Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3416
  Reference Plasmid   SRR2005645_bin.1_new__k91_11637
  Reference Plasmid Size   8275
  Reference Plasmid GC Content   0.31
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0117035 CBHJCKPE_00005 3599 3 Skin 0.20 protein_coding synonymous_variant LOW 108G>A Lys36Lys
M0117036 CBHJCKPE_00005 3634 8 Skin 0.53 protein_coding missense_variant MODERATE 143T>C Leu48Pro
M0117037 CBHJCKPE_00006 4975 5 Skin 0.33 protein_coding missense_variant MODERATE 342A>T Leu114Phe
M0117038 CBHJCKPE_00003 2176 3 Skin 0.20 protein_coding synonymous_variant LOW 303T>C Asn101Asn
M0117039 CBHJCKPE_00003 2185 3 Skin 0.20 protein_coding synonymous_variant LOW 312T>C Leu104Leu
M0117040 CBHJCKPE_00003 2212 3 Skin 0.20 protein_coding synonymous_variant LOW 339G>A Leu113Leu
M0117041 CBHJCKPE_00003 2225 3 Skin 0.20 protein_coding missense_variant MODERATE 352G>T Val118Phe
M0117042 CBHJCKPE_00003 2246 3 Skin 0.20 protein_coding missense_variant MODERATE 373A>G Ile125Val
M0117043 CBHJCKPE_00003 2269 3 Skin 0.20 protein_coding synonymous_variant LOW 396T>C Asn132Asn
M0117044 CBHJCKPE_00003 2314 3 Skin 0.20 protein_coding synonymous_variant LOW 441T>A Ile147Ile
M0117045 CBHJCKPE_00003 2395 4 Skin 0.27 protein_coding synonymous_variant LOW 522G>A Leu174Leu
M0117046 CBHJCKPE_00003 2398 3 Skin 0.20 protein_coding synonymous_variant LOW 525C>T Gly175Gly
M0117047 CBHJCKPE_00003 2401 4 Skin 0.27 protein_coding synonymous_variant LOW 528G>T Ala176Ala
M0117048 CBHJCKPE_00003 2428 3 Skin 0.20 protein_coding synonymous_variant LOW 555A>C Val185Val
M0117049 CBHJCKPE_00003 2437 4 Skin 0.27 protein_coding synonymous_variant LOW 564T>G Pro188Pro
M0117050 CBHJCKPE_00003 2461 3 Skin 0.20 protein_coding synonymous_variant LOW 588A>T Thr196Thr
M0117051 CBHJCKPE_00003 2509 3 Skin 0.20 protein_coding synonymous_variant LOW 636T>C Thr212Thr
M0117052 CBHJCKPE_00003 2521 3 Skin 0.20 protein_coding synonymous_variant LOW 648C>T Ala216Ala
M0117053 CBHJCKPE_00003 2614 3 Skin 0.20 protein_coding synonymous_variant LOW 741C>T Leu247Leu
M0117054 CBHJCKPE_00004 2694 4 Skin 0.27 protein_coding upstream_gene_variant MODIFIER -58C>T None
M0117055 CBHJCKPE_00004 2739 3 Skin 0.20 protein_coding upstream_gene_variant MODIFIER -13C>T None
M0117056 CBHJCKPE_00004 2778 3 Skin 0.20 protein_coding synonymous_variant LOW 27T>G Gly9Gly
M0117057 CBHJCKPE_00004 3212 4 Skin 0.27 protein_coding missense_variant MODERATE 461C>G Thr154Ser
M0117058 CBHJCKPE_00004 3477 4 Skin 0.27 protein_coding synonymous_variant LOW 726G>A Lys242Lys
M0117059 CBHJCKPE_00004 3486 4 Skin 0.27 protein_coding synonymous_variant LOW 735T>C Val245Val
M0117060 CBHJCKPE_00005 3527 4 Skin 0.27 protein_coding missense_variant MODERATE 36A>G Ile12Met
M0117061 CBHJCKPE_00005 3588 6 Skin 0.40 protein_coding missense_variant MODERATE 97T>G Ser33Ala
M0117062 CBHJCKPE_00005 4022 3 Skin 0.20 protein_coding synonymous_variant LOW 531C>T Arg177Arg
M0117063 CBHJCKPE_00005 4466 3 Skin 0.20 protein_coding missense_variant MODERATE 975T>G Asn325Lys
M0117064 CBHJCKPE_00005 4509 3 Skin 0.20 protein_coding missense_variant MODERATE 1018A>G Thr340Ala
M0117065 CBHJCKPE_00006 5008 3 Skin 0.20 protein_coding synonymous_variant LOW 375G>A Pro125Pro
M0117066 CBHJCKPE_00006 5302 3 Skin 0.20 protein_coding synonymous_variant LOW 669C>T Pro223Pro
M0117067 CBHJCKPE_00006 5313 3 Skin 0.20 protein_coding missense_variant MODERATE 680C>T Thr227Ile
M0117068 CBHJCKPE_00006 5321 3 Skin 0.20 protein_coding missense_variant MODERATE 688G>A Asp230Asn
M0117069 CBHJCKPE_00006 5350 3 Skin 0.20 protein_coding synonymous_variant LOW 717T>C Asp239Asp
M0117070 CBHJCKPE_00006 5519 3 Skin 0.20 protein_coding missense_variant MODERATE 886T>C Phe296Leu
M0117071 CBHJCKPE_00006 5521 3 Skin 0.20 protein_coding synonymous_variant LOW 888T>C Phe296Phe
M0117072 CBHJCKPE_00002 1779 5 Skin 0.33 protein_coding synonymous_variant LOW 993T>G Gly331Gly
M0117073 CBHJCKPE_00004 3280 4 Skin 0.27 protein_coding synonymous_variant LOW 529C>T Leu177Leu
M0117074 CBHJCKPE_00004 3294 4 Skin 0.27 protein_coding synonymous_variant LOW 543G>A Thr181Thr
M0117075 CBHJCKPE_00004 3312 4 Skin 0.27 protein_coding synonymous_variant LOW 561T>C Thr187Thr
M0117076 CBHJCKPE_00005 4268 3 Skin 0.20 protein_coding synonymous_variant LOW 777T>C Ser259Ser
M0117077 CBHJCKPE_00005 4271 3 Skin 0.20 protein_coding synonymous_variant LOW 780C>T Asn260Asn
M0117078 CBHJCKPE_00005 4274 3 Skin 0.20 protein_coding synonymous_variant LOW 783A>T Leu261Leu
M0117079 CBHJCKPE_00004 2865 3 Skin 0.20 protein_coding synonymous_variant LOW 114A>T Thr38Thr
M0117080 CBHJCKPE_00004 2922 4 Skin 0.27 protein_coding synonymous_variant LOW 171G>A Ala57Ala
M0117081 CBHJCKPE_00004 2937 3 Skin 0.20 protein_coding synonymous_variant LOW 186C>T Tyr62Tyr
M0117082 CBHJCKPE_00004 2959 3 Skin 0.20 protein_coding missense_variant MODERATE 208G>A Val70Ile
M0117083 CBHJCKPE_00004 3072 3 Skin 0.20 protein_coding synonymous_variant LOW 321A>G Gly107Gly
M0117084 CBHJCKPE_00006 5490 3 Skin 0.20 protein_coding missense_variant MODERATE 857C>T Ala286Val
M0117085 CBHJCKPE_00006 5491 3 Skin 0.20 protein_coding synonymous_variant LOW 858G>A Ala286Ala
M0117086 CBHJCKPE_00002 1437 4 Skin 0.27 protein_coding synonymous_variant LOW 651C>A Gly217Gly
M0117087 CBHJCKPE_00006 5212 3 Skin 0.20 protein_coding synonymous_variant LOW 579T>C His193His
M0117088 CBHJCKPE_00007 6188 3 Skin 0.20 protein_coding synonymous_variant LOW 99C>T Asn33Asn
M0117089 CBHJCKPE_00007 6523 3 Skin 0.20 protein_coding missense_variant MODERATE 434G>C Gly145Ala
M0117090 CBHJCKPE_00007 6535 3 Skin 0.20 protein_coding missense_variant MODERATE 446G>T Trp149Leu
M0117091 CBHJCKPE_00002 6684 3 Skin 0.20 protein_coding downstream_gene_variant MODIFIER *4803T>C None
M0117092 CBHJCKPE_00002 6795 3 Skin 0.20 protein_coding downstream_gene_variant MODIFIER *4914T>C None
M0117093 CBHJCKPE_00008 7188 3 Skin 0.20 protein_coding synonymous_variant LOW 1014A>G Thr338Thr
M0117094 CBHJCKPE_00008 7979 3 Skin 0.20 protein_coding missense_variant MODERATE 223A>G Ile75Val
M0117095 CBHJCKPE_00008 8037 3 Skin 0.20 protein_coding synonymous_variant LOW 165T>C Pro55Pro
M0117096 CBHJCKPE_00008 8055 3 Skin 0.20 protein_coding synonymous_variant LOW 147A>T Ala49Ala
M0117097 CBHJCKPE_00008 8058 3 Skin 0.20 protein_coding synonymous_variant LOW 144T>C Val48Val
M0117098 CBHJCKPE_00008 8070 3 Skin 0.20 protein_coding synonymous_variant LOW 132G>A Pro44Pro
M0117099 CBHJCKPE_00008 8173 3 Skin 0.20 protein_coding missense_variant MODERATE 29A>G Asn10Ser
M0117100 CBHJCKPE_00002 874 3 Skin 0.20 protein_coding missense_variant MODERATE 88G>A Gly30Ser
M0117101 CBHJCKPE_00001 412 3 Skin 0.20 protein_coding synonymous_variant LOW 177T>C Ser59Ser
M0117102 CBHJCKPE_00001 460 3 Skin 0.20 protein_coding missense_variant MODERATE 225G>C Lys75Asn
M0117103 CBHJCKPE_00001 728 3 Skin 0.20 protein_coding missense_variant MODERATE 493G>A Asp165Asn
M0117104 CBHJCKPE_00001 739 3 Skin 0.20 protein_coding synonymous_variant LOW 504G>T Val168Val
M0117105 CBHJCKPE_00002 1434 3 Skin 0.20 protein_coding synonymous_variant LOW 648T>C Phe216Phe
M0117106 CBHJCKPE_00002 1503 3 Skin 0.20 protein_coding synonymous_variant LOW 717C>T Asn239Asn
M0117107 CBHJCKPE_00002 1510 4 Skin 0.27 protein_coding missense_variant MODERATE 724C>G His242Asp
M0117108 CBHJCKPE_00002 1512 4 Skin 0.27 protein_coding missense_variant MODERATE 726C>A His242Gln
M0117109 CBHJCKPE_00002 1539 4 Skin 0.27 protein_coding synonymous_variant LOW 753T>C Val251Val
M0117110 CBHJCKPE_00002 1710 3 Skin 0.20 protein_coding synonymous_variant LOW 924T>C Cys308Cys
M0117111 CBHJCKPE_00002 1716 3 Skin 0.20 protein_coding synonymous_variant LOW 930T>C Asp310Asp
M0117112 CBHJCKPE_00003 1878 3 Skin 0.20 protein_coding missense_variant MODERATE 5A>G His2Arg
M0117113 CBHJCKPE_00003 2146 4 Skin 0.27 protein_coding synonymous_variant LOW 273T>C Leu91Leu
M0117114 CBHJCKPE_00005 4124 3 Skin 0.20 protein_coding synonymous_variant LOW 633T>A Pro211Pro
M0117115 CBHJCKPE_00005 4136 3 Skin 0.20 protein_coding synonymous_variant LOW 645G>T Gly215Gly
M0117116 CBHJCKPE_00005 4157 3 Skin 0.20 protein_coding synonymous_variant LOW 666T>C Thr222Thr






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
CBHJCKPE_00002 3.A.1.11.8 84.9 3.8e-180 1 364 1.0000 1.3736 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
CBHJCKPE_00003 3.A.1.11.8 80.5 1.5e-117 1 267 1.0000 1.0000 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
CBHJCKPE_00004 3.A.1.11.8 85.3 8.8e-112 1 245 0.9919 0.9245 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
CBHJCKPE_00005 3.A.1.11.8 78.4 1.2e-170 1 357 1.0000 1.3472 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily