Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1432
  Reference Plasmid   NZ_OY725769.1
  Reference Plasmid Size   41267
  Reference Plasmid GC Content   0.43
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0210788 FFOPGCKB_00009 11422 48 Gut 0.37 protein_coding upstream_gene_variant MODIFIER -2311C>T None
M0210789 FFOPGCKB_00009 11424 48 Gut 0.37 protein_coding upstream_gene_variant MODIFIER -2313C>T None
M0210790 FFOPGCKB_00009 11458 47 Gut 0.36 protein_coding upstream_gene_variant MODIFIER -2347C>T None
M0210791 FFOPGCKB_00009 11464 47 Gut 0.36 protein_coding upstream_gene_variant MODIFIER -2353T>C None
M0210792 FFOPGCKB_00009 11480 47 Gut 0.36 protein_coding upstream_gene_variant MODIFIER -2369T>C None
M0210793 FFOPGCKB_00009 11481 47 Gut 0.36 protein_coding upstream_gene_variant MODIFIER -2370T>C None
M0210794 FFOPGCKB_00009 11655 46 Gut 0.35 protein_coding upstream_gene_variant MODIFIER -2544A>T None
M0210795 FFOPGCKB_00009 11661 46 Gut 0.35 protein_coding upstream_gene_variant MODIFIER -2550T>C None
M0210796 FFOPGCKB_00009 11827 29 Gut 0.22 protein_coding upstream_gene_variant MODIFIER -2716A>G None
M0210797 FFOPGCKB_00018 15453 3 Gut 0.02 protein_coding missense_variant MODERATE 344C>T Pro115Leu
M0210798 FFOPGCKB_00021 17975 7 Gut 0.05 protein_coding missense_variant MODERATE 910G>A Glu304Lys
M0210799 FFOPGCKB_00023 18590 18 Gut 0.14 protein_coding missense_variant MODERATE 916A>G Ile306Val
M0210800 FFOPGCKB_00003 1984 8 Gut 0.06 protein_coding missense_variant MODERATE 68T>C Phe23Ser
M0210801 FFOPGCKB_00006 5024 9 Gut 0.07 protein_coding missense_variant MODERATE 665A>T Gln222Leu
M0210802 FFOPGCKB_00006 5298 8 Gut 0.06 protein_coding stop_gained HIGH 939C>A Tyr313*
M0210803 FFOPGCKB_00006 5344 5 Gut 0.04 protein_coding missense_variant MODERATE 985C>T Leu329Phe
M0210804 FFOPGCKB_00006 5720 9 Gut 0.07 protein_coding missense_variant MODERATE 1361T>C Ile454Thr
M0210805 FFOPGCKB_00006 5886 8 Gut 0.06 protein_coding synonymous_variant LOW 1527C>T Thr509Thr
M0210806 FFOPGCKB_00007 6858 7 Gut 0.05 protein_coding upstream_gene_variant MODIFIER -38C>T None
M0210807 FFOPGCKB_00009 9595 34 Gut 0.26 protein_coding upstream_gene_variant MODIFIER -484G>A None
M0210808 FFOPGCKB_00012 13016 6 Gut 0.05 protein_coding synonymous_variant LOW 468A>G Pro156Pro
M0210809 FFOPGCKB_00011 16196 6 Gut 0.05 protein_coding upstream_gene_variant MODIFIER -4997T>C None
M0210810 FFOPGCKB_00001 751 18 Gut 0.14 protein_coding missense_variant MODERATE 694A>G Lys232Glu
M0210811 FFOPGCKB_00001 984 21 Gut 0.16 protein_coding synonymous_variant LOW 927T>C Tyr309Tyr
M0210812 FFOPGCKB_00003 2201 22 Gut 0.17 protein_coding synonymous_variant LOW 285A>T Pro95Pro
M0210813 FFOPGCKB_00004 2888 62 Gut 0.48 protein_coding missense_variant MODERATE 384A>C Lys128Asn
M0210814 FFOPGCKB_00001 63 3 Gut 0.02 protein_coding synonymous_variant LOW 6A>G Leu2Leu
M0210815 FFOPGCKB_00001 357 4 Gut 0.03 protein_coding synonymous_variant LOW 300A>G Ser100Ser
M0210816 FFOPGCKB_00001 387 3 Gut 0.02 protein_coding synonymous_variant LOW 330C>T Phe110Phe
M0210817 FFOPGCKB_00001 1027 3 Gut 0.02 protein_coding missense_variant MODERATE 970T>C Ser324Pro
M0210818 FFOPGCKB_00001 1080 3 Gut 0.02 protein_coding synonymous_variant LOW 1023C>T Ala341Ala
M0210819 FFOPGCKB_00001 1190 3 Gut 0.02 protein_coding missense_variant MODERATE 1133T>C Ile378Thr
M0210820 FFOPGCKB_00002 1209 3 Gut 0.02 protein_coding missense_variant MODERATE 61A>G Thr21Ala
M0210821 FFOPGCKB_00002 1403 3 Gut 0.02 protein_coding synonymous_variant LOW 255A>C Gly85Gly
M0210822 FFOPGCKB_00001 185 5 Gut 0.04 protein_coding missense_variant MODERATE 128T>C Val43Ala
M0210823 FFOPGCKB_00010 15035 7 Gut 0.05 protein_coding upstream_gene_variant MODIFIER -4323T>A None
M0210824 FFOPGCKB_00010 15037 7 Gut 0.05 protein_coding upstream_gene_variant MODIFIER -4325A>T None
M0210825 FFOPGCKB_00010 10467 5 Gut 0.04 protein_coding synonymous_variant LOW 246T>A Gly82Gly
M0210826 FFOPGCKB_00021 18025 3 Gut 0.02 protein_coding synonymous_variant LOW 960T>C Asn320Asn
M0210827 FFOPGCKB_00024 19836 14 Gut 0.11 protein_coding synonymous_variant LOW 1197G>A Glu399Glu
M0210828 FFOPGCKB_00024 20895 14 Gut 0.11 protein_coding synonymous_variant LOW 138T>G Thr46Thr
M0210829 FFOPGCKB_00025 21406 11 Gut 0.08 protein_coding synonymous_variant LOW 2988A>G Ser996Ser
M0210830 FFOPGCKB_00025 22156 11 Gut 0.08 protein_coding synonymous_variant LOW 2238T>C Ile746Ile
M0210831 FFOPGCKB_00025 22183 11 Gut 0.08 protein_coding synonymous_variant LOW 2211T>A Ala737Ala
M0210832 FFOPGCKB_00025 23659 9 Gut 0.07 protein_coding synonymous_variant LOW 735T>A Thr245Thr
M0210833 FFOPGCKB_00025 26701 4 Gut 0.03 protein_coding upstream_gene_variant MODIFIER -2308A>G None
M0210834 FFOPGCKB_00009 9052 4 Gut 0.03 protein_coding synonymous_variant LOW 60C>T Thr20Thr
M0210835 FFOPGCKB_00025 26898 3 Gut 0.02 protein_coding upstream_gene_variant MODIFIER -2505C>T None
M0210836 FFOPGCKB_00023 18885 5 Gut 0.04 protein_coding synonymous_variant LOW 621C>T His207His
M0210837 FFOPGCKB_00024 20881 4 Gut 0.03 protein_coding missense_variant MODERATE 152C>T Thr51Ile
M0210838 FFOPGCKB_00024 25686 3 Gut 0.02 protein_coding upstream_gene_variant MODIFIER -4654T>C None
M0210839 FFOPGCKB_00027 25965 3 Gut 0.02 protein_coding synonymous_variant LOW 189T>C Arg63Arg
M0210840 FFOPGCKB_00011 10957 4 Gut 0.03 protein_coding synonymous_variant LOW 243C>T Phe81Phe






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term