Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1441
  Reference Plasmid   NZ_OY754365.1
  Reference Plasmid Size   126554
  Reference Plasmid GC Content   0.47
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0210979 MAOILOPM_00009 5711 3 Gut 0.43 protein_coding missense_variant MODERATE 272T>G Leu91Arg
M0210980 MAOILOPM_00009 5758 3 Gut 0.43 protein_coding missense_variant MODERATE 319G>A Ala107Thr
M0210981 MAOILOPM_00009 5782 5 Gut 0.71 protein_coding synonymous_variant LOW 343T>C Leu115Leu
M0210982 MAOILOPM_00013 7908 5 Gut 0.71 protein_coding synonymous_variant LOW 315T>C Thr105Thr
M0210983 MAOILOPM_00013 8401 5 Gut 0.71 protein_coding missense_variant MODERATE 808A>G Thr270Ala
M0210984 MAOILOPM_00014 8814 3 Gut 0.43 protein_coding missense_variant MODERATE 44A>G Glu15Gly
M0210985 MAOILOPM_00015 10684 5 Gut 0.71 protein_coding synonymous_variant LOW 936A>T Gly312Gly
M0210986 MAOILOPM_00012 11983 5 Gut 0.71 protein_coding upstream_gene_variant MODIFIER -4569A>G None
M0210987 MAOILOPM_00012 11992 5 Gut 0.71 protein_coding upstream_gene_variant MODIFIER -4578G>T None
M0210988 MAOILOPM_00012 12027 5 Gut 0.71 protein_coding upstream_gene_variant MODIFIER -4613C>T None
M0210989 MAOILOPM_00018 13930 3 Gut 0.43 protein_coding upstream_gene_variant MODIFIER -25T>C None
M0210990 MAOILOPM_00018 14895 3 Gut 0.43 protein_coding missense_variant MODERATE 941G>C Gly314Ala
M0210991 MAOILOPM_00018 15056 3 Gut 0.43 protein_coding missense_variant MODERATE 1102T>A Tyr368Asn
M0210992 MAOILOPM_00019 15553 3 Gut 0.43 protein_coding upstream_gene_variant MODIFIER -1A>T None
M0210993 MAOILOPM_00019 15836 5 Gut 0.71 protein_coding stop_lost&splice_region_variant HIGH 283T>C Ter95Glnext*?






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition
MAOILOPM_00057 VFG036043 AatA, AIDA-I type 96.7 0 1 1171 1.0 1.0052 Adherence autotransporter outer membrane beta-barrel domain-containing protein prediction







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism
MAOILOPM_00097 ARO:3000873 100 5.12e-208 1 286 1.0000 1.0000 monobactam TEM beta-lactamase antibiotic inactivation






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant
MAOILOPM_00028 PHI:3165 hopA1 72.4 3.2e-28 1 76 1.0000 0.9932 eudicots leaf spot (celery); leaf spot (eggplant); leaf spot (sweet pepper); wilt rot (muskmelon); stem rot (muskmelon); stem rot (chrysanthemum); leaf spot (soybean) effector (plant avirulence determinant) effector (plant avirulence determinant)
MAOILOPM_00037 PHI:3165 hopA1 72.4 7e-28 1 76 1.0000 0.9932 eudicots leaf spot (celery); leaf spot (eggplant); leaf spot (sweet pepper); wilt rot (muskmelon); stem rot (muskmelon); stem rot (chrysanthemum); leaf spot (soybean) effector (plant avirulence determinant) effector (plant avirulence determinant)
MAOILOPM_00041 PHI:3165 hopA1 73.7 8.3e-29 1 76 1.0000 0.9932 eudicots leaf spot (celery); leaf spot (eggplant); leaf spot (sweet pepper); wilt rot (muskmelon); stem rot (muskmelon); stem rot (chrysanthemum); leaf spot (soybean) effector (plant avirulence determinant) effector (plant avirulence determinant)
MAOILOPM_00109 PHI:3317 hsdR 73.2 0 1 1038 1.0000 1.0000 rodents Glasser's disease involved in pathogenicity reduced virulence
MAOILOPM_00131 PHI:10179 tnpA 74.3 1.3e-57 49 188 0.6829 0.9211 rodents salmonellosis regulatory RNA/ transposase for IS200 reduced virulence






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
MAOILOPM_00064 AYL89119.1|GH24 95.8 0 255 757 0.6645 0.9031
MAOILOPM_00134 AWJ02767.1|GT2 100 0 1 701 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
MAOILOPM_00130 1.B.55.3.1 95.9 0 1 1156 0.9991 0.9991 1 Channels/Pores 1.B β-Barrel Porins 1.B.55 The Poly Acetyl Glucosamine Porin (PgaA) Family