Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3412
  Reference Plasmid   SRR1950735_bin.3__k91_9597
  Reference Plasmid Size   9236
  Reference Plasmid GC Content   0.60
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0116944 NGMOKDAF_00001 4213 9 Skin 0.64 protein_coding upstream_gene_variant MODIFIER -2455G>C None
M0116945 NGMOKDAF_00001 4240 3 Skin 0.21 protein_coding upstream_gene_variant MODIFIER -2482T>G None
M0116946 NGMOKDAF_00001 4255 4 Skin 0.29 protein_coding upstream_gene_variant MODIFIER -2497T>G None
M0116947 NGMOKDAF_00004 4334 4 Skin 0.29 protein_coding missense_variant MODERATE 904A>G Thr302Ala
M0116948 NGMOKDAF_00004 4395 11 Skin 0.79 protein_coding synonymous_variant LOW 843T>C Ile281Ile
M0116949 NGMOKDAF_00004 4610 11 Skin 0.79 protein_coding missense_variant MODERATE 628A>G Thr210Ala
M0116950 NGMOKDAF_00004 4692 9 Skin 0.64 protein_coding missense_variant MODERATE 546A>G Ile182Met
M0116951 NGMOKDAF_00004 4863 3 Skin 0.21 protein_coding synonymous_variant LOW 375T>G Gly125Gly
M0116952 NGMOKDAF_00005 5531 7 Skin 0.50 protein_coding synonymous_variant LOW 267A>G Ala89Ala
M0116953 NGMOKDAF_00005 5532 6 Skin 0.43 protein_coding missense_variant MODERATE 266C>T Ala89Val
M0116954 NGMOKDAF_00005 5629 10 Skin 0.71 protein_coding missense_variant MODERATE 169A>G Thr57Ala
M0116955 NGMOKDAF_00005 5695 9 Skin 0.64 protein_coding missense_variant MODERATE 103T>G Ser35Ala
M0116956 NGMOKDAF_00005 5739 7 Skin 0.50 protein_coding missense_variant MODERATE 59G>C Cys20Ser
M0116957 NGMOKDAF_00001 5909 8 Skin 0.57 protein_coding upstream_gene_variant MODIFIER -4151C>A None
M0116958 NGMOKDAF_00001 5940 7 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -4182C>G None
M0116959 NGMOKDAF_00006 5964 8 Skin 0.57 protein_coding missense_variant MODERATE 1405G>A Glu469Lys
M0116960 NGMOKDAF_00006 5990 10 Skin 0.71 protein_coding missense_variant MODERATE 1379T>C Val460Ala
M0116961 NGMOKDAF_00006 6004 10 Skin 0.71 protein_coding synonymous_variant LOW 1365A>C Gly455Gly
M0116962 NGMOKDAF_00006 6372 8 Skin 0.57 protein_coding synonymous_variant LOW 997T>C Leu333Leu
M0116963 NGMOKDAF_00006 6650 9 Skin 0.64 protein_coding missense_variant MODERATE 719T>C Val240Ala
M0116964 NGMOKDAF_00006 6652 11 Skin 0.79 protein_coding synonymous_variant LOW 717A>G Arg239Arg
M0116965 NGMOKDAF_00006 6707 10 Skin 0.71 protein_coding missense_variant MODERATE 662T>C Val221Ala
M0116966 NGMOKDAF_00006 6979 11 Skin 0.79 protein_coding synonymous_variant LOW 390T>G Val130Val
M0116967 NGMOKDAF_00006 7213 10 Skin 0.71 protein_coding synonymous_variant LOW 156A>G Lys52Lys
M0116968 NGMOKDAF_00004 4832 5 Skin 0.36 protein_coding missense_variant MODERATE 406A>G Ile136Val
M0116969 NGMOKDAF_00005 5376 6 Skin 0.43 protein_coding missense_variant MODERATE 422A>G Glu141Gly
M0116970 NGMOKDAF_00006 5978 3 Skin 0.21 protein_coding missense_variant MODERATE 1391C>A Thr464Asn
M0116971 NGMOKDAF_00006 6901 5 Skin 0.36 protein_coding synonymous_variant LOW 468G>C Pro156Pro
M0116972 NGMOKDAF_00006 7291 5 Skin 0.36 protein_coding synonymous_variant LOW 78A>G Gly26Gly
M0116973 NGMOKDAF_00005 5627 3 Skin 0.21 protein_coding synonymous_variant LOW 171T>C Thr57Thr
M0116974 NGMOKDAF_00003 8119 3 Skin 0.21 protein_coding upstream_gene_variant MODIFIER -4587G>C None
M0116975 NGMOKDAF_00003 8124 3 Skin 0.21 protein_coding upstream_gene_variant MODIFIER -4592C>T None
M0116976 NGMOKDAF_00003 8125 3 Skin 0.21 protein_coding upstream_gene_variant MODIFIER -4593T>C None
M0116977 NGMOKDAF_00003 8126 3 Skin 0.21 protein_coding upstream_gene_variant MODIFIER -4594G>A None
M0116978 NGMOKDAF_00003 8129 3 Skin 0.21 protein_coding upstream_gene_variant MODIFIER -4597C>T None
M0116979 NGMOKDAF_00003 8191 3 Skin 0.21 protein_coding upstream_gene_variant MODIFIER -4659G>T None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term