Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1406
  Reference Plasmid   NZ_OP038276.1
  Reference Plasmid Size   88949
  Reference Plasmid GC Content   0.52
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0208992 NNOANBKH_00034 33410 9 Gut 0.56 protein_coding missense_variant MODERATE 125A>T Gln42Leu
M0208993 NNOANBKH_00043 39889 13 Gut 0.81 protein_coding synonymous_variant LOW 3204G>A Glu1068Glu
M0208994 NNOANBKH_00043 39998 11 Gut 0.69 protein_coding missense_variant MODERATE 3095T>A Val1032Glu
M0208995 NNOANBKH_00043 40069 11 Gut 0.69 protein_coding missense_variant MODERATE 3024C>A His1008Gln
M0208996 NNOANBKH_00043 40293 11 Gut 0.69 protein_coding missense_variant MODERATE 2800C>A Leu934Ile
M0208997 NNOANBKH_00043 40861 14 Gut 0.88 protein_coding synonymous_variant LOW 2232G>T Val744Val
M0208998 NNOANBKH_00051 50294 14 Gut 0.88 protein_coding missense_variant MODERATE 280G>A Val94Ile
M0208999 NNOANBKH_00051 50562 14 Gut 0.88 protein_coding missense_variant MODERATE 12G>A Met4Ile
M0209000 NNOANBKH_00055 54242 14 Gut 0.88 protein_coding missense_variant MODERATE 80G>A Arg27His
M0209001 NNOANBKH_00055 54280 14 Gut 0.88 protein_coding missense_variant MODERATE 42T>A Asp14Glu
M0209002 NNOANBKH_00050 54403 14 Gut 0.88 protein_coding upstream_gene_variant MODIFIER -4474G>C None
M0209003 NNOANBKH_00056 54542 14 Gut 0.88 protein_coding missense_variant MODERATE 341G>A Arg114Gln
M0209004 NNOANBKH_00056 54547 11 Gut 0.69 protein_coding synonymous_variant LOW 336C>T Gly112Gly
M0209005 NNOANBKH_00056 54580 14 Gut 0.88 protein_coding missense_variant MODERATE 303G>C Gln101His
M0209006 NNOANBKH_00057 56141 14 Gut 0.88 protein_coding synonymous_variant LOW 27C>A Arg9Arg
M0209007 NNOANBKH_00057 56162 14 Gut 0.88 protein_coding synonymous_variant LOW 6G>A Thr2Thr
M0209008 NNOANBKH_00058 56467 14 Gut 0.88 protein_coding synonymous_variant LOW 1341A>G Gln447Gln
M0209009 NNOANBKH_00060 58293 11 Gut 0.69 protein_coding missense_variant MODERATE 1058G>A Arg353His
M0209010 NNOANBKH_00060 58566 14 Gut 0.88 protein_coding missense_variant MODERATE 785C>A Pro262Gln
M0209011 NNOANBKH_00060 58706 14 Gut 0.88 protein_coding synonymous_variant LOW 645A>C Thr215Thr
M0209012 NNOANBKH_00066 64208 11 Gut 0.69 protein_coding synonymous_variant LOW 195T>C Gly65Gly
M0209013 NNOANBKH_00061 64466 11 Gut 0.69 protein_coding upstream_gene_variant MODIFIER -4555G>A None
M0209014 NNOANBKH_00061 64525 11 Gut 0.69 protein_coding upstream_gene_variant MODIFIER -4614C>T None
M0209015 NNOANBKH_00061 64573 14 Gut 0.88 protein_coding upstream_gene_variant MODIFIER -4662G>A None
M0209016 NNOANBKH_00061 64580 14 Gut 0.88 protein_coding upstream_gene_variant MODIFIER -4669G>A None
M0209017 NNOANBKH_00061 64763 11 Gut 0.69 protein_coding upstream_gene_variant MODIFIER -4852C>G None
M0209018 NNOANBKH_00061 64806 11 Gut 0.69 protein_coding upstream_gene_variant MODIFIER -4895C>A None
M0209019 NNOANBKH_00061 64877 11 Gut 0.69 protein_coding upstream_gene_variant MODIFIER -4966A>G None
M0209020 NNOANBKH_00061 64907 11 Gut 0.69 protein_coding upstream_gene_variant MODIFIER -4996C>A None
M0209021 NNOANBKH_00062 64946 11 Gut 0.69 protein_coding upstream_gene_variant MODIFIER -4677T>C None
M0209022 NNOANBKH_00062 65002 11 Gut 0.69 protein_coding upstream_gene_variant MODIFIER -4733G>A None
M0209023 NNOANBKH_00062 65003 11 Gut 0.69 protein_coding upstream_gene_variant MODIFIER -4734G>T None
M0209024 NNOANBKH_00062 65008 11 Gut 0.69 protein_coding upstream_gene_variant MODIFIER -4739T>C None
M0209025 NNOANBKH_00062 65019 11 Gut 0.69 protein_coding upstream_gene_variant MODIFIER -4750A>G None
M0209026 NNOANBKH_00062 65056 11 Gut 0.69 protein_coding upstream_gene_variant MODIFIER -4787A>G None
M0209027 NNOANBKH_00067 65131 11 Gut 0.69 protein_coding synonymous_variant LOW 27T>C Phe9Phe
M0209028 NNOANBKH_00067 65923 11 Gut 0.69 protein_coding synonymous_variant LOW 819C>A Arg273Arg
M0209029 NNOANBKH_00063 66481 11 Gut 0.69 protein_coding upstream_gene_variant MODIFIER -4437C>T None
M0209030 NNOANBKH_00063 66535 14 Gut 0.88 protein_coding upstream_gene_variant MODIFIER -4491C>T None
M0209031 NNOANBKH_00063 66589 11 Gut 0.69 protein_coding upstream_gene_variant MODIFIER -4545C>G None
M0209032 NNOANBKH_00063 66669 14 Gut 0.88 protein_coding upstream_gene_variant MODIFIER -4625G>C None
M0209033 NNOANBKH_00063 66690 14 Gut 0.88 protein_coding upstream_gene_variant MODIFIER -4646T>C None
M0209034 NNOANBKH_00063 66692 14 Gut 0.88 protein_coding upstream_gene_variant MODIFIER -4648A>G None
M0209035 NNOANBKH_00063 66693 14 Gut 0.88 protein_coding upstream_gene_variant MODIFIER -4649G>A None
M0209036 NNOANBKH_00063 66695 14 Gut 0.88 protein_coding upstream_gene_variant MODIFIER -4651C>T None
M0209037 NNOANBKH_00063 66703 14 Gut 0.88 protein_coding upstream_gene_variant MODIFIER -4659T>A None
M0209038 NNOANBKH_00063 66704 14 Gut 0.88 protein_coding upstream_gene_variant MODIFIER -4660T>C None
M0209039 NNOANBKH_00063 66743 14 Gut 0.88 protein_coding upstream_gene_variant MODIFIER -4699C>A None
M0209040 NNOANBKH_00063 66764 14 Gut 0.88 protein_coding upstream_gene_variant MODIFIER -4720A>G None
M0209041 NNOANBKH_00063 66786 14 Gut 0.88 protein_coding upstream_gene_variant MODIFIER -4742A>T None
M0209042 NNOANBKH_00063 66793 14 Gut 0.88 protein_coding upstream_gene_variant MODIFIER -4749T>C None
M0209043 NNOANBKH_00063 66832 14 Gut 0.88 protein_coding upstream_gene_variant MODIFIER -4788G>A None
M0209044 NNOANBKH_00063 66870 14 Gut 0.88 protein_coding upstream_gene_variant MODIFIER -4826C>T None
M0209045 NNOANBKH_00068 66908 14 Gut 0.88 protein_coding synonymous_variant LOW 21A>G Gln7Gln
M0209046 NNOANBKH_00068 66976 14 Gut 0.88 protein_coding missense_variant MODERATE 89A>G Lys30Arg
M0209047 NNOANBKH_00068 66977 14 Gut 0.88 protein_coding synonymous_variant LOW 90A>G Lys30Lys
M0209048 NNOANBKH_00068 66995 14 Gut 0.88 protein_coding synonymous_variant LOW 108T>C Gly36Gly
M0209049 NNOANBKH_00068 67043 14 Gut 0.88 protein_coding synonymous_variant LOW 156A>G Glu52Glu
M0209050 NNOANBKH_00068 67094 11 Gut 0.69 protein_coding synonymous_variant LOW 207T>C Val69Val
M0209051 NNOANBKH_00069 67231 14 Gut 0.88 protein_coding synonymous_variant LOW 66A>G Leu22Leu
M0209052 NNOANBKH_00069 67246 14 Gut 0.88 protein_coding synonymous_variant LOW 81T>G Ala27Ala
M0209053 NNOANBKH_00069 67261 14 Gut 0.88 protein_coding synonymous_variant LOW 96A>G Val32Val
M0209054 NNOANBKH_00069 67264 14 Gut 0.88 protein_coding synonymous_variant LOW 99G>A Gln33Gln
M0209055 NNOANBKH_00069 67276 14 Gut 0.88 protein_coding synonymous_variant LOW 111A>G Gln37Gln
M0209056 NNOANBKH_00069 67333 14 Gut 0.88 protein_coding synonymous_variant LOW 168G>A Glu56Glu
M0209057 NNOANBKH_00069 67343 14 Gut 0.88 protein_coding missense_variant MODERATE 178A>G Ile60Val
M0209058 NNOANBKH_00065 67940 11 Gut 0.69 protein_coding upstream_gene_variant MODIFIER -4320A>G None
M0209059 NNOANBKH_00065 67967 14 Gut 0.88 protein_coding upstream_gene_variant MODIFIER -4347A>G None
M0209060 NNOANBKH_00071 68242 14 Gut 0.88 protein_coding synonymous_variant LOW 48A>G Val16Val
M0209061 NNOANBKH_00073 68790 7 Gut 0.44 protein_coding synonymous_variant LOW 348T>A Ile116Ile
M0209062 NNOANBKH_00073 69105 9 Gut 0.56 protein_coding synonymous_variant LOW 33G>C Pro11Pro
M0209063 NNOANBKH_00073 69128 9 Gut 0.56 protein_coding missense_variant MODERATE 10T>A Tyr4Asn
M0209064 NNOANBKH_00042 38742 4 Gut 0.25 protein_coding synonymous_variant LOW 273A>G Gln91Gln
M0209065 NNOANBKH_00065 68465 6 Gut 0.38 protein_coding upstream_gene_variant MODIFIER -4845T>C None
M0209066 NNOANBKH_00073 69070 3 Gut 0.19 protein_coding missense_variant MODERATE 68C>T Pro23Leu
M0209067 NNOANBKH_00014 13382 3 Gut 0.19 protein_coding synonymous_variant LOW 1683T>C Ala561Ala
M0209068 NNOANBKH_00014 14477 3 Gut 0.19 protein_coding synonymous_variant LOW 588A>G Glu196Glu
M0209069 NNOANBKH_00014 14699 3 Gut 0.19 protein_coding synonymous_variant LOW 366C>T Asn122Asn
M0209070 NNOANBKH_00014 14735 3 Gut 0.19 protein_coding synonymous_variant LOW 330C>A Ala110Ala
M0209071 NNOANBKH_00014 14742 3 Gut 0.19 protein_coding missense_variant MODERATE 323T>C Phe108Ser
M0209072 NNOANBKH_00014 14753 3 Gut 0.19 protein_coding synonymous_variant LOW 312G>A Ala104Ala
M0209073 NNOANBKH_00014 14797 3 Gut 0.19 protein_coding synonymous_variant LOW 268A>C Arg90Arg
M0209074 NNOANBKH_00014 14837 3 Gut 0.19 protein_coding synonymous_variant LOW 228A>G Thr76Thr
M0209075 NNOANBKH_00014 14877 3 Gut 0.19 protein_coding missense_variant MODERATE 188T>C Met63Thr
M0209076 NNOANBKH_00014 14912 3 Gut 0.19 protein_coding synonymous_variant LOW 153C>T Cys51Cys
M0209077 NNOANBKH_00014 14942 3 Gut 0.19 protein_coding synonymous_variant LOW 123G>C Ala41Ala
M0209078 NNOANBKH_00014 14976 3 Gut 0.19 protein_coding missense_variant MODERATE 89C>T Thr30Ile
M0209079 NNOANBKH_00014 15007 3 Gut 0.19 protein_coding synonymous_variant LOW 58T>C Leu20Leu
M0209080 NNOANBKH_00015 15751 3 Gut 0.19 protein_coding missense_variant MODERATE 419C>A Thr140Lys
M0209081 NNOANBKH_00015 15866 3 Gut 0.19 protein_coding missense_variant MODERATE 304A>T Asn102Tyr
M0209082 NNOANBKH_00015 16071 3 Gut 0.19 protein_coding synonymous_variant LOW 99C>A Val33Val
M0209083 NNOANBKH_00015 16074 3 Gut 0.19 protein_coding synonymous_variant LOW 96A>G Pro32Pro
M0209084 NNOANBKH_00015 16120 3 Gut 0.19 protein_coding missense_variant MODERATE 50T>C Ile17Thr
M0209085 NNOANBKH_00013 17571 3 Gut 0.19 protein_coding upstream_gene_variant MODIFIER -4924A>G None
M0209086 NNOANBKH_00014 17701 3 Gut 0.19 protein_coding upstream_gene_variant MODIFIER -2637T>C None
M0209087 NNOANBKH_00017 18090 3 Gut 0.19 protein_coding synonymous_variant LOW 63A>T Ala21Ala
M0209088 NNOANBKH_00017 18091 3 Gut 0.19 protein_coding missense_variant MODERATE 64A>C Ile22Leu
M0209089 NNOANBKH_00014 18262 3 Gut 0.19 protein_coding upstream_gene_variant MODIFIER -3198A>C None
M0209090 NNOANBKH_00014 18296 3 Gut 0.19 protein_coding upstream_gene_variant MODIFIER -3232T>A None
M0209091 NNOANBKH_00014 19133 3 Gut 0.19 protein_coding upstream_gene_variant MODIFIER -4069G>A None
M0209092 NNOANBKH_00019 19610 3 Gut 0.19 protein_coding synonymous_variant LOW 54C>T Ala18Ala
M0209093 NNOANBKH_00020 20082 3 Gut 0.19 protein_coding synonymous_variant LOW 318C>T Val106Val
M0209094 NNOANBKH_00020 20186 3 Gut 0.19 protein_coding missense_variant MODERATE 422T>C Val141Ala
M0209095 NNOANBKH_00023 21197 3 Gut 0.19 protein_coding missense_variant MODERATE 34A>G Thr12Ala
M0209096 NNOANBKH_00023 21209 3 Gut 0.19 protein_coding missense_variant MODERATE 22G>T Ala8Ser
M0209097 NNOANBKH_00016 21311 3 Gut 0.19 protein_coding upstream_gene_variant MODIFIER -3820T>A None
M0209098 NNOANBKH_00016 21314 3 Gut 0.19 protein_coding upstream_gene_variant MODIFIER -3823C>T None
M0209099 NNOANBKH_00016 21475 3 Gut 0.19 protein_coding upstream_gene_variant MODIFIER -3984A>T None
M0209100 NNOANBKH_00016 21486 3 Gut 0.19 protein_coding upstream_gene_variant MODIFIER -3995C>T None
M0209101 NNOANBKH_00016 21495 3 Gut 0.19 protein_coding upstream_gene_variant MODIFIER -4004C>T None
M0209102 NNOANBKH_00016 21496 3 Gut 0.19 protein_coding upstream_gene_variant MODIFIER -4005T>A None
M0209103 NNOANBKH_00016 21509 3 Gut 0.19 protein_coding upstream_gene_variant MODIFIER -4018C>T None
M0209104 NNOANBKH_00024 21543 3 Gut 0.19 protein_coding missense_variant MODERATE 221A>G Lys74Arg
M0209105 NNOANBKH_00024 21664 3 Gut 0.19 protein_coding missense_variant MODERATE 100A>G Thr34Ala
M0209106 NNOANBKH_00024 21668 3 Gut 0.19 protein_coding synonymous_variant LOW 96G>A Ala32Ala
M0209107 NNOANBKH_00024 21695 3 Gut 0.19 protein_coding synonymous_variant LOW 69T>C Asn23Asn
M0209108 NNOANBKH_00016 21777 3 Gut 0.19 protein_coding upstream_gene_variant MODIFIER -4286G>A None
M0209109 NNOANBKH_00016 21916 3 Gut 0.19 protein_coding upstream_gene_variant MODIFIER -4425T>A None
M0209110 NNOANBKH_00016 22041 3 Gut 0.19 protein_coding upstream_gene_variant MODIFIER -4550T>G None
M0209111 NNOANBKH_00016 22042 3 Gut 0.19 protein_coding upstream_gene_variant MODIFIER -4551C>T None
M0209112 NNOANBKH_00016 22090 3 Gut 0.19 protein_coding upstream_gene_variant MODIFIER -4599T>C None
M0209113 NNOANBKH_00025 22210 3 Gut 0.19 protein_coding missense_variant MODERATE 118T>C Phe40Leu
M0209114 NNOANBKH_00016 22261 3 Gut 0.19 protein_coding upstream_gene_variant MODIFIER -4770G>A None
M0209115 NNOANBKH_00016 22264 3 Gut 0.19 protein_coding upstream_gene_variant MODIFIER -4773C>T None
M0209116 NNOANBKH_00016 22265 3 Gut 0.19 protein_coding upstream_gene_variant MODIFIER -4774T>C None
M0209117 NNOANBKH_00016 22266 3 Gut 0.19 protein_coding upstream_gene_variant MODIFIER -4775G>T None
M0209118 NNOANBKH_00026 22408 3 Gut 0.19 protein_coding missense_variant MODERATE 488C>T Pro163Leu
M0209119 NNOANBKH_00026 22525 3 Gut 0.19 protein_coding missense_variant MODERATE 371A>G Gln124Arg
M0209120 NNOANBKH_00027 23228 3 Gut 0.19 protein_coding synonymous_variant LOW 738C>T Ile246Ile
M0209121 NNOANBKH_00027 23753 3 Gut 0.19 protein_coding synonymous_variant LOW 213C>T Asp71Asp
M0209122 NNOANBKH_00028 24602 3 Gut 0.19 protein_coding synonymous_variant LOW 291G>A Pro97Pro
M0209123 NNOANBKH_00028 24605 3 Gut 0.19 protein_coding synonymous_variant LOW 288G>T Ala96Ala
M0209124 NNOANBKH_00028 24612 3 Gut 0.19 protein_coding missense_variant MODERATE 281C>A Pro94His
M0209125 NNOANBKH_00028 24616 3 Gut 0.19 protein_coding missense_variant MODERATE 277A>T Ser93Cys
M0209126 NNOANBKH_00029 25331 3 Gut 0.19 protein_coding synonymous_variant LOW 1815A>G Ser605Ser
M0209127 NNOANBKH_00029 25346 3 Gut 0.19 protein_coding synonymous_variant LOW 1800G>A Gly600Gly
M0209128 NNOANBKH_00029 25385 3 Gut 0.19 protein_coding synonymous_variant LOW 1761T>G Leu587Leu
M0209129 NNOANBKH_00029 25406 3 Gut 0.19 protein_coding synonymous_variant LOW 1740C>T Ala580Ala
M0209130 NNOANBKH_00029 25420 3 Gut 0.19 protein_coding synonymous_variant LOW 1726C>A Arg576Arg
M0209131 NNOANBKH_00029 25427 3 Gut 0.19 protein_coding synonymous_variant LOW 1719T>C Ser573Ser
M0209132 NNOANBKH_00029 25559 3 Gut 0.19 protein_coding synonymous_variant LOW 1587T>C Gly529Gly
M0209133 NNOANBKH_00029 25568 3 Gut 0.19 protein_coding synonymous_variant LOW 1578T>C Phe526Phe
M0209134 NNOANBKH_00029 25688 3 Gut 0.19 protein_coding synonymous_variant LOW 1458G>A Thr486Thr
M0209135 NNOANBKH_00029 26042 3 Gut 0.19 protein_coding synonymous_variant LOW 1104T>C Thr368Thr
M0209136 NNOANBKH_00029 26048 3 Gut 0.19 protein_coding synonymous_variant LOW 1098T>C Ala366Ala
M0209137 NNOANBKH_00029 26254 3 Gut 0.19 protein_coding synonymous_variant LOW 892T>C Leu298Leu
M0209138 NNOANBKH_00029 26351 3 Gut 0.19 protein_coding synonymous_variant LOW 795A>G Gln265Gln
M0209139 NNOANBKH_00029 26540 3 Gut 0.19 protein_coding synonymous_variant LOW 606A>C Ser202Ser
M0209140 NNOANBKH_00029 26569 3 Gut 0.19 protein_coding missense_variant MODERATE 577G>A Asp193Asn
M0209141 NNOANBKH_00029 26645 3 Gut 0.19 protein_coding synonymous_variant LOW 501A>T Val167Val
M0209142 NNOANBKH_00030 27391 3 Gut 0.19 protein_coding synonymous_variant LOW 399T>C Ser133Ser
M0209143 NNOANBKH_00031 27825 3 Gut 0.19 protein_coding synonymous_variant LOW 1167C>A Gly389Gly
M0209144 NNOANBKH_00031 28037 3 Gut 0.19 protein_coding missense_variant MODERATE 955G>A Ala319Thr
M0209145 NNOANBKH_00031 28287 3 Gut 0.19 protein_coding synonymous_variant LOW 705T>C Arg235Arg
M0209146 NNOANBKH_00033 31345 3 Gut 0.19 protein_coding synonymous_variant LOW 1269C>A Thr423Thr
M0209147 NNOANBKH_00033 31825 3 Gut 0.19 protein_coding synonymous_variant LOW 789T>C Pro263Pro
M0209148 NNOANBKH_00033 31870 3 Gut 0.19 protein_coding synonymous_variant LOW 744G>A Gln248Gln
M0209149 NNOANBKH_00033 31945 3 Gut 0.19 protein_coding synonymous_variant LOW 669C>T Ala223Ala
M0209150 NNOANBKH_00033 32059 3 Gut 0.19 protein_coding synonymous_variant LOW 555C>A Val185Val
M0209151 NNOANBKH_00033 32076 3 Gut 0.19 protein_coding missense_variant MODERATE 538G>A Asp180Asn
M0209152 NNOANBKH_00031 32814 3 Gut 0.19 protein_coding upstream_gene_variant MODIFIER -3823A>G None
M0209153 NNOANBKH_00034 32996 3 Gut 0.19 protein_coding missense_variant MODERATE 539A>C Glu180Ala
M0209154 NNOANBKH_00034 33518 3 Gut 0.19 protein_coding missense_variant MODERATE 17A>G Gln6Arg
M0209155 NNOANBKH_00036 34099 3 Gut 0.19 protein_coding synonymous_variant LOW 249A>C Gly83Gly
M0209156 NNOANBKH_00037 34776 3 Gut 0.19 protein_coding missense_variant MODERATE 149A>G His50Arg
M0209157 NNOANBKH_00038 35155 3 Gut 0.19 protein_coding synonymous_variant LOW 480G>A Leu160Leu
M0209158 NNOANBKH_00039 36153 3 Gut 0.19 protein_coding synonymous_variant LOW 816G>C Val272Val
M0209159 NNOANBKH_00039 36173 3 Gut 0.19 protein_coding synonymous_variant LOW 796A>C Arg266Arg
M0209160 NNOANBKH_00039 36240 3 Gut 0.19 protein_coding synonymous_variant LOW 729C>T Val243Val
M0209161 NNOANBKH_00039 36246 3 Gut 0.19 protein_coding synonymous_variant LOW 723G>A Gly241Gly
M0209162 NNOANBKH_00039 36258 3 Gut 0.19 protein_coding synonymous_variant LOW 711C>G Gly237Gly
M0209163 NNOANBKH_00039 36282 3 Gut 0.19 protein_coding synonymous_variant LOW 687T>C Arg229Arg
M0209164 NNOANBKH_00039 36310 3 Gut 0.19 protein_coding missense_variant MODERATE 659A>C Glu220Ala
M0209165 NNOANBKH_00039 36315 3 Gut 0.19 protein_coding synonymous_variant LOW 654T>C Asp218Asp
M0209166 NNOANBKH_00039 36318 3 Gut 0.19 protein_coding synonymous_variant LOW 651T>C Ile217Ile
M0209167 NNOANBKH_00039 36324 3 Gut 0.19 protein_coding synonymous_variant LOW 645C>T Ala215Ala
M0209168 NNOANBKH_00039 36364 3 Gut 0.19 protein_coding missense_variant MODERATE 605C>A Pro202Gln
M0209169 NNOANBKH_00039 36371 3 Gut 0.19 protein_coding missense_variant MODERATE 598G>A Ala200Thr
M0209170 NNOANBKH_00039 36372 3 Gut 0.19 protein_coding synonymous_variant LOW 597A>T Ala199Ala
M0209171 NNOANBKH_00039 36378 3 Gut 0.19 protein_coding synonymous_variant LOW 591C>A Thr197Thr
M0209172 NNOANBKH_00039 36411 3 Gut 0.19 protein_coding synonymous_variant LOW 558A>G Gln186Gln
M0209173 NNOANBKH_00039 36431 3 Gut 0.19 protein_coding missense_variant MODERATE 538C>T Pro180Ser
M0209174 NNOANBKH_00039 36444 3 Gut 0.19 protein_coding synonymous_variant LOW 525A>T Pro175Pro
M0209175 NNOANBKH_00039 36459 3 Gut 0.19 protein_coding synonymous_variant LOW 510T>G Thr170Thr
M0209176 NNOANBKH_00039 36461 3 Gut 0.19 protein_coding missense_variant MODERATE 508A>G Thr170Ala
M0209177 NNOANBKH_00039 36522 3 Gut 0.19 protein_coding synonymous_variant LOW 447T>C Asn149Asn
M0209178 NNOANBKH_00039 36573 3 Gut 0.19 protein_coding synonymous_variant LOW 396T>G Thr132Thr
M0209179 NNOANBKH_00039 36591 3 Gut 0.19 protein_coding synonymous_variant LOW 378C>T Pro126Pro
M0209180 NNOANBKH_00039 36885 3 Gut 0.19 protein_coding synonymous_variant LOW 84C>T Ile28Ile
M0209181 NNOANBKH_00040 37350 3 Gut 0.19 protein_coding synonymous_variant LOW 597G>A Thr199Thr
M0209182 NNOANBKH_00040 37539 3 Gut 0.19 protein_coding synonymous_variant LOW 408G>T Thr136Thr
M0209183 NNOANBKH_00040 37709 3 Gut 0.19 protein_coding missense_variant MODERATE 238A>G Ser80Gly
M0209184 NNOANBKH_00041 38152 3 Gut 0.19 protein_coding synonymous_variant LOW 501G>A Gln167Gln
M0209185 NNOANBKH_00043 39394 3 Gut 0.19 protein_coding synonymous_variant LOW 3699G>A Leu1233Leu
M0209186 NNOANBKH_00043 40189 3 Gut 0.19 protein_coding synonymous_variant LOW 2904T>C Ala968Ala
M0209187 NNOANBKH_00043 40772 3 Gut 0.19 protein_coding missense_variant MODERATE 2321T>G Val774Gly
M0209188 NNOANBKH_00043 40792 3 Gut 0.19 protein_coding synonymous_variant LOW 2301G>T Leu767Leu
M0209189 NNOANBKH_00043 40962 3 Gut 0.19 protein_coding missense_variant MODERATE 2131G>A Ala711Thr
M0209190 NNOANBKH_00043 41203 3 Gut 0.19 protein_coding synonymous_variant LOW 1890C>T Ala630Ala
M0209191 NNOANBKH_00043 41269 3 Gut 0.19 protein_coding synonymous_variant LOW 1824T>C Val608Val
M0209192 NNOANBKH_00043 41352 3 Gut 0.19 protein_coding missense_variant MODERATE 1741G>A Glu581Lys
M0209193 NNOANBKH_00043 41521 3 Gut 0.19 protein_coding synonymous_variant LOW 1572G>A Gln524Gln
M0209194 NNOANBKH_00043 42543 3 Gut 0.19 protein_coding missense_variant MODERATE 550A>G Arg184Gly
M0209195 NNOANBKH_00043 42601 3 Gut 0.19 protein_coding synonymous_variant LOW 492T>A Ala164Ala
M0209196 NNOANBKH_00043 42712 3 Gut 0.19 protein_coding synonymous_variant LOW 381G>A Arg127Arg
M0209197 NNOANBKH_00044 43311 3 Gut 0.19 protein_coding synonymous_variant LOW 136T>C Leu46Leu
M0209198 NNOANBKH_00046 44854 3 Gut 0.19 protein_coding synonymous_variant LOW 558G>A Gln186Gln
M0209199 NNOANBKH_00047 45585 3 Gut 0.19 protein_coding synonymous_variant LOW 282C>A Arg94Arg
M0209200 NNOANBKH_00048 45999 3 Gut 0.19 protein_coding missense_variant MODERATE 1174G>A Ala392Thr
M0209201 NNOANBKH_00048 46165 3 Gut 0.19 protein_coding synonymous_variant LOW 1008A>T Val336Val
M0209202 NNOANBKH_00048 46554 3 Gut 0.19 protein_coding synonymous_variant LOW 619T>C Leu207Leu
M0209203 NNOANBKH_00048 46988 3 Gut 0.19 protein_coding missense_variant MODERATE 185A>C Glu62Ala
M0209204 NNOANBKH_00048 47026 3 Gut 0.19 protein_coding synonymous_variant LOW 147C>A Ala49Ala
M0209205 NNOANBKH_00049 47397 3 Gut 0.19 protein_coding synonymous_variant LOW 699C>A Ala233Ala
M0209206 NNOANBKH_00044 48295 3 Gut 0.19 protein_coding upstream_gene_variant MODIFIER -4849C>A None
M0209207 NNOANBKH_00044 48296 3 Gut 0.19 protein_coding upstream_gene_variant MODIFIER -4850C>A None
M0209208 NNOANBKH_00044 48361 3 Gut 0.19 protein_coding upstream_gene_variant MODIFIER -4915A>G None
M0209209 NNOANBKH_00045 48549 3 Gut 0.19 protein_coding upstream_gene_variant MODIFIER -3958T>C None
M0209210 NNOANBKH_00051 50500 3 Gut 0.19 protein_coding missense_variant MODERATE 74G>T Arg25Leu
M0209211 NNOANBKH_00053 51440 3 Gut 0.19 protein_coding synonymous_variant LOW 216A>G Gln72Gln
M0209212 NNOANBKH_00057 55241 3 Gut 0.19 protein_coding synonymous_variant LOW 927A>G Pro309Pro
M0209213 NNOANBKH_00058 56530 3 Gut 0.19 protein_coding synonymous_variant LOW 1278C>T Thr426Thr
M0209214 NNOANBKH_00058 57516 3 Gut 0.19 protein_coding missense_variant MODERATE 292C>G Gln98Glu
M0209215 NNOANBKH_00058 57728 3 Gut 0.19 protein_coding missense_variant MODERATE 80T>C Ile27Thr
M0209216 NNOANBKH_00059 57926 3 Gut 0.19 protein_coding missense_variant MODERATE 351A>C Lys117Asn
M0209217 NNOANBKH_00059 57932 3 Gut 0.19 protein_coding synonymous_variant LOW 345A>G Val115Val
M0209218 NNOANBKH_00060 58708 3 Gut 0.19 protein_coding missense_variant MODERATE 643A>G Thr215Ala
M0209219 NNOANBKH_00057 59923 3 Gut 0.19 protein_coding upstream_gene_variant MODIFIER -3756G>T None
M0209220 NNOANBKH_00057 59969 3 Gut 0.19 protein_coding upstream_gene_variant MODIFIER -3802C>G None
M0209221 NNOANBKH_00057 59991 3 Gut 0.19 protein_coding upstream_gene_variant MODIFIER -3824A>G None
M0209222 NNOANBKH_00057 60005 3 Gut 0.19 protein_coding upstream_gene_variant MODIFIER -3838T>C None
M0209223 NNOANBKH_00057 60011 3 Gut 0.19 protein_coding upstream_gene_variant MODIFIER -3844C>T None
M0209224 NNOANBKH_00063 61343 3 Gut 0.19 protein_coding synonymous_variant LOW 702A>C Ala234Ala
M0209225 NNOANBKH_00063 61565 3 Gut 0.19 protein_coding synonymous_variant LOW 480C>G Val160Val
M0209226 NNOANBKH_00063 61886 3 Gut 0.19 protein_coding synonymous_variant LOW 159T>A Gly53Gly
M0209227 NNOANBKH_00059 62872 3 Gut 0.19 protein_coding upstream_gene_variant MODIFIER -4596G>T None
M0209228 NNOANBKH_00065 62975 3 Gut 0.19 protein_coding missense_variant MODERATE 646A>T Ser216Cys
M0209229 NNOANBKH_00061 64577 3 Gut 0.19 protein_coding upstream_gene_variant MODIFIER -4666A>T None
M0209230 NNOANBKH_00061 64579 3 Gut 0.19 protein_coding upstream_gene_variant MODIFIER -4668A>G None
M0209231 NNOANBKH_00067 65872 3 Gut 0.19 protein_coding synonymous_variant LOW 768C>G Arg256Arg
M0209232 NNOANBKH_00067 65976 3 Gut 0.19 protein_coding stop_lost&splice_region_variant HIGH 872G>T Ter291Leuext*?
M0209233 NNOANBKH_00063 66098 3 Gut 0.19 protein_coding upstream_gene_variant MODIFIER -4054T>C None
M0209234 NNOANBKH_00063 66099 3 Gut 0.19 protein_coding upstream_gene_variant MODIFIER -4055A>G None
M0209235 NNOANBKH_00063 66101 3 Gut 0.19 protein_coding upstream_gene_variant MODIFIER -4057T>A None
M0209236 NNOANBKH_00063 66144 3 Gut 0.19 protein_coding upstream_gene_variant MODIFIER -4100A>C None
M0209237 NNOANBKH_00063 66184 3 Gut 0.19 protein_coding upstream_gene_variant MODIFIER -4140T>C None
M0209238 NNOANBKH_00063 66255 3 Gut 0.19 protein_coding upstream_gene_variant MODIFIER -4211A>G None
M0209239 NNOANBKH_00063 66286 3 Gut 0.19 protein_coding upstream_gene_variant MODIFIER -4242A>G None
M0209240 NNOANBKH_00063 66303 3 Gut 0.19 protein_coding upstream_gene_variant MODIFIER -4259C>T None
M0209241 NNOANBKH_00063 66306 3 Gut 0.19 protein_coding upstream_gene_variant MODIFIER -4262T>C None
M0209242 NNOANBKH_00063 66311 3 Gut 0.19 protein_coding upstream_gene_variant MODIFIER -4267C>T None
M0209243 NNOANBKH_00063 66316 3 Gut 0.19 protein_coding upstream_gene_variant MODIFIER -4272T>C None
M0209244 NNOANBKH_00063 66337 3 Gut 0.19 protein_coding upstream_gene_variant MODIFIER -4293A>T None
M0209245 NNOANBKH_00063 66338 3 Gut 0.19 protein_coding upstream_gene_variant MODIFIER -4294C>T None
M0209246 NNOANBKH_00063 66395 3 Gut 0.19 protein_coding upstream_gene_variant MODIFIER -4351C>T None
M0209247 NNOANBKH_00063 66444 3 Gut 0.19 protein_coding upstream_gene_variant MODIFIER -4400G>A None
M0209248 NNOANBKH_00064 67491 3 Gut 0.19 protein_coding upstream_gene_variant MODIFIER -4800G>A None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism
NNOANBKH_00002 ARO:3003479 100 1.46e-152 1 207 1.0000 0.9952 tetracycline antibiotic major facilitator superfamily (MFS) antibiotic efflux pump antibiotic target alteration
NNOANBKH_00003 ARO:3000166 99 3.57e-282 1 401 1.0000 1.0000 tetracycline antibiotic major facilitator superfamily (MFS) antibiotic efflux pump antibiotic efflux
NNOANBKH_00012 ARO:3000412 100 4.11e-186 1 271 1.0000 1.0000 sulfonamide antibiotic sulfonamide resistant sul antibiotic target replacement






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
NNOANBKH_00052 SPE00673.1|GH23 100 1.33e-115 1 161 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
NNOANBKH_00003 2.A.1.2.68 99.5 3.2e-220 1 401 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.1 The Major Facilitator Superfamily (MFS)
NNOANBKH_00014 3.A.7.10.1 79.6 0 1 724 0.9439 7.5417 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.7 The Type IV (Conjugal DNA-Protein Transfer or VirB) Secretory Pathway (IVSP) Family
NNOANBKH_00016 3.A.7.10.1 76.1 1.1e-189 1 401 0.9093 4.1771 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.7 The Type IV (Conjugal DNA-Protein Transfer or VirB) Secretory Pathway (IVSP) Family
NNOANBKH_00025 1.E.53.1.10 100 2e-18 8 50 0.8600 1.0000 1 Channels/Pores 1.E Holins 1.E.53 The Toxic Hok/Gef Protein (Hok/Gef) Family
NNOANBKH_00040 3.A.7.10.1 74.9 1.5e-138 1 324 1.0000 3.4063 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.7 The Type IV (Conjugal DNA-Protein Transfer or VirB) Secretory Pathway (IVSP) Family
NNOANBKH_00042 3.A.7.10.1 73.3 1.9e-40 1 116 1.0000 1.1979 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.7 The Type IV (Conjugal DNA-Protein Transfer or VirB) Secretory Pathway (IVSP) Family
NNOANBKH_00045 3.A.7.10.1 77.8 1.7e-175 1 379 0.9921 3.9479 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.7 The Type IV (Conjugal DNA-Protein Transfer or VirB) Secretory Pathway (IVSP) Family
NNOANBKH_00046 3.A.7.10.1 77.9 6.6e-124 1 271 0.9748 2.8021 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.7 The Type IV (Conjugal DNA-Protein Transfer or VirB) Secretory Pathway (IVSP) Family