e-274 1 404 1.0000 1.0000 phenicol antibiotic major facilitator superfamily (MFS) antibiotic efflux pump antibiotic efflux
FMIGHEMP_03156 ARO:3001926 100 6.93e-204 1 291 1.0000 1.0000 cephalosporin CTX-M beta-lactamase antibiotic inactivation
FMIGHEMP_03161 ARO:3002641 98.5 6.49e-208 1 271 1.0000 1.0000 aminoglycoside antibiotic APH(3') antibiotic inactivation
FMIGHEMP_03164 ARO:3000167 99.5 8.27e-274 1 396 1.0000 1.0000 tetracycline antibiotic major facilitator superfamily (MFS) antibiotic efflux pump antibiotic efflux
FMIGHEMP_03206 ARO:3000412 100 4.11e-186 1 271 1.0000 1.0000 sulfonamide antibiotic sulfonamide resistant sul antibiotic target replacement
FMIGHEMP_03207 ARO:3002639 99.6 5.98e-202 1 267 1.0000 1.0000 aminoglycoside antibiotic APH(3'') antibiotic inactivation
FMIGHEMP_03208 ARO:3002660 99.6 1.07e-205 1 278 1.0000 1.0000 aminoglycoside antibiotic APH(6) antibiotic inactivation
FMIGHEMP_03354 ARO:3000808 77.2 0 1 1019 0.9941 0.9903 fluoroquinolone antibiotic resistance-nodulation-cell division (RND) antibiotic efflux pump antibiotic efflux
FMIGHEMP_03438 ARO:3003288 93.4 0 1 1342 1.0000 1.0000 rifamycin antibiotic rifamycin-resistant beta-subunit of RNA polymerase (rpoB) antibiotic target alteration
FMIGHEMP_03445 ARO:3003368 94.9 3.83e-278 1 394 1.0000 1.0000 elfamycin antibiotic elfamycin resistant EF-Tu antibiotic target alteration
FMIGHEMP_03473 ARO:3000518 98.1 8.12e-149 1 210 1.0000 1.0000 macrolide antibiotic resistance-nodulation-cell division (RND) antibiotic efflux pump antibiotic efflux
FMIGHEMP_03724 ARO:3002854 99.4 2.81e-114 1 157 1.0000 1.0000 diaminopyrimidine antibiotic trimethoprim resistant dihydrofolate reductase dfr antibiotic target replacement






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant
FMIGHEMP_00015 PHI:8576 pyrE (Dda3937_03258) 77 6.1e-93 1 213 0.9953 1.0000 eudicots soft rot orotate phosphoribosyl transferase reduced virulence
FMIGHEMP_00059 PHI:8513 cpxA 79 3.1e-211 1 452 0.9762 0.9891 rodents colitis two-component sensor kinase loss of pathogenicity
FMIGHEMP_00060 PHI:8512 cpxR 87.8 4.4e-113 1 230 0.9914 0.9914 rodents colitis two-component response regulator loss of pathogenicity
FMIGHEMP_00069 PHI:9309 pfkA 83.2 2.8e-158 5 325 0.9877 0.9969 eudicots fire blight ATP-dependent 6-phosphofructokinase reduced virulence
FMIGHEMP_00088 PHI:2695 metJ 91.4 1.1e-52 1 105 1.0000 1.0000 eudicots tuber rot; blackleg disease repressor of the methionine biosynthesis regulon reduced virulence
FMIGHEMP_00093 PHI:9322 ppc 74.5 0 1 878 1.0000 1.0000 eudicots fire blight phosphoenolpyruvate carboxylase unaffected pathogenicity
FMIGHEMP_00105 PHI:9316 argG 83.3 6.3e-200 3 403 0.9950 0.9926 eudicots fire blight argininosuccinate synthase reduced virulence
FMIGHEMP_00107 PHI:3092 SoxR 81.2 2.2e-141 1 298 0.9770 0.9770 monocots Stewart's wilt activate gene expression in response to oxidative stress reduced virulence
FMIGHEMP_00128 PHI:10282 tufA 75.8 6e-179 1 393 0.9975 0.9975 primates skin infection; food poisoning; respiratory disease elongation factor Tu increased virulence (hypervirulence)
FMIGHEMP_00142 PHI:11120 rplN 74 2.7e-45 1 123 1.0000 1.0000 primates pertussis 50S ribosomal protein unaffected pathogenicity
FMIGHEMP_00185 PHI:9318 ilvA 79 1.1e-239 1 515 0.9828 0.9981 eudicots fire blight threonine dehydratase reduced virulence
FMIGHEMP_00195 PHI:2644 thioredoxin 1 82.4 4.2e-50 1 108 1.0000 0.9908 nematodes food poisoning redox activity reduced virulence
FMIGHEMP_00197 PHI:4074 wecA 79.6 2.3e-161 1 353 0.9860 0.9289 moths hemolymph bleeding virulence factor reduced virulence
FMIGHEMP_00252 PHI:2687 hfq 86.7 8e-37 1 90 0.9375 0.8824 rodents food poisoning regulators of systemic infection reduced virulence
FMIGHEMP_00256 PHI:2625 purA 85.2 3.7e-222 1 432 1.0000 1.0000 rodents food poisoning pathogenicity island reduced virulence
FMIGHEMP_00258 PHI:12252 nsrR 71.6 2.4e-53 1 141 0.9930 0.9456 monocots Stewart's wilt; leaf blight (maize) DNA-binding transcriptional regulator unaffected pathogenicity
FMIGHEMP_00285 PHI:10537 argR 84 9.9e-69 1 156 1.0000 1.0000 rodents infection arginine repressor reduced virulence
FMIGHEMP_00286 PHI:2959 mdh 76.6 1.1e-130 1 312 1.0000 1.0000 bony fishes enteric septicemia malate dehydrogenase reduced virulence
FMIGHEMP_00295 PHI:7130 greA 84.2 1.7e-71 1 158 1.0000 1.0000 rodents salmonellosis transcription elongation factor loss of pathogenicity
FMIGHEMP_00310 PHI:3878 pnp 83.1 0 1 709 1.0000 0.9944 even-toed ungulates food poisoning polynucleotide phosphorylase, an exoribonuclease involved in RNA processing and degradation reduced virulence
FMIGHEMP_00311 PHI:2459 nlpI 79.4 2.2e-130 1 295 1.0000 1.0000 eudicots fire blight tetratricopeptide lipoprotein reduced virulence
FMIGHEMP_00332 PHI:11411 yhbU 86.4 5.6e-170 1 331 1.0000 1.0000 rodents pneumonia ubiquinone biosynthesis protein unaffected pathogenicity
FMIGHEMP_00383 PHI:9326 metR 71.7 2e-124 1 297 0.9369 0.9519 eudicots fire blight HTH-type transcriptional regulator unaffected pathogenicity
FMIGHEMP_00384 PHI:9315 metE 75.4 0 1 754 0.9960 0.9934 eudicots fire blight 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase reduced virulence
FMIGHEMP_00396 PHI:10983 tatC 72.6 3e-102 1 259 0.9923 1.0000 rodents infection Sec-independent protein translocase protein reduced virulence
FMIGHEMP_00420 PHI:124167 narL 78.2 2.4e-89 9 219 0.9591 0.9769 rodents neonatal meningitis two-component system reduced virulence
FMIGHEMP_00422 PHI:123379 narK 78.1 5.3e-211 7 463 0.9870 0.9806 rodents salmonellosis nitrate/nitrite transporter reduced virulence
FMIGHEMP_00423 PHI:10512 narG 79.3 0 1 1241 0.9904 0.9936 rodents urinary tract infection respiratory nitrate reductase 1 alpha chain reduced virulence
FMIGHEMP_00424 PHI:10513 narH 84.8 2.4e-268 1 506 0.9787 0.9922 rodents urinary tract infection respiratory nitrate reductase 1 beta chain reduced virulence
FMIGHEMP_00426 PHI:10515 narI 77.3 6.4e-101 1 225 1.0000 1.0000 rodents urinary tract infection respiratory nitrate reductase 1 gamma chain reduced virulence
FMIGHEMP_00440 PHI:2960 frdA 87.1 0 1 598 1.0000 1.0000 bony fishes enteric septicemia fumarate reductase reduced virulence
FMIGHEMP_00476 PHI:10577 PccS1_001523 95.9 1.9e-46 1 98 1.0000 1.0000 monocots soft rot transcriptional regulator, Fis family, Fis unaffected pathogenicity
FMIGHEMP_00492 PHI:124123 tldD 83.4 1.8e-230 1 481 1.0000 1.0000 moths yersiniosis regulatory factor unaffected pathogenicity
FMIGHEMP_00500 PHI:3133 ptsN 70.5 5.4e-56 1 149 1.0000 0.9250 rodents gut-associated disease; diarrhea; enteritis; colitis part of the pyruvate-tricarboxylic acid cycle node reduced virulence
FMIGHEMP_00502 PHI:2906 rpoN 71.3 1.4e-193 1 491 1.0000 1.0000 eudicots fire blight sigma factor, regulating essential virulence gene expression loss of pathogenicity
FMIGHEMP_00520 PHI:8575 degQ (Dda3937_00697) 72 6.3e-180 4 459 0.9849 0.9978 eudicots soft rot protease reduced virulence
FMIGHEMP_00532 PHI:124164 ArcB 74.6 0 1 778 1.0000 1.0000 rodents neonatal meningitis two-component system reduced virulence
FMIGHEMP_00541 PHI:123444 ureF 99.5 2.8e-125 1 221 1.0000 0.9955 rodents catheter-associated urinary tract infection urease accessory protein UreF unaffected pathogenicity
FMIGHEMP_00554 PHI:11405 dedA 74.4 5.5e-89 1 215 0.9685 0.9773 rodents pneumonia DedA family inner membrane protein reduced virulence
FMIGHEMP_00573 PHI:6532 arcA 92 5.1e-125 1 238 1.0000 1.0000 birds meningitis aerobic respiration control protein reduced virulence
FMIGHEMP_00578 PHI:11408 yaaA 73.5 2.1e-103 1 257 0.9847 0.9291 rodents pneumonia alanine/glycine transport protein reduced virulence
FMIGHEMP_00585 PHI:3267 nhaR 76.8 1.4e-135 1 297 0.9738 0.9867 rodents infection transcriptional activator protein reduced virulence
FMIGHEMP_00593 PHI:8577 carA (Dda3937_01390) 84.9 7.9e-192 1 378 0.9767 0.9921 eudicots soft rot carbamoyl-phosphate synthase small subunit reduced virulence
FMIGHEMP_00602 PHI:10996 hybO 79.9 1.4e-177 5 368 0.9733 0.9758 rodents infection hydrogenase-2 small chain unaffected pathogenicity
FMIGHEMP_00603 PHI:10995 hybA 73.3 1.8e-152 1 337 1.0000 1.0000 rodents infection hydrogenase-2 operon protein unaffected pathogenicity
FMIGHEMP_00608 PHI:10076 STM14_RS15315 75.2 4.4e-102 155 388 0.6031 0.8069 eudicots infection hydrogenase assembly chaperone unaffected pathogenicity
FMIGHEMP_00613 PHI:7643 yedF 94.7 9.3e-39 5 80 0.9500 0.9870 primates salmonellosis hypothetical transcription factor reduced virulence
FMIGHEMP_00622 PHI:123534 phoB 79.5 2.6e-110 1 229 1.0000 1.0000 rodents gastroenteritis transcriptional regulator reduced virulence
FMIGHEMP_00639 PHI:11384 tsaA 79 1.1e-93 1 200 1.0000 1.0000 moths salmonellosis peroxiredoxin reduced virulence
FMIGHEMP_00679 PHI:3040 ClpP 85 9.3e-99 1 207 1.0000 1.0000 rodents food poisoning proteolytic component reduced virulence
FMIGHEMP_00680 PHI:9833 clpX 75.8 7.6e-180 5 423 0.9905 0.9836 eudicots black rot ATP-binding subunit of ATP-dependent Clp protease reduced virulence
FMIGHEMP_00681 PHI:7160 lon 89.2 0 1 784 1.0000 1.0000 eudicots fire blight protease increased virulence (hypervirulence)
FMIGHEMP_00682 PHI:8676 hupB (XAC1081) 71.1 1.5e-29 1 90 0.9890 1.0000 eudicots canker (Citrus) histone-like protein reduced virulence
FMIGHEMP_00694 PHI:3819 ymoA 88.1 1.9e-29 1 67 1.0000 1.0000 rodents pneumonic plague represses the transcription and expression of T3SS genes at room temperature increased virulence (hypervirulence)
FMIGHEMP_00696 PHI:7307 AcrB 76.5 0 1 1044 0.9924 0.9933 rodents salmonellosis efflux pump membrane transporter reduced virulence
FMIGHEMP_00707 PHI:7575 yjiY 89.3 0 1 716 1.0000 1.0000 rodents salmonellosis peptide-utilizing carbon starvation protein reduced virulence
FMIGHEMP_00761 PHI:6508 DksA 94.7 7.8e-79 1 151 1.0000 1.0000 rodents salmonellosis response regulator reduced virulence
FMIGHEMP_00771 PHI:123919 relA 78.1 0 1 743 0.9960 0.9946 nematodes neonatal meningitis GTP pyrophosphokinase reduced virulence
FMIGHEMP_00783 PHI:11344 c2516 70.9 1.3e-127 19 358 0.9444 0.9659 birds avian colibacillosis putative iron transport protein reduced virulence
FMIGHEMP_00851 PHI:9154 potE 82.3 3e-203 1 434 0.9819 0.9909 birds colibacillosis None unaffected pathogenicity
FMIGHEMP_00891 PHI:8581 lysA (Dda3937_02577) 72.1 8.2e-171 10 411 0.9710 0.9571 eudicots soft rot diamiopimelate decarboxylase reduced virulence
FMIGHEMP_00899 PHI:8942 nqrD (PA2996) 70.5 9.2e-78 1 207 0.9904 0.9241 moths nosocomial infection Na(+)-translocating NADH-quinone reductase unaffected pathogenicity
FMIGHEMP_00918 PHI:10380 RecA 72.2 5.6e-136 3 329 0.9211 0.9370 nematodes nosocomial infection DNA strand exchange and recombination protein reduced virulence
FMIGHEMP_00920 PHI:7161 csrA 96.6 4.6e-25 1 59 0.9516 0.9672 eudicots fire blight RNA-binding protein reduced virulence
FMIGHEMP_00928 PHI:3731 LuxS 84.2 1.3e-82 1 171 1.0000 1.0000 birds colibacillosis; cellulitis; swollen head syndrome controller in the quorum sensing reduced virulence
FMIGHEMP_00946 PHI:10595 clpB 81.3 0 1 857 0.9988 1.0000 eudicots soft rot chaperone protein unaffected pathogenicity
FMIGHEMP_00968 PHI:8968 proV 72.9 2.4e-167 1 398 0.9975 0.9950 rodents pneumonia glycine betaine/L-proline transport ATP-binding protein reduced virulence
FMIGHEMP_00974 PHI:7263 cspE 85.5 1.1e-30 1 69 1.0000 1.0000 primates salmonellosis cold shock protein reduced virulence
FMIGHEMP_00994 PHI:124243 gltI 75.5 2.9e-125 1 297 1.0000 1.0000 rodents neonatal meningitis glutamate transporters reduced virulence
FMIGHEMP_01002 PHI:7671 ybeY 78.7 2e-69 1 155 1.0000 0.9873 primates yersiniosis endoribonuclease reduced virulence
FMIGHEMP_01101 PHI:11509 fur 86.4 8.8e-75 1 147 0.9932 0.9800 rodents salmonellosis ferric uptake regulation protein reduced virulence
FMIGHEMP_01122 PHI:7962 sdhC 74.7 4.7e-34 3 93 0.9785 0.7054 nematodes urinary tract infection succinate dehydrogenase reduced virulence
FMIGHEMP_01123 PHI:7963 sdhD 70.4 3.5e-39 1 114 1.0000 1.0000 nematodes urinary tract infection succinate dehydrogenase reduced virulence
FMIGHEMP_01124 PHI:7964 sdhA 92 0 1 588 1.0000 1.0000 nematodes urinary tract infection succinate dehydrogenase flavoprotein subunit reduced virulence
FMIGHEMP_01125 PHI:7965 sdhB 87.8 4.2e-127 1 238 1.0000 1.0000 nematodes urinary tract infection succinate dehydrogenase iron-sulfur subunit reduced virulence
FMIGHEMP_01141 PHI:10905 tolB 74.7 2.5e-194 1 431 1.0000 1.0000 rodents colitis colicin import protein reduced virulence
FMIGHEMP_01172 PHI:10987 moaA 73.6 3.2e-146 3 326 0.9939 0.9909 rodents infection GTP 3',8-cyclase unaffected pathogenicity
FMIGHEMP_01211 PHI:2652 magA 82.4 1e-91 1 193 1.0000 1.0000 rodents urinary tract infection; nosocomial pneumonia; abdominal infection contributes to K1 capsular polysaccharide (CPS) biosynthesis reduced virulence
FMIGHEMP_01222 PHI:9324 hisA 71.3 5e-99 1 244 0.9959 0.9959 eudicots fire blight N-(5'-phospho-L-ribosyl-formimino)-5-amino-1-(5'-phosphoribosyl)-4-imidazolecarboxamide isomerase unaffected pathogenicity
FMIGHEMP_01227 PHI:5109 prt 86.6 1.4e-143 1 299 1.0000 1.0000 rodents colitis OAg biosynthesis reduced virulence
FMIGHEMP_01243 PHI:10536 artP 79.8 1.1e-106 8 249 0.9719 1.0000 rodents infection arginine ABC transporter, ATP-binding protein reduced virulence
FMIGHEMP_01251 PHI:8569 clpA (Dda3937_02363) 81.1 0 1 755 0.9882 0.9894 eudicots soft rot ATP-dependent Clp protease ATP-binding subunit reduced virulence
FMIGHEMP_01257 PHI:6497 lrp 98.8 2.6e-88 1 164 1.0000 1.0000 moths None global transcription factor reduced virulence
FMIGHEMP_01260 PHI:6447 rarA 85.5 1.9e-221 9 455 0.9781 1.0000 nematodes pneumonia Holliday junction DNA helicase reduced virulence
FMIGHEMP_01273 PHI:7061 aroA 76.7 5.3e-189 1 424 0.9907 0.9930 rodents salmonellosis 3-phosphoshikimate 1-carboxyvinyltransferase unaffected pathogenicity
FMIGHEMP_01276 PHI:124345 ihfB 87.4 6.7e-44 1 95 1.0000 1.0000 primates pneumonia integration host factor reduced virulence
FMIGHEMP_01308 PHI:12051 evpB 74.4 4.2e-222 13 492 0.9756 0.9695 eukaryotes colibacillosis type VI secretion system protein unaffected pathogenicity
FMIGHEMP_01310 PHI:123750 Hcp 89.5 2.4e-92 1 172 1.0000 1.0000 bony fishes furunculosis effector protein effector (plant avirulence determinant)
FMIGHEMP_01348 PHI:3676 rmf3 80.4 4.4e-19 1 51 0.9107 0.9273 eudicots fire blight None unaffected pathogenicity
FMIGHEMP_01352 PHI:4160 OmpA2 70.8 4.1e-142 1 360 0.9945 0.9943 moths pneumonia outer membrane proteins reduced virulence
FMIGHEMP_01375 PHI:7263 cspE 75 2.2e-23 7 70 0.9143 1.0000 primates salmonellosis cold shock protein reduced virulence
FMIGHEMP_01450 PHI:8898 cobB (Yp_1760) 72 1.3e-111 4 271 0.9404 0.9568 rodents plague protein deacetylase reduced virulence
FMIGHEMP_01455 PHI:7904 phoP 70.7 2.4e-92 1 222 0.9911 0.9955 even-toed ungulates zoonotic infection response regulator protein unaffected pathogenicity
FMIGHEMP_01473 PHI:7263 cspE 75 2.2e-23 7 70 0.9143 1.0000 primates salmonellosis cold shock protein reduced virulence
FMIGHEMP_01565 PHI:7263 cspE 70.6 1.3e-23 3 70 0.9714 1.0000 primates salmonellosis cold shock protein reduced virulence
FMIGHEMP_01606 PHI:124002 yebE 81.9 3.2e-129 1 292 1.0000 1.0000 rodents colitis cpx-regulated gene unaffected pathogenicity
FMIGHEMP_01629 PHI:124344 ihfA 89.8 7.4e-46 1 98 1.0000 0.9899 primates pneumonia integration host factor reduced virulence
FMIGHEMP_01633 PHI:7950 arnC 73.9 4.4e-135 1 326 1.0000 0.9908 moths pneumonia putative sugar transferase unaffected pathogenicity
FMIGHEMP_01634 PHI:7951 arnA 72.7 1.9e-299 1 651 0.9864 0.9849 moths pneumonia hypothetical protein unaffected pathogenicity
FMIGHEMP_01700 PHI:123750 Hcp 89.5 2.4e-92 1 172 1.0000 1.0000 bony fishes furunculosis effector protein effector (plant avirulence determinant)
FMIGHEMP_01712 PHI:5013 znuB 76.9 3.9e-102 1 260 0.9962 0.9962 rodents gut-associated disease; diarrhea; enteritis; colitis zinc transporter reduced virulence
FMIGHEMP_01713 PHI:11909 znuC 74.5 5.2e-101 1 239 0.9917 0.9447 rodents pneumonic plague zinc transporter reduced virulence
FMIGHEMP_01727 PHI:4108 fadD 71.1 1.6e-238 1 552 0.9822 0.9806 rabbits and hares cholera encoding a long-chain fatty acyl coenzyme A (acyl-CoA) ligase reduced virulence
FMIGHEMP_01763 PHI:4876 FNR 93.9 1.9e-130 1 244 0.9683 0.9760 rodents infection global regulator reduced virulence
FMIGHEMP_01773 PHI:11383 ahpC 87.7 4.9e-99 1 187 1.0000 1.0000 moths salmonellosis peroxiredoxin reduced virulence
FMIGHEMP_01800 PHI:11664 dmsA 75.3 0 14 811 0.9803 0.9963 rodents Haemophilus influenzae disease putative dimethylsulfoxide (DMSO) reductase, catalytic subunit reduced virulence
FMIGHEMP_01870 PHI:10048 fumC 83.6 1.1e-227 1 463 0.9957 0.9914 rodents salmonellosis fumarate hydratase class II reduced virulence
FMIGHEMP_01916 PHI:9321 trpB 83.6 2.8e-200 1 396 1.0000 1.0000 eudicots fire blight tryptophan synthase beta chain reduced virulence
FMIGHEMP_01960 PHI:6114 RovA 77.9 6.3e-54 1 140 0.9859 0.9790 rodents plague MarR-family regulator reduced virulence
FMIGHEMP_01967 PHI:11377 sodB 80.2 2.3e-91 1 192 1.0000 0.9948 moths salmonellosis cytoplasmic superoxide dismutase increased virulence (hypervirulence)
FMIGHEMP_01976 PHI:10107 STM14_RS07745 (pykF) 84.5 6.8e-222 1 470 1.0000 1.0000 eudicots infection pyruvate kinase I reduced virulence
FMIGHEMP_01985 PHI:10100 STM14_RS07710 (sufC) 81.9 9.1e-117 1 248 1.0000 1.0000 eudicots infection Fe-S cluster assembly ATPase reduced virulence
FMIGHEMP_01986 PHI:6893 sufB 80.6 2.2e-234 5 498 0.9920 0.9939 rodents salmonellosis sulfur mobilization unaffected pathogenicity
FMIGHEMP_02029 PHI:7520 VK055_1952 75.9 3.9e-212 8 491 0.9857 0.9918 rodents pneumonia betaine aldehyde dehydrogenase unaffected pathogenicity
FMIGHEMP_02057 PHI:6097 hns 80 3.2e-52 1 134 1.0000 1.0000 rodents pneumonia pleiotropic regulator increased virulence (hypervirulence)
FMIGHEMP_02059 PHI:124019 GalU 76.1 3.3e-129 1 297 0.9867 0.9801 birds salmonellosis uridine diphosphate–glucose pyrophosphorylase reduced virulence
FMIGHEMP_02080 PHI:11407 gntR 77.8 1e-104 1 234 0.9791 0.9791 rodents pneumonia fatty acid metabolism regulator reduced virulence
FMIGHEMP_02114 PHI:124107 ModA (CP110673) 98.8 2.1e-137 1 251 1.0000 1.0000 rodents urinary tract infection the molybdate-binding protein reduced virulence
FMIGHEMP_02162 PHI:8579 guaB (Dda3937_00004) 89.1 5.6e-243 1 487 0.9980 1.0000 eudicots soft rot IMP dehydrogenase reduced virulence
FMIGHEMP_02196 PHI:5063 ppk 100 0 1 693 1.0000 1.0000 rodents urinary tract infection polyphosphate kinase reduced virulence
FMIGHEMP_02204 PHI:9198 yegN 75.9 0 6 1028 0.9808 0.9952 rodents urinary tract infection multidrug efflux system subunit reduced virulence
FMIGHEMP_02215 PHI:8505 BfvR (YPO1737) 80.2 1.1e-54 1 121 0.9453 0.9453 rodents pneumonic plague AraC-family transcriptional regulator increased virulence (hypervirulence)
FMIGHEMP_02236 PHI:3922 FliZ 85.1 1.7e-80 1 168 0.9545 0.9882 moths None global regulatory protein reduced virulence
FMIGHEMP_02249 PHI:123276 fliF 100 0 1 573 1.0000 1.0000 primates urinary tract infection; urolithiasis flagellar M-ring protein reduced virulence
FMIGHEMP_02278 PHI:8731 flhA 76.2 3.9e-298 1 694 0.9971 1.0000 rodents typhoid flagellar biosynthesis protein reduced virulence
FMIGHEMP_02280 PHI:10050 cheZ 70.3 7.6e-75 17 218 0.9266 0.9299 rodents salmonellosis protein phosphatase/ chemotactic response protein reduced virulence
FMIGHEMP_02281 PHI:8732 cheY 82.2 6.1e-56 1 129 1.0000 1.0000 rodents typhoid chemotaxis regulator protein reduced virulence
FMIGHEMP_02282 PHI:6461 cheB 76.6 2.6e-149 1 350 1.0000 1.0000 rodents salmonellosis chemotaxis reduced virulence
FMIGHEMP_02286 PHI:6536 cheW 82.5 1.6e-64 8 161 0.9277 0.9222 birds meningitis chemotaxis protein unaffected pathogenicity
FMIGHEMP_02290 PHI:8572 flhC (Dda3937_02784) 82.3 2.1e-84 1 186 0.9637 0.9635 eudicots soft rot flagellar transcriptional activator reduced virulence
FMIGHEMP_02291 PHI:12271 FlhD 80.2 3.9e-46 1 116 1.0000 0.9748 flies opportunistic infection flagellar transcriptional regulator FlhD unaffected pathogenicity
FMIGHEMP_02295 PHI:7262 cspC 89.6 8.2e-31 4 70 0.9571 0.9710 primates salmonellosis cold shock protein reduced virulence
FMIGHEMP_02306 PHI:10115 STM14_RS07780 (ttrB) 80.3 1.3e-120 1 244 0.9919 0.9760 eudicots infection tetrathionate reductase subunit B reduced virulence
FMIGHEMP_02356 PHI:10469 RcsB (YE1397) 92 5.7e-107 1 213 0.9771 0.9907 primates yersiniosis; acute gastroenteritis transcriptional regulatory protein increased virulence (hypervirulence)
FMIGHEMP_02367 PHI:10648 katA 77.3 2e-232 2 475 0.9793 0.9855 rodents opportunistic infection catalase unaffected pathogenicity
FMIGHEMP_02381 PHI:8937 nuoI (PA2644) 81.1 2.1e-83 6 180 0.9722 0.9615 moths nosocomial infection NADH-quinone oxidoreductase unaffected pathogenicity
FMIGHEMP_02396 PHI:9843 ackA 72.1 1e-165 3 399 0.9925 0.9925 flies infection acetate kinase unaffected pathogenicity
FMIGHEMP_02397 PHI:123168 pta 83.5 0 1 712 0.9972 1.0000 rodents salmonellosis phosphate acetyltransferase reduced virulence
FMIGHEMP_02416 PHI:9317 purF 82.2 7.7e-248 1 505 1.0000 1.0000 eudicots fire blight amidophosphoribosyltransferase reduced virulence
FMIGHEMP_02471 PHI:9311 ptsH 87.1 3.9e-35 1 85 1.0000 1.0000 eudicots fire blight phosphocarrier protein HPr reduced virulence
FMIGHEMP_02472 PHI:9312 ptsI 77.7 4.4e-255 1 575 1.0000 1.0000 eudicots fire blight phosphoenolpyruvate-protein phosphotransferase reduced virulence
FMIGHEMP_02502 PHI:6892 iscU 89.8 3.9e-63 1 128 1.0000 1.0000 rodents salmonellosis Fe-S cluster sensor reduced virulence
FMIGHEMP_02504 PHI:3043 IscR 80.5 2.1e-69 1 163 0.9939 0.9939 rodents gastrointestinal disease; yersiniosis type III secretion system reduced virulence
FMIGHEMP_02510 PHI:2962 glyA 86.8 1.1e-215 1 417 1.0000 1.0000 bony fishes enteric septicemia serine hydroxymethyltransferase reduced virulence
FMIGHEMP_02511 PHI:123275 hmpA 99.5 1e-231 1 396 1.0000 1.0000 primates urinary tract infection; urolithiasis flavohemoprotein loss of pathogenicity
FMIGHEMP_02518 PHI:8580 purL (Dda3937_03379) 75.7 0 1 1294 0.9985 0.9977 eudicots soft rot phosphoribosylformyl-glycineamide synthetase reduced virulence
FMIGHEMP_02531 PHI:3724 RNase III 85.4 7.5e-110 1 226 1.0000 1.0000 moths food poisoning endoribonucleases reduced virulence
FMIGHEMP_02537 PHI:5238 RpoE 100 5.2e-104 1 192 1.0000 1.0000 rodents urinary tract infection RNA polymerase sigma-E factor reduced virulence
FMIGHEMP_02548 PHI:4218 smpB 85 1.8e-78 1 160 1.0000 1.0000 birds avian colibacillosis trans-translation is a bacterial translational control system that directs the modification and degradation of proteins, reduced virulence
FMIGHEMP_02675 PHI:2961 gcvP 70.9 0 1 957 0.9990 0.9990 bony fishes enteric septicemia glycine dehydrogenase reduced virulence
FMIGHEMP_02703 PHI:3135 pdhR 81.5 3.1e-115 6 259 0.9732 1.0000 rodents gut-associated disease; diarrhea; enteritis; colitis part of the pyruvate-tricarboxylic acid cycle node reduced virulence
FMIGHEMP_02735 PHI:2672 fruR 83.2 1.1e-162 1 334 0.9970 1.0000 rodents food poisoning regulators of systemic infection reduced virulence
FMIGHEMP_02738 PHI:8578 leuA (Dda3937_04301) 74 8e-224 1 519 1.0000 1.0000 eudicots soft rot 2-isopropylmalate synthase reduced virulence
FMIGHEMP_02739 PHI:8963 leuB 78.7 7.4e-168 1 362 0.9972 0.9972 rodents pneumonia 3-isopropylmalate dehydrogenase reduced virulence
FMIGHEMP_02740 PHI:8964 leuC 84.2 4.8e-228 1 463 0.9872 0.9936 rodents pneumonia 3-isopropylmalate dehydratase large subunit reduced virulence
FMIGHEMP_02741 PHI:8965 leuD 78.2 2.5e-88 3 199 0.9850 0.9801 rodents pneumonia 3-isopropylmalate dehydratase small subunit reduced virulence
FMIGHEMP_02747 PHI:9150 speB 81.8 3.1e-151 5 306 0.9869 0.9869 birds colibacillosis agmatinase reduced virulence
FMIGHEMP_02763 PHI:10593 hcp 82.4 3.5e-278 1 550 1.0000 1.0000 eudicots soft rot hydroxylamine reductase unaffected pathogenicity
FMIGHEMP_02783 PHI:10587 kduD 70.5 1.7e-99 1 251 1.0000 0.9921 monocots soft rot 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase unaffected pathogenicity
FMIGHEMP_02813 PHI:11418 ppiB 83.5 2.9e-79 1 164 1.0000 1.0000 rodents salmonellosis peptidyl-prolyl cis-trans isomerase reduced virulence
FMIGHEMP_02837 PHI:6472 htpG 81.4 4.5e-298 3 623 0.9904 0.9968 rodents diarrhea heat shock protein 90 chaperone reduced virulence
FMIGHEMP_02875 PHI:10243 pmpA 100 3.8e-96 1 183 1.0000 1.0000 rodents urinary tract infection; urolithiasis F7-2 fimbrial protein reduced virulence
FMIGHEMP_02889 PHI:10574 rpoS 80.5 9.5e-146 1 327 0.9939 0.9970 monocots soft rot RNA polymerase sigma factor unaffected pathogenicity
FMIGHEMP_02902 PHI:9323 cysI3 75.4 1.5e-263 8 571 0.9792 0.9860 eudicots fire blight sulfite reductase unaffected pathogenicity
FMIGHEMP_02944 PHI:9334 map 77 3.5e-122 1 265 1.0000 0.9962 rodents colitis effector protein effector (plant avirulence determinant)
FMIGHEMP_02967 PHI:9372 amiC 72 7.8e-169 1 414 0.9857 0.9928 rodents bubonic plague N-acetylmuramoyl-L-alanine amidase unaffected pathogenicity
FMIGHEMP_02994 PHI:10573 rsmA 75.7 2.1e-119 1 272 1.0000 1.0000 monocots soft rot ribosomal RNA small subunit methyltransferase A unaffected pathogenicity
FMIGHEMP_03012 PHI:6697 yqiC 70.9 1.4e-26 1 86 0.8269 0.8586 primates salmonellosis membrane fusogenic activity reduced virulence
FMIGHEMP_03121 PHI:9804 int 100 3.8e-14 1 37 0.1160 1.0000 rodents gastroenteritis integrase reduced virulence
FMIGHEMP_03242 PHI:123442 yntA 99.8 0 1 527 1.0000 1.0000 rodents catheter-associated urinary tract infection putative nickel/di-oligopepetide ABC transporter, substrate-binding protein reduced virulence
FMIGHEMP_03248 PHI:10070 STM14_RS15285 75.8 6.7e-264 14 577 0.9775 0.9930 eudicots infection formate hydrogenlyase subunit 4 unaffected pathogenicity
FMIGHEMP_03256 PHI:6420 EF-P 84.6 1.5e-92 1 188 1.0000 1.0000 rodents salmonellosis elongation factor increased virulence (hypervirulence)
FMIGHEMP_03274 PHI:123643 dcuA 82.8 2.9e-190 1 441 1.0000 1.0000 rodents neonatal meningitis regulatory protein unaffected pathogenicity
FMIGHEMP_03401 PHI:9310 pgi 79 2.2e-264 1 548 1.0000 1.0000 eudicots fire blight glucose-6-phosphate isomerase reduced virulence
FMIGHEMP_03408 PHI:11150 edd 72.9 2e-261 16 616 0.9725 0.9804 eudicots soft rot (potato); blackleg disease (potato) phosphogluconate dehydratase unaffected pathogenicity
FMIGHEMP_03409 PHI:11149 eda 79.7 2.9e-95 1 212 0.9953 0.9953 eudicots soft rot (potato); blackleg disease (potato) 2-keto-3-deoxy-6-phosphogluconate aldolase reduced virulence
FMIGHEMP_03413 PHI:9313 metA 73.8 1.1e-135 1 309 1.0000 1.0000 eudicots fire blight homoserine O-succinyltransferase reduced virulence
FMIGHEMP_03424 PHI:3074 hupA 74.4 5.6e-32 1 90 1.0000 1.0000 bony fishes hemorrhagic septicemia nucleoid-associated protein, is a basic DNA-binding protein involved in gene regulation reduced virulence
FMIGHEMP_03438 PHI:7860 RpoB 70.7 0 1 1338 0.9970 1.0000 nematodes nosocomial infection beta-subunit of the RNA polymerase reduced virulence
FMIGHEMP_03445 PHI:10282 tufA 75.8 6e-179 1 393 0.9975 0.9975 primates skin infection; food poisoning; respiratory disease elongation factor Tu increased virulence (hypervirulence)
FMIGHEMP_03473 PHI:4063 Crp 98.6 7.7e-117 1 210 1.0000 1.0000 rodents pneumonic plague transcriptional regulator reduced virulence
FMIGHEMP_03518 PHI:10548 spoT 84.5 0 1 708 1.0000 1.0000 rodents salmonellosis (P)ppGpp synthetase reduced virulence
FMIGHEMP_03521 PHI:123647 gltS 78.2 6.8e-170 1 399 0.9876 0.9950 rodents neonatal meningitis regulatory protein unaffected pathogenicity
FMIGHEMP_03531 PHI:11030 bipA 86.4 6.1e-308 1 602 0.9950 0.9918 rodents pneumonic plague putative GTPase reduced virulence
FMIGHEMP_03532 PHI:7742 glnA 82.7 3.7e-236 1 468 0.9979 0.9979 primates salmonellosis glutamine synthetase reduced virulence
FMIGHEMP_03541 PHI:11693 ompR 87.8 4.1e-122 1 237 0.9875 0.9916 primates infection transcriptional regulator reduced virulence
FMIGHEMP_03547 PHI:123166 phoU 81.1 1.3e-110 1 238 0.9754 0.9876 rodents salmonellosis phosphate-specific transport system accessory protein PhoU reduced virulence
FMIGHEMP_03565 PHI:10919 EaAdeP (EAMY 3685) 78.7 4.7e-188 13 444 0.9558 0.9908 eudicots fire blight putative AzgA family transporter reduced virulence
FMIGHEMP_03580 PHI:3272 glpD 79 1.1e-238 1 496 0.9980 0.9286 rodents pneumonic plague glycerol-3-phosphate dehydrogenase involved in glycerol fermentation unaffected pathogenicity
FMIGHEMP_03582 PHI:9325 metF 80.5 1.2e-144 1 297 0.9933 0.9867 eudicots fire blight methylenetetrahydrofolate reductase unaffected pathogenicity
FMIGHEMP_03597 PHI:123443 nikA 99.2 3.8e-306 1 525 1.0000 1.0000 rodents catheter-associated urinary tract infection ABC transporter. substrate-binding protein reduced virulence
FMIGHEMP_03623 PHI:123868 DHDPS (LC602498) 81.8 6.3e-141 1 296 0.9966 1.0000 bony fishes gastroenteritis dihydrodipicolinate synthase unaffected pathogenicity
FMIGHEMP_03624 PHI:11065 STM14_1285 (AsiR) 73.2 2.9e-114 3 292 0.9831 0.9932 rodents salmonellosis putative RpiR-family transcriptional regulator increased virulence (hypervirulence)
FMIGHEMP_03638 PHI:123750 Hcp 88.4 1.6e-91 1 172 1.0000 1.0000 bony fishes furunculosis effector protein effector (plant avirulence determinant)
FMIGHEMP_03683 PHI:11376 sodA 77.2 3.1e-94 1 206 0.9952 0.9951 moths salmonellosis cytoplasmic superoxide dismutase reduced virulence
FMIGHEMP_03684 PHI:9227 acs 78.2 0 1 650 0.9969 0.9969 birds avian colisepticemia acetyl-coenzyme A synthetase reduced virulence
FMIGHEMP_03686 PHI:9229 actP 80.3 3.4e-233 20 551 0.9655 0.9672 birds avian colisepticemia acetate/glycolate:cation symporter reduced virulence
FMIGHEMP_03706 PHI:9436 atpB 80.1 1.5e-120 4 274 0.9891 0.9963 rodents gastroenteritis F0F1 ATP synthase subunit A reduced virulence
FMIGHEMP_03715 PHI:9308 glmS 79.5 4.7e-276 1 608 1.0000 1.0000 eudicots fire blight glucosamine-fructose-6-phosphateaminotransferase reduced virulence
FMIGHEMP_03765 PHI:10994 fdoG 83.5 0 1 803 1.0000 1.0000 rodents infection formate dehydrogenase-O major subunit unaffected pathogenicity
FMIGHEMP_03766 PHI:10994 fdoG 87.7 1e-99 1 195 1.0000 1.0000 rodents infection formate dehydrogenase-O major subunit unaffected pathogenicity






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
FMIGHEMP_00022 QIF46724.1|GT4 99.7 5.42e-274 1 375 1 1
FMIGHEMP_00023 AGS61613.1|GT9 99.7 3.24e-247 1 333 1 1
FMIGHEMP_00024 QWV41993.1|GT4 100 4.45e-274 1 368 1 1
FMIGHEMP_00025 QLJ19317.1|GT4 100 2.08e-282 1 392 1 1
FMIGHEMP_00029 QFV07232.1|GT2 99.6 4.02e-188 1 259 1 1
FMIGHEMP_00030 QEG43988.1|GT30 100 1.01e-308 1 425 1 1
FMIGHEMP_00031 VEB80960.1|GT4 100 1.8e-268 1 367 1 1
FMIGHEMP_00032 QTO08800.1|GT4 100 1.84e-282 1 377 1 1
FMIGHEMP_00033 QEG43991.1|GT9 99.2 4.37e-263 1 355 1 1
FMIGHEMP_00035 AUT93398.1|GT9 99.4 2.16e-260 1 358 1 1
FMIGHEMP_00036 QFV07238.1|GT9 99.1 6.96e-235 1 319 1 1
FMIGHEMP_00037 AUU40915.1|GT9 100 1.29e-257 1 350 1 1
FMIGHEMP_00049 QIM26836.1|GT2 100 1.77e-231 1 325 1 1
FMIGHEMP_00053 AXY99477.1|GT4 100 7.67e-271 1 378 1 1
FMIGHEMP_00062 QUY06271.1|GT8 98.7 5.06e-229 1 312 1 1
FMIGHEMP_00063 QSI20671.1|GT32 99.6 9.57e-198 1 263 1 1
FMIGHEMP_00064 QEG44028.1|GT8 99.1 3.06e-232 1 316 1 1
FMIGHEMP_00065 QSI20669.1|GT2 97.6 3.6e-238 1 330 1 1
FMIGHEMP_00066 QSI20668.1|GT4 98.9 3.88e-261 1 354 1 1
FMIGHEMP_00094 QLJ19426.1|GT2 99.7 7.37e-250 1 327 1 1
FMIGHEMP_00199 QLK59446.1|GT0 76.5 1.2e-211 1 375 0.9973 0.9973
FMIGHEMP_00206 QLJ19520.1|GT56 100 6.79e-270 1 361 1 1
FMIGHEMP_00208 QIM23454.1|GT26 100 9.5e-180 1 245 1 1
FMIGHEMP_00534 QLJ19824.1|GT51 100 1.1e-163 1 233 1 1
FMIGHEMP_00567 QYH21099.1|GH23 100 0 1 639 1 1
FMIGHEMP_00717 AWK40744.1|CE9 71.2 5.34e-210 1 403 1 1
FMIGHEMP_00764 QKQ94822.1|GT51 100 0 1 770 1 1
FMIGHEMP_00777 QGM64353.1|CBM50|GH23 100 0 1 444 1 1
FMIGHEMP_00828 QKQ94884.1|GT83 100 0 1 548 1 1
FMIGHEMP_00840 ALE24649.1|GH65 100 0 1 905 1 1
FMIGHEMP_00868 QOV83728.1|GH23 100 7.51e-260 1 356 1 1
FMIGHEMP_00990 AMJ20771.1|GH13_26 79.2 0 1 860 1 1
FMIGHEMP_00994 UWT99371.1|GT4 95.6 4.34e-202 1 297 1 1
FMIGHEMP_01017 QPI90310.1|CE9 100 5.12e-285 1 387 1 1
FMIGHEMP_01052 AUU39890.1|GH24 100 4.51e-107 1 156 1 1
FMIGHEMP_01125 UXA35285.1|GT51 97.1 2.07e-175 1 238 1 1
FMIGHEMP_01442 ARX07955.1|GH3 100 3.35e-243 1 339 1 1
FMIGHEMP_01480 QHP76186.1|GH24 100 1.57e-107 1 156 1 1
FMIGHEMP_01524 QTO10122.1|GH24 100 1.4e-110 1 156 1 1
FMIGHEMP_01617 ARX35106.1|GH23 100 2.82e-166 1 233 1 1
FMIGHEMP_01633 QHZ88976.1|GT2 100 4.13e-226 1 326 1 1
FMIGHEMP_01636 ATC76084.1|GT83 100 0 1 553 1 1
FMIGHEMP_01715 QLJ20970.1|CBM50 100 9.07000001236494e-316 1 442 1 1
FMIGHEMP_01733 ATC75996.1|GH103 100 1.81e-272 1 375 1 1
FMIGHEMP_02232 QXF33454.1|GH13_3 81.5 2.5e-260 18 465 0.9532 0.9573
FMIGHEMP_02265 QOR41390.1|GH73 100 8.7e-229 1 328 1 1
FMIGHEMP_02493 QOV81774.1|GT51 100 0 1 773 1 1
FMIGHEMP_02519 QKQ96451.1|GH23 100 0 1 489 1 1
FMIGHEMP_02719 AGS60604.1|CE11 99.7 7.69e-221 1 306 1 1
FMIGHEMP_02725 AUU13575.1|GT28 100 5.94e-259 1 360 1 1
FMIGHEMP_02753 ATC79703.1|GT2 100 0 1 865 1 1
FMIGHEMP_02780 QTO07778.1|PL8_2 100 0 1 1021 1 1
FMIGHEMP_02781 QTO07779.1|PL8_2 100 0 1 1013 1 1
FMIGHEMP_02782 QKQ96649.1|GH105 100 4.63e-279 1 356 1 1
FMIGHEMP_02785 QSC09607.1|CE9 100 5.99e-285 1 389 1 1
FMIGHEMP_02795 QLJ18232.1|GH154 100 0 1 491 1 1
FMIGHEMP_02841 QTO07835.1|GH32 100 0 1 488 1 1
FMIGHEMP_02890 QPI96929.1|CBM50 100 1.52e-243 1 374 1 1
FMIGHEMP_02930 QXL78627.1|GT19 100 6.93e-279 1 388 1 1
FMIGHEMP_02963 QSC09765.1|GH102 100 6.77e-267 1 364 1 1
FMIGHEMP_03092 AGP81155.1|GH23 100 4.15e-127 1 182 1 1
FMIGHEMP_03243 QER00685.1|GT2 100 5.39e-249 1 330 1 1
FMIGHEMP_03307 QIM26240.1|AA10 100 4.77e-150 1 203 1 1
FMIGHEMP_03312 AND11729.1|GH73 100 1.7e-187 1 264 1 1
FMIGHEMP_03588 QSC10276.1|GH33 99.7 5.16e-273 1 350 1 1
FMIGHEMP_03602 QIM30040.1|GH4 100 0 1 450 1 1
FMIGHEMP_03670 QQZ27007.1|GT51 99.9 0 1 820 1 0.9716
FMIGHEMP_03752 AWF42831.1|GT2 100 0 1 704 1 1
FMIGHEMP_03758 QIG03487.1|GH8 99.7 5.07e-260 1 342 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
FMIGHEMP_00070 3.A.1.6.1 77.1 2.5e-149 2 333 0.9940 1.1877 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
FMIGHEMP_00077 1.A.8.1.1 70.9 8.2e-111 1 268 0.9889 0.9502 1 Channels/Pores 1.A α-Type Channels 1.A.8 The Major Intrinsic Protein (MIP) Family
FMIGHEMP_00096 2.A.1.6.4 77.5 1.8e-225 3 500 0.9960 0.9960 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.1 The Major Facilitator Superfamily (MFS)
FMIGHEMP_00152 3.A.5.1.1 94.1 4e-232 1 440 1.0000 2.1359 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.5 The General Secretory Pathway (Sec) Family
FMIGHEMP_00160 1.A.22.1.1 78.2 7.3e-52 1 133 0.9852 0.9706 1 Channels/Pores 1.A α-Type Channels 1.A.22 The Large Conductance Mechanosensitive Ion Channel (MscL) Family
FMIGHEMP_00161 2.A.38.1.1 83.4 1.1e-219 1 458 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.38 The K+ Transporter (Trk) Family
FMIGHEMP_00197 9.B.146.1.7 77.3 1.2e-154 1 352 0.9832 0.9591 9 Incompletely Characterized Transport Systems 9.B Putative transport proteins 9.B.146 The Putative Undecaprenyl-phosphate N-Acetylglucosaminyl Transferase (MurG) Family
FMIGHEMP_00201 9.B.18.2.4 83 4.6e-178 1 353 0.9944 0.9944 9 Incompletely Characterized Transport Systems 9.B Putative transport proteins 9.B.18 The Xanthan Glycosyl Transferase, GumD (GumD) Family
FMIGHEMP_00205 2.A.66.2.3 72.4 1.2e-164 1 417 0.9976 0.9976 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.66 The Multidrug/Oligosaccharidyl-lipid/Polysaccharide (MOP) Flippase Superfamily
FMIGHEMP_00207 9.B.128.1.1 75.8 7.9e-191 1 446 0.9824 0.9933 9 Incompletely Characterized Transport Systems 9.B Putative transport proteins 9.B.128 The O-antigen Polymerase, WzyE (WzyE) Family
FMIGHEMP_00252 9.B.468.1.1 85.6 1.8e-36 1 90 0.9375 0.8824 9 Incompletely Characterized Transport Systems 9.B Putative transport proteins 9.B.468 The Hfq RNA Chaparone Protein (Hfq) Family
FMIGHEMP_00274 1.A.112.2.12 74.9 3.4e-186 1 431 0.9431 0.9685 1 Channels/Pores 1.A α-Type Channels 1.A.112 The Cyclin M Mg2+ Exporter (CNNM) Family
FMIGHEMP_00298 3.A.29.1.5 86.7 0 4 633 0.9707 0.9814 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.29 The Mitochondrial Inner Membrane i-AAA Protease Complex (MIMP) Family
FMIGHEMP_00379 2.A.40.7.7 82.3 6.1e-196 10 448 0.9799 0.9670 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.40 The Nucleobase/Ascorbate Transporter (NAT) or Nucleobase:Cation Symporter-2 (NCS2) Family
FMIGHEMP_00396 2.A.64.1.1 72.6 6.7e-102 1 259 0.9923 2.8989 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.64 The Twin Arginine Targeting (Tat) Family
FMIGHEMP_00405 2.A.38.1.1 83.6 5.5e-235 1 483 1.0000 1.0546 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.38 The K+ Transporter (Trk) Family
FMIGHEMP_00418 2.A.117.1.4 70.7 1e-54 1 140 0.9589 0.9524 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.117 The Chlorhexadine Exporter (CHX) Family
FMIGHEMP_00422 2.A.1.8.1 77.3 1.2e-210 1 463 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.1 The Major Facilitator Superfamily (MFS)
FMIGHEMP_00423 5.A.3.1.1 79.3 0 1 1241 0.9904 5.5067 5 Transmembrane Electron Carriers 5.A Transmembrane 2-electron transfer carriers 5.A.3 The Prokaryotic Molybdopterin-containing Oxidoreductase (PMO) Family
FMIGHEMP_00424 5.A.3.1.1 84.8 5.3e-268 1 506 0.9787 2.2578 5 Transmembrane Electron Carriers 5.A Transmembrane 2-electron transfer carriers 5.A.3 The Prokaryotic Molybdopterin-containing Oxidoreductase (PMO) Family
FMIGHEMP_00426 5.A.3.1.1 77.3 1.4e-100 1 225 1.0000 1.0000 5 Transmembrane Electron Carriers 5.A Transmembrane 2-electron transfer carriers 5.A.3 The Prokaryotic Molybdopterin-containing Oxidoreductase (PMO) Family
FMIGHEMP_00430 3.D.1.9.2 72.8 3.7e-251 1 556 0.9964 2.1843 3 Primary Active Transporters 3.D Oxidoreduction-driven transporters 3.D.1 The H+ or Na+-translocating NADH Dehydrogenase (NDH) Family
FMIGHEMP_00436 2.A.7.1.4 75 3.5e-38 1 104 1.0000 0.9905 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.7 The Drug/Metabolite Transporter (DMT) Superfamily
FMIGHEMP_00443 2.A.1.4.3 86.8 2.2e-238 1 448 0.9956 0.9912 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.1 The Major Facilitator Superfamily (MFS)
FMIGHEMP_00448 2.A.88.8.6 74 7.8e-83 4 207 0.9107 0.9231 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.88 The Vitamin Uptake Transporter (VUT) Family
FMIGHEMP_00479 2.A.21.1.1 78.3 1.2e-210 3 482 0.9938 0.9917 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.21 The Solute:Sodium Symporter (SSS) Family
FMIGHEMP_00485 9.B.157.1.3 95.1 6.4e-185 1 347 1.0000 0.9455 9 Incompletely Characterized Transport Systems 9.B Putative transport proteins 9.B.157 The Cell Shape-determining MreBCD (MreBCD) Family
FMIGHEMP_00509 3.A.1.27.3 80 6.9e-118 7 266 0.9630 1.0359 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
FMIGHEMP_00510 3.A.1.27.3 80.7 2.6e-114 1 259 1.0000 1.0319 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
FMIGHEMP_00512 3.A.1.27.3 72 1.5e-83 1 209 1.0000 0.8406 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
FMIGHEMP_00525 1.A.12.3.1 81.3 1.4e-94 1 209 0.9812 0.9858 1 Channels/Pores 1.A α-Type Channels 1.A.12 The Intracellular Chloride Channel (CLIC) Family
FMIGHEMP_00554 9.B.27.2.2 71.6 3.4e-86 1 215 0.9685 0.9773 9 Incompletely Characterized Transport Systems 9.B Putative transport proteins 9.B.27 The Death Effector Domain A (DedA) Family
FMIGHEMP_00555 2.A.23.1.13 72.2 1.2e-153 12 411 0.9592 0.9662 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.23 The Dicarboxylate/Amino Acid:Cation (Na+ or H+) Symporter (DAACS) Family
FMIGHEMP_00582 1.A.33.1.2 87.2 2.20000000000008e-311 1 641 1.0000 1.0000 1 Channels/Pores 1.A α-Type Channels 1.A.33 The Cation Channel-forming Heat Shock Protein-70 (Hsp70) Family
FMIGHEMP_00602 3.D.7.2.5 79.9 3.1e-177 5 368 0.9733 0.9758 3 Primary Active Transporters 3.D Oxidoreduction-driven transporters 3.D.7 The H<sub>2</sub>:Heterodisulfide Oxidoreductase (HHO) Family
FMIGHEMP_00603 3.D.7.2.5 73.3 4.1e-152 1 337 1.0000 0.8817 3 Primary Active Transporters 3.D Oxidoreduction-driven transporters 3.D.7 The H<sub>2</sub>:Heterodisulfide Oxidoreductase (HHO) Family
FMIGHEMP_00604 3.D.7.2.5 71.3 1.2e-150 3 377 0.9542 1.0108 3 Primary Active Transporters 3.D Oxidoreduction-driven transporters 3.D.7 The H<sub>2</sub>:Heterodisulfide Oxidoreductase (HHO) Family
FMIGHEMP_00605 3.D.7.2.5 72.7 5.8e-252 1 567 1.0000 1.5242 3 Primary Active Transporters 3.D Oxidoreduction-driven transporters 3.D.7 The H<sub>2</sub>:Heterodisulfide Oxidoreductase (HHO) Family
FMIGHEMP_00612 9.B.102.1.1 78.2 5.4e-191 1 395 0.9681 0.9850 9 Incompletely Characterized Transport Systems 9.B Putative transport proteins 9.B.102 The YedE/YeeE (YedE/YeeE) Family
FMIGHEMP_00644 2.A.6.4.1 79 3.6e-268 1 604 1.0000 1.8700 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.6 The Resistance-Nodulation-Cell Division (RND) Superfamily
FMIGHEMP_00645 2.A.6.4.1 75.9 4.1e-133 1 322 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.6 The Resistance-Nodulation-Cell Division (RND) Superfamily
FMIGHEMP_00655 3.A.1.2.1 77.4 3.7e-125 1 296 1.0000 0.9221 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
FMIGHEMP_00656 3.A.1.2.1 84.7 6.2e-142 1 321 1.0000 0.9969 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
FMIGHEMP_00657 3.A.1.2.1 75.9 2.5e-214 1 494 0.9841 1.5389 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
FMIGHEMP_00670 3.D.4.5.1 73.5 8.4e-84 1 203 1.0000 1.8716 3 Primary Active Transporters 3.D Oxidoreduction-driven transporters 3.D.4 The Proton-translocating Cytochrome Oxidase (COX) Superfamily
FMIGHEMP_00671 3.D.4.5.1 83 0 1 660 1.0000 6.0550 3 Primary Active Transporters 3.D Oxidoreduction-driven transporters 3.D.4 The Proton-translocating Cytochrome Oxidase (COX) Superfamily
FMIGHEMP_00696 2.A.6.2.2 76.1 0 1 1044 0.9924 0.9933 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.6 The Resistance-Nodulation-Cell Division (RND) Superfamily
FMIGHEMP_00707 2.A.114.1.10 89.3 0 1 716 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.114 The Putative Peptide Transporter Carbon Starvation CstA (CstA) Family
FMIGHEMP_00727 3.A.1.105.17 82.1 7.7e-137 1 302 0.9649 0.9805 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
FMIGHEMP_00728 3.A.1.105.17 76.2 1.6e-111 1 256 1.0000 0.8312 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
FMIGHEMP_00746 2.A.8.1.5 79.3 6.3e-193 1 445 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.8 The Gluconate:H+ Symporter (GntP) Family
FMIGHEMP_00749 3.A.1.20.2 70.8 1.9e-281 5 690 0.9913 1.9942 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
FMIGHEMP_00750 3.A.1.20.2 75.7 3.8e-145 14 342 0.9592 0.9709 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
FMIGHEMP_00799 2.A.17.1.3 77.9 5.7e-219 1 484 0.9837 0.9877 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.17 The Proton-dependent Oligopeptide Transporter (POT/PTR) Family
FMIGHEMP_00825 2.A.68.1.2 71.2 3.5e-211 2 519 0.9885 0.9904 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.68 The p-Aminobenzoyl-glutamate Transporter (AbgT) Family
FMIGHEMP_00851 2.A.3.2.1 82.3 6.7e-203 1 434 0.9819 0.9909 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.3 The Amino Acid-Polyamine-Organocation (APC) Family
FMIGHEMP_00897 3.D.5.1.1 77.4 3.8e-192 1 411 0.9976 1.9571 3 Primary Active Transporters 3.D Oxidoreduction-driven transporters 3.D.5 The Na+-translocating NADH:Quinone Dehydrogenase (Na-NDH or NQR) Family
FMIGHEMP_00899 3.D.5.1.1 77.8 1e-84 1 207 0.9904 0.9857 3 Primary Active Transporters 3.D Oxidoreduction-driven transporters 3.D.5 The Na+-translocating NADH:Quinone Dehydrogenase (Na-NDH or NQR) Family
FMIGHEMP_00900 3.D.5.1.1 84.3 2.4e-91 1 198 1.0000 0.9429 3 Primary Active Transporters 3.D Oxidoreduction-driven transporters 3.D.5 The Na+-translocating NADH:Quinone Dehydrogenase (Na-NDH or NQR) Family
FMIGHEMP_00901 3.D.5.1.1 79.8 8.6e-197 4 408 0.9926 1.9286 3 Primary Active Transporters 3.D Oxidoreduction-driven transporters 3.D.5 The Na+-translocating NADH:Quinone Dehydrogenase (Na-NDH or NQR) Family
FMIGHEMP_00929 1.A.112.2.5 71.4 4.3e-175 1 423 0.9976 0.9883 1 Channels/Pores 1.A α-Type Channels 1.A.112 The Cyclin M Mg2+ Exporter (CNNM) Family
FMIGHEMP_00931 3.A.5.1.1 87.6 4e-219 1 453 1.0000 2.1990 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.5 The General Secretory Pathway (Sec) Family
FMIGHEMP_00940 2.A.13.1.2 87.2 3e-219 2 447 0.9978 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.13 The C<sub>4</sub>-Dicarboxylate Uptake (Dcu) Family
FMIGHEMP_00958 2.A.1.3.2 72.7 7.3e-222 3 504 0.9941 0.9805 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.1 The Major Facilitator Superfamily (MFS)
FMIGHEMP_00966 3.A.1.12.1 73.9 2.4e-144 1 329 0.9940 0.9266 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
FMIGHEMP_00967 3.A.1.12.1 74.6 1.6e-142 55 406 0.8606 0.9859 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
FMIGHEMP_00968 3.A.1.12.1 73.1 9.7e-169 1 398 0.9975 1.1243 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
FMIGHEMP_00982 2.A.103.1.2 80.5 8.7e-172 1 370 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.103 The Bacterial Murein Precursor Exporter (MPE) Family
FMIGHEMP_00991 3.A.1.3.4 88.4 3.3e-119 1 241 1.0000 0.7980 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
FMIGHEMP_00992 3.A.1.3.4 84.3 1.1e-100 1 223 0.9955 0.7384 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
FMIGHEMP_00993 3.A.1.3.4 82.1 1.1e-114 1 246 1.0000 0.8146 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
FMIGHEMP_00994 3.A.1.3.4 75.5 6.4e-125 1 297 1.0000 1.0000 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
FMIGHEMP_01001 1.C.126.1.2 84.1 1.6e-136 1 289 0.9863 0.9932 1 Channels/Pores 1.C Pore-Forming Toxins (Proteins and Peptides) 1.C.126 The HlyC Haemolysin (HlyC) Family
FMIGHEMP_01130 3.D.4.3.2 80.8 5e-250 1 522 1.0000 14.1081 3 Primary Active Transporters 3.D Oxidoreduction-driven transporters 3.D.4 The Proton-translocating Cytochrome Oxidase (COX) Superfamily
FMIGHEMP_01138 1.A.30.2.2 83.2 7.6e-102 1 226 0.9912 1.5915 1 Channels/Pores 1.A α-Type Channels 1.A.30 The H+- or Na+-translocating Bacterial Flagellar Motor/ExbBD Outer Membrane Transport Energizer (Mot/Exb) Superfamily
FMIGHEMP_01139 1.A.30.2.2 75.7 2.9e-51 2 141 0.9929 0.9789 1 Channels/Pores 1.A α-Type Channels 1.A.30 The H+- or Na+-translocating Bacterial Flagellar Motor/ExbBD Outer Membrane Transport Energizer (Mot/Exb) Superfamily
FMIGHEMP_01141 2.C.1.2.1 75.4 2.1e-193 1 431 1.0000 1.6350 2 Electrochemical Potential-driven Transporters 2.C Ion-gradient-driven energizers 2.C.1 The TonB-ExbB-ExbD/TolA-TolQ-TolR Outer Membrane Receptor Energizers and Stabilizers (TonB/TolA) Family
FMIGHEMP_01160 3.A.1.8.1 76.2 1.1e-92 1 227 0.9870 0.8833 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
FMIGHEMP_01178 3.A.1.105.15 76.1 2e-152 1 368 0.9973 1.1054 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
FMIGHEMP_01179 3.A.1.105.15 71.7 1.1e-145 13 383 0.9687 1.1175 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
FMIGHEMP_01180 3.A.1.105.15 71.4 2.9e-238 8 580 0.9728 1.7259 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
FMIGHEMP_01185 1.E.43.1.1 75 1.1e-23 1 76 0.9268 0.9268 1 Channels/Pores 1.E Holins 1.E.43 The Putative Transglycosylase-associated Holin (T-A Hol) Family
FMIGHEMP_01206 2.A.122.1.1 74 2.2e-88 3 229 0.9742 0.9827 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.122 The LrgB/CidB Holin-like Glycolate/Glycerate Transporter (LrgB/CidB/GGT) Family
FMIGHEMP_01213 2.A.61.1.1 80 6.9e-195 2 451 0.9934 0.9761 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.61 The C<sub>4</sub>-dicarboxylate Uptake C (DcuC) Family
FMIGHEMP_01233 2.A.42.2.1 79.9 5.3e-192 1 432 0.9774 0.9953 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.42 The Hydroxy/Aromatic Amino Acid Permease (HAAAP) Family
FMIGHEMP_01242 3.A.1.3.3 71.3 5e-99 1 244 1.0000 0.9959 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
FMIGHEMP_01243 3.A.1.3.3 80.2 3e-107 8 249 0.9719 0.9959 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
FMIGHEMP_01267 1.A.16.1.1 71.5 5.6e-118 1 284 1.0000 0.9965 1 Channels/Pores 1.A α-Type Channels 1.A.16 The Formate-Nitrite Transporter (FNT) Family
FMIGHEMP_01278 3.A.1.106.1 80.3 6.4e-262 2 581 0.9983 0.9966 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
FMIGHEMP_01334 1.B.1.1.11 71.8 2.9e-151 1 371 1.0000 1.0000 1 Channels/Pores 1.B β-Barrel Porins 1.B.1 The General Bacterial Porin (GBP) Family
FMIGHEMP_01343 3.A.1.120.6 73.8 3.2e-270 1 642 0.9984 0.9984 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
FMIGHEMP_01411 2.A.3.1.2 85.9 2.5e-238 17 490 0.9576 0.9693 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.3 The Amino Acid-Polyamine-Organocation (APC) Family
FMIGHEMP_01413 2.A.3.1.14 72.7 8.2e-180 12 455 0.9673 0.9823 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.3 The Amino Acid-Polyamine-Organocation (APC) Family
FMIGHEMP_01604 1.B.25.1.19 74.9 7e-208 1 450 1.0000 1.0000 1 Channels/Pores 1.B β-Barrel Porins 1.B.25 The Outer Membrane Porin (Opr) Family
FMIGHEMP_01606 9.B.1.1.6 81.2 5.2e-127 1 292 1.0000 1.0000 9 Incompletely Characterized Transport Systems 9.B Putative transport proteins 9.B.1 The Integral Membrane CAAX Protease (CAAX Protease) Family
FMIGHEMP_01608 2.A.23.1.8 78 6.3e-196 1 460 0.9935 0.9935 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.23 The Dicarboxylate/Amino Acid:Cation (Na+ or H+) Symporter (DAACS) Family
FMIGHEMP_01614 3.A.1.15.4 82.1 8.3e-120 1 279 0.9208 0.9394 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
FMIGHEMP_01615 3.A.1.15.4 77.4 2.8e-128 6 293 0.9763 0.9697 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
FMIGHEMP_01616 3.A.1.15.4 75.4 1.7e-128 10 302 0.9702 0.9865 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
FMIGHEMP_01633 4.D.1.1.13 71.7 4.9e-134 1 325 0.9969 1.0000 4 Group Translocators 4.D Polysaccharide Synthase/Exporters 4.D.1 The Putative Vectorial Glycosyl Polymerization (VGP) Family
FMIGHEMP_01675 2.A.53.3.9 75.5 6.1e-233 1 559 0.9876 0.9894 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.53 The Sulfate Permease (SulP) Family
FMIGHEMP_01682 2.A.1.2.21 73.4 2.2e-168 1 398 0.9950 0.9900 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.1 The Major Facilitator Superfamily (MFS)
FMIGHEMP_01684 2.A.66.4.3 76.9 1.7e-221 1 511 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.66 The Multidrug/Oligosaccharidyl-lipid/Polysaccharide (MOP) Flippase Superfamily
FMIGHEMP_01712 3.A.1.15.5 78.1 1.9e-101 1 256 0.9808 0.9808 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
FMIGHEMP_01713 3.A.1.15.5 74.7 1.2e-100 1 237 0.9834 0.9080 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
FMIGHEMP_01721 2.A.7.1.9 70.6 4.2e-37 2 110 0.9909 0.9008 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.7 The Drug/Metabolite Transporter (DMT) Superfamily
FMIGHEMP_01727 4.C.1.1.4 77.1 9.2e-258 1 554 0.9858 0.9875 4 Group Translocators 4.C Acyl CoA ligase-coupled transporters 4.C.1 The Fatty Acid Group Translocation (FAT) Family
FMIGHEMP_01736 3.A.1.139.2 71 3.9e-94 1 252 0.9844 0.9730 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
FMIGHEMP_01760 3.D.2.1.1 83.5 1.8e-239 1 508 0.9980 1.1017 3 Primary Active Transporters 3.D Oxidoreduction-driven transporters 3.D.2 The Proton-translocating Transhydrogenase (PTH) Family
FMIGHEMP_01761 3.D.2.1.1 88.1 4.5e-226 1 462 1.0000 1.0000 3 Primary Active Transporters 3.D Oxidoreduction-driven transporters 3.D.2 The Proton-translocating Transhydrogenase (PTH) Family
FMIGHEMP_01788 3.A.1.105.16 75.4 0 9 917 0.9902 2.5324 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
FMIGHEMP_01789 3.A.1.105.16 74.9 2.7e-152 5 375 0.9893 1.0451 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
FMIGHEMP_01793 3.A.3.7.1 74.9 5.2e-279 2 685 0.9985 23.3793 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.3 The P-type ATPase (P-ATPase) Superfamily
FMIGHEMP_01799 5.A.3.3.2 82.9 7.6e-109 1 205 1.0000 0.7143 5 Transmembrane Electron Carriers 5.A Transmembrane 2-electron transfer carriers 5.A.3 The Prokaryotic Molybdopterin-containing Oxidoreductase (PMO) Family
FMIGHEMP_01800 5.A.3.3.2 79.8 0 9 813 0.9889 2.8049 5 Transmembrane Electron Carriers 5.A Transmembrane 2-electron transfer carriers 5.A.3 The Prokaryotic Molybdopterin-containing Oxidoreductase (PMO) Family
FMIGHEMP_01948 3.A.1.5.42 71.3 2.7e-225 38 549 0.9094 0.9360 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
FMIGHEMP_01949 3.A.1.5.5 70.1 1.3e-128 1 321 1.0000 1.1978 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
FMIGHEMP_01951 3.A.1.5.44 77.4 6.7e-155 1 328 0.9850 1.2193 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
FMIGHEMP_01952 3.A.1.5.5 71.9 2.2e-108 1 267 0.9926 0.9963 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
FMIGHEMP_01977 2.A.3.7.3 76.7 1.2e-216 1 508 0.9826 0.9961 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.3 The Amino Acid-Polyamine-Organocation (APC) Family
FMIGHEMP_02027 2.A.39.1.1 85.5 1.3e-195 1 406 0.9760 0.9690 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.39 The Nucleobase:Cation Symporter-1 (NCS1) Family
FMIGHEMP_02031 2.A.15.1.4 76.3 1.1e-305 1 679 0.9985 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.15 The Betaine/Carnitine/Choline Transporter (BCCT) Family
FMIGHEMP_02044 3.A.1.5.1 71.8 1.1e-234 1 543 0.9963 1.0074 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
FMIGHEMP_02054 2.A.95.1.7 71.2 3e-76 6 213 0.9720 0.9674 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.95 The 6 TMS Neutral Amino Acid Transporter (NAAT) Family
FMIGHEMP_02081 2.A.34.1.1 71.7 6.4e-197 1 512 0.9961 0.9961 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.34 The NhaB Na+:H+ Antiporter (NhaB) Family
FMIGHEMP_02102 1.A.13.5.1 71.8 2.2e-107 1 245 1.0000 0.9722 1 Channels/Pores 1.A α-Type Channels 1.A.13 The Epithelial Chloride Channel (E-ClC) Family
FMIGHEMP_02191 2.A.40.1.1 82.4 1.1e-189 1 420 0.9700 0.9790 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.40 The Nucleobase/Ascorbate Transporter (NAT) or Nucleobase:Cation Symporter-2 (NCS2) Family
FMIGHEMP_02202 2.A.17.1.2 72.7 9.3e-206 1 488 1.0000 0.9740 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.17 The Proton-dependent Oligopeptide Transporter (POT/PTR) Family
FMIGHEMP_02204 2.A.6.2.12 75.9 0 6 1028 0.9808 0.9980 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.6 The Resistance-Nodulation-Cell Division (RND) Superfamily
FMIGHEMP_02205 2.A.6.2.12 72.8 0 1 1018 0.9912 0.9932 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.6 The Resistance-Nodulation-Cell Division (RND) Superfamily
FMIGHEMP_02232 2.A.3.1.7 72.2 9.6e-192 17 469 0.9638 0.9617 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.3 The Amino Acid-Polyamine-Organocation (APC) Family
FMIGHEMP_02234 2.A.21.2.1 74.2 1.7e-210 1 493 0.9980 0.9821 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.21 The Solute:Sodium Symporter (SSS) Family
FMIGHEMP_02252 3.A.6.2.1 77.6 4.1e-195 1 449 0.9825 1.7045 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.6 The Type III (Virulence-related) Secretory Pathway (IIISP) Family
FMIGHEMP_02259 3.A.6.2.1 75.5 6e-95 16 256 0.9414 0.9129 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.6 The Type III (Virulence-related) Secretory Pathway (IIISP) Family
FMIGHEMP_02278 3.A.6.2.1 76.2 8.7e-298 1 694 0.9971 2.6212 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.6 The Type III (Virulence-related) Secretory Pathway (IIISP) Family
FMIGHEMP_02310 2.A.1.2.20 72 7e-159 9 397 0.9677 0.9534 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.1 The Major Facilitator Superfamily (MFS)
FMIGHEMP_02378 3.D.1.1.1 72.4 4.5e-258 1 611 1.0000 0.9984 3 Primary Active Transporters 3.D Oxidoreduction-driven transporters 3.D.1 The H+ or Na+-translocating NADH Dehydrogenase (NDH) Family
FMIGHEMP_02383 3.D.1.1.1 72.1 0 4 907 0.9934 1.4747 3 Primary Active Transporters 3.D Oxidoreduction-driven transporters 3.D.1 The H+ or Na+-translocating NADH Dehydrogenase (NDH) Family
FMIGHEMP_02384 3.D.1.1.1 84.1 3.5e-231 8 454 0.9846 0.7243 3 Primary Active Transporters 3.D Oxidoreduction-driven transporters 3.D.1 The H+ or Na+-translocating NADH Dehydrogenase (NDH) Family
FMIGHEMP_02386 3.D.1.1.1 85.1 0 1 598 1.0000 0.9723 3 Primary Active Transporters 3.D Oxidoreduction-driven transporters 3.D.1 The H+ or Na+-translocating NADH Dehydrogenase (NDH) Family
FMIGHEMP_02392 2.A.47.4.8 71.8 1.2e-242 1 609 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.47 The Divalent Anion:Na+ Symporter (DASS) Family
FMIGHEMP_02408 4.A.7.1.2 89 7e-210 1 418 1.0000 4.4000 4 Group Translocators 4.A Phosphotransfer-driven Group Translocators (PTS) 4.A.7 The PTS L-Ascorbate (L-Asc) Family
FMIGHEMP_02409 4.A.7.1.2 84.2 3.3e-38 2 96 0.9896 1.0000 4 Group Translocators 4.A Phosphotransfer-driven Group Translocators (PTS) 4.A.7 The PTS L-Ascorbate (L-Asc) Family
FMIGHEMP_02417 9.B.160.1.16 74.8 2.2e-63 1 159 0.9755 0.9815 9 Incompletely Characterized Transport Systems 9.B Putative transport proteins 9.B.160 The Colicin V Production (CvpA) Family
FMIGHEMP_02421 9.B.27.2.3 83 1.1e-100 9 226 0.9356 0.9954 9 Incompletely Characterized Transport Systems 9.B Putative transport proteins 9.B.27 The Death Effector Domain A (DedA) Family
FMIGHEMP_02447 5.A.3.5.1 71 0 1 759 1.0000 2.9843 5 Transmembrane Electron Carriers 5.A Transmembrane 2-electron transfer carriers 5.A.3 The Prokaryotic Molybdopterin-containing Oxidoreductase (PMO) Family
FMIGHEMP_02466 2.A.41.1.1 74.9 1.1e-159 1 392 0.9949 0.9950 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.41 The Concentrative Nucleoside Transporter (CNT) Family
FMIGHEMP_02471 8.A.8.1.1 87.1 2.5e-34 1 85 1.0000 1.0000 8 Accessory Factors Involved in Transport 8.A Auxiliary transport proteins 8.A.8 The Phosphotransferase System HPr (HPr) Family
FMIGHEMP_02472 8.A.7.1.1 77.9 6.3e-254 1 575 1.0000 1.0000 8 Accessory Factors Involved in Transport 8.A Auxiliary transport proteins 8.A.7 The Phosphotransferase System Enzyme I (EI) Family
FMIGHEMP_02476 3.A.1.6.1 72.1 2e-112 1 280 1.0000 1.0108 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
FMIGHEMP_02477 3.A.1.6.1 80.9 4.3e-123 1 277 1.0000 1.0000 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
FMIGHEMP_02641 2.A.21.3.2 75.8 7.4e-228 7 544 0.9890 0.9890 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.21 The Solute:Sodium Symporter (SSS) Family
FMIGHEMP_02712 1.B.20.1.2 99.3 0 1 561 1.0000 1.0000 1 Channels/Pores 1.B β-Barrel Porins 1.B.20 The Two-Partner Secretion (TPS) Family
FMIGHEMP_02716 3.A.5.1.1 83.8 0 1 901 0.9989 4.3689 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.5 The General Secretory Pathway (Sec) Family
FMIGHEMP_02726 2.A.103.1.1 75.7 4.6e-171 3 397 0.9950 0.9541 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.103 The Bacterial Murein Precursor Exporter (MPE) Family
FMIGHEMP_02728 9.B.146.1.6 88.3 6.9e-182 1 360 1.0000 1.0000 9 Incompletely Characterized Transport Systems 9.B Putative transport proteins 9.B.146 The Putative Undecaprenyl-phosphate N-Acetylglucosaminyl Transferase (MurG) Family
FMIGHEMP_02760 1.A.26.1.4 71.1 6.3e-135 1 357 1.0000 1.0000 1 Channels/Pores 1.A α-Type Channels 1.A.26 The Mg2+ Transporter-E (MgtE) Family
FMIGHEMP_02802 3.A.4.1.1 82.2 2.7e-193 1 426 0.9930 0.9930 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.4 The Arsenite-Antimonite (ArsAB) Efflux Family
FMIGHEMP_02824 8.A.21.2.2 81 2.6e-129 1 305 0.9935 0.9869 8 Accessory Factors Involved in Transport 8.A Auxiliary transport proteins 8.A.21 The Stomatin/Podocin/Band 7/Nephrosis.2/SPFH (Stomatin) Family
FMIGHEMP_02827 3.A.3.5.5 72.7 0 140 984 0.8587 0.9976 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.3 The P-type ATPase (P-ATPase) Superfamily
FMIGHEMP_02832 2.A.37.1.5 71.7 1.3e-214 1 559 0.9539 0.9803 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.37 The Monovalent Cation:Proton Antiporter-2 (CPA2) Family
FMIGHEMP_02906 2.A.3.1.9 71.6 4e-187 1 454 0.9978 0.9743 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.3 The Amino Acid-Polyamine-Organocation (APC) Family
FMIGHEMP_02917 3.A.1.24.1 75.2 2.6e-146 1 343 1.0000 1.5806 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
FMIGHEMP_02918 3.A.1.24.1 83.4 2.7e-96 1 217 1.0000 1.0000 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
FMIGHEMP_02919 3.A.1.24.1 78.6 2e-125 1 271 1.0000 1.2488 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
FMIGHEMP_02935 1.B.33.1.3 72.4 0 1 797 1.0000 2.0663 1 Channels/Pores 1.B β-Barrel Porins 1.B.33 The Outer Membrane Protein Insertion Porin (Bam Complex) (OmpIP) Family
FMIGHEMP_02950 4.A.1.1.1 81.1 2.7e-218 1 476 0.9896 0.9979 4 Group Translocators 4.A Phosphotransfer-driven Group Translocators (PTS) 4.A.1 The PTS Glucose-Glucoside (Glc) Family
FMIGHEMP_02983 3.A.1.19.1 70.1 1.7e-205 4 524 0.9905 1.5933 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
FMIGHEMP_02999 1.B.12.5.3 99.5 0 1 1084 1.0000 1.0000 1 Channels/Pores 1.B β-Barrel Porins 1.B.12 The Autotransporter-1 (AT-1) Family
FMIGHEMP_03021 9.B.31.1.1 78.7 1.2e-88 1 202 0.9266 0.9854 9 Incompletely Characterized Transport Systems 9.B Putative transport proteins 9.B.31 The PlsY/YqiH (PlsY) Family
FMIGHEMP_03050 2.A.109.1.1 88.5 3.7e-169 1 338 0.9912 0.9769 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.109 The Tellurium Ion Resistance (TerC) Family
FMIGHEMP_03083 2.A.41.2.11 71 3.3e-162 1 424 0.9792 0.9976 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.41 The Concentrative Nucleoside Transporter (CNT) Family
FMIGHEMP_03123 2.A.51.1.7 99.5 5.1e-210 1 376 0.9377 0.9666 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.51 The Chromate Ion Transporter (CHR) Family
FMIGHEMP_03147 2.A.1.2.110 98.3 3.4e-214 1 404 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.1 The Major Facilitator Superfamily (MFS)
FMIGHEMP_03164 2.A.1.2.102 99.2 1.1e-215 1 396 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.1 The Major Facilitator Superfamily (MFS)
FMIGHEMP_03231 4.B.1.1.1 82 1.3e-200 1 406 0.9807 1.6987 4 Group Translocators 4.B Nicotinamide ribonucleoside uptake transporters 4.B.1 The Nicotinamide Ribonucleoside (NR) Uptake Permease (PnuC) Family
FMIGHEMP_03248 3.D.1.9.1 78.1 2e-271 16 577 0.9740 1.7333 3 Primary Active Transporters 3.D Oxidoreduction-driven transporters 3.D.1 The H+ or Na+-translocating NADH Dehydrogenase (NDH) Family
FMIGHEMP_03251 3.D.1.9.1 70.7 1.4e-190 1 478 0.9979 1.5175 3 Primary Active Transporters 3.D Oxidoreduction-driven transporters 3.D.1 The H+ or Na+-translocating NADH Dehydrogenase (NDH) Family
FMIGHEMP_03252 3.D.1.9.1 70.1 3e-112 14 317 0.9590 0.9651 3 Primary Active Transporters 3.D Oxidoreduction-driven transporters 3.D.1 The H+ or Na+-translocating NADH Dehydrogenase (NDH) Family
FMIGHEMP_03274 2.A.13.1.1 82.8 6.5e-190 1 441 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.13 The C<sub>4</sub>-Dicarboxylate Uptake (Dcu) Family
FMIGHEMP_03294 2.A.1.1.114 77.4 1.5e-199 1 437 0.9932 0.9887 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.1 The Major Facilitator Superfamily (MFS)
FMIGHEMP_03299 2.A.15.2.2 100 7.4e-299 1 504 1.0000 0.9805 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.15 The Betaine/Carnitine/Choline Transporter (BCCT) Family
FMIGHEMP_03302 4.C.1.1.6 71.8 3.2e-228 1 518 1.0000 1.0000 4 Group Translocators 4.C Acyl CoA ligase-coupled transporters 4.C.1 The Fatty Acid Group Translocation (FAT) Family
FMIGHEMP_03318 2.A.8.1.8 77.1 3.7e-193 1 445 1.0000 0.9978 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.8 The Gluconate:H+ Symporter (GntP) Family
FMIGHEMP_03329 1.C.36.3.4 99.9 0 1 719 1.0000 1.0000 1 Channels/Pores 1.C Pore-Forming Toxins (Proteins and Peptides) 1.C.36 The Bacterial Type III-Target Cell Pore (IIITCP) Family
FMIGHEMP_03354 2.A.6.2.32 77.1 0 1 1021 0.9961 6.8986 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.6 The Resistance-Nodulation-Cell Division (RND) Superfamily
FMIGHEMP_03366 1.S.1.1.11 83.5 2.5e-35 1 91 0.9891 0.9681 1 Channels/Pores 1.S Bacterial Micro/NanoCompartment Shell Protein Pores 1.S.1 The Bacterial Microcompartment Shell/Pore-forming Protein-1 (BMC-SP1) Family
FMIGHEMP_03367 1.S.1.1.11 88.3 9e-41 1 94 1.0000 1.0000 1 Channels/Pores 1.S Bacterial Micro/NanoCompartment Shell Protein Pores 1.S.1 The Bacterial Microcompartment Shell/Pore-forming Protein-1 (BMC-SP1) Family
FMIGHEMP_03368 1.S.1.1.11 94.5 5.2e-41 1 91 0.9891 0.9681 1 Channels/Pores 1.S Bacterial Micro/NanoCompartment Shell Protein Pores 1.S.1 The Bacterial Microcompartment Shell/Pore-forming Protein-1 (BMC-SP1) Family
FMIGHEMP_03380 3.A.1.11.1 78.7 3.3e-165 1 347 1.0000 0.9206 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
FMIGHEMP_03382 3.A.1.11.1 82.9 5e-127 12 286 0.9615 0.7275 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
FMIGHEMP_03383 3.A.1.11.1 80.4 3.7e-170 3 370 0.9919 0.9735 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
FMIGHEMP_03392 2.A.42.2.4 84.3 9.3e-205 1 443 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.42 The Hydroxy/Aromatic Amino Acid Permease (HAAAP) Family
FMIGHEMP_03496 3.A.1.5.27 76.9 5.1e-139 4 327 0.9730 1.0949 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
FMIGHEMP_03497 3.A.1.5.27 74.4 3.2e-141 1 324 0.9908 1.0983 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
FMIGHEMP_03515 1.A.62.2.3 72.1 2.2e-76 1 204 0.9951 0.9902 1 Channels/Pores 1.A α-Type Channels 1.A.62 The Homotrimeric Cation Channel (TRIC) Family
FMIGHEMP_03521 2.A.27.1.1 78.2 1.5e-169 1 399 0.9876 0.9950 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.27 The Glutamate:Na+ Symporter (ESS) Family
FMIGHEMP_03522 2.A.40.4.2 82.2 6.8e-206 10 463 0.9806 0.9827 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.40 The Nucleobase/Ascorbate Transporter (NAT) or Nucleobase:Cation Symporter-2 (NCS2) Family
FMIGHEMP_03543 3.A.1.7.1 77.5 6.3e-156 1 346 1.0000 1.0846 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
FMIGHEMP_03544 3.A.1.7.1 85.3 1.8e-149 1 319 1.0000 1.0000 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
FMIGHEMP_03545 3.A.1.7.1 82.9 3.1e-135 9 300 0.9733 0.9185 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
FMIGHEMP_03546 3.A.1.7.1 92.1 7.7e-135 6 258 0.9806 0.7931 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
FMIGHEMP_03565 2.A.40.7.6 77.6 2.1e-183 11 444 0.9602 0.9753 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.40 The Nucleobase/Ascorbate Transporter (NAT) or Nucleobase:Cation Symporter-2 (NCS2) Family
FMIGHEMP_03571 9.A.8.1.1 71.7 0 1 776 1.0000 1.0000 9 Incompletely Characterized Transport Systems 9.A Recognized transporters of unknown biochemical mechanism 9.A.8 The Ferrous Iron Uptake (FeoB) Family
FMIGHEMP_03604 4.A.3.2.1 73 5e-41 1 115 1.0000 1.0849 4 Group Translocators 4.A Phosphotransfer-driven Group Translocators (PTS) 4.A.3 The PTS Lactose-N,N'-Diacetylchitobiose-β-glucoside (Lac) Family
FMIGHEMP_03605 4.A.3.2.1 88.7 7.2e-229 1 452 1.0000 4.2642 4 Group Translocators 4.A Phosphotransfer-driven Group Translocators (PTS) 4.A.3 The PTS Lactose-N,N'-Diacetylchitobiose-β-glucoside (Lac) Family
FMIGHEMP_03606 4.A.3.2.1 87.6 1.1e-45 1 105 0.9722 0.9906 4 Group Translocators 4.A Phosphotransfer-driven Group Translocators (PTS) 4.A.3 The PTS Lactose-N,N'-Diacetylchitobiose-β-glucoside (Lac) Family
FMIGHEMP_03626 2.A.21.3.10 84.1 3.7e-234 1 490 0.9879 0.9839 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.21 The Solute:Sodium Symporter (SSS) Family
FMIGHEMP_03659 2.A.20.1.1 72.3 1.6e-200 14 509 0.9688 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.20 The Inorganic Phosphate Transporter (PiT) Family
FMIGHEMP_03686 2.A.21.7.2 80.3 7.7e-233 20 551 0.9655 0.9672 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.21 The Solute:Sodium Symporter (SSS) Family
FMIGHEMP_03706 3.A.2.1.1 81.2 9.4e-123 4 274 0.9891 3.4177 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.2 The H+- or Na+-translocating F-type, V-type and A-type ATPase (F-ATPase) Superfamily
FMIGHEMP_03707 3.A.2.1.1 97.5 3.1e-34 1 79 1.0000 1.0000 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.2 The H+- or Na+-translocating F-type, V-type and A-type ATPase (F-ATPase) Superfamily
FMIGHEMP_03708 3.A.2.1.1 87.8 4.3e-64 1 156 1.0000 1.9747 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.2 The H+- or Na+-translocating F-type, V-type and A-type ATPase (F-ATPase) Superfamily
FMIGHEMP_03709 3.A.2.1.1 75.1 3.6e-67 1 177 1.0000 2.2405 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.2 The H+- or Na+-translocating F-type, V-type and A-type ATPase (F-ATPase) Superfamily
FMIGHEMP_03710 3.A.2.1.1 91.8 2e-267 1 513 1.0000 6.4937 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.2 The H+- or Na+-translocating F-type, V-type and A-type ATPase (F-ATPase) Superfamily
FMIGHEMP_03711 3.A.2.1.1 87.1 9.8e-139 1 287 1.0000 3.6329 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.2 The H+- or Na+-translocating F-type, V-type and A-type ATPase (F-ATPase) Superfamily
FMIGHEMP_03712 3.A.2.1.1 93.9 2.4e-248 1 460 1.0000 5.8228 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.2 The H+- or Na+-translocating F-type, V-type and A-type ATPase (F-ATPase) Superfamily
FMIGHEMP_03713 3.A.2.1.1 78.4 3.6e-54 5 138 0.9710 1.6962 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.2 The H+- or Na+-translocating F-type, V-type and A-type ATPase (F-ATPase) Superfamily
FMIGHEMP_03765 5.A.3.2.1 76.6 0 1 802 0.9988 0.7901 5 Transmembrane Electron Carriers 5.A Transmembrane 2-electron transfer carriers 5.A.3 The Prokaryotic Molybdopterin-containing Oxidoreductase (PMO) Family