Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1461
  Reference Plasmid   OY725836.1
  Reference Plasmid Size   154591
  Reference Plasmid GC Content   0.58
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0211149 DJOEAEGK_00131 143982 4 Gut 0.11 protein_coding upstream_gene_variant MODIFIER -2628G>C None
M0211150 DJOEAEGK_00134 144047 11 Gut 0.29 protein_coding synonymous_variant LOW 585T>G Val195Val
M0211151 DJOEAEGK_00134 144419 9 Gut 0.24 protein_coding synonymous_variant LOW 213C>T Leu71Leu
M0211152 DJOEAEGK_00134 144536 9 Gut 0.24 protein_coding synonymous_variant LOW 96C>T Tyr32Tyr
M0211153 DJOEAEGK_00134 144580 9 Gut 0.24 protein_coding missense_variant MODERATE 52A>G Met18Val
M0211154 DJOEAEGK_00134 144581 9 Gut 0.24 protein_coding synonymous_variant LOW 51A>G Ser17Ser
M0211155 DJOEAEGK_00134 144604 8 Gut 0.21 protein_coding missense_variant MODERATE 28T>G Leu10Val
M0211156 DJOEAEGK_00135 144679 7 Gut 0.18 protein_coding synonymous_variant LOW 801G>A Ala267Ala
M0211157 DJOEAEGK_00135 144835 7 Gut 0.18 protein_coding synonymous_variant LOW 645G>A Ala215Ala
M0211158 DJOEAEGK_00135 144869 7 Gut 0.18 protein_coding missense_variant MODERATE 611A>G Gln204Arg
M0211159 DJOEAEGK_00135 145402 14 Gut 0.37 protein_coding synonymous_variant LOW 78A>G Ala26Ala
M0211160 DJOEAEGK_00135 145420 14 Gut 0.37 protein_coding synonymous_variant LOW 60T>C Asp20Asp
M0211161 DJOEAEGK_00136 145665 16 Gut 0.42 protein_coding synonymous_variant LOW 66T>C Ile22Ile
M0211162 DJOEAEGK_00131 145800 12 Gut 0.32 protein_coding upstream_gene_variant MODIFIER -4446C>T None
M0211163 DJOEAEGK_00131 145814 13 Gut 0.34 protein_coding upstream_gene_variant MODIFIER -4460G>A None
M0211164 DJOEAEGK_00131 145818 13 Gut 0.34 protein_coding upstream_gene_variant MODIFIER -4464G>A None
M0211165 DJOEAEGK_00132 146374 12 Gut 0.32 protein_coding upstream_gene_variant MODIFIER -3602T>C None
M0211166 DJOEAEGK_00138 146761 11 Gut 0.29 protein_coding missense_variant MODERATE 316A>G Asn106Asp
M0211167 DJOEAEGK_00053 57799 3 Gut 0.08 protein_coding synonymous_variant LOW 1674T>C Gly558Gly
M0211168 DJOEAEGK_00053 57920 4 Gut 0.11 protein_coding missense_variant MODERATE 1553T>G Leu518Arg
M0211169 DJOEAEGK_00053 58495 3 Gut 0.08 protein_coding synonymous_variant LOW 978A>G Ala326Ala
M0211170 DJOEAEGK_00053 58518 3 Gut 0.08 protein_coding missense_variant MODERATE 955A>G Thr319Ala
M0211171 DJOEAEGK_00053 58534 3 Gut 0.08 protein_coding synonymous_variant LOW 939G>A Glu313Glu
M0211172 DJOEAEGK_00053 59035 6 Gut 0.16 protein_coding synonymous_variant LOW 438C>T Arg146Arg
M0211173 DJOEAEGK_00053 59351 4 Gut 0.11 protein_coding missense_variant MODERATE 122A>G His41Arg
M0211174 DJOEAEGK_00054 59845 6 Gut 0.16 protein_coding synonymous_variant LOW 426A>C Ile142Ile
M0211175 DJOEAEGK_00054 60087 6 Gut 0.16 protein_coding missense_variant MODERATE 184T>G Ser62Ala
M0211176 DJOEAEGK_00054 60184 6 Gut 0.16 protein_coding synonymous_variant LOW 87C>T Ala29Ala
M0211177 DJOEAEGK_00054 60193 6 Gut 0.16 protein_coding synonymous_variant LOW 78A>G Ala26Ala
M0211178 DJOEAEGK_00054 60220 6 Gut 0.16 protein_coding synonymous_variant LOW 51T>C Thr17Thr
M0211179 DJOEAEGK_00055 60360 6 Gut 0.16 protein_coding synonymous_variant LOW 1104C>A Ala368Ala
M0211180 DJOEAEGK_00055 60672 3 Gut 0.08 protein_coding synonymous_variant LOW 792C>T Ala264Ala
M0211181 DJOEAEGK_00055 60675 3 Gut 0.08 protein_coding synonymous_variant LOW 789T>G Leu263Leu
M0211182 DJOEAEGK_00056 62231 4 Gut 0.11 protein_coding synonymous_variant LOW 93G>A Leu31Leu
M0211183 DJOEAEGK_00056 62248 5 Gut 0.13 protein_coding synonymous_variant LOW 76T>C Leu26Leu
M0211184 DJOEAEGK_00057 63149 3 Gut 0.08 protein_coding synonymous_variant LOW 288T>C Pro96Pro
M0211185 DJOEAEGK_00057 63177 3 Gut 0.08 protein_coding missense_variant MODERATE 260C>T Ala87Val
M0211186 DJOEAEGK_00058 63631 5 Gut 0.13 protein_coding synonymous_variant LOW 921T>A Ala307Ala
M0211187 DJOEAEGK_00058 64249 4 Gut 0.11 protein_coding synonymous_variant LOW 303A>G Gly101Gly
M0211188 DJOEAEGK_00058 64474 6 Gut 0.16 protein_coding synonymous_variant LOW 78T>C Arg26Arg
M0211189 DJOEAEGK_00131 145866 10 Gut 0.26 protein_coding upstream_gene_variant MODIFIER -4512C>G None
M0211190 DJOEAEGK_00132 146423 5 Gut 0.13 protein_coding upstream_gene_variant MODIFIER -3651A>G None
M0211191 DJOEAEGK_00138 146926 10 Gut 0.26 protein_coding missense_variant MODERATE 151A>G Thr51Ala
M0211192 DJOEAEGK_00138 146938 5 Gut 0.13 protein_coding missense_variant MODERATE 139G>A Glu47Lys
M0211193 DJOEAEGK_00132 142638 5 Gut 0.13 protein_coding synonymous_variant LOW 135A>G Ala45Ala
M0211194 DJOEAEGK_00134 144335 3 Gut 0.08 protein_coding synonymous_variant LOW 297T>C Arg99Arg
M0211195 DJOEAEGK_00132 147107 7 Gut 0.18 protein_coding upstream_gene_variant MODIFIER -4335T>C None
M0211196 DJOEAEGK_00132 147125 8 Gut 0.21 protein_coding upstream_gene_variant MODIFIER -4353C>T None
M0211197 DJOEAEGK_00054 64645 3 Gut 0.08 protein_coding upstream_gene_variant MODIFIER -4375C>T None
M0211198 DJOEAEGK_00134 144200 5 Gut 0.13 protein_coding synonymous_variant LOW 432C>T Phe144Phe
M0211199 DJOEAEGK_00135 145363 6 Gut 0.16 protein_coding synonymous_variant LOW 117T>C Ala39Ala
M0211200 DJOEAEGK_00136 145548 5 Gut 0.13 protein_coding synonymous_variant LOW 183C>T Phe61Phe
M0211201 DJOEAEGK_00015 14694 4 Gut 0.11 protein_coding synonymous_variant LOW 1014A>G Lys338Lys
M0211202 DJOEAEGK_00016 14723 5 Gut 0.13 protein_coding upstream_gene_variant MODIFIER -101A>G None
M0211203 DJOEAEGK_00016 15093 5 Gut 0.13 protein_coding synonymous_variant LOW 270G>A Gly90Gly
M0211204 DJOEAEGK_00016 15484 5 Gut 0.13 protein_coding missense_variant MODERATE 661A>C Met221Leu
M0211205 DJOEAEGK_00016 15768 4 Gut 0.11 protein_coding synonymous_variant LOW 945G>A Val315Val
M0211206 DJOEAEGK_00093 100180 4 Gut 0.11 protein_coding missense_variant MODERATE 1261A>G Thr421Ala
M0211207 DJOEAEGK_00135 144633 3 Gut 0.08 protein_coding synonymous_variant LOW 847C>T Leu283Leu
M0211208 DJOEAEGK_00054 59605 5 Gut 0.13 protein_coding synonymous_variant LOW 666T>C Asp222Asp
M0211209 DJOEAEGK_00054 59611 4 Gut 0.11 protein_coding synonymous_variant LOW 660A>G Val220Val
M0211210 DJOEAEGK_00054 60022 3 Gut 0.08 protein_coding synonymous_variant LOW 249G>A Ala83Ala
M0211211 DJOEAEGK_00054 60091 3 Gut 0.08 protein_coding synonymous_variant LOW 180T>C Leu60Leu
M0211212 DJOEAEGK_00132 142025 3 Gut 0.08 protein_coding synonymous_variant LOW 748C>T Leu250Leu
M0211213 DJOEAEGK_00132 142388 3 Gut 0.08 protein_coding synonymous_variant LOW 385C>T Leu129Leu
M0211214 DJOEAEGK_00132 142446 3 Gut 0.08 protein_coding synonymous_variant LOW 327G>T Val109Val
M0211215 DJOEAEGK_00132 142506 3 Gut 0.08 protein_coding synonymous_variant LOW 267G>A Leu89Leu
M0211216 DJOEAEGK_00132 142749 3 Gut 0.08 protein_coding synonymous_variant LOW 24A>G Gln8Gln
M0211217 DJOEAEGK_00131 142846 3 Gut 0.08 protein_coding upstream_gene_variant MODIFIER -1492T>C None
M0211218 DJOEAEGK_00131 142848 3 Gut 0.08 protein_coding upstream_gene_variant MODIFIER -1494C>T None
M0211219 DJOEAEGK_00131 142850 3 Gut 0.08 protein_coding upstream_gene_variant MODIFIER -1496C>T None
M0211220 DJOEAEGK_00138 146839 3 Gut 0.08 protein_coding missense_variant MODERATE 238G>T Val80Phe
M0211221 DJOEAEGK_00016 15792 3 Gut 0.08 protein_coding synonymous_variant LOW 969G>A Thr323Thr
M0211222 DJOEAEGK_00053 59170 3 Gut 0.08 protein_coding synonymous_variant LOW 303T>C Asn101Asn
M0211223 DJOEAEGK_00053 59199 3 Gut 0.08 protein_coding missense_variant MODERATE 274A>G Thr92Ala
M0211224 DJOEAEGK_00053 59200 3 Gut 0.08 protein_coding synonymous_variant LOW 273A>G Thr91Thr
M0211225 DJOEAEGK_00014 13441 3 Gut 0.08 protein_coding missense_variant MODERATE 158C>T Ala53Val
M0211226 DJOEAEGK_00014 13525 3 Gut 0.08 protein_coding missense_variant MODERATE 242T>C Ile81Thr
M0211227 DJOEAEGK_00015 14038 3 Gut 0.08 protein_coding synonymous_variant LOW 358C>T Leu120Leu
M0211228 DJOEAEGK_00015 14097 3 Gut 0.08 protein_coding synonymous_variant LOW 417C>T Ser139Ser
M0211229 DJOEAEGK_00015 14098 3 Gut 0.08 protein_coding synonymous_variant LOW 418C>T Leu140Leu
M0211230 DJOEAEGK_00015 14496 3 Gut 0.08 protein_coding synonymous_variant LOW 816C>T Ile272Ile
M0211231 DJOEAEGK_00015 14538 3 Gut 0.08 protein_coding synonymous_variant LOW 858C>T Ser286Ser
M0211232 DJOEAEGK_00016 14735 3 Gut 0.08 protein_coding upstream_gene_variant MODIFIER -89T>G None
M0211233 DJOEAEGK_00016 14893 3 Gut 0.08 protein_coding synonymous_variant LOW 70C>T Leu24Leu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term