Annotation Categories of the Plasmid Cluster
Summary of the plasmid cluster
Basic Information about the Plasmid Cluster
Cluster Information |
Plasmid Cluster ID |
C1422 |
Reference Plasmid |
NZ_OY725717.1 |
Reference Plasmid Size |
899693 |
Reference Plasmid GC Content |
0.60 |
Reference Plasmid Mobility Type |
non-mobilizable |
Mutation sites in the plasmid cluster
The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..
mutid |
gname |
pos |
count |
tissue |
frequnt |
biotype |
consequence |
impact |
nucchange |
aachange |
M0209633 |
PKENNHKI_00660 |
758838 |
15 |
Gut |
0.18 |
protein_coding |
synonymous_variant |
LOW |
984T>C |
Phe328Phe |
M0209634 |
PKENNHKI_00660 |
758931 |
12 |
Gut |
0.15 |
protein_coding |
synonymous_variant |
LOW |
1077C>T |
Ser359Ser |
M0209635 |
PKENNHKI_00660 |
758958 |
17 |
Gut |
0.21 |
protein_coding |
synonymous_variant |
LOW |
1104A>G |
Val368Val |
M0209636 |
PKENNHKI_00660 |
759072 |
15 |
Gut |
0.18 |
protein_coding |
synonymous_variant |
LOW |
1218A>G |
Leu406Leu |
M0209637 |
PKENNHKI_00660 |
759135 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
1281G>A |
Glu427Glu |
M0209638 |
PKENNHKI_00660 |
759169 |
11 |
Gut |
0.13 |
protein_coding |
missense_variant |
MODERATE |
1315A>G |
Asn439Asp |
M0209639 |
PKENNHKI_00660 |
759177 |
7 |
Gut |
0.09 |
protein_coding |
synonymous_variant |
LOW |
1323C>T |
Ala441Ala |
M0209640 |
PKENNHKI_00660 |
759180 |
7 |
Gut |
0.09 |
protein_coding |
synonymous_variant |
LOW |
1326T>C |
Ala442Ala |
M0209641 |
PKENNHKI_00660 |
759181 |
6 |
Gut |
0.07 |
protein_coding |
missense_variant |
MODERATE |
1327G>A |
Ala443Thr |
M0209642 |
PKENNHKI_00660 |
759193 |
9 |
Gut |
0.11 |
protein_coding |
missense_variant |
MODERATE |
1339G>A |
Asp447Asn |
M0209643 |
PKENNHKI_00660 |
759220 |
5 |
Gut |
0.06 |
protein_coding |
missense_variant |
MODERATE |
1366G>A |
Ala456Thr |
M0209644 |
PKENNHKI_00660 |
759223 |
4 |
Gut |
0.05 |
protein_coding |
missense_variant |
MODERATE |
1369A>G |
Thr457Ala |
M0209645 |
PKENNHKI_00660 |
759238 |
9 |
Gut |
0.11 |
protein_coding |
missense_variant |
MODERATE |
1384A>G |
Thr462Ala |
M0209646 |
PKENNHKI_00660 |
759246 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
1392C>T |
Ala464Ala |
M0209647 |
PKENNHKI_00660 |
759249 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
1395T>C |
Ala465Ala |
M0209648 |
PKENNHKI_00660 |
759258 |
10 |
Gut |
0.12 |
protein_coding |
missense_variant |
MODERATE |
1404A>C |
Glu468Asp |
M0209649 |
PKENNHKI_00660 |
759288 |
12 |
Gut |
0.15 |
protein_coding |
synonymous_variant |
LOW |
1434T>C |
Pro478Pro |
M0209650 |
PKENNHKI_00660 |
759351 |
12 |
Gut |
0.15 |
protein_coding |
synonymous_variant |
LOW |
1497T>C |
Gly499Gly |
M0209651 |
PKENNHKI_00660 |
759441 |
11 |
Gut |
0.13 |
protein_coding |
synonymous_variant |
LOW |
1587T>C |
Gly529Gly |
M0209652 |
PKENNHKI_00660 |
759564 |
6 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
1710T>C |
Gly570Gly |
M0209653 |
PKENNHKI_00660 |
759597 |
12 |
Gut |
0.15 |
protein_coding |
synonymous_variant |
LOW |
1743C>T |
Ala581Ala |
M0209654 |
PKENNHKI_00660 |
759606 |
12 |
Gut |
0.15 |
protein_coding |
synonymous_variant |
LOW |
1752T>C |
Ile584Ile |
M0209655 |
PKENNHKI_00659 |
759634 |
3 |
Gut |
0.04 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2064A>C |
None |
M0209656 |
PKENNHKI_00659 |
759688 |
5 |
Gut |
0.06 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2118A>T |
None |
M0209657 |
PKENNHKI_00661 |
759739 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
30C>T |
Gly10Gly |
M0209658 |
PKENNHKI_00661 |
759745 |
11 |
Gut |
0.13 |
protein_coding |
synonymous_variant |
LOW |
36C>G |
Val12Val |
M0209659 |
PKENNHKI_00661 |
759763 |
7 |
Gut |
0.09 |
protein_coding |
synonymous_variant |
LOW |
54T>C |
Ala18Ala |
M0209660 |
PKENNHKI_00661 |
759790 |
5 |
Gut |
0.06 |
protein_coding |
synonymous_variant |
LOW |
81T>C |
Arg27Arg |
M0209661 |
PKENNHKI_00661 |
759835 |
8 |
Gut |
0.10 |
protein_coding |
synonymous_variant |
LOW |
126C>T |
Ala42Ala |
M0209662 |
PKENNHKI_00661 |
759859 |
10 |
Gut |
0.12 |
protein_coding |
synonymous_variant |
LOW |
150T>C |
Pro50Pro |
M0209663 |
PKENNHKI_00661 |
759868 |
7 |
Gut |
0.09 |
protein_coding |
synonymous_variant |
LOW |
159C>T |
Asp53Asp |
M0209664 |
PKENNHKI_00661 |
759880 |
8 |
Gut |
0.10 |
protein_coding |
synonymous_variant |
LOW |
171A>G |
Lys57Lys |
M0209665 |
PKENNHKI_00661 |
759883 |
8 |
Gut |
0.10 |
protein_coding |
synonymous_variant |
LOW |
174T>C |
Tyr58Tyr |
M0209666 |
PKENNHKI_00661 |
759898 |
10 |
Gut |
0.12 |
protein_coding |
synonymous_variant |
LOW |
189T>C |
Asp63Asp |
M0209667 |
PKENNHKI_00661 |
759899 |
9 |
Gut |
0.11 |
protein_coding |
synonymous_variant |
LOW |
190T>C |
Leu64Leu |
M0209668 |
PKENNHKI_00661 |
759913 |
9 |
Gut |
0.11 |
protein_coding |
synonymous_variant |
LOW |
204T>C |
Phe68Phe |
M0209669 |
PKENNHKI_00661 |
759919 |
8 |
Gut |
0.10 |
protein_coding |
synonymous_variant |
LOW |
210T>C |
Ile70Ile |
M0209670 |
PKENNHKI_00661 |
759925 |
7 |
Gut |
0.09 |
protein_coding |
synonymous_variant |
LOW |
216C>T |
Gly72Gly |
M0209671 |
PKENNHKI_00661 |
759928 |
5 |
Gut |
0.06 |
protein_coding |
synonymous_variant |
LOW |
219T>C |
Ile73Ile |
M0209672 |
PKENNHKI_00661 |
759963 |
8 |
Gut |
0.10 |
protein_coding |
missense_variant |
MODERATE |
254G>A |
Ser85Asn |
M0209673 |
PKENNHKI_00661 |
759964 |
6 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
255T>C |
Ser85Ser |
M0209674 |
PKENNHKI_00661 |
759970 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
261C>T |
Thr87Thr |
M0209675 |
PKENNHKI_00661 |
759979 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
270T>C |
Ile90Ile |
M0209676 |
PKENNHKI_00661 |
759997 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
288T>C |
Ala96Ala |
M0209677 |
PKENNHKI_00661 |
760033 |
9 |
Gut |
0.11 |
protein_coding |
synonymous_variant |
LOW |
324T>C |
Ala108Ala |
M0209678 |
PKENNHKI_00661 |
760066 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
357C>T |
Phe119Phe |
M0209679 |
PKENNHKI_00661 |
760091 |
6 |
Gut |
0.07 |
protein_coding |
missense_variant |
MODERATE |
382A>G |
Asn128Asp |
M0209680 |
PKENNHKI_00661 |
760105 |
9 |
Gut |
0.11 |
protein_coding |
synonymous_variant |
LOW |
396T>C |
Gly132Gly |
M0209681 |
PKENNHKI_00661 |
760118 |
10 |
Gut |
0.12 |
protein_coding |
missense_variant |
MODERATE |
409G>A |
Ala137Thr |
M0209682 |
PKENNHKI_00661 |
760135 |
10 |
Gut |
0.12 |
protein_coding |
synonymous_variant |
LOW |
426C>T |
Phe142Phe |
M0209683 |
PKENNHKI_00661 |
760261 |
7 |
Gut |
0.09 |
protein_coding |
synonymous_variant |
LOW |
552C>T |
Tyr184Tyr |
M0209684 |
PKENNHKI_00661 |
760318 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
609T>C |
Ala203Ala |
M0209685 |
PKENNHKI_00661 |
760396 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
687C>T |
Asp229Asp |
M0209686 |
PKENNHKI_00661 |
760765 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
1056C>T |
Ile352Ile |
M0209687 |
PKENNHKI_00661 |
760783 |
5 |
Gut |
0.06 |
protein_coding |
synonymous_variant |
LOW |
1074C>G |
Leu358Leu |
M0209688 |
PKENNHKI_00661 |
760879 |
6 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
1170T>C |
Asp390Asp |
M0209689 |
PKENNHKI_00661 |
760921 |
8 |
Gut |
0.10 |
protein_coding |
synonymous_variant |
LOW |
1212A>G |
Gln404Gln |
M0209690 |
PKENNHKI_00661 |
760972 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
1263C>T |
Gly421Gly |
M0209691 |
PKENNHKI_00658 |
755577 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
1023G>A |
Glu341Glu |
M0209692 |
PKENNHKI_00658 |
755811 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
1257G>A |
Leu419Leu |
M0209693 |
PKENNHKI_00658 |
755964 |
8 |
Gut |
0.10 |
protein_coding |
synonymous_variant |
LOW |
1410C>T |
Thr470Thr |
M0209694 |
PKENNHKI_00658 |
756307 |
11 |
Gut |
0.13 |
protein_coding |
missense_variant |
MODERATE |
1753A>G |
Lys585Glu |
M0209695 |
PKENNHKI_00656 |
756404 |
7 |
Gut |
0.09 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-3809G>A |
None |
M0209696 |
PKENNHKI_00659 |
756650 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
921A>G |
Leu307Leu |
M0209697 |
PKENNHKI_00659 |
756653 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
918C>T |
Gly306Gly |
M0209698 |
PKENNHKI_00659 |
756656 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
915G>A |
Ala305Ala |
M0209699 |
PKENNHKI_00659 |
756743 |
5 |
Gut |
0.06 |
protein_coding |
synonymous_variant |
LOW |
828T>C |
Leu276Leu |
M0209700 |
PKENNHKI_00659 |
756749 |
5 |
Gut |
0.06 |
protein_coding |
synonymous_variant |
LOW |
822C>T |
Asp274Asp |
M0209701 |
PKENNHKI_00659 |
756752 |
5 |
Gut |
0.06 |
protein_coding |
synonymous_variant |
LOW |
819T>C |
Asp273Asp |
M0209702 |
PKENNHKI_00659 |
756755 |
5 |
Gut |
0.06 |
protein_coding |
synonymous_variant |
LOW |
816T>C |
Phe272Phe |
M0209703 |
PKENNHKI_00659 |
756773 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
798T>C |
Asp266Asp |
M0209704 |
PKENNHKI_00659 |
756776 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
795T>C |
Asp265Asp |
M0209705 |
PKENNHKI_00659 |
756788 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
783G>C |
Leu261Leu |
M0209706 |
PKENNHKI_00659 |
756791 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
780T>G |
Gly260Gly |
M0209707 |
PKENNHKI_00659 |
756794 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
777G>A |
Lys259Lys |
M0209708 |
PKENNHKI_00659 |
756887 |
6 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
684T>G |
Ala228Ala |
M0209709 |
PKENNHKI_00659 |
756959 |
6 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
612G>A |
Ala204Ala |
M0209710 |
PKENNHKI_00659 |
756965 |
5 |
Gut |
0.06 |
protein_coding |
synonymous_variant |
LOW |
606A>T |
Arg202Arg |
M0209711 |
PKENNHKI_00659 |
756971 |
5 |
Gut |
0.06 |
protein_coding |
synonymous_variant |
LOW |
600C>T |
Gly200Gly |
M0209712 |
PKENNHKI_00659 |
756980 |
6 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
591A>T |
Arg197Arg |
M0209713 |
PKENNHKI_00659 |
757013 |
6 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
558G>T |
Ser186Ser |
M0209714 |
PKENNHKI_00659 |
757016 |
5 |
Gut |
0.06 |
protein_coding |
synonymous_variant |
LOW |
555T>C |
Val185Val |
M0209715 |
PKENNHKI_00659 |
757041 |
4 |
Gut |
0.05 |
protein_coding |
missense_variant |
MODERATE |
530A>G |
His177Arg |
M0209716 |
PKENNHKI_00659 |
757043 |
5 |
Gut |
0.06 |
protein_coding |
synonymous_variant |
LOW |
528C>T |
Asn176Asn |
M0209717 |
PKENNHKI_00659 |
757085 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
486T>C |
Asp162Asp |
M0209718 |
PKENNHKI_00659 |
757100 |
6 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
471C>T |
Ser157Ser |
M0209719 |
PKENNHKI_00659 |
757121 |
7 |
Gut |
0.09 |
protein_coding |
synonymous_variant |
LOW |
450A>G |
Pro150Pro |
M0209720 |
PKENNHKI_00659 |
757124 |
6 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
447A>G |
Thr149Thr |
M0209721 |
PKENNHKI_00659 |
757187 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
384T>C |
Arg128Arg |
M0209722 |
PKENNHKI_00659 |
757199 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
372C>T |
Ile124Ile |
M0209723 |
PKENNHKI_00659 |
757208 |
6 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
363T>C |
Asp121Asp |
M0209724 |
PKENNHKI_00659 |
757211 |
6 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
360T>C |
Val120Val |
M0209725 |
PKENNHKI_00659 |
757214 |
6 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
357T>C |
Pro119Pro |
M0209726 |
PKENNHKI_00659 |
757217 |
6 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
354G>T |
Leu118Leu |
M0209727 |
PKENNHKI_00659 |
757232 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
339C>T |
Arg113Arg |
M0209728 |
PKENNHKI_00659 |
757241 |
7 |
Gut |
0.09 |
protein_coding |
missense_variant |
MODERATE |
330T>A |
Asp110Glu |
M0209729 |
PKENNHKI_00659 |
757265 |
7 |
Gut |
0.09 |
protein_coding |
synonymous_variant |
LOW |
306T>G |
Ala102Ala |
M0209730 |
PKENNHKI_00659 |
757268 |
6 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
303C>G |
Arg101Arg |
M0209731 |
PKENNHKI_00659 |
757277 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
294C>T |
Ile98Ile |
M0209732 |
PKENNHKI_00659 |
757289 |
5 |
Gut |
0.06 |
protein_coding |
synonymous_variant |
LOW |
282T>G |
Ala94Ala |
M0209733 |
PKENNHKI_00659 |
757305 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
266A>C |
Glu89Ala |
M0209734 |
PKENNHKI_00659 |
757358 |
6 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
213T>C |
Phe71Phe |
M0209735 |
PKENNHKI_00659 |
757363 |
5 |
Gut |
0.06 |
protein_coding |
missense_variant |
MODERATE |
208A>C |
Met70Leu |
M0209736 |
PKENNHKI_00659 |
757418 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
153C>G |
Thr51Thr |
M0209737 |
PKENNHKI_00659 |
757420 |
7 |
Gut |
0.09 |
protein_coding |
missense_variant |
MODERATE |
151A>G |
Thr51Ala |
M0209738 |
PKENNHKI_00659 |
757421 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
150A>G |
Arg50Arg |
M0209739 |
PKENNHKI_00659 |
757424 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
147T>C |
Phe49Phe |
M0209740 |
PKENNHKI_00659 |
757430 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
141C>T |
Leu47Leu |
M0209741 |
PKENNHKI_00659 |
757436 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
135G>A |
Glu45Glu |
M0209742 |
PKENNHKI_00659 |
757445 |
5 |
Gut |
0.06 |
protein_coding |
synonymous_variant |
LOW |
126G>T |
Ala42Ala |
M0209743 |
PKENNHKI_00659 |
757463 |
8 |
Gut |
0.10 |
protein_coding |
synonymous_variant |
LOW |
108G>A |
Thr36Thr |
M0209744 |
PKENNHKI_00659 |
757484 |
9 |
Gut |
0.11 |
protein_coding |
synonymous_variant |
LOW |
87T>C |
Pro29Pro |
M0209745 |
PKENNHKI_00659 |
757499 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
72C>T |
Arg24Arg |
M0209746 |
PKENNHKI_00659 |
757505 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
66G>T |
Val22Val |
M0209747 |
PKENNHKI_00659 |
757534 |
5 |
Gut |
0.06 |
protein_coding |
missense_variant |
MODERATE |
37G>A |
Val13Ile |
M0209748 |
PKENNHKI_00659 |
757535 |
5 |
Gut |
0.06 |
protein_coding |
synonymous_variant |
LOW |
36A>G |
Ala12Ala |
M0209749 |
PKENNHKI_00656 |
757581 |
4 |
Gut |
0.05 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4986T>C |
None |
M0209750 |
PKENNHKI_00659 |
757609 |
3 |
Gut |
0.04 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-39A>G |
None |
M0209751 |
PKENNHKI_00659 |
757616 |
6 |
Gut |
0.07 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-46A>G |
None |
M0209752 |
PKENNHKI_00659 |
757639 |
5 |
Gut |
0.06 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-69G>A |
None |
M0209753 |
PKENNHKI_00659 |
757640 |
8 |
Gut |
0.10 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-70T>C |
None |
M0209754 |
PKENNHKI_00659 |
757646 |
5 |
Gut |
0.06 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-76G>A |
None |
M0209755 |
PKENNHKI_00659 |
757653 |
7 |
Gut |
0.09 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-83C>T |
None |
M0209756 |
PKENNHKI_00659 |
757661 |
7 |
Gut |
0.09 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-91A>G |
None |
M0209757 |
PKENNHKI_00659 |
757678 |
7 |
Gut |
0.09 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-108A>G |
None |
M0209758 |
PKENNHKI_00659 |
757768 |
12 |
Gut |
0.15 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-198G>T |
None |
M0209759 |
PKENNHKI_00659 |
757769 |
12 |
Gut |
0.15 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-199G>C |
None |
M0209760 |
PKENNHKI_00659 |
757840 |
11 |
Gut |
0.13 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-270G>A |
None |
M0209761 |
PKENNHKI_00660 |
757965 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
111C>T |
Ile37Ile |
M0209762 |
PKENNHKI_00660 |
757971 |
6 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
117T>C |
Leu39Leu |
M0209763 |
PKENNHKI_00660 |
757992 |
6 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
138G>C |
Leu46Leu |
M0209764 |
PKENNHKI_00660 |
757995 |
5 |
Gut |
0.06 |
protein_coding |
synonymous_variant |
LOW |
141C>T |
Ile47Ile |
M0209765 |
PKENNHKI_00660 |
758001 |
12 |
Gut |
0.15 |
protein_coding |
synonymous_variant |
LOW |
147G>C |
Thr49Thr |
M0209766 |
PKENNHKI_00660 |
758061 |
11 |
Gut |
0.13 |
protein_coding |
synonymous_variant |
LOW |
207C>G |
Leu69Leu |
M0209767 |
PKENNHKI_00660 |
758127 |
10 |
Gut |
0.12 |
protein_coding |
synonymous_variant |
LOW |
273A>T |
Ala91Ala |
M0209768 |
PKENNHKI_00660 |
758157 |
11 |
Gut |
0.13 |
protein_coding |
synonymous_variant |
LOW |
303A>G |
Lys101Lys |
M0209769 |
PKENNHKI_00660 |
758172 |
11 |
Gut |
0.13 |
protein_coding |
synonymous_variant |
LOW |
318T>C |
Gly106Gly |
M0209770 |
PKENNHKI_00660 |
758205 |
10 |
Gut |
0.12 |
protein_coding |
synonymous_variant |
LOW |
351T>G |
Leu117Leu |
M0209771 |
PKENNHKI_00660 |
758206 |
10 |
Gut |
0.12 |
protein_coding |
synonymous_variant |
LOW |
352T>C |
Leu118Leu |
M0209772 |
PKENNHKI_00660 |
758214 |
9 |
Gut |
0.11 |
protein_coding |
synonymous_variant |
LOW |
360C>T |
Ala120Ala |
M0209773 |
PKENNHKI_00660 |
758280 |
6 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
426T>C |
Gly142Gly |
M0209774 |
PKENNHKI_00660 |
758331 |
10 |
Gut |
0.12 |
protein_coding |
synonymous_variant |
LOW |
477T>C |
Val159Val |
M0209775 |
PKENNHKI_00660 |
758334 |
6 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
480T>C |
Tyr160Tyr |
M0209776 |
PKENNHKI_00660 |
758337 |
7 |
Gut |
0.09 |
protein_coding |
synonymous_variant |
LOW |
483G>A |
Lys161Lys |
M0209777 |
PKENNHKI_00660 |
758502 |
6 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
648C>T |
Leu216Leu |
M0209778 |
PKENNHKI_00660 |
758508 |
6 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
654G>A |
Lys218Lys |
M0209779 |
PKENNHKI_00660 |
758526 |
7 |
Gut |
0.09 |
protein_coding |
synonymous_variant |
LOW |
672T>C |
Phe224Phe |
M0209780 |
PKENNHKI_00660 |
758595 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
741C>T |
Gly247Gly |
M0209781 |
PKENNHKI_00660 |
758607 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
753C>T |
Pro251Pro |
M0209782 |
PKENNHKI_00660 |
758613 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
759C>T |
Ile253Ile |
M0209783 |
PKENNHKI_00054 |
47911 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
2730A>G |
Glu910Glu |
M0209784 |
PKENNHKI_00054 |
48040 |
5 |
Gut |
0.06 |
protein_coding |
synonymous_variant |
LOW |
2601C>T |
Arg867Arg |
M0209785 |
PKENNHKI_00054 |
48043 |
5 |
Gut |
0.06 |
protein_coding |
synonymous_variant |
LOW |
2598C>T |
Arg866Arg |
M0209786 |
PKENNHKI_00054 |
48151 |
7 |
Gut |
0.09 |
protein_coding |
synonymous_variant |
LOW |
2490T>C |
Gly830Gly |
M0209787 |
PKENNHKI_00054 |
48193 |
6 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
2448C>T |
Ser816Ser |
M0209788 |
PKENNHKI_00054 |
48199 |
6 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
2442T>C |
Ile814Ile |
M0209789 |
PKENNHKI_00054 |
48262 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
2379C>T |
Asp793Asp |
M0209790 |
PKENNHKI_00054 |
48265 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
2376C>T |
Asp792Asp |
M0209791 |
PKENNHKI_00054 |
48283 |
8 |
Gut |
0.10 |
protein_coding |
synonymous_variant |
LOW |
2358A>G |
Gln786Gln |
M0209792 |
PKENNHKI_00054 |
48349 |
5 |
Gut |
0.06 |
protein_coding |
synonymous_variant |
LOW |
2292G>A |
Glu764Glu |
M0209793 |
PKENNHKI_00054 |
48394 |
8 |
Gut |
0.10 |
protein_coding |
synonymous_variant |
LOW |
2247T>C |
Ala749Ala |
M0209794 |
PKENNHKI_00054 |
48421 |
8 |
Gut |
0.10 |
protein_coding |
synonymous_variant |
LOW |
2220T>C |
Ile740Ile |
M0209795 |
PKENNHKI_00054 |
48460 |
5 |
Gut |
0.06 |
protein_coding |
synonymous_variant |
LOW |
2181C>G |
Pro727Pro |
M0209796 |
PKENNHKI_00054 |
48475 |
5 |
Gut |
0.06 |
protein_coding |
synonymous_variant |
LOW |
2166T>G |
Val722Val |
M0209797 |
PKENNHKI_00054 |
48484 |
8 |
Gut |
0.10 |
protein_coding |
synonymous_variant |
LOW |
2157T>C |
His719His |
M0209798 |
PKENNHKI_00054 |
48487 |
5 |
Gut |
0.06 |
protein_coding |
synonymous_variant |
LOW |
2154T>C |
Ile718Ile |
M0209799 |
PKENNHKI_00054 |
48511 |
5 |
Gut |
0.06 |
protein_coding |
synonymous_variant |
LOW |
2130A>T |
Ala710Ala |
M0209800 |
PKENNHKI_00054 |
48562 |
8 |
Gut |
0.10 |
protein_coding |
synonymous_variant |
LOW |
2079T>C |
Asp693Asp |
M0209801 |
PKENNHKI_00054 |
48583 |
5 |
Gut |
0.06 |
protein_coding |
synonymous_variant |
LOW |
2058T>C |
Ile686Ile |
M0209802 |
PKENNHKI_00054 |
48685 |
7 |
Gut |
0.09 |
protein_coding |
synonymous_variant |
LOW |
1956A>G |
Glu652Glu |
M0209803 |
PKENNHKI_00054 |
48745 |
8 |
Gut |
0.10 |
protein_coding |
synonymous_variant |
LOW |
1896A>G |
Gln632Gln |
M0209804 |
PKENNHKI_00054 |
48763 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
1878G>A |
Val626Val |
M0209805 |
PKENNHKI_00054 |
48766 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
1875C>T |
Pro625Pro |
M0209806 |
PKENNHKI_00054 |
48772 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
1869T>C |
Tyr623Tyr |
M0209807 |
PKENNHKI_00054 |
48775 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
1866C>T |
Leu622Leu |
M0209808 |
PKENNHKI_00054 |
48808 |
7 |
Gut |
0.09 |
protein_coding |
synonymous_variant |
LOW |
1833T>C |
Val611Val |
M0209809 |
PKENNHKI_00053 |
47093 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
768T>C |
Gly256Gly |
M0209810 |
PKENNHKI_00053 |
47378 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
483A>C |
Arg161Arg |
M0209811 |
PKENNHKI_00053 |
47558 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
303T>C |
Arg101Arg |
M0209812 |
PKENNHKI_00053 |
47606 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
255G>T |
Ser85Ser |
M0209813 |
PKENNHKI_00053 |
47633 |
6 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
228T>C |
Asp76Asp |
M0209814 |
PKENNHKI_00053 |
47795 |
6 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
66A>G |
Gln22Gln |
M0209815 |
PKENNHKI_00054 |
48577 |
6 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
2064C>T |
Ile688Ile |
M0209816 |
PKENNHKI_00054 |
48591 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
2050C>T |
Leu684Leu |
M0209817 |
PKENNHKI_00054 |
48655 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
1986C>T |
Tyr662Tyr |
M0209818 |
PKENNHKI_00054 |
48664 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
1977C>T |
Ile659Ile |
M0209819 |
PKENNHKI_00054 |
48673 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
1968G>T |
Val656Val |
M0209820 |
PKENNHKI_00054 |
48679 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
1962C>T |
Leu654Leu |
M0209821 |
PKENNHKI_00054 |
48682 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
1959T>C |
Arg653Arg |
M0209822 |
PKENNHKI_00054 |
48883 |
5 |
Gut |
0.06 |
protein_coding |
synonymous_variant |
LOW |
1758T>C |
Asn586Asn |
M0209823 |
PKENNHKI_00054 |
48922 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
1719C>T |
Ile573Ile |
M0209824 |
PKENNHKI_00054 |
48958 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
1683T>C |
Val561Val |
M0209825 |
PKENNHKI_00054 |
48961 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
1680T>G |
Pro560Pro |
M0209826 |
PKENNHKI_00660 |
758751 |
13 |
Gut |
0.16 |
protein_coding |
synonymous_variant |
LOW |
897C>G |
Thr299Thr |
M0209827 |
PKENNHKI_00660 |
758928 |
9 |
Gut |
0.11 |
protein_coding |
synonymous_variant |
LOW |
1074G>A |
Val358Val |
M0209828 |
PKENNHKI_00660 |
758994 |
12 |
Gut |
0.15 |
protein_coding |
synonymous_variant |
LOW |
1140C>T |
Ala380Ala |
M0209829 |
PKENNHKI_00660 |
759000 |
13 |
Gut |
0.16 |
protein_coding |
synonymous_variant |
LOW |
1146C>T |
Pro382Pro |
M0209830 |
PKENNHKI_00660 |
759141 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
1287G>A |
Glu429Glu |
M0209831 |
PKENNHKI_00660 |
759194 |
6 |
Gut |
0.07 |
protein_coding |
missense_variant |
MODERATE |
1340A>G |
Asp447Gly |
M0209832 |
PKENNHKI_00660 |
759196 |
6 |
Gut |
0.07 |
protein_coding |
missense_variant |
MODERATE |
1342G>A |
Ala448Thr |
M0209833 |
PKENNHKI_00660 |
759229 |
4 |
Gut |
0.05 |
protein_coding |
missense_variant |
MODERATE |
1375T>G |
Ser459Ala |
M0209834 |
PKENNHKI_00660 |
759315 |
6 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
1461T>C |
Asp487Asp |
M0209835 |
PKENNHKI_00660 |
759321 |
7 |
Gut |
0.09 |
protein_coding |
synonymous_variant |
LOW |
1467C>T |
Asp489Asp |
M0209836 |
PKENNHKI_00660 |
759396 |
7 |
Gut |
0.09 |
protein_coding |
synonymous_variant |
LOW |
1542C>T |
Ala514Ala |
M0209837 |
PKENNHKI_00660 |
759399 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
1545G>A |
Ala515Ala |
M0209838 |
PKENNHKI_00660 |
759495 |
7 |
Gut |
0.09 |
protein_coding |
synonymous_variant |
LOW |
1641T>C |
Val547Val |
M0209839 |
PKENNHKI_00661 |
759910 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
201C>T |
Arg67Arg |
M0209840 |
PKENNHKI_00661 |
759991 |
5 |
Gut |
0.06 |
protein_coding |
synonymous_variant |
LOW |
282T>C |
Gly94Gly |
M0209841 |
PKENNHKI_00661 |
760204 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
495T>C |
Ile165Ile |
M0209842 |
PKENNHKI_00661 |
760210 |
5 |
Gut |
0.06 |
protein_coding |
synonymous_variant |
LOW |
501A>G |
Ala167Ala |
M0209843 |
PKENNHKI_00372 |
434325 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
1416T>C |
Ala472Ala |
M0209844 |
PKENNHKI_00372 |
434364 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
1377T>C |
Arg459Arg |
M0209845 |
PKENNHKI_00372 |
434523 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
1218A>G |
Thr406Thr |
M0209846 |
PKENNHKI_00372 |
434615 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
1126A>G |
Ile376Val |
M0209847 |
PKENNHKI_00372 |
434703 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
1038A>G |
Ala346Ala |
M0209848 |
PKENNHKI_00372 |
434802 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
939T>C |
Tyr313Tyr |
M0209849 |
PKENNHKI_00659 |
757343 |
5 |
Gut |
0.06 |
protein_coding |
synonymous_variant |
LOW |
228C>T |
Gly76Gly |
M0209850 |
PKENNHKI_00659 |
757447 |
4 |
Gut |
0.05 |
protein_coding |
missense_variant |
MODERATE |
124G>T |
Ala42Ser |
M0209851 |
PKENNHKI_00659 |
757526 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
45G>T |
Ala15Ala |
M0209852 |
PKENNHKI_00659 |
757544 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
27C>T |
Asn9Asn |
M0209853 |
PKENNHKI_00659 |
757599 |
3 |
Gut |
0.04 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-29C>T |
None |
M0209854 |
PKENNHKI_00659 |
757688 |
5 |
Gut |
0.06 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-118T>A |
None |
M0209855 |
PKENNHKI_00660 |
757986 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
132T>C |
Phe44Phe |
M0209856 |
PKENNHKI_00660 |
758016 |
9 |
Gut |
0.11 |
protein_coding |
synonymous_variant |
LOW |
162C>T |
Val54Val |
M0209857 |
PKENNHKI_00660 |
758184 |
6 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
330G>T |
Val110Val |
M0209858 |
PKENNHKI_00660 |
758239 |
9 |
Gut |
0.11 |
protein_coding |
missense_variant |
MODERATE |
385G>A |
Asp129Asn |
M0209859 |
PKENNHKI_00660 |
758433 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
579C>T |
Ala193Ala |
M0209860 |
PKENNHKI_00660 |
758529 |
5 |
Gut |
0.06 |
protein_coding |
synonymous_variant |
LOW |
675C>T |
Thr225Thr |
M0209861 |
PKENNHKI_00660 |
758532 |
5 |
Gut |
0.06 |
protein_coding |
synonymous_variant |
LOW |
678T>G |
Ala226Ala |
M0209862 |
PKENNHKI_00660 |
758538 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
684A>G |
Glu228Glu |
M0209863 |
PKENNHKI_00660 |
758544 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
690T>C |
Tyr230Tyr |
M0209864 |
PKENNHKI_00660 |
758547 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
693T>C |
Pro231Pro |
M0209865 |
PKENNHKI_00660 |
758550 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
696C>A |
Gly232Gly |
M0209866 |
PKENNHKI_00660 |
758553 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
699T>C |
Leu233Leu |
M0209867 |
PKENNHKI_00660 |
758562 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
708C>T |
Ile236Ile |
M0209868 |
PKENNHKI_00660 |
758724 |
10 |
Gut |
0.12 |
protein_coding |
synonymous_variant |
LOW |
870A>G |
Val290Val |
M0209869 |
PKENNHKI_00660 |
758952 |
8 |
Gut |
0.10 |
protein_coding |
synonymous_variant |
LOW |
1098T>C |
Asp366Asp |
M0209870 |
PKENNHKI_00053 |
47552 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
309G>T |
Ser103Ser |
M0209871 |
PKENNHKI_00054 |
49084 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
1557T>C |
Thr519Thr |
M0209872 |
PKENNHKI_00054 |
49093 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
1548T>C |
Ile516Ile |
M0209873 |
PKENNHKI_00660 |
758460 |
8 |
Gut |
0.10 |
protein_coding |
synonymous_variant |
LOW |
606G>C |
Val202Val |
M0209874 |
PKENNHKI_00660 |
758463 |
8 |
Gut |
0.10 |
protein_coding |
synonymous_variant |
LOW |
609T>C |
Val203Val |
M0209875 |
PKENNHKI_00660 |
758682 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
828T>C |
Gly276Gly |
M0209876 |
PKENNHKI_00660 |
758850 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
996A>G |
Glu332Glu |
M0209877 |
PKENNHKI_00660 |
759042 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
1188C>T |
Ile396Ile |
M0209878 |
PKENNHKI_00660 |
759126 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
1272C>T |
Cys424Cys |
M0209879 |
PKENNHKI_00660 |
759372 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
1518T>C |
Leu506Leu |
M0209880 |
PKENNHKI_00660 |
759585 |
5 |
Gut |
0.06 |
protein_coding |
synonymous_variant |
LOW |
1731T>C |
Thr577Thr |
M0209881 |
PKENNHKI_00661 |
759772 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
63G>A |
Gln21Gln |
M0209882 |
PKENNHKI_00661 |
759856 |
6 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
147T>C |
Asp49Asp |
M0209883 |
PKENNHKI_00661 |
759952 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
243C>T |
Arg81Arg |
M0209884 |
PKENNHKI_00661 |
760030 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
321A>T |
Lys107Asn |
M0209885 |
PKENNHKI_00661 |
760084 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
375T>C |
Phe125Phe |
M0209886 |
PKENNHKI_00661 |
760095 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
386G>A |
Gly129Asp |
M0209887 |
PKENNHKI_00661 |
760132 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
423C>T |
Ala141Ala |
M0209888 |
PKENNHKI_00661 |
760404 |
5 |
Gut |
0.06 |
protein_coding |
missense_variant |
MODERATE |
695A>G |
Asn232Ser |
M0209889 |
PKENNHKI_00661 |
760408 |
5 |
Gut |
0.06 |
protein_coding |
synonymous_variant |
LOW |
699C>T |
Ala233Ala |
M0209890 |
PKENNHKI_00661 |
760423 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
714A>C |
Ala238Ala |
M0209891 |
PKENNHKI_00661 |
760426 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
717T>C |
Ala239Ala |
M0209892 |
PKENNHKI_00661 |
760549 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
840C>T |
Val280Val |
M0209893 |
PKENNHKI_00661 |
760721 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
1012T>G |
Ser338Ala |
M0209894 |
PKENNHKI_00661 |
760741 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
1032A>T |
Val344Val |
M0209895 |
PKENNHKI_00661 |
760798 |
6 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
1089G>C |
Leu363Leu |
M0209896 |
PKENNHKI_00661 |
760891 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
1182C>T |
Asp394Asp |
M0209897 |
PKENNHKI_00661 |
760912 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
1203C>T |
Tyr401Tyr |
M0209898 |
PKENNHKI_00661 |
760945 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
1236A>G |
Ala412Ala |
M0209899 |
PKENNHKI_00661 |
760948 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
1239C>T |
Ile413Ile |
M0209900 |
PKENNHKI_00661 |
761020 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
1311T>C |
Tyr437Tyr |
M0209901 |
PKENNHKI_00661 |
761026 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
1317A>G |
Lys439Lys |
M0209902 |
PKENNHKI_00661 |
761029 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
1320T>C |
Arg440Arg |
M0209903 |
PKENNHKI_00660 |
759222 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
1368C>T |
Ala456Ala |
M0209904 |
PKENNHKI_00660 |
759324 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
1470C>T |
Gly490Gly |
M0209905 |
PKENNHKI_00661 |
759994 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
285C>T |
Val95Val |
M0209906 |
PKENNHKI_00661 |
760012 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
303T>C |
Leu101Leu |
M0209907 |
PKENNHKI_00661 |
760015 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
306C>T |
Phe102Phe |
M0209908 |
PKENNHKI_00661 |
760189 |
6 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
480C>T |
Phe160Phe |
M0209909 |
PKENNHKI_00661 |
760192 |
6 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
483G>C |
Thr161Thr |
M0209910 |
PKENNHKI_00656 |
756325 |
8 |
Gut |
0.10 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-3730C>T |
None |
M0209911 |
PKENNHKI_00656 |
756347 |
7 |
Gut |
0.09 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-3752T>A |
None |
M0209912 |
PKENNHKI_00656 |
756368 |
7 |
Gut |
0.09 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-3773G>A |
None |
M0209913 |
PKENNHKI_00660 |
757918 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
64A>G |
Ile22Val |
M0209914 |
PKENNHKI_00660 |
757935 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
81C>T |
Ile27Ile |
M0209915 |
PKENNHKI_00660 |
758026 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
172C>T |
Leu58Leu |
M0209916 |
PKENNHKI_00660 |
758109 |
5 |
Gut |
0.06 |
protein_coding |
synonymous_variant |
LOW |
255C>T |
Thr85Thr |
M0209917 |
PKENNHKI_00660 |
758685 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
831C>T |
Gly277Gly |
M0209918 |
PKENNHKI_00660 |
759027 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
1173G>A |
Thr391Thr |
M0209919 |
PKENNHKI_00660 |
757914 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
60G>A |
Arg20Arg |
M0209920 |
PKENNHKI_00660 |
757938 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
84G>A |
Lys28Lys |
M0209921 |
PKENNHKI_00660 |
758121 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
267C>T |
Phe89Phe |
M0209922 |
PKENNHKI_00660 |
759051 |
6 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
1197A>G |
Val399Val |
M0209923 |
PKENNHKI_00660 |
759060 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
1206G>A |
Ala402Ala |
M0209924 |
PKENNHKI_00660 |
759483 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
1629T>C |
Leu543Leu |
M0209925 |
PKENNHKI_00560 |
632067 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
930T>C |
Ile310Ile |
M0209926 |
PKENNHKI_00560 |
632100 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
897C>T |
Ala299Ala |
M0209927 |
PKENNHKI_00560 |
632175 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
822T>C |
Val274Val |
M0209928 |
PKENNHKI_00642 |
739484 |
4 |
Gut |
0.05 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4419A>T |
None |
M0209929 |
PKENNHKI_00642 |
739517 |
3 |
Gut |
0.04 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4452G>A |
None |
M0209930 |
PKENNHKI_00642 |
739534 |
4 |
Gut |
0.05 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4469T>C |
None |
M0209931 |
PKENNHKI_00642 |
739595 |
4 |
Gut |
0.05 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4530A>G |
None |
M0209932 |
PKENNHKI_00646 |
739716 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
23C>A |
Ala8Glu |
M0209933 |
PKENNHKI_00646 |
739954 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
261A>G |
Thr87Thr |
M0209934 |
PKENNHKI_00646 |
740110 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
417T>C |
Ile139Ile |
M0209935 |
PKENNHKI_00646 |
740119 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
426T>C |
Leu142Leu |
M0209936 |
PKENNHKI_00646 |
740353 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
660C>T |
Tyr220Tyr |
M0209937 |
PKENNHKI_00646 |
740466 |
4 |
Gut |
0.05 |
protein_coding |
missense_variant |
MODERATE |
773T>C |
Val258Ala |
M0209938 |
PKENNHKI_00660 |
759474 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
1620T>C |
Val540Val |
M0209939 |
PKENNHKI_00660 |
759534 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
1680C>T |
Arg560Arg |
M0209940 |
PKENNHKI_00661 |
760123 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
414G>C |
Thr138Thr |
M0209941 |
PKENNHKI_00661 |
760582 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
873G>A |
Ala291Ala |
M0209942 |
PKENNHKI_00054 |
48436 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
2205C>T |
Leu735Leu |
M0209943 |
PKENNHKI_00054 |
48565 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
2076G>T |
Ser692Ser |
M0209944 |
PKENNHKI_00054 |
48867 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
1774C>T |
Leu592Leu |
M0209945 |
PKENNHKI_00642 |
739565 |
3 |
Gut |
0.04 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4500T>G |
None |
M0209946 |
PKENNHKI_00646 |
740953 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
1260T>C |
Asn420Asn |
M0209947 |
PKENNHKI_00659 |
756659 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
912T>C |
Val304Val |
M0209948 |
PKENNHKI_00659 |
757094 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
477C>T |
Val159Val |
M0209949 |
PKENNHKI_00660 |
758604 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
750C>T |
Gly250Gly |
M0209950 |
PKENNHKI_00660 |
758697 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
843C>T |
His281His |
M0209951 |
PKENNHKI_00054 |
48217 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
2424C>A |
Pro808Pro |
M0209952 |
PKENNHKI_00054 |
48223 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
2418C>T |
Ser806Ser |
M0209953 |
PKENNHKI_00660 |
759555 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
1701C>T |
Ala567Ala |
M0209954 |
PKENNHKI_00660 |
759558 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
1704G>C |
Pro568Pro |
M0209955 |
PKENNHKI_00661 |
759931 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
222C>T |
Arg74Arg |
M0209956 |
PKENNHKI_00661 |
760504 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
795G>A |
Glu265Glu |
M0209957 |
PKENNHKI_00659 |
757442 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
129C>A |
Ala43Ala |
M0209958 |
PKENNHKI_00659 |
757523 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
48T>C |
Gly16Gly |
M0209959 |
PKENNHKI_00659 |
757115 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
456A>G |
Glu152Glu |
M0209960 |
PKENNHKI_00659 |
757154 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
417G>T |
Ala139Ala |
M0209961 |
PKENNHKI_00659 |
757076 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
495C>T |
Gly165Gly |
M0209962 |
PKENNHKI_00659 |
757148 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
423A>G |
Lys141Lys |
Analysis of virulence factors contributing to bacterial pathogenicity
This table presents virulence factors identified within the plasmid cluster.
Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.
Gene Name |
vf_gene_id |
vf_name |
identity |
evalue |
qstart |
qend |
query_coverage |
subject_coverage |
vf_category |
gene_description |
condition |
PKENNHKI_00508 |
VFG046465 |
EF-Tu |
71.5 |
6e-172 |
1 |
396 |
1.0 |
1.0051 |
Adherence |
elongation factor Tu |
experiment |
PKENNHKI_00508 |
VFG046459 |
EF-Tu |
72 |
6.9e-172 |
1 |
396 |
1.0 |
1.0051 |
Adherence |
elongation factor Tu |
prediction |
Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact
This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.
Gene Name |
compound |
identity |
evalue |
qstart |
qend |
query_coverage |
subject_coverage |
group |
Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents
This table presents antimicrobial resistance genes identified within the plasmid cluster.
Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.
Gene Name |
aro_accession |
identity |
evalue |
qstart |
qend |
query_coverage |
subject_coverage |
drug_class |
amr_gene_family |
resistance_mechanism |
PKENNHKI_00477 |
ARO:3003395 |
72.4 |
6.53e-59 |
1 |
123 |
0.9840 |
0.9919 |
aminoglycoside antibiotic |
antibiotic-resistant rpsL |
antibiotic target alteration |
PKENNHKI_00508 |
ARO:3003438 |
74.2 |
3.89e-221 |
1 |
394 |
0.9975 |
0.9338 |
elfamycin antibiotic |
elfamycin resistant EF-Tu |
antibiotic target alteration |
Analysis of pathogenicity genes to explore pathogen-host interactions
This table presents host pathogen-host interactions within the plasmid cluster.
Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.
Gene Name |
phi_molconn_id |
host gene_name |
identity |
evalue |
qstart |
qend |
query_coverage |
subject_coverage |
host_descripton |
disease_name |
function |
phenotype_of_mutant |
PKENNHKI_00508 |
PHI:10282 |
tufA |
70.5 |
1.3e-168 |
1 |
396 |
1.0000 |
1.0000 |
primates |
skin infection; food poisoning; respiratory disease |
elongation factor Tu |
increased virulence (hypervirulence) |
Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation
This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.
Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification
This table presents transport proteins within the plasmid cluster.
Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.
Gene Name |
tcid |
identity |
evalue |
qstart |
qend |
query_coverage |
subject_coverage |
class_field |
class_term |
subclass |
subclass_term |
family |
family_term |