Annotation Categories of the Plasmid Cluster
Summary of the plasmid cluster
Basic Information about the Plasmid Cluster
Cluster Information |
Plasmid Cluster ID |
C1470 |
Reference Plasmid |
OY725878.1 |
Reference Plasmid Size |
247546 |
Reference Plasmid GC Content |
0.50 |
Reference Plasmid Mobility Type |
non-mobilizable |
Mutation sites in the plasmid cluster
The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..
mutid |
gname |
pos |
count |
tissue |
frequnt |
biotype |
consequence |
impact |
nucchange |
aachange |
M0211982 |
IHOEBPKH_00065 |
73500 |
12 |
Gut |
0.16 |
protein_coding |
synonymous_variant |
LOW |
558C>T |
Gly186Gly |
M0211983 |
IHOEBPKH_00065 |
73503 |
8 |
Gut |
0.11 |
protein_coding |
synonymous_variant |
LOW |
561G>A |
Val187Val |
M0211984 |
IHOEBPKH_00065 |
73506 |
8 |
Gut |
0.11 |
protein_coding |
synonymous_variant |
LOW |
564C>T |
Ile188Ile |
M0211985 |
IHOEBPKH_00065 |
73551 |
8 |
Gut |
0.11 |
protein_coding |
synonymous_variant |
LOW |
609T>C |
Asp203Asp |
M0211986 |
IHOEBPKH_00065 |
73555 |
11 |
Gut |
0.15 |
protein_coding |
synonymous_variant |
LOW |
613T>C |
Leu205Leu |
M0211987 |
IHOEBPKH_00065 |
73578 |
11 |
Gut |
0.15 |
protein_coding |
synonymous_variant |
LOW |
636T>C |
Asp212Asp |
M0211988 |
IHOEBPKH_00065 |
73581 |
11 |
Gut |
0.15 |
protein_coding |
synonymous_variant |
LOW |
639C>T |
Ala213Ala |
M0211989 |
IHOEBPKH_00065 |
73584 |
13 |
Gut |
0.18 |
protein_coding |
synonymous_variant |
LOW |
642A>C |
Ile214Ile |
M0211990 |
IHOEBPKH_00066 |
74032 |
12 |
Gut |
0.16 |
protein_coding |
synonymous_variant |
LOW |
213G>A |
Pro71Pro |
M0211991 |
IHOEBPKH_00066 |
74044 |
23 |
Gut |
0.31 |
protein_coding |
synonymous_variant |
LOW |
225G>T |
Ser75Ser |
M0211992 |
IHOEBPKH_00066 |
74065 |
12 |
Gut |
0.16 |
protein_coding |
synonymous_variant |
LOW |
246G>A |
Val82Val |
M0211993 |
IHOEBPKH_00066 |
74068 |
24 |
Gut |
0.32 |
protein_coding |
synonymous_variant |
LOW |
249A>G |
Val83Val |
M0211994 |
IHOEBPKH_00066 |
74204 |
13 |
Gut |
0.18 |
protein_coding |
missense_variant |
MODERATE |
385C>T |
Pro129Ser |
M0211995 |
IHOEBPKH_00066 |
74230 |
12 |
Gut |
0.16 |
protein_coding |
missense_variant |
MODERATE |
411C>A |
Ser137Arg |
M0211996 |
IHOEBPKH_00066 |
74239 |
16 |
Gut |
0.22 |
protein_coding |
synonymous_variant |
LOW |
420C>T |
Ala140Ala |
M0211997 |
IHOEBPKH_00066 |
74240 |
16 |
Gut |
0.22 |
protein_coding |
missense_variant |
MODERATE |
421A>G |
Ser141Gly |
M0211998 |
IHOEBPKH_00066 |
74243 |
16 |
Gut |
0.22 |
protein_coding |
missense_variant |
MODERATE |
424A>G |
Thr142Ala |
M0211999 |
IHOEBPKH_00066 |
74245 |
16 |
Gut |
0.22 |
protein_coding |
synonymous_variant |
LOW |
426T>C |
Thr142Thr |
M0212000 |
IHOEBPKH_00066 |
74254 |
16 |
Gut |
0.22 |
protein_coding |
synonymous_variant |
LOW |
435G>A |
Ala145Ala |
M0212001 |
IHOEBPKH_00066 |
74264 |
19 |
Gut |
0.26 |
protein_coding |
synonymous_variant |
LOW |
445A>C |
Arg149Arg |
M0212002 |
IHOEBPKH_00068 |
74295 |
16 |
Gut |
0.22 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-464T>C |
None |
M0212003 |
IHOEBPKH_00067 |
74509 |
10 |
Gut |
0.14 |
protein_coding |
synonymous_variant |
LOW |
124C>T |
Leu42Leu |
M0212004 |
IHOEBPKH_00067 |
75903 |
5 |
Gut |
0.07 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-1271T>C |
None |
M0212005 |
IHOEBPKH_00067 |
76036 |
11 |
Gut |
0.15 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-1404C>A |
None |
M0212006 |
IHOEBPKH_00067 |
76052 |
11 |
Gut |
0.15 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-1420C>T |
None |
M0212007 |
IHOEBPKH_00067 |
76061 |
11 |
Gut |
0.15 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-1429C>T |
None |
M0212008 |
IHOEBPKH_00067 |
76063 |
11 |
Gut |
0.15 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-1431C>T |
None |
M0212009 |
IHOEBPKH_00069 |
76141 |
6 |
Gut |
0.08 |
protein_coding |
synonymous_variant |
LOW |
48A>G |
Arg16Arg |
M0212010 |
IHOEBPKH_00069 |
76156 |
6 |
Gut |
0.08 |
protein_coding |
synonymous_variant |
LOW |
63G>A |
Leu21Leu |
M0212011 |
IHOEBPKH_00069 |
76159 |
6 |
Gut |
0.08 |
protein_coding |
synonymous_variant |
LOW |
66G>T |
Val22Val |
M0212012 |
IHOEBPKH_00069 |
76195 |
10 |
Gut |
0.14 |
protein_coding |
synonymous_variant |
LOW |
102T>C |
Ile34Ile |
M0212013 |
IHOEBPKH_00069 |
76216 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
123C>T |
Ser41Ser |
M0212014 |
IHOEBPKH_00069 |
76227 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
134G>C |
Ser45Thr |
M0212015 |
IHOEBPKH_00069 |
76229 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
136T>G |
Ser46Ala |
M0212016 |
IHOEBPKH_00069 |
76230 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
137C>T |
Ser46Leu |
M0212017 |
IHOEBPKH_00069 |
76240 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
147T>C |
Val49Val |
M0212018 |
IHOEBPKH_00069 |
76243 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
150C>T |
Tyr50Tyr |
M0212019 |
IHOEBPKH_00069 |
76246 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
153A>G |
Glu51Glu |
M0212020 |
IHOEBPKH_00069 |
76255 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
162C>A |
Pro54Pro |
M0212021 |
IHOEBPKH_00069 |
76282 |
6 |
Gut |
0.08 |
protein_coding |
synonymous_variant |
LOW |
189G>A |
Lys63Lys |
M0212022 |
IHOEBPKH_00069 |
76306 |
6 |
Gut |
0.08 |
protein_coding |
synonymous_variant |
LOW |
213G>A |
Glu71Glu |
M0212023 |
IHOEBPKH_00069 |
76345 |
8 |
Gut |
0.11 |
protein_coding |
synonymous_variant |
LOW |
252G>A |
Glu84Glu |
M0212024 |
IHOEBPKH_00069 |
76396 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
303G>A |
Glu101Glu |
M0212025 |
IHOEBPKH_00069 |
76420 |
5 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
327T>G |
Leu109Leu |
M0212026 |
IHOEBPKH_00069 |
76429 |
5 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
336G>A |
Lys112Lys |
M0212027 |
IHOEBPKH_00069 |
76441 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
348A>G |
Ala116Ala |
M0212028 |
IHOEBPKH_00069 |
76450 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
357C>T |
Tyr119Tyr |
M0212029 |
IHOEBPKH_00064 |
72491 |
20 |
Gut |
0.27 |
protein_coding |
synonymous_variant |
LOW |
151T>C |
Leu51Leu |
M0212030 |
IHOEBPKH_00064 |
72571 |
24 |
Gut |
0.32 |
protein_coding |
synonymous_variant |
LOW |
231T>A |
Ala77Ala |
M0212031 |
IHOEBPKH_00065 |
72803 |
5 |
Gut |
0.07 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-140C>T |
None |
M0212032 |
IHOEBPKH_00065 |
72816 |
5 |
Gut |
0.07 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-127C>T |
None |
M0212033 |
IHOEBPKH_00065 |
72818 |
5 |
Gut |
0.07 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-125A>C |
None |
M0212034 |
IHOEBPKH_00065 |
72832 |
5 |
Gut |
0.07 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-111T>C |
None |
M0212035 |
IHOEBPKH_00065 |
72924 |
17 |
Gut |
0.23 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-19C>T |
None |
M0212036 |
IHOEBPKH_00065 |
73008 |
33 |
Gut |
0.45 |
protein_coding |
synonymous_variant |
LOW |
66T>C |
Ser22Ser |
M0212037 |
IHOEBPKH_00065 |
73123 |
31 |
Gut |
0.42 |
protein_coding |
missense_variant |
MODERATE |
181A>G |
Asn61Asp |
M0212038 |
IHOEBPKH_00065 |
73227 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
285G>A |
Pro95Pro |
M0212039 |
IHOEBPKH_00065 |
73317 |
20 |
Gut |
0.27 |
protein_coding |
synonymous_variant |
LOW |
375C>T |
Tyr125Tyr |
M0212040 |
IHOEBPKH_00065 |
73374 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
432C>T |
Thr144Thr |
M0212041 |
IHOEBPKH_00065 |
73675 |
11 |
Gut |
0.15 |
protein_coding |
synonymous_variant |
LOW |
733T>C |
Leu245Leu |
M0212042 |
IHOEBPKH_00066 |
74157 |
20 |
Gut |
0.27 |
protein_coding |
missense_variant |
MODERATE |
338T>C |
Leu113Pro |
M0212043 |
IHOEBPKH_00067 |
74480 |
13 |
Gut |
0.18 |
protein_coding |
synonymous_variant |
LOW |
153G>A |
Thr51Thr |
M0212044 |
IHOEBPKH_00067 |
74504 |
13 |
Gut |
0.18 |
protein_coding |
synonymous_variant |
LOW |
129T>G |
Gly43Gly |
M0212045 |
IHOEBPKH_00068 |
74956 |
11 |
Gut |
0.15 |
protein_coding |
synonymous_variant |
LOW |
198A>G |
Leu66Leu |
M0212046 |
IHOEBPKH_00068 |
75068 |
7 |
Gut |
0.09 |
protein_coding |
missense_variant |
MODERATE |
310T>C |
Cys104Arg |
M0212047 |
IHOEBPKH_00068 |
75199 |
5 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
441G>A |
Arg147Arg |
M0212048 |
IHOEBPKH_00067 |
75516 |
7 |
Gut |
0.09 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-884C>A |
None |
M0212049 |
IHOEBPKH_00067 |
75534 |
4 |
Gut |
0.05 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-902G>A |
None |
M0212050 |
IHOEBPKH_00067 |
75629 |
3 |
Gut |
0.04 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-997C>T |
None |
M0212051 |
IHOEBPKH_00062 |
71958 |
15 |
Gut |
0.20 |
protein_coding |
synonymous_variant |
LOW |
1956G>T |
Pro652Pro |
M0212052 |
IHOEBPKH_00064 |
72619 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
279G>A |
Val93Val |
M0212053 |
IHOEBPKH_00065 |
73206 |
26 |
Gut |
0.35 |
protein_coding |
synonymous_variant |
LOW |
264A>C |
Ile88Ile |
M0212054 |
IHOEBPKH_00065 |
73395 |
5 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
453A>G |
Glu151Glu |
M0212055 |
IHOEBPKH_00068 |
75026 |
11 |
Gut |
0.15 |
protein_coding |
missense_variant |
MODERATE |
268G>A |
Ala90Thr |
M0212056 |
IHOEBPKH_00065 |
73014 |
26 |
Gut |
0.35 |
protein_coding |
synonymous_variant |
LOW |
72T>G |
Leu24Leu |
M0212057 |
IHOEBPKH_00065 |
73104 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
162G>A |
Arg54Arg |
M0212058 |
IHOEBPKH_00065 |
73384 |
19 |
Gut |
0.26 |
protein_coding |
missense_variant |
MODERATE |
442G>A |
Ala148Thr |
M0212059 |
IHOEBPKH_00065 |
73728 |
13 |
Gut |
0.18 |
protein_coding |
synonymous_variant |
LOW |
786T>C |
Gly262Gly |
M0212060 |
IHOEBPKH_00065 |
73731 |
13 |
Gut |
0.18 |
protein_coding |
synonymous_variant |
LOW |
789C>T |
Gly263Gly |
M0212061 |
IHOEBPKH_00065 |
73777 |
7 |
Gut |
0.09 |
protein_coding |
missense_variant |
MODERATE |
835A>G |
Thr279Ala |
M0212062 |
IHOEBPKH_00066 |
73930 |
6 |
Gut |
0.08 |
protein_coding |
synonymous_variant |
LOW |
111T>G |
Thr37Thr |
M0212063 |
IHOEBPKH_00066 |
73948 |
8 |
Gut |
0.11 |
protein_coding |
synonymous_variant |
LOW |
129G>A |
Glu43Glu |
M0212064 |
IHOEBPKH_00066 |
73951 |
18 |
Gut |
0.24 |
protein_coding |
synonymous_variant |
LOW |
132A>G |
Leu44Leu |
M0212065 |
IHOEBPKH_00066 |
74020 |
11 |
Gut |
0.15 |
protein_coding |
synonymous_variant |
LOW |
201G>A |
Gln67Gln |
M0212066 |
IHOEBPKH_00066 |
74026 |
8 |
Gut |
0.11 |
protein_coding |
synonymous_variant |
LOW |
207G>A |
Pro69Pro |
M0212067 |
IHOEBPKH_00066 |
74047 |
12 |
Gut |
0.16 |
protein_coding |
synonymous_variant |
LOW |
228T>C |
Ile76Ile |
M0212068 |
IHOEBPKH_00066 |
74074 |
8 |
Gut |
0.11 |
protein_coding |
synonymous_variant |
LOW |
255C>T |
Ile85Ile |
M0212069 |
IHOEBPKH_00066 |
74180 |
11 |
Gut |
0.15 |
protein_coding |
missense_variant |
MODERATE |
361G>A |
Ala121Thr |
M0212070 |
IHOEBPKH_00066 |
74248 |
12 |
Gut |
0.16 |
protein_coding |
synonymous_variant |
LOW |
429G>A |
Leu143Leu |
M0212071 |
IHOEBPKH_00067 |
74372 |
14 |
Gut |
0.19 |
protein_coding |
synonymous_variant |
LOW |
261A>G |
Thr87Thr |
M0212072 |
IHOEBPKH_00067 |
74392 |
11 |
Gut |
0.15 |
protein_coding |
missense_variant |
MODERATE |
241G>A |
Glu81Lys |
M0212073 |
IHOEBPKH_00067 |
74402 |
11 |
Gut |
0.15 |
protein_coding |
synonymous_variant |
LOW |
231C>T |
Ser77Ser |
M0212074 |
IHOEBPKH_00067 |
74405 |
12 |
Gut |
0.16 |
protein_coding |
synonymous_variant |
LOW |
228C>T |
Ser76Ser |
M0212075 |
IHOEBPKH_00067 |
74413 |
11 |
Gut |
0.15 |
protein_coding |
missense_variant |
MODERATE |
220A>G |
Thr74Ala |
M0212076 |
IHOEBPKH_00067 |
74576 |
13 |
Gut |
0.18 |
protein_coding |
synonymous_variant |
LOW |
57A>G |
Leu19Leu |
M0212077 |
IHOEBPKH_00067 |
74585 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
48G>A |
Arg16Arg |
M0212078 |
IHOEBPKH_00067 |
74627 |
5 |
Gut |
0.07 |
protein_coding |
missense_variant |
MODERATE |
6A>T |
Glu2Asp |
M0212079 |
IHOEBPKH_00067 |
74711 |
11 |
Gut |
0.15 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-79G>A |
None |
M0212080 |
IHOEBPKH_00067 |
74739 |
11 |
Gut |
0.15 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-107G>A |
None |
M0212081 |
IHOEBPKH_00067 |
74741 |
11 |
Gut |
0.15 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-109G>T |
None |
M0212082 |
IHOEBPKH_00067 |
74743 |
11 |
Gut |
0.15 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-111T>C |
None |
M0212083 |
IHOEBPKH_00067 |
74755 |
11 |
Gut |
0.15 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-123A>G |
None |
M0212084 |
IHOEBPKH_00067 |
74756 |
11 |
Gut |
0.15 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-124A>G |
None |
M0212085 |
IHOEBPKH_00068 |
74788 |
11 |
Gut |
0.15 |
protein_coding |
synonymous_variant |
LOW |
30T>C |
Gly10Gly |
M0212086 |
IHOEBPKH_00068 |
74794 |
11 |
Gut |
0.15 |
protein_coding |
synonymous_variant |
LOW |
36A>G |
Arg12Arg |
M0212087 |
IHOEBPKH_00068 |
74881 |
7 |
Gut |
0.09 |
protein_coding |
synonymous_variant |
LOW |
123C>T |
Leu41Leu |
M0212088 |
IHOEBPKH_00068 |
74885 |
10 |
Gut |
0.14 |
protein_coding |
missense_variant |
MODERATE |
127C>A |
His43Asn |
M0212089 |
IHOEBPKH_00068 |
74887 |
11 |
Gut |
0.15 |
protein_coding |
synonymous_variant |
LOW |
129T>C |
His43His |
M0212090 |
IHOEBPKH_00164 |
165552 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
906G>A |
Val302Val |
M0212091 |
IHOEBPKH_00165 |
165593 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
6G>C |
Lys2Asn |
M0212092 |
IHOEBPKH_00165 |
165641 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
54T>C |
Ala18Ala |
M0212093 |
IHOEBPKH_00165 |
165737 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
150T>C |
Gly50Gly |
M0212094 |
IHOEBPKH_00165 |
165959 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
372T>C |
Val124Val |
M0212095 |
IHOEBPKH_00165 |
165968 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
381G>T |
Val127Val |
M0212096 |
IHOEBPKH_00165 |
166070 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
483C>T |
Asp161Asp |
M0212097 |
IHOEBPKH_00165 |
166103 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
516C>A |
Arg172Arg |
M0212098 |
IHOEBPKH_00165 |
166120 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
533G>A |
Gly178Asp |
M0212099 |
IHOEBPKH_00165 |
166238 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
651A>G |
Pro217Pro |
M0212100 |
IHOEBPKH_00165 |
166253 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
666T>G |
Arg222Arg |
M0212101 |
IHOEBPKH_00165 |
166268 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
681T>C |
Ile227Ile |
M0212102 |
IHOEBPKH_00166 |
166401 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
78T>C |
Phe26Phe |
M0212103 |
IHOEBPKH_00166 |
166683 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
360G>A |
Val120Val |
M0212104 |
IHOEBPKH_00166 |
166701 |
6 |
Gut |
0.08 |
protein_coding |
synonymous_variant |
LOW |
378C>T |
Asn126Asn |
M0212105 |
IHOEBPKH_00166 |
166791 |
6 |
Gut |
0.08 |
protein_coding |
synonymous_variant |
LOW |
468C>A |
Val156Val |
M0212106 |
IHOEBPKH_00166 |
166848 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
525A>G |
Lys175Lys |
M0212107 |
IHOEBPKH_00166 |
166890 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
567G>A |
Thr189Thr |
M0212108 |
IHOEBPKH_00166 |
166900 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
577C>T |
Leu193Leu |
M0212109 |
IHOEBPKH_00166 |
166977 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
654C>T |
Arg218Arg |
M0212110 |
IHOEBPKH_00166 |
167079 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
756T>C |
Tyr252Tyr |
M0212111 |
IHOEBPKH_00166 |
167082 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
759T>C |
Asn253Asn |
M0212112 |
IHOEBPKH_00168 |
167901 |
7 |
Gut |
0.09 |
protein_coding |
synonymous_variant |
LOW |
96T>C |
Gly32Gly |
M0212113 |
IHOEBPKH_00168 |
167922 |
7 |
Gut |
0.09 |
protein_coding |
synonymous_variant |
LOW |
117G>A |
Val39Val |
M0212114 |
IHOEBPKH_00168 |
167961 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
156T>C |
Ile52Ile |
M0212115 |
IHOEBPKH_00168 |
167965 |
7 |
Gut |
0.09 |
protein_coding |
missense_variant |
MODERATE |
160G>A |
Val54Met |
M0212116 |
IHOEBPKH_00168 |
168099 |
5 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
294G>A |
Val98Val |
M0212117 |
IHOEBPKH_00169 |
168143 |
5 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
15G>A |
Ser5Ser |
M0212118 |
IHOEBPKH_00169 |
168221 |
7 |
Gut |
0.09 |
protein_coding |
missense_variant |
MODERATE |
93C>G |
Ser31Arg |
M0212119 |
IHOEBPKH_00169 |
168248 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
120C>T |
Gly40Gly |
M0212120 |
IHOEBPKH_00169 |
168263 |
5 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
135C>T |
Ala45Ala |
M0212121 |
IHOEBPKH_00169 |
168272 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
144A>G |
Glu48Glu |
M0212122 |
IHOEBPKH_00169 |
168404 |
7 |
Gut |
0.09 |
protein_coding |
synonymous_variant |
LOW |
276A>G |
Gln92Gln |
M0212123 |
IHOEBPKH_00169 |
168407 |
7 |
Gut |
0.09 |
protein_coding |
synonymous_variant |
LOW |
279A>C |
Ser93Ser |
M0212124 |
IHOEBPKH_00169 |
168452 |
7 |
Gut |
0.09 |
protein_coding |
synonymous_variant |
LOW |
324T>A |
Gly108Gly |
M0212125 |
IHOEBPKH_00169 |
168471 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
343T>C |
Leu115Leu |
M0212126 |
IHOEBPKH_00169 |
168473 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
345A>G |
Leu115Leu |
M0212127 |
IHOEBPKH_00169 |
168485 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
357C>T |
Arg119Arg |
M0212128 |
IHOEBPKH_00169 |
168569 |
8 |
Gut |
0.11 |
protein_coding |
synonymous_variant |
LOW |
441C>T |
Gly147Gly |
M0212129 |
IHOEBPKH_00064 |
72760 |
11 |
Gut |
0.15 |
protein_coding |
synonymous_variant |
LOW |
420G>A |
Gln140Gln |
M0212130 |
IHOEBPKH_00062 |
70167 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
165G>T |
Thr55Thr |
M0212131 |
IHOEBPKH_00062 |
70600 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
598T>A |
Cys200Ser |
M0212132 |
IHOEBPKH_00062 |
70761 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
759A>T |
Ile253Ile |
M0212133 |
IHOEBPKH_00062 |
70764 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
762T>G |
Pro254Pro |
M0212134 |
IHOEBPKH_00062 |
70795 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
793T>C |
Leu265Leu |
M0212135 |
IHOEBPKH_00062 |
70887 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
885A>G |
Ala295Ala |
M0212136 |
IHOEBPKH_00062 |
70989 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
987A>G |
Val329Val |
M0212137 |
IHOEBPKH_00062 |
71104 |
4 |
Gut |
0.05 |
protein_coding |
missense_variant |
MODERATE |
1102T>C |
Ser368Pro |
M0212138 |
IHOEBPKH_00062 |
71106 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
1104T>G |
Ser368Ser |
M0212139 |
IHOEBPKH_00062 |
71265 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
1263A>C |
Leu421Phe |
M0212140 |
IHOEBPKH_00062 |
71274 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
1272A>G |
Arg424Arg |
M0212141 |
IHOEBPKH_00062 |
71284 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
1282A>G |
Ile428Val |
M0212142 |
IHOEBPKH_00062 |
71289 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
1287A>G |
Ala429Ala |
M0212143 |
IHOEBPKH_00062 |
71291 |
4 |
Gut |
0.05 |
protein_coding |
missense_variant |
MODERATE |
1289T>A |
Val430Glu |
M0212144 |
IHOEBPKH_00062 |
71292 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
1290G>A |
Val430Val |
M0212145 |
IHOEBPKH_00062 |
71298 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
1296A>G |
Pro432Pro |
M0212146 |
IHOEBPKH_00062 |
71352 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
1350A>G |
Val450Val |
M0212147 |
IHOEBPKH_00062 |
71388 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
1386C>T |
Val462Val |
M0212148 |
IHOEBPKH_00062 |
71409 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
1407G>A |
Ala469Ala |
M0212149 |
IHOEBPKH_00062 |
71410 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
1408A>T |
Met470Leu |
M0212150 |
IHOEBPKH_00062 |
71419 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
1417G>A |
Glu473Lys |
M0212151 |
IHOEBPKH_00062 |
71442 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
1440G>A |
Leu480Leu |
M0212152 |
IHOEBPKH_00062 |
71505 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
1503A>G |
Gln501Gln |
M0212153 |
IHOEBPKH_00062 |
71583 |
8 |
Gut |
0.11 |
protein_coding |
synonymous_variant |
LOW |
1581C>G |
Ala527Ala |
M0212154 |
IHOEBPKH_00062 |
71589 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
1587G>A |
Ser529Ser |
M0212155 |
IHOEBPKH_00062 |
71625 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
1623T>C |
Ile541Ile |
M0212156 |
IHOEBPKH_00062 |
71691 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
1689A>G |
Ala563Ala |
M0212157 |
IHOEBPKH_00062 |
71716 |
15 |
Gut |
0.20 |
protein_coding |
missense_variant |
MODERATE |
1714T>A |
Cys572Ser |
M0212158 |
IHOEBPKH_00062 |
71718 |
6 |
Gut |
0.08 |
protein_coding |
synonymous_variant |
LOW |
1716C>T |
Cys572Cys |
M0212159 |
IHOEBPKH_00062 |
71721 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
1719C>T |
His573His |
M0212160 |
IHOEBPKH_00062 |
71784 |
9 |
Gut |
0.12 |
protein_coding |
synonymous_variant |
LOW |
1782T>G |
Pro594Pro |
M0212161 |
IHOEBPKH_00062 |
71796 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
1794G>A |
Thr598Thr |
M0212162 |
IHOEBPKH_00062 |
71802 |
13 |
Gut |
0.18 |
protein_coding |
synonymous_variant |
LOW |
1800A>G |
Leu600Leu |
M0212163 |
IHOEBPKH_00062 |
71808 |
8 |
Gut |
0.11 |
protein_coding |
synonymous_variant |
LOW |
1806T>C |
Ile602Ile |
M0212164 |
IHOEBPKH_00062 |
71809 |
13 |
Gut |
0.18 |
protein_coding |
missense_variant |
MODERATE |
1807A>G |
Thr603Ala |
M0212165 |
IHOEBPKH_00062 |
71841 |
6 |
Gut |
0.08 |
protein_coding |
synonymous_variant |
LOW |
1839C>T |
Ile613Ile |
M0212166 |
IHOEBPKH_00062 |
71969 |
10 |
Gut |
0.14 |
protein_coding |
splice_region_variant&stop_retained_variant |
LOW |
1967G>A |
Ter656Ter |
M0212167 |
IHOEBPKH_00064 |
72385 |
7 |
Gut |
0.09 |
protein_coding |
synonymous_variant |
LOW |
45C>T |
Tyr15Tyr |
M0212168 |
IHOEBPKH_00064 |
72448 |
5 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
108T>C |
Ser36Ser |
M0212169 |
IHOEBPKH_00064 |
72526 |
6 |
Gut |
0.08 |
protein_coding |
synonymous_variant |
LOW |
186A>G |
Leu62Leu |
M0212170 |
IHOEBPKH_00064 |
72580 |
5 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
240G>A |
Pro80Pro |
M0212171 |
IHOEBPKH_00064 |
72607 |
5 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
267T>C |
Ile89Ile |
M0212172 |
IHOEBPKH_00064 |
72691 |
10 |
Gut |
0.14 |
protein_coding |
synonymous_variant |
LOW |
351A>T |
Thr117Thr |
M0212173 |
IHOEBPKH_00065 |
72861 |
7 |
Gut |
0.09 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-82C>T |
None |
M0212174 |
IHOEBPKH_00065 |
72864 |
6 |
Gut |
0.08 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-79A>G |
None |
M0212175 |
IHOEBPKH_00065 |
73122 |
18 |
Gut |
0.24 |
protein_coding |
synonymous_variant |
LOW |
180C>T |
Asp60Asp |
M0212176 |
IHOEBPKH_00065 |
73179 |
9 |
Gut |
0.12 |
protein_coding |
synonymous_variant |
LOW |
237A>G |
Gly79Gly |
M0212177 |
IHOEBPKH_00065 |
73191 |
5 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
249A>G |
Ser83Ser |
M0212178 |
IHOEBPKH_00068 |
75094 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
336G>A |
Val112Val |
M0212179 |
IHOEBPKH_00068 |
75115 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
357C>T |
Ser119Ser |
M0212180 |
IHOEBPKH_00068 |
75274 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
516C>A |
Ala172Ala |
M0212181 |
IHOEBPKH_00068 |
75285 |
6 |
Gut |
0.08 |
protein_coding |
missense_variant |
MODERATE |
527A>C |
Glu176Ala |
M0212182 |
IHOEBPKH_00067 |
75314 |
3 |
Gut |
0.04 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-682C>T |
None |
M0212183 |
IHOEBPKH_00070 |
76515 |
6 |
Gut |
0.08 |
protein_coding |
synonymous_variant |
LOW |
18C>G |
Leu6Leu |
M0212184 |
IHOEBPKH_00070 |
76533 |
6 |
Gut |
0.08 |
protein_coding |
synonymous_variant |
LOW |
36T>C |
Ala12Ala |
M0212185 |
IHOEBPKH_00070 |
76575 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
78T>A |
Arg26Arg |
M0212186 |
IHOEBPKH_00070 |
76585 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
88T>C |
Leu30Leu |
M0212187 |
IHOEBPKH_00070 |
76587 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
90A>C |
Leu30Phe |
M0212188 |
IHOEBPKH_00070 |
76602 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
105A>T |
Ile35Ile |
M0212189 |
IHOEBPKH_00070 |
76624 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
127C>T |
Leu43Leu |
M0212190 |
IHOEBPKH_00070 |
76666 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
169C>T |
Leu57Leu |
M0212191 |
IHOEBPKH_00073 |
78214 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
462T>C |
Gly154Gly |
M0212192 |
IHOEBPKH_00073 |
78247 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
429T>C |
Leu143Leu |
M0212193 |
IHOEBPKH_00073 |
78259 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
417A>G |
Val139Val |
M0212194 |
IHOEBPKH_00073 |
78265 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
411A>G |
Ala137Ala |
M0212195 |
IHOEBPKH_00073 |
78292 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
384G>A |
Pro128Pro |
M0212196 |
IHOEBPKH_00073 |
78315 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
361T>C |
Leu121Leu |
M0212197 |
IHOEBPKH_00073 |
78327 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
349G>A |
Val117Ile |
M0212198 |
IHOEBPKH_00073 |
78337 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
339C>A |
Leu113Leu |
M0212199 |
IHOEBPKH_00073 |
78343 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
333A>G |
Gly111Gly |
M0212200 |
IHOEBPKH_00073 |
78355 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
321T>C |
Gly107Gly |
M0212201 |
IHOEBPKH_00073 |
78363 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
313G>C |
Val105Leu |
M0212202 |
IHOEBPKH_00073 |
78375 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
301T>C |
Leu101Leu |
M0212203 |
IHOEBPKH_00073 |
78399 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
277G>A |
Val93Ile |
M0212204 |
IHOEBPKH_00073 |
78403 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
273A>G |
Ala91Ala |
M0212205 |
IHOEBPKH_00073 |
78460 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
216T>C |
Thr72Thr |
M0212206 |
IHOEBPKH_00073 |
78488 |
4 |
Gut |
0.05 |
protein_coding |
missense_variant |
MODERATE |
188T>C |
Ile63Thr |
M0212207 |
IHOEBPKH_00073 |
78514 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
162T>C |
Ser54Ser |
M0212208 |
IHOEBPKH_00073 |
78562 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
114C>A |
Ser38Ser |
M0212209 |
IHOEBPKH_00073 |
78571 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
105C>T |
Tyr35Tyr |
M0212210 |
IHOEBPKH_00073 |
78604 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
72C>T |
Val24Val |
M0212211 |
IHOEBPKH_00073 |
78628 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
48G>A |
Ala16Ala |
M0212212 |
IHOEBPKH_00073 |
78648 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
28A>G |
Thr10Ala |
M0212213 |
IHOEBPKH_00073 |
78654 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
22G>A |
Val8Ile |
M0212214 |
IHOEBPKH_00073 |
78669 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
7A>T |
Ser3Cys |
M0212215 |
IHOEBPKH_00067 |
78693 |
3 |
Gut |
0.04 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4061C>T |
None |
M0212216 |
IHOEBPKH_00067 |
78727 |
3 |
Gut |
0.04 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4095C>T |
None |
M0212217 |
IHOEBPKH_00067 |
78770 |
3 |
Gut |
0.04 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4138G>A |
None |
M0212218 |
IHOEBPKH_00067 |
78970 |
3 |
Gut |
0.04 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4338A>T |
None |
M0212219 |
IHOEBPKH_00067 |
78981 |
3 |
Gut |
0.04 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4349A>G |
None |
M0212220 |
IHOEBPKH_00067 |
78995 |
3 |
Gut |
0.04 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4363T>A |
None |
M0212221 |
IHOEBPKH_00067 |
79005 |
3 |
Gut |
0.04 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4373C>T |
None |
M0212222 |
IHOEBPKH_00074 |
79034 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
492T>G |
Thr164Thr |
M0212223 |
IHOEBPKH_00074 |
79051 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
475A>C |
Met159Leu |
M0212224 |
IHOEBPKH_00074 |
79052 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
474C>T |
His158His |
M0212225 |
IHOEBPKH_00074 |
79076 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
450A>T |
Pro150Pro |
M0212226 |
IHOEBPKH_00074 |
79077 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
449C>T |
Pro150Leu |
M0212227 |
IHOEBPKH_00074 |
79078 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
448C>G |
Pro150Ala |
M0212228 |
IHOEBPKH_00074 |
79079 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
447G>A |
Ala149Ala |
M0212229 |
IHOEBPKH_00074 |
79080 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
446C>A |
Ala149Glu |
M0212230 |
IHOEBPKH_00074 |
79103 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
423G>A |
Leu141Leu |
M0212231 |
IHOEBPKH_00074 |
79133 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
393A>G |
Leu131Leu |
M0212232 |
IHOEBPKH_00074 |
79163 |
5 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
363A>G |
Gln121Gln |
M0212233 |
IHOEBPKH_00074 |
79172 |
5 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
354C>T |
Cys118Cys |
M0212234 |
IHOEBPKH_00074 |
79187 |
5 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
339C>T |
Gly113Gly |
M0212235 |
IHOEBPKH_00074 |
79190 |
5 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
336G>A |
Leu112Leu |
M0212236 |
IHOEBPKH_00074 |
79211 |
5 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
315A>G |
Leu105Leu |
M0212237 |
IHOEBPKH_00074 |
79253 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
273T>C |
Thr91Thr |
M0212238 |
IHOEBPKH_00074 |
79259 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
267A>G |
Lys89Lys |
M0212239 |
IHOEBPKH_00074 |
79271 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
255C>A |
Pro85Pro |
M0212240 |
IHOEBPKH_00074 |
79286 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
240G>A |
Lys80Lys |
M0212241 |
IHOEBPKH_00074 |
79310 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
216C>T |
Ile72Ile |
M0212242 |
IHOEBPKH_00074 |
79361 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
165G>A |
Gly55Gly |
M0212243 |
IHOEBPKH_00074 |
79364 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
162A>G |
Glu54Glu |
M0212244 |
IHOEBPKH_00074 |
79388 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
138T>C |
His46His |
M0212245 |
IHOEBPKH_00074 |
79402 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
124C>T |
Leu42Leu |
M0212246 |
IHOEBPKH_00074 |
79415 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
111T>A |
Pro37Pro |
M0212247 |
IHOEBPKH_00074 |
79438 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
88T>C |
Leu30Leu |
M0212248 |
IHOEBPKH_00074 |
79460 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
66G>A |
Glu22Glu |
M0212249 |
IHOEBPKH_00074 |
79463 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
63G>A |
Val21Val |
M0212250 |
IHOEBPKH_00074 |
79466 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
60A>G |
Lys20Lys |
M0212251 |
IHOEBPKH_00074 |
79474 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
52G>A |
Gly18Ser |
M0212252 |
IHOEBPKH_00074 |
79475 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
51T>C |
Ser17Ser |
M0212253 |
IHOEBPKH_00071 |
79668 |
3 |
Gut |
0.04 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2509C>T |
None |
M0212254 |
IHOEBPKH_00071 |
79695 |
3 |
Gut |
0.04 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2536T>A |
None |
M0212255 |
IHOEBPKH_00071 |
79857 |
3 |
Gut |
0.04 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2698C>T |
None |
M0212256 |
IHOEBPKH_00071 |
79866 |
4 |
Gut |
0.05 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2707G>A |
None |
M0212257 |
IHOEBPKH_00071 |
79878 |
4 |
Gut |
0.05 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2719A>G |
None |
M0212258 |
IHOEBPKH_00071 |
79911 |
4 |
Gut |
0.05 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2752A>G |
None |
M0212259 |
IHOEBPKH_00071 |
79920 |
4 |
Gut |
0.05 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2761A>T |
None |
M0212260 |
IHOEBPKH_00071 |
79926 |
4 |
Gut |
0.05 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2767A>G |
None |
M0212261 |
IHOEBPKH_00071 |
79929 |
4 |
Gut |
0.05 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2770C>G |
None |
M0212262 |
IHOEBPKH_00071 |
79995 |
4 |
Gut |
0.05 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2836G>T |
None |
M0212263 |
IHOEBPKH_00062 |
71499 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
1497C>A |
Ser499Ser |
M0212264 |
IHOEBPKH_00062 |
71543 |
5 |
Gut |
0.07 |
protein_coding |
missense_variant |
MODERATE |
1541A>G |
Lys514Arg |
M0212265 |
IHOEBPKH_00062 |
71658 |
6 |
Gut |
0.08 |
protein_coding |
synonymous_variant |
LOW |
1656T>G |
Leu552Leu |
M0212266 |
IHOEBPKH_00062 |
71702 |
7 |
Gut |
0.09 |
protein_coding |
missense_variant |
MODERATE |
1700G>T |
Arg567Leu |
M0212267 |
IHOEBPKH_00062 |
71720 |
7 |
Gut |
0.09 |
protein_coding |
missense_variant |
MODERATE |
1718A>G |
His573Arg |
M0212268 |
IHOEBPKH_00062 |
71800 |
7 |
Gut |
0.09 |
protein_coding |
synonymous_variant |
LOW |
1798T>C |
Leu600Leu |
M0212269 |
IHOEBPKH_00062 |
71883 |
10 |
Gut |
0.14 |
protein_coding |
synonymous_variant |
LOW |
1881C>T |
Ile627Ile |
M0212270 |
IHOEBPKH_00064 |
72298 |
10 |
Gut |
0.14 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-43C>T |
None |
M0212271 |
IHOEBPKH_00064 |
72323 |
7 |
Gut |
0.09 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-18T>C |
None |
M0212272 |
IHOEBPKH_00064 |
72451 |
19 |
Gut |
0.26 |
protein_coding |
synonymous_variant |
LOW |
111T>C |
His37His |
M0212273 |
IHOEBPKH_00064 |
72598 |
8 |
Gut |
0.11 |
protein_coding |
synonymous_variant |
LOW |
258C>T |
Ala86Ala |
M0212274 |
IHOEBPKH_00065 |
73215 |
14 |
Gut |
0.19 |
protein_coding |
synonymous_variant |
LOW |
273A>G |
Ala91Ala |
M0212275 |
IHOEBPKH_00065 |
73347 |
6 |
Gut |
0.08 |
protein_coding |
synonymous_variant |
LOW |
405T>C |
Phe135Phe |
M0212276 |
IHOEBPKH_00065 |
73356 |
10 |
Gut |
0.14 |
protein_coding |
synonymous_variant |
LOW |
414A>T |
Ala138Ala |
M0212277 |
IHOEBPKH_00065 |
73401 |
10 |
Gut |
0.14 |
protein_coding |
synonymous_variant |
LOW |
459A>C |
Pro153Pro |
M0212278 |
IHOEBPKH_00065 |
73593 |
9 |
Gut |
0.12 |
protein_coding |
synonymous_variant |
LOW |
651A>G |
Gly217Gly |
M0212279 |
IHOEBPKH_00065 |
73602 |
9 |
Gut |
0.12 |
protein_coding |
synonymous_variant |
LOW |
660T>G |
Thr220Thr |
M0212280 |
IHOEBPKH_00065 |
73624 |
7 |
Gut |
0.09 |
protein_coding |
missense_variant |
MODERATE |
682C>T |
Arg228Trp |
M0212281 |
IHOEBPKH_00066 |
73861 |
8 |
Gut |
0.11 |
protein_coding |
synonymous_variant |
LOW |
42T>C |
Gly14Gly |
M0212282 |
IHOEBPKH_00068 |
74297 |
5 |
Gut |
0.07 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-462A>G |
None |
M0212283 |
IHOEBPKH_00067 |
74375 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
258A>G |
Leu86Leu |
M0212284 |
IHOEBPKH_00067 |
74465 |
5 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
168T>C |
Cys56Cys |
M0212285 |
IHOEBPKH_00065 |
73050 |
6 |
Gut |
0.08 |
protein_coding |
synonymous_variant |
LOW |
108G>A |
Val36Val |
M0212286 |
IHOEBPKH_00065 |
73153 |
7 |
Gut |
0.09 |
protein_coding |
synonymous_variant |
LOW |
211C>T |
Leu71Leu |
M0212287 |
IHOEBPKH_00065 |
73197 |
7 |
Gut |
0.09 |
protein_coding |
synonymous_variant |
LOW |
255T>G |
Val85Val |
M0212288 |
IHOEBPKH_00065 |
73350 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
408A>C |
Pro136Pro |
M0212289 |
IHOEBPKH_00065 |
73359 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
417T>C |
Tyr139Tyr |
M0212290 |
IHOEBPKH_00065 |
73365 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
423G>A |
Ala141Ala |
M0212291 |
IHOEBPKH_00065 |
73392 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
450T>G |
Val150Val |
M0212292 |
IHOEBPKH_00065 |
73404 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
462G>A |
Lys154Lys |
M0212293 |
IHOEBPKH_00065 |
73413 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
471T>C |
Ile157Ile |
M0212294 |
IHOEBPKH_00065 |
73425 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
483T>C |
Gly161Gly |
M0212295 |
IHOEBPKH_00065 |
73437 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
495T>C |
Ala165Ala |
M0212296 |
IHOEBPKH_00065 |
73482 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
540T>C |
Cys180Cys |
M0212297 |
IHOEBPKH_00065 |
73530 |
8 |
Gut |
0.11 |
protein_coding |
synonymous_variant |
LOW |
588A>C |
Ser196Ser |
M0212298 |
IHOEBPKH_00065 |
73749 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
807G>A |
Arg269Arg |
M0212299 |
IHOEBPKH_00066 |
73885 |
10 |
Gut |
0.14 |
protein_coding |
synonymous_variant |
LOW |
66A>G |
Gly22Gly |
M0212300 |
IHOEBPKH_00066 |
73900 |
6 |
Gut |
0.08 |
protein_coding |
synonymous_variant |
LOW |
81C>A |
Arg27Arg |
M0212301 |
IHOEBPKH_00066 |
73903 |
6 |
Gut |
0.08 |
protein_coding |
synonymous_variant |
LOW |
84T>C |
Phe28Phe |
M0212302 |
IHOEBPKH_00066 |
73912 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
93C>A |
Gly31Gly |
M0212303 |
IHOEBPKH_00066 |
73949 |
10 |
Gut |
0.14 |
protein_coding |
synonymous_variant |
LOW |
130T>C |
Leu44Leu |
M0212304 |
IHOEBPKH_00066 |
73960 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
141C>A |
Pro47Pro |
M0212305 |
IHOEBPKH_00066 |
73963 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
144C>T |
Arg48Arg |
M0212306 |
IHOEBPKH_00066 |
73972 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
153G>A |
Ala51Ala |
M0212307 |
IHOEBPKH_00066 |
73975 |
6 |
Gut |
0.08 |
protein_coding |
synonymous_variant |
LOW |
156A>G |
Gln52Gln |
M0212308 |
IHOEBPKH_00066 |
74120 |
4 |
Gut |
0.05 |
protein_coding |
missense_variant |
MODERATE |
301A>G |
Lys101Glu |
M0212309 |
IHOEBPKH_00067 |
74455 |
4 |
Gut |
0.05 |
protein_coding |
missense_variant |
MODERATE |
178C>A |
His60Asn |
M0212310 |
IHOEBPKH_00067 |
74456 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
177T>C |
Leu59Leu |
M0212311 |
IHOEBPKH_00067 |
74474 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
159C>T |
Leu53Leu |
M0212312 |
IHOEBPKH_00067 |
74483 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
150G>A |
Glu50Glu |
M0212313 |
IHOEBPKH_00067 |
74489 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
144G>A |
Arg48Arg |
M0212314 |
IHOEBPKH_00067 |
74491 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
142C>A |
Arg48Arg |
M0212315 |
IHOEBPKH_00067 |
74548 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
85C>T |
Leu29Leu |
M0212316 |
IHOEBPKH_00067 |
74564 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
69A>G |
Gln23Gln |
M0212317 |
IHOEBPKH_00067 |
74606 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
27T>C |
Gly9Gly |
M0212318 |
IHOEBPKH_00066 |
73927 |
8 |
Gut |
0.11 |
protein_coding |
synonymous_variant |
LOW |
108G>A |
Glu36Glu |
M0212319 |
IHOEBPKH_00066 |
73928 |
8 |
Gut |
0.11 |
protein_coding |
missense_variant |
MODERATE |
109A>G |
Thr37Ala |
M0212320 |
IHOEBPKH_00070 |
76555 |
5 |
Gut |
0.07 |
protein_coding |
missense_variant |
MODERATE |
58G>A |
Ala20Thr |
M0212321 |
IHOEBPKH_00070 |
76665 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
168A>G |
Lys56Lys |
M0212322 |
IHOEBPKH_00071 |
76896 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
264G>A |
Gln88Gln |
M0212323 |
IHOEBPKH_00071 |
76899 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
261A>C |
Arg87Ser |
M0212324 |
IHOEBPKH_00095 |
96742 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
166T>C |
Leu56Leu |
M0212325 |
IHOEBPKH_00095 |
96749 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
159A>G |
Val53Val |
M0212326 |
IHOEBPKH_00087 |
96931 |
3 |
Gut |
0.04 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4827A>C |
None |
M0212327 |
IHOEBPKH_00087 |
96934 |
3 |
Gut |
0.04 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4830G>A |
None |
M0212328 |
IHOEBPKH_00087 |
96943 |
3 |
Gut |
0.04 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4839C>T |
None |
M0212329 |
IHOEBPKH_00096 |
96989 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
780A>T |
Ala260Ala |
M0212330 |
IHOEBPKH_00096 |
97013 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
756A>T |
Val252Val |
M0212331 |
IHOEBPKH_00096 |
97154 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
615T>C |
Ser205Ser |
M0212332 |
IHOEBPKH_00096 |
97165 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
604A>G |
Thr202Ala |
M0212333 |
IHOEBPKH_00096 |
97214 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
555C>T |
Pro185Pro |
M0212334 |
IHOEBPKH_00096 |
97247 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
522T>C |
Gly174Gly |
M0212335 |
IHOEBPKH_00096 |
97249 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
520G>A |
Gly174Ser |
M0212336 |
IHOEBPKH_00096 |
97250 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
519C>A |
Thr173Thr |
M0212337 |
IHOEBPKH_00086 |
91188 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
381T>G |
Ser127Ser |
M0212338 |
IHOEBPKH_00086 |
91308 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
261G>A |
Gln87Gln |
M0212339 |
IHOEBPKH_00086 |
91404 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
165C>T |
Ala55Ala |
M0212340 |
IHOEBPKH_00086 |
91407 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
162G>A |
Ala54Ala |
M0212341 |
IHOEBPKH_00086 |
91554 |
5 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
15T>C |
Ser5Ser |
M0212342 |
IHOEBPKH_00087 |
91618 |
4 |
Gut |
0.05 |
protein_coding |
missense_variant |
MODERATE |
487G>A |
Glu163Lys |
M0212343 |
IHOEBPKH_00087 |
91646 |
5 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
459C>T |
Gly153Gly |
M0212344 |
IHOEBPKH_00087 |
91694 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
411G>A |
Lys137Lys |
M0212345 |
IHOEBPKH_00087 |
91829 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
276C>T |
Phe92Phe |
M0212346 |
IHOEBPKH_00087 |
91931 |
5 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
174T>C |
Asp58Asp |
M0212347 |
IHOEBPKH_00087 |
92009 |
5 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
96A>G |
Lys32Lys |
M0212348 |
IHOEBPKH_00087 |
92045 |
5 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
60C>T |
Asn20Asn |
M0212349 |
IHOEBPKH_00088 |
92266 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
52C>T |
Pro18Ser |
M0212350 |
IHOEBPKH_00089 |
92373 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
393A>G |
Leu131Leu |
M0212351 |
IHOEBPKH_00089 |
92418 |
5 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
348C>A |
Arg116Arg |
M0212352 |
IHOEBPKH_00089 |
92434 |
5 |
Gut |
0.07 |
protein_coding |
missense_variant |
MODERATE |
332A>G |
Lys111Arg |
M0212353 |
IHOEBPKH_00089 |
92442 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
324T>C |
Ala108Ala |
M0212354 |
IHOEBPKH_00089 |
92457 |
5 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
309T>C |
Tyr103Tyr |
M0212355 |
IHOEBPKH_00089 |
92641 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
125C>T |
Ala42Val |
M0212356 |
IHOEBPKH_00089 |
92668 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
98C>T |
Thr33Ile |
M0212357 |
IHOEBPKH_00089 |
92709 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
57G>A |
Ala19Ala |
M0212358 |
IHOEBPKH_00091 |
93696 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
210A>G |
Pro70Pro |
M0212359 |
IHOEBPKH_00091 |
93699 |
6 |
Gut |
0.08 |
protein_coding |
missense_variant |
MODERATE |
207G>T |
Glu69Asp |
M0212360 |
IHOEBPKH_00091 |
93752 |
5 |
Gut |
0.07 |
protein_coding |
missense_variant |
MODERATE |
154G>A |
Ala52Thr |
M0212361 |
IHOEBPKH_00091 |
93753 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
153G>A |
Arg51Arg |
M0212362 |
IHOEBPKH_00091 |
93759 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
147C>T |
Tyr49Tyr |
M0212363 |
IHOEBPKH_00091 |
93765 |
5 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
141C>T |
Ala47Ala |
M0212364 |
IHOEBPKH_00091 |
93773 |
6 |
Gut |
0.08 |
protein_coding |
missense_variant |
MODERATE |
133T>C |
Cys45Arg |
M0212365 |
IHOEBPKH_00091 |
93789 |
6 |
Gut |
0.08 |
protein_coding |
synonymous_variant |
LOW |
117G>A |
Glu39Glu |
M0212366 |
IHOEBPKH_00091 |
93798 |
5 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
108C>A |
Val36Val |
M0212367 |
IHOEBPKH_00091 |
93852 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
54T>C |
Phe18Phe |
M0212368 |
IHOEBPKH_00091 |
93875 |
4 |
Gut |
0.05 |
protein_coding |
missense_variant |
MODERATE |
31C>T |
Pro11Ser |
M0212369 |
IHOEBPKH_00091 |
93882 |
4 |
Gut |
0.05 |
protein_coding |
missense_variant |
MODERATE |
24G>T |
Glu8Asp |
M0212370 |
IHOEBPKH_00083 |
93977 |
6 |
Gut |
0.08 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4998A>C |
None |
M0212371 |
IHOEBPKH_00084 |
94005 |
5 |
Gut |
0.07 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4378G>A |
None |
M0212372 |
IHOEBPKH_00092 |
94183 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
73A>C |
Ile25Leu |
M0212373 |
IHOEBPKH_00092 |
94193 |
5 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
63A>G |
Gly21Gly |
M0212374 |
IHOEBPKH_00093 |
94442 |
6 |
Gut |
0.08 |
protein_coding |
synonymous_variant |
LOW |
417A>G |
Val139Val |
M0212375 |
IHOEBPKH_00093 |
94553 |
5 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
306C>G |
Ala102Ala |
M0212376 |
IHOEBPKH_00068 |
75160 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
402G>A |
Gly134Gly |
M0212377 |
IHOEBPKH_00068 |
75161 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
403C>T |
His135Tyr |
M0212378 |
IHOEBPKH_00169 |
168488 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
360T>C |
Phe120Phe |
M0212379 |
IHOEBPKH_00169 |
168491 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
363G>A |
Gln121Gln |
M0212380 |
IHOEBPKH_00169 |
168494 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
366C>G |
Val122Val |
M0212381 |
IHOEBPKH_00169 |
168500 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
372C>T |
Ile124Ile |
M0212382 |
IHOEBPKH_00169 |
168661 |
5 |
Gut |
0.07 |
protein_coding |
missense_variant |
MODERATE |
533G>A |
Cys178Tyr |
M0212383 |
IHOEBPKH_00169 |
168669 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
541G>A |
Asp181Asn |
M0212384 |
IHOEBPKH_00169 |
168678 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
550G>A |
Ala184Thr |
M0212385 |
IHOEBPKH_00169 |
168698 |
7 |
Gut |
0.09 |
protein_coding |
synonymous_variant |
LOW |
570T>G |
Leu190Leu |
M0212386 |
IHOEBPKH_00169 |
168704 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
576G>A |
Glu192Glu |
M0212387 |
IHOEBPKH_00169 |
168719 |
7 |
Gut |
0.09 |
protein_coding |
synonymous_variant |
LOW |
591A>G |
Pro197Pro |
M0212388 |
IHOEBPKH_00169 |
168730 |
4 |
Gut |
0.05 |
protein_coding |
missense_variant |
MODERATE |
602A>G |
Asn201Ser |
M0212389 |
IHOEBPKH_00169 |
168770 |
5 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
642A>G |
Ser214Ser |
M0212390 |
IHOEBPKH_00169 |
168869 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
741A>G |
Arg247Arg |
M0212391 |
IHOEBPKH_00169 |
169197 |
4 |
Gut |
0.05 |
protein_coding |
missense_variant |
MODERATE |
1069C>A |
Leu357Ile |
M0212392 |
IHOEBPKH_00067 |
74742 |
3 |
Gut |
0.04 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-110G>A |
None |
M0212393 |
IHOEBPKH_00068 |
74910 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
152T>C |
Val51Ala |
M0212394 |
IHOEBPKH_00068 |
74917 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
159A>G |
Gly53Gly |
M0212395 |
IHOEBPKH_00068 |
74928 |
6 |
Gut |
0.08 |
protein_coding |
missense_variant |
MODERATE |
170T>C |
Val57Ala |
M0212396 |
IHOEBPKH_00068 |
74948 |
9 |
Gut |
0.12 |
protein_coding |
missense_variant |
MODERATE |
190C>A |
Leu64Ile |
M0212397 |
IHOEBPKH_00068 |
74959 |
9 |
Gut |
0.12 |
protein_coding |
synonymous_variant |
LOW |
201T>C |
Arg67Arg |
M0212398 |
IHOEBPKH_00068 |
74968 |
9 |
Gut |
0.12 |
protein_coding |
synonymous_variant |
LOW |
210G>A |
Glu70Glu |
M0212399 |
IHOEBPKH_00068 |
74998 |
8 |
Gut |
0.11 |
protein_coding |
synonymous_variant |
LOW |
240T>C |
Cys80Cys |
M0212400 |
IHOEBPKH_00068 |
75023 |
7 |
Gut |
0.09 |
protein_coding |
missense_variant |
MODERATE |
265A>G |
Asn89Asp |
M0212401 |
IHOEBPKH_00065 |
73458 |
9 |
Gut |
0.12 |
protein_coding |
synonymous_variant |
LOW |
516C>T |
Asn172Asn |
M0212402 |
IHOEBPKH_00065 |
73642 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
700G>A |
Ala234Thr |
M0212403 |
IHOEBPKH_00065 |
73698 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
756G>A |
Leu252Leu |
M0212404 |
IHOEBPKH_00065 |
73701 |
5 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
759A>G |
Gln253Gln |
M0212405 |
IHOEBPKH_00065 |
73746 |
5 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
804G>A |
Lys268Lys |
M0212406 |
IHOEBPKH_00066 |
73886 |
6 |
Gut |
0.08 |
protein_coding |
synonymous_variant |
LOW |
67C>A |
Arg23Arg |
M0212407 |
IHOEBPKH_00066 |
73924 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
105C>T |
His35His |
M0212408 |
IHOEBPKH_00066 |
73936 |
5 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
117T>A |
Ile39Ile |
M0212409 |
IHOEBPKH_00066 |
73942 |
6 |
Gut |
0.08 |
protein_coding |
synonymous_variant |
LOW |
123A>G |
Leu41Leu |
M0212410 |
IHOEBPKH_00066 |
73966 |
6 |
Gut |
0.08 |
protein_coding |
synonymous_variant |
LOW |
147A>G |
Thr49Thr |
M0212411 |
IHOEBPKH_00068 |
74296 |
3 |
Gut |
0.04 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-463G>A |
None |
M0212412 |
IHOEBPKH_00067 |
74377 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
256C>T |
Leu86Leu |
M0212413 |
IHOEBPKH_00067 |
74567 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
66C>T |
Thr22Thr |
M0212414 |
IHOEBPKH_00067 |
75414 |
3 |
Gut |
0.04 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-782G>T |
None |
M0212415 |
IHOEBPKH_00067 |
75426 |
3 |
Gut |
0.04 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-794A>T |
None |
M0212416 |
IHOEBPKH_00070 |
76512 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
15T>C |
Cys5Cys |
M0212417 |
IHOEBPKH_00070 |
76543 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
46G>A |
Asp16Asn |
M0212418 |
IHOEBPKH_00062 |
71385 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
1383A>C |
Leu461Phe |
M0212419 |
IHOEBPKH_00062 |
71571 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
1569T>G |
Thr523Thr |
M0212420 |
IHOEBPKH_00062 |
71619 |
5 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
1617T>C |
Phe539Phe |
M0212421 |
IHOEBPKH_00064 |
72424 |
5 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
84A>G |
Pro28Pro |
M0212422 |
IHOEBPKH_00064 |
72505 |
5 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
165G>T |
Thr55Thr |
M0212423 |
IHOEBPKH_00067 |
75559 |
4 |
Gut |
0.05 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-927A>G |
None |
M0212424 |
IHOEBPKH_00067 |
75585 |
4 |
Gut |
0.05 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-953T>C |
None |
M0212425 |
IHOEBPKH_00067 |
75616 |
4 |
Gut |
0.05 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-984G>T |
None |
M0212426 |
IHOEBPKH_00067 |
75626 |
4 |
Gut |
0.05 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-994A>G |
None |
M0212427 |
IHOEBPKH_00067 |
75780 |
4 |
Gut |
0.05 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-1148T>C |
None |
M0212428 |
IHOEBPKH_00067 |
75882 |
3 |
Gut |
0.04 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-1250C>T |
None |
M0212429 |
IHOEBPKH_00067 |
75926 |
3 |
Gut |
0.04 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-1294A>G |
None |
M0212430 |
IHOEBPKH_00067 |
75929 |
3 |
Gut |
0.04 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-1297A>G |
None |
M0212431 |
IHOEBPKH_00067 |
75960 |
3 |
Gut |
0.04 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-1328C>T |
None |
M0212432 |
IHOEBPKH_00067 |
76004 |
3 |
Gut |
0.04 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-1372C>G |
None |
M0212433 |
IHOEBPKH_00067 |
76006 |
3 |
Gut |
0.04 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-1374A>G |
None |
M0212434 |
IHOEBPKH_00067 |
76059 |
3 |
Gut |
0.04 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-1427A>G |
None |
M0212435 |
IHOEBPKH_00067 |
76065 |
3 |
Gut |
0.04 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-1433T>C |
None |
M0212436 |
IHOEBPKH_00069 |
76114 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
21A>G |
Gly7Gly |
M0212437 |
IHOEBPKH_00080 |
86198 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
505T>C |
Leu169Leu |
M0212438 |
IHOEBPKH_00081 |
86731 |
4 |
Gut |
0.05 |
protein_coding |
stop_gained |
HIGH |
706G>T |
Glu236* |
M0212439 |
IHOEBPKH_00081 |
86855 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
582C>T |
Gly194Gly |
M0212440 |
IHOEBPKH_00081 |
87074 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
363G>A |
Glu121Glu |
M0212441 |
IHOEBPKH_00076 |
87520 |
4 |
Gut |
0.05 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4245G>T |
None |
M0212442 |
IHOEBPKH_00083 |
87932 |
4 |
Gut |
0.05 |
protein_coding |
missense_variant |
MODERATE |
1048A>G |
Arg350Gly |
M0212443 |
IHOEBPKH_00083 |
88038 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
942A>C |
Ile314Ile |
M0212444 |
IHOEBPKH_00083 |
88047 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
933T>C |
Thr311Thr |
M0212445 |
IHOEBPKH_00083 |
88091 |
4 |
Gut |
0.05 |
protein_coding |
missense_variant |
MODERATE |
889A>G |
Asn297Asp |
M0212446 |
IHOEBPKH_00083 |
88428 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
552T>C |
Gly184Gly |
M0212447 |
IHOEBPKH_00087 |
91598 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
507T>C |
Val169Val |
M0212448 |
IHOEBPKH_00087 |
91634 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
471T>C |
Leu157Leu |
M0212449 |
IHOEBPKH_00087 |
91637 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
468G>A |
Gln156Gln |
M0212450 |
IHOEBPKH_00087 |
91661 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
444T>C |
Cys148Cys |
M0212451 |
IHOEBPKH_00087 |
91706 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
399C>T |
Asp133Asp |
M0212452 |
IHOEBPKH_00089 |
92682 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
84A>G |
Leu28Leu |
M0212453 |
IHOEBPKH_00089 |
92757 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
9A>G |
Glu3Glu |
M0212454 |
IHOEBPKH_00090 |
92800 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
387G>A |
Pro129Pro |
M0212455 |
IHOEBPKH_00090 |
92833 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
354T>C |
Thr118Thr |
M0212456 |
IHOEBPKH_00090 |
92894 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
293A>C |
Asp98Ala |
M0212457 |
IHOEBPKH_00090 |
92923 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
264A>G |
Glu88Glu |
M0212458 |
IHOEBPKH_00090 |
92985 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
202T>G |
Ser68Ala |
M0212459 |
IHOEBPKH_00090 |
93109 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
78C>T |
Asp26Asp |
M0212460 |
IHOEBPKH_00090 |
93132 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
55A>G |
Thr19Ala |
M0212461 |
IHOEBPKH_00090 |
93133 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
54C>T |
Pro18Pro |
M0212462 |
IHOEBPKH_00090 |
93166 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
21G>A |
Ala7Ala |
M0212463 |
IHOEBPKH_00091 |
93369 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
537T>A |
Ile179Ile |
M0212464 |
IHOEBPKH_00091 |
93405 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
501A>G |
Glu167Glu |
M0212465 |
IHOEBPKH_00091 |
93415 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
491A>G |
Gln164Arg |
M0212466 |
IHOEBPKH_00091 |
93441 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
465A>G |
Lys155Lys |
M0212467 |
IHOEBPKH_00091 |
93583 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
323A>G |
His108Arg |
M0212468 |
IHOEBPKH_00091 |
93646 |
4 |
Gut |
0.05 |
protein_coding |
missense_variant |
MODERATE |
260T>C |
Val87Ala |
M0212469 |
IHOEBPKH_00091 |
93684 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
222C>T |
Thr74Thr |
M0212470 |
IHOEBPKH_00092 |
94154 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
102T>C |
His34His |
M0212471 |
IHOEBPKH_00093 |
94334 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
525C>T |
Asp175Asp |
M0212472 |
IHOEBPKH_00094 |
95013 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
783C>T |
Gly261Gly |
M0212473 |
IHOEBPKH_00094 |
95022 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
774C>G |
Pro258Pro |
M0212474 |
IHOEBPKH_00094 |
95052 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
744G>A |
Val248Val |
M0212475 |
IHOEBPKH_00094 |
95091 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
705A>G |
Glu235Glu |
M0212476 |
IHOEBPKH_00094 |
95094 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
702T>C |
Ala234Ala |
M0212477 |
IHOEBPKH_00094 |
95100 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
696A>G |
Gln232Gln |
M0212478 |
IHOEBPKH_00094 |
95103 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
693A>G |
Gln231Gln |
M0212479 |
IHOEBPKH_00094 |
95121 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
675A>G |
Gln225Gln |
M0212480 |
IHOEBPKH_00094 |
95133 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
663C>T |
Ser221Ser |
M0212481 |
IHOEBPKH_00094 |
95136 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
660T>C |
Asn220Asn |
M0212482 |
IHOEBPKH_00094 |
95148 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
648A>G |
Arg216Arg |
M0212483 |
IHOEBPKH_00094 |
95175 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
621T>C |
Phe207Phe |
M0212484 |
IHOEBPKH_00094 |
95232 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
564A>T |
Arg188Arg |
M0212485 |
IHOEBPKH_00094 |
95241 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
555C>T |
Gly185Gly |
M0212486 |
IHOEBPKH_00094 |
95256 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
540C>T |
Ser180Ser |
M0212487 |
IHOEBPKH_00094 |
95259 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
537T>C |
Gly179Gly |
M0212488 |
IHOEBPKH_00094 |
95265 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
531A>T |
Thr177Thr |
M0212489 |
IHOEBPKH_00094 |
95286 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
510T>C |
Phe170Phe |
M0212490 |
IHOEBPKH_00094 |
95289 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
507T>C |
Ala169Ala |
M0212491 |
IHOEBPKH_00094 |
95328 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
468C>T |
Pro156Pro |
M0212492 |
IHOEBPKH_00094 |
95358 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
438A>G |
Glu146Glu |
M0212493 |
IHOEBPKH_00094 |
95583 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
213T>C |
Gly71Gly |
M0212494 |
IHOEBPKH_00094 |
95640 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
156G>A |
Gln52Gln |
M0212495 |
IHOEBPKH_00094 |
95679 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
117C>T |
Ser39Ser |
M0212496 |
IHOEBPKH_00085 |
95815 |
3 |
Gut |
0.04 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4857A>G |
None |
M0212497 |
IHOEBPKH_00095 |
95987 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
921G>A |
Lys307Lys |
M0212498 |
IHOEBPKH_00095 |
95998 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
910C>A |
Leu304Ile |
M0212499 |
IHOEBPKH_00095 |
96254 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
654A>G |
Arg218Arg |
M0212500 |
IHOEBPKH_00095 |
96293 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
615T>C |
Val205Val |
M0212501 |
IHOEBPKH_00164 |
165267 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
621T>C |
Ser207Ser |
M0212502 |
IHOEBPKH_00164 |
165295 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
649T>C |
Cys217Arg |
M0212503 |
IHOEBPKH_00164 |
165297 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
651T>C |
Cys217Cys |
M0212504 |
IHOEBPKH_00164 |
165309 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
663C>T |
Ser221Ser |
M0212505 |
IHOEBPKH_00164 |
165315 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
669T>C |
Thr223Thr |
M0212506 |
IHOEBPKH_00164 |
165327 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
681G>A |
Leu227Leu |
M0212507 |
IHOEBPKH_00164 |
165345 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
699C>T |
Thr233Thr |
M0212508 |
IHOEBPKH_00164 |
165348 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
702G>A |
Lys234Lys |
M0212509 |
IHOEBPKH_00164 |
165355 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
709G>A |
Asp237Asn |
M0212510 |
IHOEBPKH_00165 |
166301 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
714T>C |
His238His |
M0212511 |
IHOEBPKH_00166 |
166737 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
414G>A |
Val138Val |
M0212512 |
IHOEBPKH_00166 |
166740 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
417C>T |
Phe139Phe |
M0212513 |
IHOEBPKH_00166 |
166743 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
420A>C |
Pro140Pro |
M0212514 |
IHOEBPKH_00166 |
166812 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
489A>G |
Gly163Gly |
M0212515 |
IHOEBPKH_00166 |
166950 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
627C>T |
Asp209Asp |
M0212516 |
IHOEBPKH_00169 |
168790 |
5 |
Gut |
0.07 |
protein_coding |
missense_variant |
MODERATE |
662T>A |
Leu221Gln |
M0212517 |
IHOEBPKH_00169 |
168794 |
5 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
666C>T |
Arg222Arg |
M0212518 |
IHOEBPKH_00170 |
169806 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
318T>C |
Arg106Arg |
M0212519 |
IHOEBPKH_00170 |
169836 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
348C>T |
Ile116Ile |
M0212520 |
IHOEBPKH_00170 |
169899 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
411A>C |
Ala137Ala |
M0212521 |
IHOEBPKH_00170 |
170201 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
713G>C |
Ser238Thr |
M0212522 |
IHOEBPKH_00170 |
170208 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
720T>C |
Asp240Asp |
M0212523 |
IHOEBPKH_00170 |
170251 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
763G>A |
Glu255Lys |
M0212524 |
IHOEBPKH_00171 |
170313 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
40G>A |
Glu14Lys |
M0212525 |
IHOEBPKH_00171 |
170450 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
177G>A |
Gln59Gln |
M0212526 |
IHOEBPKH_00171 |
170489 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
216A>T |
Ser72Ser |
M0212527 |
IHOEBPKH_00171 |
170528 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
255C>T |
Asp85Asp |
M0212528 |
IHOEBPKH_00171 |
170756 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
483T>C |
Ile161Ile |
M0212529 |
IHOEBPKH_00171 |
170782 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
509G>A |
Gly170Glu |
M0212530 |
IHOEBPKH_00171 |
170912 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
639C>T |
His213His |
M0212531 |
IHOEBPKH_00171 |
170917 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
644G>A |
Gly215Asp |
M0212532 |
IHOEBPKH_00171 |
171118 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
845T>C |
Val282Ala |
M0212533 |
IHOEBPKH_00172 |
171215 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
27A>G |
Thr9Thr |
M0212534 |
IHOEBPKH_00172 |
171251 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
63A>C |
Gly21Gly |
M0212535 |
IHOEBPKH_00173 |
171374 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
8G>A |
Arg3Gln |
M0212536 |
IHOEBPKH_00173 |
171431 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
65C>T |
Ala22Val |
M0212537 |
IHOEBPKH_00173 |
171445 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
79C>T |
Leu27Leu |
M0212538 |
IHOEBPKH_00173 |
171520 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
154A>C |
Lys52Gln |
M0212539 |
IHOEBPKH_00173 |
171522 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
156A>G |
Lys52Lys |
M0212540 |
IHOEBPKH_00064 |
72568 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
228G>A |
Leu76Leu |
M0212541 |
IHOEBPKH_00068 |
74950 |
6 |
Gut |
0.08 |
protein_coding |
synonymous_variant |
LOW |
192C>A |
Leu64Leu |
M0212542 |
IHOEBPKH_00068 |
74975 |
6 |
Gut |
0.08 |
protein_coding |
missense_variant |
MODERATE |
217G>A |
Ala73Thr |
M0212543 |
IHOEBPKH_00068 |
74977 |
6 |
Gut |
0.08 |
protein_coding |
synonymous_variant |
LOW |
219G>A |
Ala73Ala |
M0212544 |
IHOEBPKH_00068 |
74999 |
6 |
Gut |
0.08 |
protein_coding |
synonymous_variant |
LOW |
241C>T |
Leu81Leu |
M0212545 |
IHOEBPKH_00068 |
75004 |
6 |
Gut |
0.08 |
protein_coding |
synonymous_variant |
LOW |
246T>G |
Ala82Ala |
M0212546 |
IHOEBPKH_00068 |
75095 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
337C>T |
Leu113Leu |
M0212547 |
IHOEBPKH_00075 |
80239 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
357A>T |
Glu119Asp |
M0212548 |
IHOEBPKH_00075 |
80242 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
354A>G |
Pro118Pro |
M0212549 |
IHOEBPKH_00075 |
80251 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
345A>G |
Lys115Lys |
M0212550 |
IHOEBPKH_00075 |
80254 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
342T>C |
Arg114Arg |
M0212551 |
IHOEBPKH_00075 |
80260 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
336A>C |
Ile112Ile |
M0212552 |
IHOEBPKH_00075 |
80272 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
324T>C |
Val108Val |
M0212553 |
IHOEBPKH_00075 |
80275 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
321C>T |
Ser107Ser |
M0212554 |
IHOEBPKH_00075 |
80284 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
312T>C |
Ala104Ala |
M0212555 |
IHOEBPKH_00075 |
80290 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
306G>C |
Gly102Gly |
M0212556 |
IHOEBPKH_00075 |
80298 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
298A>C |
Asn100His |
M0212557 |
IHOEBPKH_00075 |
80586 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
10T>A |
Phe4Ile |
M0212558 |
IHOEBPKH_00080 |
86169 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
534A>G |
Gln178Gln |
M0212559 |
IHOEBPKH_00081 |
87374 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
63C>A |
Thr21Thr |
M0212560 |
IHOEBPKH_00094 |
95409 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
387G>A |
Lys129Lys |
M0212561 |
IHOEBPKH_00094 |
95593 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
203C>A |
Thr68Asn |
M0212562 |
IHOEBPKH_00064 |
72447 |
7 |
Gut |
0.09 |
protein_coding |
missense_variant |
MODERATE |
107C>T |
Ser36Phe |
M0212563 |
IHOEBPKH_00067 |
75405 |
3 |
Gut |
0.04 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-773T>C |
None |
M0212564 |
IHOEBPKH_00067 |
75417 |
3 |
Gut |
0.04 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-785G>A |
None |
M0212565 |
IHOEBPKH_00091 |
93638 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
268A>G |
Ser90Gly |
M0212566 |
IHOEBPKH_00091 |
93747 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
159G>A |
Lys53Lys |
M0212567 |
IHOEBPKH_00084 |
93982 |
3 |
Gut |
0.04 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4355G>A |
None |
M0212568 |
IHOEBPKH_00084 |
94304 |
3 |
Gut |
0.04 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4677A>C |
None |
M0212569 |
IHOEBPKH_00166 |
166725 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
402G>A |
Val134Val |
M0212570 |
IHOEBPKH_00166 |
166966 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
643A>C |
Arg215Arg |
M0212571 |
IHOEBPKH_00166 |
167187 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
864C>T |
Ala288Ala |
M0212572 |
IHOEBPKH_00168 |
167871 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
66A>G |
Lys22Lys |
M0212573 |
IHOEBPKH_00168 |
167877 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
72A>C |
Ala24Ala |
M0212574 |
IHOEBPKH_00168 |
167890 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
85C>A |
Leu29Met |
M0212575 |
IHOEBPKH_00168 |
167925 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
120C>A |
Ala40Ala |
M0212576 |
IHOEBPKH_00168 |
168057 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
252C>T |
Phe84Phe |
M0212577 |
IHOEBPKH_00168 |
168058 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
253A>C |
Arg85Arg |
M0212578 |
IHOEBPKH_00168 |
168060 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
255A>G |
Arg85Arg |
M0212579 |
IHOEBPKH_00168 |
168065 |
4 |
Gut |
0.05 |
protein_coding |
missense_variant |
MODERATE |
260A>G |
Asp87Gly |
M0212580 |
IHOEBPKH_00168 |
168066 |
5 |
Gut |
0.07 |
protein_coding |
missense_variant |
MODERATE |
261C>A |
Asp87Glu |
M0212581 |
IHOEBPKH_00168 |
168074 |
4 |
Gut |
0.05 |
protein_coding |
missense_variant |
MODERATE |
269G>A |
Gly90Glu |
M0212582 |
IHOEBPKH_00169 |
168309 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
181A>C |
Asn61His |
M0212583 |
IHOEBPKH_00062 |
71554 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
1552G>A |
Val518Ile |
M0212584 |
IHOEBPKH_00065 |
73262 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
320C>T |
Thr107Ile |
M0212585 |
IHOEBPKH_00065 |
73470 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
528C>T |
Asp176Asp |
M0212586 |
IHOEBPKH_00065 |
73792 |
4 |
Gut |
0.05 |
protein_coding |
missense_variant |
MODERATE |
850C>T |
Pro284Ser |
M0212587 |
IHOEBPKH_00067 |
74620 |
5 |
Gut |
0.07 |
protein_coding |
synonymous_variant |
LOW |
13C>T |
Leu5Leu |
M0212588 |
IHOEBPKH_00168 |
167823 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
18T>C |
Cys6Cys |
M0212589 |
IHOEBPKH_00169 |
168164 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
36G>A |
Arg12Arg |
M0212590 |
IHOEBPKH_00169 |
168170 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
42C>T |
Asp14Asp |
M0212591 |
IHOEBPKH_00169 |
168197 |
4 |
Gut |
0.05 |
protein_coding |
synonymous_variant |
LOW |
69A>G |
Pro23Pro |
M0212592 |
IHOEBPKH_00169 |
168220 |
3 |
Gut |
0.04 |
protein_coding |
missense_variant |
MODERATE |
92G>A |
Ser31Asn |
M0212593 |
IHOEBPKH_00168 |
168051 |
3 |
Gut |
0.04 |
protein_coding |
synonymous_variant |
LOW |
246C>G |
Pro82Pro |
Analysis of virulence factors contributing to bacterial pathogenicity
This table presents virulence factors identified within the plasmid cluster.
Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.
Gene Name |
vf_gene_id |
vf_name |
identity |
evalue |
qstart |
qend |
query_coverage |
subject_coverage |
vf_category |
gene_description |
condition |
Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact
This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.
Gene Name |
compound |
identity |
evalue |
qstart |
qend |
query_coverage |
subject_coverage |
group |
Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents
This table presents antimicrobial resistance genes identified within the plasmid cluster.
Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.
Gene Name |
aro_accession |
identity |
evalue |
qstart |
qend |
query_coverage |
subject_coverage |
drug_class |
amr_gene_family |
resistance_mechanism |
Analysis of pathogenicity genes to explore pathogen-host interactions
This table presents host pathogen-host interactions within the plasmid cluster.
Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.
Gene Name |
phi_molconn_id |
host gene_name |
identity |
evalue |
qstart |
qend |
query_coverage |
subject_coverage |
host_descripton |
disease_name |
function |
phenotype_of_mutant |
Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation
This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.
Gene Name |
cazy_id |
identity |
evalue |
qstart |
qend |
query_coverage |
subject_coverage |
Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification
This table presents transport proteins within the plasmid cluster.
Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.
Gene Name |
tcid |
identity |
evalue |
qstart |
qend |
query_coverage |
subject_coverage |
class_field |
class_term |
subclass |
subclass_term |
family |
family_term |