Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1425
  Reference Plasmid   NZ_OY725727.1
  Reference Plasmid Size   55380
  Reference Plasmid GC Content   0.39
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0210109 AIFOHCEO_00012 12160 3 Gut 0.43 protein_coding synonymous_variant LOW 93T>C Gly31Gly
M0210110 AIFOHCEO_00012 12427 4 Gut 0.57 protein_coding synonymous_variant LOW 360T>C Gly120Gly
M0210111 AIFOHCEO_00012 12538 4 Gut 0.57 protein_coding synonymous_variant LOW 471C>T Gly157Gly
M0210112 AIFOHCEO_00012 12803 4 Gut 0.57 protein_coding missense_variant MODERATE 736C>G Gln246Glu
M0210113 AIFOHCEO_00013 13028 4 Gut 0.57 protein_coding synonymous_variant LOW 165A>T Gly55Gly
M0210114 AIFOHCEO_00013 13167 4 Gut 0.57 protein_coding synonymous_variant LOW 304C>T Leu102Leu
M0210115 AIFOHCEO_00013 13215 4 Gut 0.57 protein_coding missense_variant MODERATE 352A>G Thr118Ala
M0210116 AIFOHCEO_00013 13248 4 Gut 0.57 protein_coding missense_variant MODERATE 385G>A Ala129Thr
M0210117 AIFOHCEO_00013 13525 4 Gut 0.57 protein_coding missense_variant MODERATE 662T>C Ile221Thr
M0210118 AIFOHCEO_00014 13950 4 Gut 0.57 protein_coding synonymous_variant LOW 321G>A Gly107Gly
M0210119 AIFOHCEO_00014 13964 4 Gut 0.57 protein_coding missense_variant MODERATE 335C>T Thr112Ile
M0210120 AIFOHCEO_00018 14502 4 Gut 0.57 protein_coding upstream_gene_variant MODIFIER -2007C>T None
M0210121 AIFOHCEO_00016 14728 4 Gut 0.57 protein_coding missense_variant MODERATE 90A>C Glu30Asp
M0210122 AIFOHCEO_00017 15405 4 Gut 0.57 protein_coding synonymous_variant LOW 930C>T Ile310Ile
M0210123 AIFOHCEO_00017 15414 4 Gut 0.57 protein_coding synonymous_variant LOW 921T>A Gly307Gly
M0210124 AIFOHCEO_00017 15428 4 Gut 0.57 protein_coding missense_variant MODERATE 907T>A Cys303Ser
M0210125 AIFOHCEO_00017 15583 4 Gut 0.57 protein_coding missense_variant MODERATE 752A>G Lys251Arg
M0210126 AIFOHCEO_00017 15671 4 Gut 0.57 protein_coding missense_variant MODERATE 664A>G Ile222Val
M0210127 AIFOHCEO_00017 15683 4 Gut 0.57 protein_coding missense_variant MODERATE 652A>G Asn218Asp
M0210128 AIFOHCEO_00017 15687 4 Gut 0.57 protein_coding synonymous_variant LOW 648G>T Gly216Gly
M0210129 AIFOHCEO_00017 15698 4 Gut 0.57 protein_coding missense_variant MODERATE 637A>T Ile213Leu
M0210130 AIFOHCEO_00017 15706 4 Gut 0.57 protein_coding missense_variant MODERATE 629T>C Ile210Thr
M0210131 AIFOHCEO_00017 15711 4 Gut 0.57 protein_coding synonymous_variant LOW 624G>A Ser208Ser
M0210132 AIFOHCEO_00017 15729 4 Gut 0.57 protein_coding synonymous_variant LOW 606T>C Ser202Ser
M0210133 AIFOHCEO_00017 15773 4 Gut 0.57 protein_coding missense_variant MODERATE 562G>A Val188Ile
M0210134 AIFOHCEO_00017 15894 4 Gut 0.57 protein_coding synonymous_variant LOW 441G>A Gln147Gln
M0210135 AIFOHCEO_00017 15897 4 Gut 0.57 protein_coding synonymous_variant LOW 438G>A Arg146Arg
M0210136 AIFOHCEO_00017 16089 4 Gut 0.57 protein_coding synonymous_variant LOW 246T>C Asp82Asp
M0210137 AIFOHCEO_00017 16125 4 Gut 0.57 protein_coding synonymous_variant LOW 210A>C Val70Val
M0210138 AIFOHCEO_00017 16197 4 Gut 0.57 protein_coding synonymous_variant LOW 138G>T Ala46Ala
M0210139 AIFOHCEO_00017 16242 4 Gut 0.57 protein_coding synonymous_variant LOW 93A>G Gly31Gly
M0210140 AIFOHCEO_00017 16248 4 Gut 0.57 protein_coding synonymous_variant LOW 87A>C Ile29Ile
M0210141 AIFOHCEO_00016 16413 4 Gut 0.57 protein_coding upstream_gene_variant MODIFIER -1596A>T None
M0210142 AIFOHCEO_00040 39350 3 Gut 0.43 protein_coding upstream_gene_variant MODIFIER -225T>C None
M0210143 AIFOHCEO_00041 39451 3 Gut 0.43 protein_coding synonymous_variant LOW 375C>T Gly125Gly
M0210144 AIFOHCEO_00041 39454 3 Gut 0.43 protein_coding synonymous_variant LOW 372T>C Ile124Ile
M0210145 AIFOHCEO_00041 39523 3 Gut 0.43 protein_coding missense_variant MODERATE 303A>C Glu101Asp
M0210146 AIFOHCEO_00041 39541 3 Gut 0.43 protein_coding synonymous_variant LOW 285A>C Gly95Gly
M0210147 AIFOHCEO_00041 39801 3 Gut 0.43 protein_coding missense_variant MODERATE 25C>T Leu9Phe
M0210148 AIFOHCEO_00040 39915 3 Gut 0.43 protein_coding upstream_gene_variant MODIFIER -790A>C None
M0210149 AIFOHCEO_00040 39982 3 Gut 0.43 protein_coding upstream_gene_variant MODIFIER -857A>G None
M0210150 AIFOHCEO_00040 39991 3 Gut 0.43 protein_coding upstream_gene_variant MODIFIER -866A>G None
M0210151 AIFOHCEO_00040 40016 3 Gut 0.43 protein_coding upstream_gene_variant MODIFIER -891G>A None
M0210152 AIFOHCEO_00040 40020 3 Gut 0.43 protein_coding upstream_gene_variant MODIFIER -895G>C None
M0210153 AIFOHCEO_00042 40366 3 Gut 0.43 protein_coding synonymous_variant LOW 675T>C Leu225Leu
M0210154 AIFOHCEO_00042 40385 3 Gut 0.43 protein_coding missense_variant MODERATE 656G>T Arg219Met
M0210155 AIFOHCEO_00042 40948 3 Gut 0.43 protein_coding synonymous_variant LOW 93G>A Gln31Gln






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
AIFOHCEO_00018 AUO19159.1|GH95 98.8 0 1 1303 1 1
AIFOHCEO_00037 AUO19144.1|CE4 99.2 1.96e-235 1 366 1 1
AIFOHCEO_00055 AUO19127.1|GH140 99.5 0 1 433 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term