Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1453
  Reference Plasmid   NZ_PP589743.1
  Reference Plasmid Size   58107
  Reference Plasmid GC Content   0.35
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0211066 GLGMGOND_00050 48671 5 Gut 1.00 protein_coding synonymous_variant LOW 960T>C Gly320Gly
M0211067 GLGMGOND_00050 48686 5 Gut 1.00 protein_coding synonymous_variant LOW 945C>T Ile315Ile
M0211068 GLGMGOND_00050 48761 5 Gut 1.00 protein_coding synonymous_variant LOW 870T>C Ile290Ile
M0211069 GLGMGOND_00050 48764 5 Gut 1.00 protein_coding synonymous_variant LOW 867A>G Val289Val
M0211070 GLGMGOND_00050 48818 5 Gut 1.00 protein_coding synonymous_variant LOW 813A>G Pro271Pro
M0211071 GLGMGOND_00050 48836 5 Gut 1.00 protein_coding synonymous_variant LOW 795C>T Ser265Ser
M0211072 GLGMGOND_00050 48895 5 Gut 1.00 protein_coding missense_variant MODERATE 736A>G Thr246Ala
M0211073 GLGMGOND_00050 48902 5 Gut 1.00 protein_coding synonymous_variant LOW 729A>G Thr243Thr
M0211074 GLGMGOND_00050 48989 5 Gut 1.00 protein_coding synonymous_variant LOW 642A>T Ile214Ile
M0211075 GLGMGOND_00050 48994 5 Gut 1.00 protein_coding missense_variant MODERATE 637A>G Lys213Glu
M0211076 GLGMGOND_00050 49007 5 Gut 1.00 protein_coding synonymous_variant LOW 624C>G Pro208Pro
M0211077 GLGMGOND_00050 49031 5 Gut 1.00 protein_coding synonymous_variant LOW 600A>C Gly200Gly
M0211078 GLGMGOND_00050 49046 5 Gut 1.00 protein_coding synonymous_variant LOW 585A>G Thr195Thr
M0211079 GLGMGOND_00050 49049 5 Gut 1.00 protein_coding synonymous_variant LOW 582C>T Phe194Phe
M0211080 GLGMGOND_00050 49054 5 Gut 1.00 protein_coding missense_variant MODERATE 577T>C Ser193Pro
M0211081 GLGMGOND_00050 49055 5 Gut 1.00 protein_coding synonymous_variant LOW 576C>T His192His
M0211082 GLGMGOND_00050 49058 5 Gut 1.00 protein_coding synonymous_variant LOW 573G>A Glu191Glu
M0211083 GLGMGOND_00050 49061 5 Gut 1.00 protein_coding synonymous_variant LOW 570A>T Val190Val
M0211084 GLGMGOND_00050 49064 5 Gut 1.00 protein_coding synonymous_variant LOW 567A>G Lys189Lys
M0211085 GLGMGOND_00050 49070 5 Gut 1.00 protein_coding synonymous_variant LOW 561G>A Thr187Thr
M0211086 GLGMGOND_00050 49106 5 Gut 1.00 protein_coding synonymous_variant LOW 525C>T Ile175Ile
M0211087 GLGMGOND_00050 49112 5 Gut 1.00 protein_coding synonymous_variant LOW 519T>C Asn173Asn
M0211088 GLGMGOND_00050 49115 5 Gut 1.00 protein_coding synonymous_variant LOW 516C>T Asn172Asn
M0211089 GLGMGOND_00050 49118 5 Gut 1.00 protein_coding synonymous_variant LOW 513G>A Val171Val
M0211090 GLGMGOND_00050 49131 5 Gut 1.00 protein_coding missense_variant MODERATE 500G>A Arg167His
M0211091 GLGMGOND_00050 49133 5 Gut 1.00 protein_coding synonymous_variant LOW 498G>A Arg166Arg
M0211092 GLGMGOND_00050 49134 5 Gut 1.00 protein_coding missense_variant MODERATE 497G>A Arg166Lys
M0211093 GLGMGOND_00050 49136 5 Gut 1.00 protein_coding synonymous_variant LOW 495T>C Thr165Thr
M0211094 GLGMGOND_00050 49147 5 Gut 1.00 protein_coding synonymous_variant LOW 484T>C Leu162Leu
M0211095 GLGMGOND_00050 49148 5 Gut 1.00 protein_coding synonymous_variant LOW 483T>C Ser161Ser
M0211096 GLGMGOND_00050 49235 5 Gut 1.00 protein_coding missense_variant MODERATE 396C>G Asn132Lys
M0211097 GLGMGOND_00050 49348 5 Gut 1.00 protein_coding missense_variant MODERATE 283A>C Ile95Leu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition
GLGMGOND_00027 VFG005844 Capsule 98.5 1.9e-245 1 471 1.0 1 Immune modulation polysaccharide biosynthesis C-terminal domain-containing protein prediction







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
GLGMGOND_00017 QRZ28687.1|CBM5|GH18 98.2 0 1 508 1 1
GLGMGOND_00018 UOB69200.1|GT2 98.9 0 6 758 0.9934 1
GLGMGOND_00037 USI64453.1|GT2 99.7 1.36e-238 1 331 1 1
GLGMGOND_00045 USI64464.1|GT0 100 1.31e-220 1 281 1 0.9065
GLGMGOND_00046 ARE22184.1|GT4 100 8.99e-273 1 379 1 0.9974
GLGMGOND_00048 ARE22186.1|GT2 100 2.36e-209 1 285 1 1
GLGMGOND_00049 ARE22187.1|GT2 99.6 3.23e-209 1 280 1 1
GLGMGOND_00050 ARE22188.1|GT4 99.4 5.98e-265 1 360 0.9945 0.989





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
GLGMGOND_00027 2.A.66.2.16 97.7 8.3e-244 1 471 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.66 The Multidrug/Oligosaccharidyl-lipid/Polysaccharide (MOP) Flippase Superfamily