Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1463
  Reference Plasmid   OY725838.1
  Reference Plasmid Size   109843
  Reference Plasmid GC Content   0.56
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0211238 HGJFIHPA_00013 17316 4 Gut 0.24 protein_coding synonymous_variant LOW 75T>C Phe25Phe
M0211239 HGJFIHPA_00013 17365 9 Gut 0.53 protein_coding missense_variant MODERATE 124A>G Met42Val
M0211240 HGJFIHPA_00013 17438 10 Gut 0.59 protein_coding missense_variant MODERATE 197C>A Thr66Asn
M0211241 HGJFIHPA_00013 17538 11 Gut 0.65 protein_coding synonymous_variant LOW 297G>T Pro99Pro
M0211242 HGJFIHPA_00013 17568 4 Gut 0.24 protein_coding synonymous_variant LOW 327T>C Ser109Ser
M0211243 HGJFIHPA_00013 17680 12 Gut 0.71 protein_coding synonymous_variant LOW 439T>C Leu147Leu
M0211244 HGJFIHPA_00013 17709 3 Gut 0.18 protein_coding synonymous_variant LOW 468C>A Gly156Gly
M0211245 HGJFIHPA_00013 17733 6 Gut 0.35 protein_coding synonymous_variant LOW 492T>C Asp164Asp
M0211246 HGJFIHPA_00013 17769 12 Gut 0.71 protein_coding synonymous_variant LOW 528T>C Asp176Asp
M0211247 HGJFIHPA_00013 17787 10 Gut 0.59 protein_coding synonymous_variant LOW 546A>G Ala182Ala
M0211248 HGJFIHPA_00013 17832 5 Gut 0.29 protein_coding synonymous_variant LOW 591C>T Asp197Asp
M0211249 HGJFIHPA_00013 17850 8 Gut 0.47 protein_coding synonymous_variant LOW 609G>T Val203Val
M0211250 HGJFIHPA_00013 17859 9 Gut 0.53 protein_coding synonymous_variant LOW 618C>T Asp206Asp
M0211251 HGJFIHPA_00013 17898 12 Gut 0.71 protein_coding synonymous_variant LOW 657A>G Val219Val
M0211252 HGJFIHPA_00013 18047 12 Gut 0.71 protein_coding missense_variant MODERATE 806A>C Glu269Ala
M0211253 HGJFIHPA_00014 18099 12 Gut 0.71 protein_coding upstream_gene_variant MODIFIER -471G>A None
M0211254 HGJFIHPA_00014 18142 8 Gut 0.47 protein_coding upstream_gene_variant MODIFIER -428T>G None
M0211255 HGJFIHPA_00014 18144 12 Gut 0.71 protein_coding upstream_gene_variant MODIFIER -426T>G None
M0211256 HGJFIHPA_00014 18205 12 Gut 0.71 protein_coding upstream_gene_variant MODIFIER -365A>G None
M0211257 HGJFIHPA_00014 18294 5 Gut 0.29 protein_coding upstream_gene_variant MODIFIER -276A>C None
M0211258 HGJFIHPA_00014 18359 10 Gut 0.59 protein_coding upstream_gene_variant MODIFIER -211T>C None
M0211259 HGJFIHPA_00014 18560 11 Gut 0.65 protein_coding upstream_gene_variant MODIFIER -10T>G None
M0211260 HGJFIHPA_00014 18605 7 Gut 0.41 protein_coding synonymous_variant LOW 36G>A Ala12Ala
M0211261 HGJFIHPA_00014 18686 10 Gut 0.59 protein_coding synonymous_variant LOW 117G>A Glu39Glu
M0211262 HGJFIHPA_00014 18769 10 Gut 0.59 protein_coding missense_variant MODERATE 200A>G Lys67Arg
M0211263 HGJFIHPA_00014 18821 8 Gut 0.47 protein_coding synonymous_variant LOW 252G>A Thr84Thr
M0211264 HGJFIHPA_00014 18874 8 Gut 0.47 protein_coding missense_variant MODERATE 305A>G Glu102Gly
M0211265 HGJFIHPA_00014 18885 9 Gut 0.53 protein_coding missense_variant MODERATE 316A>G Thr106Ala
M0211266 HGJFIHPA_00014 18910 8 Gut 0.47 protein_coding missense_variant MODERATE 341C>A Ala114Asp
M0211267 HGJFIHPA_00014 18958 4 Gut 0.24 protein_coding missense_variant MODERATE 389C>T Ala130Val
M0211268 HGJFIHPA_00014 18977 9 Gut 0.53 protein_coding synonymous_variant LOW 408T>C Ser136Ser
M0211269 HGJFIHPA_00014 18999 8 Gut 0.47 protein_coding missense_variant MODERATE 430G>A Ala144Thr
M0211270 HGJFIHPA_00014 19027 8 Gut 0.47 protein_coding missense_variant MODERATE 458A>G Tyr153Cys
M0211271 HGJFIHPA_00013 17225 6 Gut 0.35 protein_coding upstream_gene_variant MODIFIER -17T>C None
M0211272 HGJFIHPA_00013 17317 4 Gut 0.24 protein_coding missense_variant MODERATE 76C>T Pro26Ser
M0211273 HGJFIHPA_00013 17382 3 Gut 0.18 protein_coding synonymous_variant LOW 141G>A Gly47Gly
M0211274 HGJFIHPA_00013 17504 4 Gut 0.24 protein_coding missense_variant MODERATE 263A>G His88Arg
M0211275 HGJFIHPA_00013 17512 3 Gut 0.18 protein_coding missense_variant MODERATE 271A>G Thr91Ala
M0211276 HGJFIHPA_00013 17562 10 Gut 0.59 protein_coding synonymous_variant LOW 321A>G Lys107Lys
M0211277 HGJFIHPA_00014 18233 5 Gut 0.29 protein_coding upstream_gene_variant MODIFIER -337A>G None
M0211278 HGJFIHPA_00014 18235 5 Gut 0.29 protein_coding upstream_gene_variant MODIFIER -335C>T None
M0211279 HGJFIHPA_00014 18362 8 Gut 0.47 protein_coding upstream_gene_variant MODIFIER -208C>T None
M0211280 HGJFIHPA_00014 18382 3 Gut 0.18 protein_coding upstream_gene_variant MODIFIER -188G>A None
M0211281 HGJFIHPA_00013 17080 4 Gut 0.24 protein_coding upstream_gene_variant MODIFIER -162C>A None
M0211282 HGJFIHPA_00013 17116 4 Gut 0.24 protein_coding upstream_gene_variant MODIFIER -126A>G None
M0211283 HGJFIHPA_00013 17129 4 Gut 0.24 protein_coding upstream_gene_variant MODIFIER -113A>G None
M0211284 HGJFIHPA_00013 17143 4 Gut 0.24 protein_coding upstream_gene_variant MODIFIER -99T>G None
M0211285 HGJFIHPA_00013 17158 4 Gut 0.24 protein_coding upstream_gene_variant MODIFIER -84C>T None
M0211286 HGJFIHPA_00013 17183 4 Gut 0.24 protein_coding upstream_gene_variant MODIFIER -59T>A None
M0211287 HGJFIHPA_00013 17820 3 Gut 0.18 protein_coding synonymous_variant LOW 579C>T Ile193Ile
M0211288 HGJFIHPA_00013 17689 3 Gut 0.18 protein_coding missense_variant MODERATE 448C>T His150Tyr
M0211289 HGJFIHPA_00013 17697 3 Gut 0.18 protein_coding synonymous_variant LOW 456C>T Asp152Asp






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
HGJFIHPA_00011 BCK83990.1|GH33 80.3 7.55e-236 1 385 1 0.9974





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term