Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1424
  Reference Plasmid   NZ_OY725724.1
  Reference Plasmid Size   1100
  Reference Plasmid GC Content   0.68
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0210094 NMEDELKG_00001 128 7 Gut 0.54 protein_coding missense_variant MODERATE 755A>G Glu252Gly
M0210095 NMEDELKG_00001 253 4 Gut 0.31 protein_coding synonymous_variant LOW 630C>T Ser210Ser
M0210096 NMEDELKG_00001 259 5 Gut 0.38 protein_coding synonymous_variant LOW 624C>T Leu208Leu
M0210097 NMEDELKG_00001 640 3 Gut 0.23 protein_coding synonymous_variant LOW 243C>T Gly81Gly
M0210098 NMEDELKG_00001 124 7 Gut 0.54 protein_coding synonymous_variant LOW 759T>C Leu253Leu
M0210099 NMEDELKG_00002 1034 3 Gut 0.23 protein_coding missense_variant MODERATE 58A>G Thr20Ala
M0210100 NMEDELKG_00001 51 5 Gut 0.38 protein_coding downstream_gene_variant MODIFIER *4T>A None
M0210101 NMEDELKG_00001 53 5 Gut 0.38 protein_coding downstream_gene_variant MODIFIER *2A>G None
M0210102 NMEDELKG_00002 939 5 Gut 0.38 protein_coding synonymous_variant LOW 153A>G Gln51Gln
M0210103 NMEDELKG_00001 361 3 Gut 0.23 protein_coding synonymous_variant LOW 522T>G Val174Val
M0210104 NMEDELKG_00001 460 3 Gut 0.23 protein_coding synonymous_variant LOW 423A>C Ile141Ile
M0210105 NMEDELKG_00001 742 3 Gut 0.23 protein_coding synonymous_variant LOW 141A>C Ala47Ala
M0210106 NMEDELKG_00002 923 3 Gut 0.23 protein_coding missense_variant MODERATE 169A>G Thr57Ala
M0210107 NMEDELKG_00002 926 3 Gut 0.23 protein_coding synonymous_variant LOW 166A>C Arg56Arg
M0210108 NMEDELKG_00002 957 3 Gut 0.23 protein_coding synonymous_variant LOW 135G>C Val45Val






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term