Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1437
  Reference Plasmid   NZ_OY725794.1
  Reference Plasmid Size   2638
  Reference Plasmid GC Content   0.47
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0210906 MICANLAO_00001 316 6 Gut 0.67 protein_coding missense_variant MODERATE 290C>T Ser97Phe
M0210907 MICANLAO_00002 601 7 Gut 0.78 protein_coding missense_variant MODERATE 160C>A Leu54Ile
M0210908 MICANLAO_00003 879 4 Gut 0.44 protein_coding upstream_gene_variant MODIFIER -9A>G None
M0210909 MICANLAO_00003 1138 7 Gut 0.78 protein_coding missense_variant MODERATE 251G>A Arg84Gln
M0210910 MICANLAO_00003 1245 4 Gut 0.44 protein_coding missense_variant MODERATE 358G>A Asp120Asn
M0210911 MICANLAO_00003 1426 6 Gut 0.67 protein_coding missense_variant MODERATE 539G>A Gly180Glu
M0210912 MICANLAO_00003 1644 5 Gut 0.56 protein_coding missense_variant MODERATE 757A>G Lys253Glu
M0210913 MICANLAO_00003 1662 5 Gut 0.56 protein_coding synonymous_variant LOW 775T>C Leu259Leu
M0210914 MICANLAO_00003 1871 4 Gut 0.44 protein_coding synonymous_variant LOW 984C>T Pro328Pro
M0210915 MICANLAO_00003 1895 4 Gut 0.44 protein_coding synonymous_variant LOW 1008G>A Arg336Arg
M0210916 MICANLAO_00003 2052 4 Gut 0.44 protein_coding missense_variant MODERATE 1165G>A Gly389Arg
M0210917 MICANLAO_00003 2053 4 Gut 0.44 protein_coding missense_variant MODERATE 1166G>A Gly389Glu
M0210918 MICANLAO_00003 2108 4 Gut 0.44 protein_coding synonymous_variant LOW 1221C>T Leu407Leu
M0210919 MICANLAO_00003 2153 4 Gut 0.44 protein_coding missense_variant MODERATE 1266G>A Met422Ile
M0210920 MICANLAO_00003 2393 4 Gut 0.44 protein_coding synonymous_variant LOW 1506A>G Val502Val
M0210921 MICANLAO_00003 2415 4 Gut 0.44 protein_coding synonymous_variant LOW 1528T>C Leu510Leu
M0210922 MICANLAO_00003 2420 4 Gut 0.44 protein_coding synonymous_variant LOW 1533G>A Ala511Ala
M0210923 MICANLAO_00001 2522 4 Gut 0.44 protein_coding downstream_gene_variant MODIFIER *2064C>T None
M0210924 MICANLAO_00001 2534 4 Gut 0.44 protein_coding downstream_gene_variant MODIFIER *2076G>A None
M0210925 MICANLAO_00001 2555 4 Gut 0.44 protein_coding downstream_gene_variant MODIFIER *2097T>C None
M0210926 MICANLAO_00001 2561 4 Gut 0.44 protein_coding downstream_gene_variant MODIFIER *2103G>A None
M0210927 MICANLAO_00001 2566 4 Gut 0.44 protein_coding downstream_gene_variant MODIFIER *2108T>C None
M0210928 MICANLAO_00001 2571 4 Gut 0.44 protein_coding downstream_gene_variant MODIFIER *2113T>C None
M0210929 MICANLAO_00001 2591 4 Gut 0.44 protein_coding downstream_gene_variant MODIFIER *2133T>C None
M0210930 MICANLAO_00001 2593 4 Gut 0.44 protein_coding downstream_gene_variant MODIFIER *2135C>T None
M0210931 MICANLAO_00001 2596 4 Gut 0.44 protein_coding downstream_gene_variant MODIFIER *2138C>A None
M0210932 MICANLAO_00001 2598 4 Gut 0.44 protein_coding downstream_gene_variant MODIFIER *2140G>A None
M0210933 MICANLAO_00001 2610 4 Gut 0.44 protein_coding downstream_gene_variant MODIFIER *2152G>A None
M0210934 MICANLAO_00002 477 3 Gut 0.33 protein_coding synonymous_variant LOW 36A>G Leu12Leu
M0210935 MICANLAO_00002 567 3 Gut 0.33 protein_coding missense_variant MODERATE 126C>G Asp42Glu
M0210936 MICANLAO_00002 642 3 Gut 0.33 protein_coding synonymous_variant LOW 201C>T Tyr67Tyr
M0210937 MICANLAO_00002 685 3 Gut 0.33 protein_coding missense_variant MODERATE 244G>A Asp82Asn
M0210938 MICANLAO_00003 846 3 Gut 0.33 protein_coding upstream_gene_variant MODIFIER -42A>G None
M0210939 MICANLAO_00003 848 3 Gut 0.33 protein_coding upstream_gene_variant MODIFIER -40A>T None
M0210940 MICANLAO_00003 850 3 Gut 0.33 protein_coding upstream_gene_variant MODIFIER -38C>T None
M0210941 MICANLAO_00003 855 3 Gut 0.33 protein_coding upstream_gene_variant MODIFIER -33C>G None
M0210942 MICANLAO_00003 943 5 Gut 0.56 protein_coding missense_variant MODERATE 56A>T Gln19Leu
M0210943 MICANLAO_00003 1092 3 Gut 0.33 protein_coding missense_variant MODERATE 205G>T Asp69Tyr






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term