Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1455
  Reference Plasmid   OQ553951.1
  Reference Plasmid Size   44310
  Reference Plasmid GC Content   0.28
  Reference Plasmid Mobility Type   conjugative





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0211098 AIJOJHBD_00002 3321 4 Gut 1.00 protein_coding synonymous_variant LOW 1185G>A Thr395Thr
M0211099 AIJOJHBD_00004 4997 4 Gut 1.00 protein_coding missense_variant MODERATE 883T>C Cys295Arg
M0211100 AIJOJHBD_00004 4998 4 Gut 1.00 protein_coding missense_variant MODERATE 884G>A Cys295Tyr
M0211101 AIJOJHBD_00004 5150 4 Gut 1.00 protein_coding missense_variant MODERATE 1036A>C Ile346Leu
M0211102 AIJOJHBD_00004 5225 4 Gut 1.00 protein_coding missense_variant MODERATE 1111T>G Cys371Gly
M0211103 AIJOJHBD_00004 5898 4 Gut 1.00 protein_coding missense_variant MODERATE 1784A>G Tyr595Cys
M0211104 AIJOJHBD_00014 16290 4 Gut 1.00 protein_coding missense_variant MODERATE 1003A>G Ile335Val
M0211105 AIJOJHBD_00014 16341 4 Gut 1.00 protein_coding missense_variant MODERATE 952G>A Glu318Lys
M0211106 AIJOJHBD_00014 16405 4 Gut 1.00 protein_coding synonymous_variant LOW 888A>G Arg296Arg
M0211107 AIJOJHBD_00014 16504 4 Gut 1.00 protein_coding synonymous_variant LOW 789T>C Asn263Asn
M0211108 AIJOJHBD_00014 16516 4 Gut 1.00 protein_coding synonymous_variant LOW 777T>C Phe259Phe
M0211109 AIJOJHBD_00014 16527 4 Gut 1.00 protein_coding missense_variant MODERATE 766A>G Ile256Val
M0211110 AIJOJHBD_00014 16528 4 Gut 1.00 protein_coding synonymous_variant LOW 765G>A Gln255Gln
M0211111 AIJOJHBD_00023 21873 4 Gut 1.00 protein_coding missense_variant MODERATE 157G>A Gly53Arg
M0211112 AIJOJHBD_00023 22018 4 Gut 1.00 protein_coding synonymous_variant LOW 12G>A Lys4Lys
M0211113 AIJOJHBD_00044 36917 4 Gut 1.00 protein_coding missense_variant MODERATE 430A>G Thr144Ala






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism
AIJOJHBD_00004 ARO:3000190 99.7 0 1 639 1.0000 1.0000 tetracycline antibiotic tetracycline-resistant ribosomal protection protein antibiotic target protection






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term